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Items: 1 to 50 of 116

1.

Macrophage lineages in heart valve development and disease.

Kim AJ, Xu N, Yutzey KE.

Cardiovasc Res. 2020 Mar 14. pii: cvaa062. doi: 10.1093/cvr/cvaa062. [Epub ahead of print]

PMID:
32170926
2.

Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination.

Xu N, Gulick J, Osinska H, Yu Y, McLendon PM, Shay-Winkler K, Robbins J, Yutzey KE.

Circ Res. 2020 Mar 27;126(7):907-922. doi: 10.1161/CIRCRESAHA.119.316444. Epub 2020 Feb 21.

PMID:
32081062
3.

Cytokinesis, Beta-Blockers, and Congenital Heart Disease.

Yutzey KE.

N Engl J Med. 2020 Jan 16;382(3):291-293. doi: 10.1056/NEJMcibr1913824. No abstract available.

PMID:
31940705
4.

Timing of Repair in Tetralogy of Fallot: Effects on Outcomes and Myocardial Health.

Peck D, Tretter J, Possner M, Yutzey K, Zafar F, Morales D, Alsaied T.

Cardiol Rev. 2020 Jan 2. doi: 10.1097/CRD.0000000000000293. [Epub ahead of print]

PMID:
31934899
5.

Deficiency of Circulating Monocytes Ameliorates the Progression of Myxomatous Valve Degeneration in Marfan Syndrome.

Kim AJ, Xu N, Umeyama K, Hulin A, Ponny SR, Vagnozzi RJ, Green EA, Hanson P, McManus BM, Nagashima H, Yutzey KE.

Circulation. 2020 Jan 14;141(2):132-146. doi: 10.1161/CIRCULATIONAHA.119.042391. Epub 2020 Jan 13.

PMID:
31928435
6.

Scar Formation with Decreased Cardiac Function Following Ischemia/Reperfusion Injury in 1 Month Old Swine.

Agnew EJ, Velayutham N, Matos Ortiz G, Alfieri CM, Hortells L, Moore V, Riggs KW, Baker RS, Gibson AM, Ponny SR, Alsaied T, Zafar F, Yutzey KE.

J Cardiovasc Dev Dis. 2019 Dec 18;7(1). pii: E1. doi: 10.3390/jcdd7010001.

7.

Cardiac Fibroblasts and the Extracellular Matrix in Regenerative and Nonregenerative Hearts.

Hortells L, Johansen AKZ, Yutzey KE.

J Cardiovasc Dev Dis. 2019 Aug 20;6(3). pii: E29. doi: 10.3390/jcdd6030029. Review.

8.

Postnatal Cardiac Development and Regenerative Potential in Large Mammals.

Velayutham N, Agnew EJ, Yutzey KE.

Pediatr Cardiol. 2019 Oct;40(7):1345-1358. doi: 10.1007/s00246-019-02163-7. Epub 2019 Jul 25. Review.

PMID:
31346664
9.

Calcification and extracellular matrix dysregulation in human postmortem and surgical aortic valves.

Gomez-Stallons MV, Tretter JT, Hassel K, Gonzalez-Ramos O, Amofa D, Ollberding NJ, Mazur W, Choo JK, Smith JM, Kereiakes DJ, Yutzey KE.

Heart. 2019 Nov;105(21):1616-1621. doi: 10.1136/heartjnl-2019-314879. Epub 2019 Jun 5.

PMID:
31171628
10.

Maturation of heart valve cell populations during postnatal remodeling.

Hulin A, Hortells L, Gomez-Stallons MV, O'Donnell A, Chetal K, Adam M, Lancellotti P, Oury C, Potter SS, Salomonis N, Yutzey KE.

Development. 2019 Mar 12;146(12). pii: dev173047. doi: 10.1242/dev.173047.

11.

At the Heart of the Matter: A Tribute to Roger Markwald.

Yutzey KE.

Anat Rec (Hoboken). 2019 Jan;302(1):12-13. doi: 10.1002/ar.24052. No abstract available.

12.

