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Items: 1 to 50 of 86

1.

Role of plasminogen activator inhibitor-1 in methotrexate-induced epithelial-mesenchymal transition in alveolar epithelial A549 cells.

Yamagami Y, Kawami M, Ojima T, Futatsugi S, Yumoto R, Takano M.

Biochem Biophys Res Commun. 2020 Feb 26. pii: S0006-291X(20)30412-5. doi: 10.1016/j.bbrc.2020.02.131. [Epub ahead of print]

PMID:
32113686
2.

Suppression of P-glycoprotein by cigarette smoke extract in human lung-derived A549/P-gp cells.

Takano M, Higa S, Furuichi Y, Naka R, Yumoto R.

Drug Metab Pharmacokinet. 2019 Dec 20. pii: S1347-4367(19)30235-6. doi: 10.1016/j.dmpk.2019.12.001. [Epub ahead of print]

PMID:
32037157
3.

Effect of transforming growth factor-β1 on functional expression of monocarboxylate transporter 1 in alveolar epithelial A549 cells.

Uddin M, Kawami M, Yumoto R, Takano M.

Naunyn Schmiedebergs Arch Pharmacol. 2020 Jan 3. doi: 10.1007/s00210-019-01802-3. [Epub ahead of print]

PMID:
31900520
4.

Anticancer Drug-Induced Epithelial-Mesenchymal Transition via p53/miR-34a axis in A549/ABCA3 Cells.

Yamamoto A, Kawami M, Konaka T, Takenaka S, Yumoto R, Takano M.

J Pharm Pharm Sci. 2019;22(1):516-524. doi: 10.18433/jpps30660.

5.

Investigation on inhibitory effect of folic acid on methotrexate-induced epithelial-mesenchymal transition focusing on dihydrofolate reductase.

Kawami M, Honda N, Hara T, Yumoto R, Takano M.

Drug Metab Pharmacokinet. 2019 Dec;34(6):396-399. doi: 10.1016/j.dmpk.2019.08.003. Epub 2019 Aug 16.

PMID:
31601464
6.

Association of cell cycle arrest with anticancer drug-induced epithelial-mesenchymal transition in alveolar epithelial cells.

Kawami M, Harada R, Ojima T, Yamagami Y, Yumoto R, Takano M.

Toxicology. 2019 Aug 1;424:152231. doi: 10.1016/j.tox.2019.06.002. Epub 2019 Jun 4.

PMID:
31170432
7.

Role of peptide transporter 2 and MAPK signaling pathways in the innate immune response induced by bacterial peptides in alveolar epithelial cells.

Takano M, Takeuchi T, Kuriyama S, Yumoto R.

Life Sci. 2019 Jul 15;229:173-179. doi: 10.1016/j.lfs.2019.05.042. Epub 2019 May 16.

PMID:
31103606
8.

Functional expression of breast cancer resistance protein and cholesterol effect in human erythrocyte membranes.

Takano M, Higashi M, Ito H, Toyota S, Hirabayashi Y, Yumoto R.

Pharmazie. 2018 Dec 1;73(12):700-705. doi: 10.1691/ph.2018.8724.

PMID:
30522552
9.

Reduced folate carrier-mediated methotrexate transport in human distal lung epithelial NCl-H441 cells.

Kawami M, Honda N, Miyamoto M, Yumoto R, Takano M.

J Pharm Pharmacol. 2019 Feb;71(2):167-175. doi: 10.1111/jphp.13022. Epub 2018 Oct 15.

PMID:
30324648
10.

Transport of AOPP-Albumin into Human Alveolar Epithelial A549 Cell.

Kawami M, Shimonakamura T, Yumoto R, Takano M.

J Pharm Pharm Sci. 2018;21(1):247-255. doi: 10.18433/jpps29905.

11.

Folic acid prevents methotrexate-induced epithelial-mesenchymal transition via suppression of secreted factors from the human alveolar epithelial cell line A549.

Kawami M, Harabayashi R, Harada R, Yamagami Y, Yumoto R, Takano M.

Biochem Biophys Res Commun. 2018 Feb 26;497(1):457-463. doi: 10.1016/j.bbrc.2018.02.111. Epub 2018 Feb 13.

PMID:
29448106
12.

P-gp modulating effect of Azadirachta indica extract in multidrug-resistant cancer cell lines.

Kawami M, Yamada Y, Issarachot O, Junyaprasert VB, Yumoto R, Takano M.

