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Items: 23

1.

Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities.

Bäck M, Yurdagul A Jr, Tabas I, Öörni K, Kovanen PT.

Nat Rev Cardiol. 2019 Jul;16(7):389-406. doi: 10.1038/s41569-019-0169-2. Review.

PMID:
30846875
2.

An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1.

Zheng Z, Nayak L, Wang W, Yurdagul A Jr, Wang X, Cai B, Lapping S, Ozcan L, Ramakrishnan R, Pestell RG, Jain MK, Tabas I.

Blood. 2019 Feb 14;133(7):743-753. doi: 10.1182/blood-2018-07-864843. Epub 2018 Dec 1.

PMID:
30504459
3.

Endothelial FN (Fibronectin) Deposition by α5β1 Integrins Drives Atherogenic Inflammation.

Al-Yafeai Z, Yurdagul A Jr, Peretik JM, Alfaidi M, Murphy PA, Orr AW.

Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2601-2614. doi: 10.1161/ATVBAHA.118.311705.

PMID:
30354234
4.

Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution.

Proto JD, Doran AC, Gusarova G, Yurdagul A Jr, Sozen E, Subramanian M, Islam MN, Rymond CC, Du J, Hook J, Kuriakose G, Bhattacharya J, Tabas I.

Immunity. 2018 Oct 16;49(4):666-677.e6. doi: 10.1016/j.immuni.2018.07.015. Epub 2018 Oct 2.

PMID:
30291029
5.

Cystathionine γ-Lyase Modulates Flow-Dependent Vascular Remodeling.

Yuan S, Yurdagul A Jr, Peretik JM, Alfaidi M, Al Yafeai Z, Pardue S, Kevil CG, Orr AW.

Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2126-2136. doi: 10.1161/ATVBAHA.118.311402. Erratum in: Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):e82.

6.

EphA2 stimulates VCAM-1 expression through calcium-dependent NFAT1 activity.

Funk SD, Finney AC, Yurdagul A Jr, Pattillo CB, Orr AW.

Cell Signal. 2018 Sep;49:30-38. doi: 10.1016/j.cellsig.2018.05.008. Epub 2018 May 21.

7.

Mechanisms and Consequences of Defective Efferocytosis in Atherosclerosis.

Yurdagul A Jr, Doran AC, Cai B, Fredman G, Tabas IA.

Front Cardiovasc Med. 2018 Jan 8;4:86. doi: 10.3389/fcvm.2017.00086. eCollection 2017. Review.

8.

The Type 1 Diabetes-Resistance Locus Idd22 Controls Trafficking of Autoreactive CTLs into the Pancreatic Islets of NOD Mice.

Whitener RL, Gallo Knight L, Li J, Knapp S, Zhang S, Annamalai M, Pliner VM, Fu D, Radichev I, Amatya C, Savinov A, Yurdagul A Jr, Yuan S, Glawe J, Kevil CG, Chen J, Stimpson SE, Mathews CE.

J Immunol. 2017 Dec 15;199(12):3991-4000. doi: 10.4049/jimmunol.1602037. Epub 2017 Nov 6.

9.

Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages.

Wang Y, Subramanian M, Yurdagul A Jr, Barbosa-Lorenzi VC, Cai B, de Juan-Sanz J, Ryan TA, Nomura M, Maxfield FR, Tabas I.

Cell. 2017 Oct 5;171(2):331-345.e22. doi: 10.1016/j.cell.2017.08.041. Epub 2017 Sep 21.

10.

EphA2 Expression Regulates Inflammation and Fibroproliferative Remodeling in Atherosclerosis.

Finney AC, Funk SD, Green JM, Yurdagul A Jr, Rana MA, Pistorius R, Henry M, Yurochko A, Pattillo CB, Traylor JG, Chen J, Woolard MD, Kevil CG, Orr AW.

Circulation. 2017 Aug 8;136(6):566-582. doi: 10.1161/CIRCULATIONAHA.116.026644. Epub 2017 May 9.

11.

The arterial microenvironment: the where and why of atherosclerosis.

Yurdagul A Jr, Finney AC, Woolard MD, Orr AW.

Biochem J. 2016 May 15;473(10):1281-95. doi: 10.1042/BJ20150844. Review.

12.