Endothelial Cell Lineage Analysis Does Not Provide Evidence for EMT in Adult Valve Homeostasis and Disease.

Kim AJ, Alfieri CM, Yutzey KE.

Anat Rec (Hoboken). 2019 Jan;302(1):125-135. doi: 10.1002/ar.23916. Epub 2018 Oct 10.

13.

FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme.

Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV.

Dev Biol. 2018 Nov 1;443(1):50-63. doi: 10.1016/j.ydbio.2018.08.011. Epub 2018 Aug 25.

14.

Molecular Mechanisms of Heart Valve Development and Disease.

Gomez Stallons MV, Wirrig-Schwendeman EE, Fang M, Cheek JD, Alfieri CM, Hinton RB, Yutzey KE.

In: Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H, editors. Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology [Internet]. Tokyo: Springer; 2016. Chapter 18.
2016 Jun 25.

15.

Macrophage Transitions in Heart Valve Development and Myxomatous Valve Disease.

Hulin A, Anstine LJ, Kim AJ, Potter SJ, DeFalco T, Lincoln J, Yutzey KE.

Arterioscler Thromb Vasc Biol. 2018 Mar;38(3):636-644. doi: 10.1161/ATVBAHA.117.310667. Epub 2018 Jan 18.

16.

Loss of β-catenin in resident cardiac fibroblasts attenuates fibrosis induced by pressure overload in mice.

Xiang FL, Fang M, Yutzey KE.

Nat Commun. 2017 Sep 28;8(1):712. doi: 10.1038/s41467-017-00840-w.

17.

Hypoxia promotes primitive glycosaminoglycan-rich extracellular matrix composition in developing heart valves.

Amofa D, Hulin A, Nakada Y, Sadek HA, Yutzey KE.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1143-H1154. doi: 10.1152/ajpheart.00209.2017. Epub 2017 Aug 25.

18.

Cardiomyocyte Proliferation: Teaching an Old Dogma New Tricks.

Yutzey KE.

Circ Res. 2017 Feb 17;120(4):627-629. doi: 10.1161/CIRCRESAHA.116.310058. No abstract available.

19.

Loss of Axin2 results in impaired heart valve maturation and subsequent myxomatous valve disease.

Hulin A, Moore V, James JM, Yutzey KE.

Cardiovasc Res. 2017 Jan;113(1):40-51. doi: 10.1093/cvr/cvw229. Epub 2016 Nov 7.

20.

Developmental Mechanisms of Aortic Valve Malformation and Disease.

Wu B, Wang Y, Xiao F, Butcher JT, Yutzey KE, Zhou B.

Annu Rev Physiol. 2017 Feb 10;79:21-41. doi: 10.1146/annurev-physiol-022516-034001. Epub 2016 Dec 9. Review.

PMID:
27959615
21.

Bone Morphogenetic Protein Signaling Is Required for Aortic Valve Calcification.

Gomez-Stallons MV, Wirrig-Schwendeman EE, Hassel KR, Conway SJ, Yutzey KE.

Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1398-405. doi: 10.1161/ATVBAHA.116.307526. Epub 2016 May 19.

22.

Cardiac Fibrosis: The Fibroblast Awakens.

Travers JG, Kamal FA, Robbins J, Yutzey KE, Blaxall BC.

Circ Res. 2016 Mar 18;118(6):1021-40. doi: 10.1161/CIRCRESAHA.115.306565. Review.

23.

Overexpression of Tbx20 in Adult Cardiomyocytes Promotes Proliferation and Improves Cardiac Function After Myocardial Infarction.

Xiang FL, Guo M, Yutzey KE.

Circulation. 2016 Mar 15;133(11):1081-92. doi: 10.1161/CIRCULATIONAHA.115.019357. Epub 2016 Feb 3.

24.

Epicardium-derived fibroblasts in heart development and disease.

Fang M, Xiang FL, Braitsch CM, Yutzey KE.

J Mol Cell Cardiol. 2016 Feb;91:23-7. doi: 10.1016/j.yjmcc.2015.12.019. Epub 2015 Dec 22. Review.

