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Items: 24

1.

Disruption of latent HIV in vivo during the clearance of actinic keratosis by ingenol mebutate.

Jiang G, Maverakis E, Cheng MY, Elsheikh MM, Deleage C, Méndez-Lagares G, Shimoda M, Yukl SA, Hartigan-O'Connor DJ, Thompson GR 3rd, Estes JD, Wong JK, Dandekar S.

JCI Insight. 2019 Apr 4;4(7). pii: 126027. doi: 10.1172/jci.insight.126027. eCollection 2019 Apr 4.

2.

Characterization of the HIV-1 transcription profile after romidepsin administration in ART-suppressed individuals.

Moron-Lopez S, Kim P, Søgaard OS, Tolstrup M, Wong JK, Yukl SA.

AIDS. 2019 Mar 1;33(3):425-431. doi: 10.1097/QAD.0000000000002083.

PMID:
30531314
3.

Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency.

Telwatte S, Lee S, Somsouk M, Hatano H, Baker C, Kaiser P, Kim P, Chen TH, Milush J, Hunt PW, Deeks SG, Wong JK, Yukl SA.

PLoS Pathog. 2018 Nov 15;14(11):e1007357. doi: 10.1371/journal.ppat.1007357. eCollection 2018 Nov.

4.

HIV latency in isolated patient CD4+ T cells may be due to blocks in HIV transcriptional elongation, completion, and splicing.

Yukl SA, Kaiser P, Kim P, Telwatte S, Joshi SK, Vu M, Lampiris H, Wong JK.

Sci Transl Med. 2018 Feb 28;10(430). pii: eaap9927. doi: 10.1126/scitranslmed.aap9927.

5.

HIV latency is reversed by ACSS2-driven histone crotonylation.

Jiang G, Nguyen D, Archin NM, Yukl SA, Méndez-Lagares G, Tang Y, Elsheikh MM, Thompson GR 3rd, Hartigan-O'Connor DJ, Margolis DM, Wong JK, Dandekar S.

J Clin Invest. 2018 Mar 1;128(3):1190-1198. doi: 10.1172/JCI98071. Epub 2018 Feb 19.

6.

HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study.

Henrich TJ, Hatano H, Bacon O, Hogan LE, Rutishauser R, Hill A, Kearney MF, Anderson EM, Buchbinder SP, Cohen SE, Abdel-Mohsen M, Pohlmeyer CW, Fromentin R, Hoh R, Liu AY, McCune JM, Spindler J, Metcalf-Pate K, Hobbs KS, Thanh C, Gibson EA, Kuritzkes DR, Siliciano RF, Price RW, Richman DD, Chomont N, Siliciano JD, Mellors JW, Yukl SA, Blankson JN, Liegler T, Deeks SG.

PLoS Med. 2017 Nov 7;14(11):e1002417. doi: 10.1371/journal.pmed.1002417. eCollection 2017 Nov.

7.

A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals.

Cockerham LR, Yukl SA, Harvill K, Somsouk M, Joshi SK, Sinclair E, Liegler T, Hoh R, Lyons S, Hunt PW, Rupert A, Sereti I, Morcock DR, Rhodes A, Emson C, Hellerstein MK, Estes JD, Lewin S, Deeks SG, Hatano H.

Pathog Immun. 2017;2(3):310-334. doi: 10.20411/pai.v2i3.207. Epub 2017 Aug 2.

8.

Assays for precise quantification of total (including short) and elongated HIV-1 transcripts.

Kaiser P, Joshi SK, Kim P, Li P, Liu H, Rice AP, Wong JK, Yukl SA.

J Virol Methods. 2017 Apr;242:1-8. doi: 10.1016/j.jviromet.2016.12.017. Epub 2016 Dec 27.

9.

Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy.

Lee SA, Bacchetti P, Chomont N, Fromentin R, Lewin SR, O'Doherty U, Palmer S, Richman DD, Siliciano JD, Yukl SA, Deeks SG, Burbelo PD.

PLoS One. 2016 Aug 2;11(8):e0160192. doi: 10.1371/journal.pone.0160192. eCollection 2016.

10.

Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation.

Li P, Kaiser P, Lampiris HW, Kim P, Yukl SA, Havlir DV, Greene WC, Wong JK.

Nat Med. 2016 Jul;22(7):807-11. doi: 10.1038/nm.4124. Epub 2016 Jun 13.

11.

Tissue reservoirs of HIV.

Wong JK, Yukl SA.

Curr Opin HIV AIDS. 2016 Jul;11(4):362-70. doi: 10.1097/COH.0000000000000293. Review.

12.

Site-specific differences in T cell frequencies and phenotypes in the blood and gut of HIV-uninfected and ART-treated HIV+ adults.

Yukl SA, Shergill AK, Girling V, Li Q, Killian M, Epling L, Li P, Kaiser P, Haase A, Havlir DV, McQuaid K, Sinclair E, Wong JK.