Oxidized LDL induces FAK-dependent RSK signaling to drive NF-κB activation and VCAM-1 expression.

Yurdagul A Jr, Sulzmaier FJ, Chen XL, Pattillo CB, Schlaepfer DD, Orr AW.

J Cell Sci. 2016 Apr 15;129(8):1580-91. doi: 10.1242/jcs.182097. Epub 2016 Feb 18.

13.

Blood Brothers: Hemodynamics and Cell-Matrix Interactions in Endothelial Function.

Yurdagul A Jr, Orr AW.

Antioxid Redox Signal. 2016 Sep 1;25(7):415-34. doi: 10.1089/ars.2015.6525. Epub 2016 Feb 19. Review.

14.

αvβ3 Integrins Mediate Flow-Induced NF-κB Activation, Proinflammatory Gene Expression, and Early Atherogenic Inflammation.

Chen J, Green J, Yurdagul A Jr, Albert P, McInnis MC, Orr AW.

Am J Pathol. 2015 Sep;185(9):2575-89. doi: 10.1016/j.ajpath.2015.05.013. Epub 2015 Jul 26.

15.

Recruitment of the adaptor protein Nck to PECAM-1 couples oxidative stress to canonical NF-κB signaling and inflammation.

Chen J, Leskov IL, Yurdagul A Jr, Thiel B, Kevil CG, Stokes KY, Orr AW.

Sci Signal. 2015 Feb 24;8(365):ra20. doi: 10.1126/scisignal.2005648.

16.

α5β1 integrin signaling mediates oxidized low-density lipoprotein-induced inflammation and early atherosclerosis.

Yurdagul A Jr, Green J, Albert P, McInnis MC, Mazar AP, Orr AW.

Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1362-73. doi: 10.1161/ATVBAHA.114.303863. Epub 2014 May 15.

17.

Flow patterns regulate hyperglycemia-induced subendothelial matrix remodeling during early atherogenesis.

Green J, Yurdagul A Jr, McInnis MC, Albert P, Orr AW.

Atherosclerosis. 2014 Feb;232(2):277-84. doi: 10.1016/j.atherosclerosis.2013.11.052. Epub 2013 Dec 8.

18.

Resveratrol promotes endothelial cell wound healing under laminar shear stress through an estrogen receptor-α-dependent pathway.

Yurdagul A Jr, Kleinedler JJ, McInnis MC, Khandelwal AR, Spence AL, Orr AW, Dugas TR.

Am J Physiol Heart Circ Physiol. 2014 Mar;306(6):H797-806. doi: 10.1152/ajpheart.00892.2013. Epub 2014 Jan 24.

19.

Altered nitric oxide production mediates matrix-specific PAK2 and NF-κB activation by flow.

Yurdagul A Jr, Chen J, Funk SD, Albert P, Kevil CG, Orr AW.

Mol Biol Cell. 2013 Feb;24(3):398-408. doi: 10.1091/mbc.E12-07-0513. Epub 2012 Nov 21.

20.

Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes.

Funk SD, Yurdagul A Jr, Orr AW.

Int J Vasc Med. 2012;2012:569654. doi: 10.1155/2012/569654. Epub 2012 Feb 14.

21.

EphA2 activation promotes the endothelial cell inflammatory response: a potential role in atherosclerosis.

Funk SD, Yurdagul A Jr, Albert P, Traylor JG Jr, Jin L, Chen J, Orr AW.

Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):686-95. doi: 10.1161/ATVBAHA.111.242792. Epub 2012 Jan 12.

22.

Matrix-specific protein kinase A signaling regulates p21-activated kinase activation by flow in endothelial cells.

Funk SD, Yurdagul A Jr, Green JM, Jhaveri KA, Schwartz MA, Orr AW.

Circ Res. 2010 Apr 30;106(8):1394-403. doi: 10.1161/CIRCRESAHA.109.210286. Epub 2010 Mar 11.

23.

Molecular mechanisms of collagen isotype-specific modulation of smooth muscle cell phenotype.

Orr AW, Lee MY, Lemmon JA, Yurdagul A Jr, Gomez MF, Bortz PD, Wamhoff BR.

Arterioscler Thromb Vasc Biol. 2009 Feb;29(2):225-31. doi: 10.1161/ATVBAHA.108.178749. Epub 2008 Nov 20.

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