25.

Notch-Tnf signalling is required for development and homeostasis of arterial valves.

Wang Y, Wu B, Farrar E, Lui W, Lu P, Zhang D, Alfieri CM, Mao K, Chu M, Yang D, Xu D, Rauchman M, Taylor V, Conway SJ, Yutzey KE, Butcher JT, Zhou B.

Eur Heart J. 2017 Mar 1;38(9):675-686. doi: 10.1093/eurheartj/ehv520.

26.

Cardiac fibroblasts: from development to heart failure.

Moore-Morris T, Guimarães-Camboa N, Yutzey KE, Pucéat M, Evans SM.

J Mol Med (Berl). 2015 Aug;93(8):823-30. doi: 10.1007/s00109-015-1314-y. Epub 2015 Jul 14. Review.

27.

Regenerative biology: Neuregulin 1 makes heart muscle.

Yutzey KE.

Nature. 2015 Apr 23;520(7548):445-6. doi: 10.1038/520445a. No abstract available.

PMID:
25903623
28.

COX2 inhibition reduces aortic valve calcification in vivo.

Wirrig EE, Gomez MV, Hinton RB, Yutzey KE.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):938-47. doi: 10.1161/ATVBAHA.114.305159. Epub 2015 Feb 26.

29.

Cross Talk between NOTCH Signaling and Biomechanics in Human Aortic Valve Disease Pathogenesis.

Godby RC, Munjal C, Opoka AM, Smith JM, Yutzey KE, Narmoneva DA, Hinton RB.

J Cardiovasc Dev Dis. 2014 Dec;1(3):237-256. doi: 10.3390/jcdd1030237. Epub 2014 Dec 1.

30.

Loss of β-catenin promotes chondrogenic differentiation of aortic valve interstitial cells.

Fang M, Alfieri CM, Hulin A, Conway SJ, Yutzey KE.

Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2601-8. doi: 10.1161/ATVBAHA.114.304579. Epub 2014 Oct 23.

31.

Genome-wide Twist1 occupancy in endocardial cushion cells, embryonic limb buds, and peripheral nerve sheath tumor cells.

Lee MP, Ratner N, Yutzey KE.

BMC Genomics. 2014 Sep 28;15:821. doi: 10.1186/1471-2164-15-821.

32.

Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease.

Yutzey KE, Demer LL, Body SC, Huggins GS, Towler DA, Giachelli CM, Hofmann-Bowman MA, Mortlock DP, Rogers MB, Sadeghi MM, Aikawa E.

Arterioscler Thromb Vasc Biol. 2014 Nov;34(11):2387-93. doi: 10.1161/ATVBAHA.114.302523. Epub 2014 Sep 4. Review.

33.

Cardiovascular biology: Switched at birth.

Yutzey KE.

Nature. 2014 May 29;509(7502):572-3. doi: 10.1038/509572a. No abstract available.

PMID:
24870539
34.

Congenital heart disease linked to maternal autoimmunity against cardiac myosin.

Cole CR, Yutzey KE, Brar AK, Goessling LS, Van Vickle-Chavez SJ, Cunningham MW, Eghtesady P.

J Immunol. 2014 May 1;192(9):4074-82. doi: 10.4049/jimmunol.1301264. Epub 2014 Mar 26.

35.

Conserved transcriptional regulatory mechanisms in aortic valve development and disease.

Wirrig EE, Yutzey KE.

Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):737-41. doi: 10.1161/ATVBAHA.113.302071. Review.

36.

A twist of proepicardial fate.

Yutzey KE.

Circ Res. 2013 Oct 25;113(10):1106-8. doi: 10.1161/CIRCRESAHA.113.302588. No abstract available.

PMID:
24158573
37.

Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease.

Braitsch CM, Kanisicak O, van Berlo JH, Molkentin JD, Yutzey KE.

J Mol Cell Cardiol. 2013 Dec;65:108-19. doi: 10.1016/j.yjmcc.2013.10.005. Epub 2013 Oct 17.