Pharmazie. 2018 Feb 1;73(2):104-109. doi: 10.1691/ph.2018.7116.

PMID:
29442013
13.

Effect of Curcuma comosa extracts on the functions of peptide transporter and P-glycoprotein in intestinal epithelial cells.

Kawami M, Yamada Y, Toshimori F, Issarachot O, Junyaprasert VB, Yumoto R, Takano M.

Pharmazie. 2017 Feb 1;72(2):123-127. doi: 10.1691/ph.2017.6147.

PMID:
29441866
14.

Nicotine transport in lung and non-lung epithelial cells.

Takano M, Kamei H, Nagahiro M, Kawami M, Yumoto R.

Life Sci. 2017 Nov 1;188:76-82. doi: 10.1016/j.lfs.2017.08.030. Epub 2017 Aug 31.

PMID:
28866099
15.

Effect of COA-Cl on transforming growth factor-β1-induced epithelial-mesenchymal transition in RLE/Abca3 cells.

Kawami M, Deguchi J, Yumoto R, Sakakibara N, Tsukamoto I, Konishi R, Takano M.

Drug Metab Pharmacokinet. 2017 Aug;32(4):224-227. doi: 10.1016/j.dmpk.2017.05.001. Epub 2017 May 17.

PMID:
28736185
16.

Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs.

Ehrhardt C, Bäckman P, Couet W, Edwards C, Forbes B, Fridén M, Gumbleton M, Hosoya KI, Kato Y, Nakanishi T, Takano M, Terasaki T, Yumoto R.

J Pharm Sci. 2017 Sep;106(9):2234-2244. doi: 10.1016/j.xphs.2017.04.011. Epub 2017 Apr 15. Review.

PMID:
28416418
17.

Role of miR-34a in TGF-β1- and Drug-Induced Epithelial-Mesenchymal Transition in Alveolar Type II Epithelial Cells.

Takano M, Nekomoto C, Kawami M, Yumoto R.

J Pharm Sci. 2017 Sep;106(9):2868-2872. doi: 10.1016/j.xphs.2017.04.002. Epub 2017 Apr 10.

PMID:
28408209
18.

Planar PtPd3 Complexes Stabilized by Three Bridging Silylene Ligands.

Tanabe M, Yumoto R, Yamada T, Fukuta T, Hoshino T, Osakada K, Tanase T.

Chemistry. 2017 Jan 26;23(6):1386-1392. doi: 10.1002/chem.201604502. Epub 2016 Dec 27.

PMID:
27864855
19.

Effect of cigarette smoke extract on P-glycoprotein function in primary cultured and newly developed alveolar epithelial cells.

Takano M, Naka R, Sasaki Y, Nishimoto S, Yumoto R.

Drug Metab Pharmacokinet. 2016 Dec;31(6):417-424. doi: 10.1016/j.dmpk.2016.08.006. Epub 2016 Aug 31.

PMID:
27836711
20.

Methotrexate-Induced Epithelial-Mesenchymal Transition in the Alveolar Epithelial Cell Line A549.

Kawami M, Harabayashi R, Miyamoto M, Harada R, Yumoto R, Takano M.

Lung. 2016 Dec;194(6):923-930. Epub 2016 Sep 7.

PMID:
27604426
21.

Transport Mechanism of Nicotine in Primary Cultured Alveolar Epithelial Cells.

Takano M, Nagahiro M, Yumoto R.

J Pharm Sci. 2016 Feb;105(2):982-988. doi: 10.1002/jps.24627. Epub 2016 Jan 12.

PMID:
26343920
22.

Methotrexate influx via folate transporters into alveolar epithelial cell line A549.

Kawami M, Miyamoto M, Yumoto R, Takano M.

Drug Metab Pharmacokinet. 2015 Aug;30(4):276-81. doi: 10.1016/j.dmpk.2015.04.005. Epub 2015 May 16.

PMID:
26190800
23.

Functional Expression of PEPT2 in the Human Distal Lung Epithelial Cell Line NCl-H441.

Takano M, Sugimoto N, Ehrhardt C, Yumoto R.

Pharm Res. 2015 Dec;32(12):3916-26. doi: 10.1007/s11095-015-1751-x. Epub 2015 Jul 14.

PMID:
26168863
24.

Modulation of P-glycoprotein function and multidrug resistance in cancer cells by Thai plant extracts.

Takano M, Kakizoe S, Kawami M, Nagai J, Patanasethnont D, Sripanidkulchai B, Yumoto R.