PLoS One. 2015 Mar 26;10(3):e0121290. doi: 10.1371/journal.pone.0121290. eCollection 2015.

13.

CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells.

Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG.

PLoS One. 2014 Oct 23;9(10):e110731. doi: 10.1371/journal.pone.0110731. eCollection 2014.

14.

Advantages of using the QIAshredder instead of restriction digestion to prepare DNA for droplet digital PCR.

Yukl SA, Kaiser P, Kim P, Li P, Wong JK.

Biotechniques. 2014 Apr 1;56(4):194-6. doi: 10.2144/000114159. eCollection 2014.

15.

A comparison of methods for measuring rectal HIV levels suggests that HIV DNA resides in cells other than CD4+ T cells, including myeloid cells.

Yukl SA, Sinclair E, Somsouk M, Hunt PW, Epling L, Killian M, Girling V, Li P, Havlir DV, Deeks SG, Wong JK, Hatano H.

AIDS. 2014 Jan 28;28(3):439-42. doi: 10.1097/QAD.0000000000000166.

16.

Comparison of HIV DNA and RNA in gut-associated lymphoid tissue of HIV-infected controllers and noncontrollers.

Hatano H, Somsouk M, Sinclair E, Harvill K, Gilman L, Cohen M, Hoh R, Hunt PW, Martin JN, Wong JK, Deeks SG, Yukl SA.

AIDS. 2013 Sep 10;27(14):2255-60. doi: 10.1097/QAD.0b013e328362692f.

17.

Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers.

Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, Tracy RP, Busch MP, O'Doherty U, Shacklett BL, Wong JK, Deeks SG.

PLoS Pathog. 2013;9(10):e1003691. doi: 10.1371/journal.ppat.1003691. Epub 2013 Oct 10.

18.

Discordance between peripheral and colonic markers of inflammation during suppressive ART.

Dunham RM, Vujkovic-Cvijin I, Yukl SA, Broadhurst MJ, Loke P, Albright RG, Wong JK, Lederman MM, Somsouk M, Hunt PW, Martin JN, Deeks SG, McCune JM.

J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):133-41. doi: 10.1097/01.qai.0000437172.08127.0b.

19.

The distribution of HIV DNA and RNA in cell subsets differs in gut and blood of HIV-positive patients on ART: implications for viral persistence.

Yukl SA, Shergill AK, Ho T, Killian M, Girling V, Epling L, Li P, Wong LK, Crouch P, Deeks SG, Havlir DV, McQuaid K, Sinclair E, Wong JK.

J Infect Dis. 2013 Oct 15;208(8):1212-20. doi: 10.1093/infdis/jit308. Epub 2013 Jul 12.

20.

Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient.

Yukl SA, Boritz E, Busch M, Bentsen C, Chun TW, Douek D, Eisele E, Haase A, Ho YC, Hütter G, Justement JS, Keating S, Lee TH, Li P, Murray D, Palmer S, Pilcher C, Pillai S, Price RW, Rothenberger M, Schacker T, Siliciano J, Siliciano R, Sinclair E, Strain M, Wong J, Richman D, Deeks SG.

PLoS Pathog. 2013;9(5):e1003347. doi: 10.1371/journal.ppat.1003347. Epub 2013 May 9.

21.

Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies.

Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, Bosch RJ, Lai J, Chioma S, Emad F, Abdel-Mohsen M, Hoh R, Hecht F, Hunt P, Somsouk M, Wong J, Johnston R, Siliciano RF, Richman DD, O'Doherty U, Palmer S, Deeks SG, Siliciano JD.

PLoS Pathog. 2013 Feb;9(2):e1003174. doi: 10.1371/journal.ppat.1003174. Epub 2013 Feb 14.

22.

Modification of the Abbott RealTime assay for detection of HIV-1 plasma RNA viral loads less than one copy per milliliter.

Yukl SA, Li P, Fujimoto K, Lampiris H, Lu CM, Hare CB, Deeks SG, Liegler T, Pandori M, Havlir DV, Wong JK.

J Virol Methods. 2011 Aug;175(2):261-5. doi: 10.1016/j.jviromet.2011.04.015. Epub 2011 Apr 22.

23.

Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy.

Yukl SA, Gianella S, Sinclair E, Epling L, Li Q, Duan L, Choi AL, Girling V, Ho T, Li P, Fujimoto K, Lampiris H, Hare CB, Pandori M, Haase AT, Günthard HF, Fischer M, Shergill AK, McQuaid K, Havlir DV, Wong JK.

J Infect Dis. 2010 Nov 15;202(10):1553-61. doi: 10.1086/656722. Epub 2010 Oct 12.

24.

Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy.

Yukl SA, Shergill AK, McQuaid K, Gianella S, Lampiris H, Hare CB, Pandori M, Sinclair E, Günthard HF, Fischer M, Wong JK, Havlir DV.

AIDS. 2010 Oct 23;24(16):2451-60. doi: 10.1097/QAD.0b013e32833ef7bb.

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