38.

Transcriptional Control of Cell Lineage Development in Epicardium-Derived Cells.

Braitsch CM, Yutzey KE.

J Dev Biol. 2013 Sep;1(2):92-111. Epub 2013 Jul 3.

39.

Tbx20 promotes cardiomyocyte proliferation and persistence of fetal characteristics in adult mouse hearts.

Chakraborty S, Sengupta A, Yutzey KE.

J Mol Cell Cardiol. 2013 Sep;62:203-13. doi: 10.1016/j.yjmcc.2013.05.018. Epub 2013 Jun 7.

PMID:
23751911
40.

GENE EXPRESSION AND COLLAGEN FIBER MICROMECHANICAL INTERACTIONS OF THE SEMILUNAR HEART VALVE INTERSTITIAL CELL.

Carruthers CA, Alfieri CM, Joyce EM, Watkins SC, Yutzey KE, Sacks MS.

Cell Mol Bioeng. 2012 Sep 1;5(3):254-265. Epub 2012 May 1.

41.

FoxO1 and FoxM1 transcription factors have antagonistic functions in neonatal cardiomyocyte cell-cycle withdrawal and IGF1 gene regulation.

Sengupta A, Kalinichenko VV, Yutzey KE.

Circ Res. 2013 Jan 18;112(2):267-77. doi: 10.1161/CIRCRESAHA.112.277442. Epub 2012 Nov 14.

42.

Placement of an elastic biodegradable cardiac patch on a subacute infarcted heart leads to cellularization with early developmental cardiomyocyte characteristics.

Fujimoto KL, Tobita K, Guan J, Hashizume R, Takanari K, Alfieri CM, Yutzey KE, Wagner WR.

J Card Fail. 2012 Jul;18(7):585-95. doi: 10.1016/j.cardfail.2012.05.006.

43.

Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the developing heart.

Braitsch CM, Combs MD, Quaggin SE, Yutzey KE.

Dev Biol. 2012 Aug 15;368(2):345-57. doi: 10.1016/j.ydbio.2012.06.002. Epub 2012 Jun 9.

44.

FoxO1 is required in endothelial but not myocardial cell lineages during cardiovascular development.

Sengupta A, Chakraborty S, Paik J, Yutzey KE, Evans-Anderson HJ.

Dev Dyn. 2012 Apr;241(4):803-13. doi: 10.1002/dvdy.23759.

45.

Notch signaling and the developing skeleton.

Mead TJ, Yutzey KE.

Adv Exp Med Biol. 2012;727:114-30. doi: 10.1007/978-1-4614-0899-4_9. Review.

PMID:
22399343
46.

Notch pathway regulation of neural crest cell development in vivo.

Mead TJ, Yutzey KE.

Dev Dyn. 2012 Feb;241(2):376-89. doi: 10.1002/dvdy.23717. Epub 2012 Jan 3.

47.

Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development.

Le TT, Conley KW, Mead TJ, Rowan S, Yutzey KE, Brown NL.

Dev Dyn. 2012 Mar;241(3):493-504. doi: 10.1002/dvdy.23739. Epub 2012 Jan 25.

48.

Differential activation of valvulogenic, chondrogenic, and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease.

Cheek JD, Wirrig EE, Alfieri CM, James JF, Yutzey KE.

J Mol Cell Cardiol. 2012 Mar;52(3):689-700. doi: 10.1016/j.yjmcc.2011.12.013. Epub 2012 Jan 10.

49.

Twist1 directly regulates genes that promote cell proliferation and migration in developing heart valves.

Lee MP, Yutzey KE.

PLoS One. 2011;6(12):e29758. doi: 10.1371/journal.pone.0029758. Epub 2011 Dec 29.

50.

Tbx20 regulation of cardiac cell proliferation and lineage specialization during embryonic and fetal development in vivo.

Chakraborty S, Yutzey KE.

Dev Biol. 2012 Mar 1;363(1):234-46. doi: 10.1016/j.ydbio.2011.12.034. Epub 2011 Dec 29.

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