Pharmazie. 2014 Nov;69(11):823-8.

PMID:
25985578
25.

Analysis of TGF-β1- and drug-induced epithelial-mesenchymal transition in cultured alveolar epithelial cell line RLE/Abca3.

Takano M, Yamamoto C, Yamaguchi K, Kawami M, Yumoto R.

Drug Metab Pharmacokinet. 2015 Feb;30(1):111-8. doi: 10.1016/j.dmpk.2014.10.007. Epub 2014 Nov 4.

PMID:
25760538
26.

Cisplatin resistance in human lung cancer cells is linked with dysregulation of cell cycle associated proteins.

Horibe S, Matsuda A, Tanahashi T, Inoue J, Kawauchi S, Mizuno S, Ueno M, Takahashi K, Maeda Y, Maegouchi T, Murakami Y, Yumoto R, Nagai J, Takano M.

Life Sci. 2015 Mar 1;124:31-40. doi: 10.1016/j.lfs.2015.01.011. Epub 2015 Jan 24.

PMID:
25625243
27.

Receptor-mediated endocytosis of macromolecules and strategy to enhance their transport in alveolar epithelial cells.

Takano M, Kawami M, Aoki A, Yumoto R.

Expert Opin Drug Deliv. 2015 May;12(5):813-25. doi: 10.1517/17425247.2015.992778. Epub 2014 Dec 12. Review.

PMID:
25496474
28.

Fatty acid-bearing albumin but not fatty acid-depleted albumin induces HIF-1 activation in human renal proximal tubular epithelial cell line HK-2.

Nagai J, Yamamoto A, Katagiri Y, Yumoto R, Takano M.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):476-81. doi: 10.1016/j.bbrc.2014.05.146. Epub 2014 Jun 9.

PMID:
24924632
29.

Characterization of protamine uptake by opossum kidney epithelial cells.

Nagai J, Komeda T, Katagiri Y, Yumoto R, Takano M.

Biol Pharm Bull. 2013;36(12):1942-9.

30.

Expression and function of PEPT2 during transdifferentiation of alveolar epithelial cells.

Takano M, Horiuchi T, Sasaki Y, Kato Y, Nagai J, Yumoto R.

Life Sci. 2013 Oct 17;93(17):630-6. doi: 10.1016/j.lfs.2013.08.008. Epub 2013 Aug 27.

PMID:
23988852
31.

Enhancing effect of poly(amino acid)s on albumin uptake in human lung epithelial A549 cells.

Yumoto R, Suzuka S, Nishimoto S, Nagai J, Takano M.

Drug Metab Pharmacokinet. 2013;28(6):497-503. Epub 2013 May 28.

32.

Albumin overload induces expression of hypoxia-inducible factor 1α and its target genes in HK-2 human renal proximal tubular cell line.

Nagai J, Yamamoto A, Yumoto R, Takano M.

Biochem Biophys Res Commun. 2013 May 10;434(3):670-5. doi: 10.1016/j.bbrc.2013.03.140. Epub 2013 Apr 12.

PMID:
23587905
33.

Effect of protamine on the accumulation of gentamicin in opossum kidney epithelial cells.

Nagai J, Komeda T, Yumoto R, Takano M.

J Pharm Pharmacol. 2013 Mar;65(3):441-6. doi: 10.1111/jphp.12005. Epub 2012 Nov 15.

PMID:
23356853
34.

Effect of cigarette smoke extract on insulin transport in alveolar epithelial cell line A549.

Takano M, Horiuchi T, Nagai J, Yumoto R.

Lung. 2012 Dec;190(6):651-9. doi: 10.1007/s00408-012-9413-9. Epub 2012 Sep 8.

PMID:
22960792
35.

Flow cytometry analysis of cancer cell death induced by the extract of Thai plant Ellipeiopsis cherrevensis.

Yumoto R, Kakizoe S, Nagai J, Patanasethanont D, Sripanidkulchai BO, Takano M.

Drug Metab Pharmacokinet. 2013;28(2):159-63. Epub 2012 Jul 31.

36.

Enhancement effect of poly(amino acid)s on insulin uptake in alveolar epithelial cells.

Oda K, Yumoto R, Nagai J, Katayama H, Takano M.

Drug Metab Pharmacokinet. 2012;27(6):570-8. Epub 2012 Apr 17.

37.

Gadolinium modulates gentamicin uptake via an endocytosis-independent pathway in HK-2 human renal proximal tubular cell line.

Sawada T, Nagai J, Okada Y, Yumoto R, Takano M.

Eur J Pharmacol. 2012 Jun 5;684(1-3):146-53. doi: 10.1016/j.ejphar.2012.03.030. Epub 2012 Mar 29.

PMID:
22484335
38.

Reaction of an alkyne with dinickel-diphenylsilyl complexes. An emissive disilane formed via the consecutive Si-C and Si-Si bond-making processes.

Tanabe M, Yumoto R, Osakada K.

Chem Commun (Camb). 2012 Feb 18;48(15):2125-7. doi: 10.1039/c2cc16063c. Epub 2012 Jan 13.

PMID:
22241522
39.

Endocytic uptake of FITC-albumin by human alveolar epithelial cell line A549.

Yumoto R, Suzuka S, Oda K, Nagai J, Takano M.

Drug Metab Pharmacokinet. 2012;27(3):336-43. Epub 2012 Jan 3.

40.

Nanoparticulation of probucol, a poorly water-soluble drug, using a novel wet-milling process to improve in vitro dissolution and in vivo oral absorption.

Tanaka Y, Inkyo M, Yumoto R, Nagai J, Takano M, Nagata S.

Drug Dev Ind Pharm. 2012 Aug;38(8):1015-23. doi: 10.3109/03639045.2011.637051. Epub 2011 Nov 26.

PMID:
22118063
41.

Mechanism underlying insulin uptake in alveolar epithelial cell line RLE-6TN.

Oda K, Yumoto R, Nagai J, Katayama H, Takano M.

Eur J Pharmacol. 2011 Dec 15;672(1-3):62-9. doi: 10.1016/j.ejphar.2011.10.003. Epub 2011 Oct 10.

PMID:
22004610
42.

Megalin/cubilin-mediated uptake of FITC-labeled IgG by OK kidney epithelial cells.

Nagai J, Sato K, Yumoto R, Takano M.

Drug Metab Pharmacokinet. 2011;26(5):474-85. Epub 2011 Jun 28.

43.

Role of phosphatidylserine binding in tissue distribution of amine-containing basic compounds.

Murakami T, Yumoto R.

Expert Opin Drug Metab Toxicol. 2011 Mar;7(3):353-64. doi: 10.1517/17425255.2011.548805. Review.

PMID:
21332386
44.

Accumulation and photodynamic activity of chlorin e6 in cisplatin-resistant human lung cancer cells.

Horibe S, Nagai J, Yumoto R, Tawa R, Takano M.

J Pharm Sci. 2011 Jul;100(7):3010-7. doi: 10.1002/jps.22501. Epub 2011 Jan 27.

PMID:
21274848
45.

Human erythrocyte nucleoside transporter ENT1 functions at ice-cold temperatures.

Takano M, Kimura E, Suzuki S, Nagai J, Yumoto R.

Drug Metab Pharmacokinet. 2010;25(4):351-60.

46.

Effect of Thai plant extracts on P-glycoprotein function and viability in paclitaxel-resistant HepG2 cells.

Kawami M, Yumoto R, Nagai J, Junyaprasert VB, Soonthornchareonnon N, Patanasethanont D, Sripanidkulchai BO, Takano M.

Drug Metab Pharmacokinet. 2010;25(2):155-62.

47.

Function and expression of ATP-binding cassette transporters in cultured human Y79 retinoblastoma cells.

Ishikawa Y, Nagai J, Okada Y, Sato K, Yumoto R, Takano M.

Biol Pharm Bull. 2010;33(3):504-11.

48.

Paclitaxel-resistance conferred by altered expression of efflux and influx transporters for paclitaxel in the human hepatoma cell line, HepG2.

Takano M, Otani Y, Tanda M, Kawami M, Nagai J, Yumoto R.

Drug Metab Pharmacokinet. 2009;24(5):418-27.

49.

Nanoparticulation of poorly water soluble drugs using a wet-mill process and physicochemical properties of the nanopowders.

Tanaka Y, Inkyo M, Yumoto R, Nagai J, Takano M, Nagata S.

Chem Pharm Bull (Tokyo). 2009 Oct;57(10):1050-7.

50.

Mechanism of insulin uptake in rat alveolar type II and type I-like epithelial cells.

Ikehata M, Yumoto R, Kato Y, Nagai J, Takano M.

Biol Pharm Bull. 2009 Oct;32(10):1765-9.

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