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Items: 1 to 50 of 51

1.

Identification of Novel Anti-Liver Cancer Small Molecules with Better Therapeutic Index than Sorafenib via Zebrafish Drug Screening Platform.

Lin HS, Huang YL, Wang YS, Hsiao E, Hsu TA, Shiao HY, Jiaang WT, Sampurna BP, Lin KH, Wu MS, Lai GM, Yuh CH.

Cancers (Basel). 2019 May 28;11(6). pii: E739. doi: 10.3390/cancers11060739.

2.

Cytoplasmic LIF reprograms invasive mode to enhance NPC dissemination through modulating YAP1-FAK/PXN signaling.

Liu SC, Hsu T, Chang YS, Chung AK, Jiang SS, OuYang CN, Yuh CH, Hsueh C, Liu YP, Tsang NM.

Nat Commun. 2018 Nov 30;9(1):5105. doi: 10.1038/s41467-018-07660-6.

3.

Ribose-5-phosphate isomerase A overexpression promotes liver cancer development in transgenic zebrafish via activation of ERK and β-catenin pathways.

Chou YT, Chen LY, Tsai SL, Tu HC, Lu JW, Ciou SC, Wang HD, Yuh CH.

Carcinogenesis. 2019 May 14;40(3):461-473. doi: 10.1093/carcin/bgy155.

4.

Radiation-Sensitive Dendrimer-Based Drug Delivery System.

Wu SY, Chou HY, Yuh CH, Mekuria SL, Kao YC, Tsai HC.

Adv Sci (Weinh). 2017 Dec 5;5(2):1700339. doi: 10.1002/advs.201700339. eCollection 2018 Feb.

5.

Up-regulation of golgi α-mannosidase IA and down-regulation of golgi α-mannosidase IC activates unfolded protein response during hepatocarcinogenesis.

Tu HC, Hsiao YC, Yang WY, Tsai SL, Lin HK, Liao CY, Lu JW, Chou YT, Wang HD, Yuh CH.

Hepatol Commun. 2017 Apr 19;1(3):230-247. doi: 10.1002/hep4.1032. eCollection 2017 May.

6.

Identification of a noncanonical function for ribose-5-phosphate isomerase A promotes colorectal cancer formation by stabilizing and activating β-catenin via a novel C-terminal domain.

Chou YT, Jiang JK, Yang MH, Lu JW, Lin HK, Wang HD, Yuh CH.

PLoS Biol. 2018 Jan 16;16(1):e2003714. doi: 10.1371/journal.pbio.2003714. eCollection 2018 Jan.

7.

CpG-oligodeoxynucleotides developed for grouper toll-like receptor (TLR) 21s effectively activate mouse and human TLR9s mediated immune responses.

Yeh DW, Lai CY, Liu YL, Lu CH, Tseng PH, Yuh CH, Yu GY, Liu SJ, Leng CH, Chuang TH.

Sci Rep. 2017 Dec 11;7(1):17297. doi: 10.1038/s41598-017-17609-2.

8.

Epigenetic regulation of NOTCH1 and NOTCH3 by KMT2A inhibits glioma proliferation.

Huang YC, Lin SJ, Shih HY, Chou CH, Chu HH, Chiu CC, Yuh CH, Yeh TH, Cheng YC.

Oncotarget. 2017 Jun 27;8(38):63110-63120. doi: 10.18632/oncotarget.18668. eCollection 2017 Sep 8.

9.

NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish.

Yang CH, Yeh YJ, Wang JY, Liu YW, Chen YL, Cheng HW, Cheng CM, Chuang YJ, Yuh CH, Chen YR.

Sci Rep. 2017 Jul 12;7(1):5241. doi: 10.1038/s41598-017-05584-7.

10.

Lymphotoxin-β Interacts with Methylated EGFR to Mediate Acquired Resistance to Cetuximab in Head and Neck Cancer.

Hsu DS, Hwang WL, Yuh CH, Chu CH, Ho YH, Chen PB, Lin HS, Lin HK, Wu SP, Lin CY, Hsu WH, Lan HY, Wang HJ, Tai SK, Hung MC, Yang MH.

Clin Cancer Res. 2017 Aug 1;23(15):4388-4401. doi: 10.1158/1078-0432.CCR-16-1955. Epub 2017 Feb 14.

11.

A Sketch of the Taiwan Zebrafish Core Facility.

You MS, Jiang YJ, Yuh CH, Wang CM, Tang CH, Chuang YJ, Lin BH, Wu JL, Hwang SP.

Zebrafish. 2016 Jul;13 Suppl 1:S24-9. doi: 10.1089/zeb.2015.1208. Epub 2016 Jun 6.

PMID:
27267235
12.

HMDB and 5-AzadC Combination Reverses Tumor Suppressor CCAAT/Enhancer-Binding Protein Delta to Strengthen the Death of Liver Cancer Cells.

Li CF, Tsai HH, Ko CY, Pan YC, Yen CJ, Lai HY, Yuh CH, Wu WC, Wang JM.

Mol Cancer Ther. 2015 Nov;14(11):2623-33. doi: 10.1158/1535-7163.MCT-15-0025. Epub 2015 Sep 10.

13.

Ribose-5-phosphate isomerase A regulates hepatocarcinogenesis via PP2A and ERK signaling.

Ciou SC, Chou YT, Liu YL, Nieh YC, Lu JW, Huang SF, Chou YT, Cheng LH, Lo JF, Chen MJ, Yang MC, Yuh CH, Wang HD.

Int J Cancer. 2015 Jul 1;137(1):104-15. doi: 10.1002/ijc.29361. Epub 2014 Dec 12.

14.

Zebrafish WNK lysine deficient protein kinase 1 (wnk1) affects angiogenesis associated with VEGF signaling.

Lai JG, Tsai SM, Tu HC, Chen WC, Kou FJ, Lu JW, Wang HD, Huang CL, Yuh CH.

PLoS One. 2014 Aug 29;9(8):e106129. doi: 10.1371/journal.pone.0106129. eCollection 2014.

15.

Diacylglycerol lipase regulates lifespan and oxidative stress response by inversely modulating TOR signaling in Drosophila and C. elegans.

Lin YH, Chen YC, Kao TY, Lin YC, Hsu TE, Wu YC, Ja WW, Brummel TJ, Kapahi P, Yuh CH, Yu LK, Lin ZH, You RJ, Jhong YT, Wang HD.

Aging Cell. 2014 Aug;13(4):755-64. doi: 10.1111/acel.12232. Epub 2014 May 30.

16.

Identification of transforming hepatitis B virus S gene nonsense mutations derived from freely replicative viruses in hepatocellular carcinoma.

Huang SF, Chen YT, Lee WC, Chang IC, Chiu YT, Chang Y, Tu HC, Yuh CH, Matsuura I, Shih LY, Lai MW, Wu HD, Chen MF, Yeh CT.

PLoS One. 2014 Feb 24;9(2):e89753. doi: 10.1371/journal.pone.0089753. eCollection 2014.

17.

Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway.

Lu JW, Liao CY, Yang WY, Lin YM, Jin SL, Wang HD, Yuh CH.

PLoS One. 2014 Jan 8;9(1):e85318. doi: 10.1371/journal.pone.0085318. eCollection 2014.

18.

Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish.

Yeh DW, Liu YL, Lo YC, Yuh CH, Yu GY, Lo JF, Luo Y, Xiang R, Chuang TH.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20711-6. doi: 10.1073/pnas.1305273110. Epub 2013 Nov 26.

19.

Liver-specific expressions of HBx and src in the p53 mutant trigger hepatocarcinogenesis in zebrafish.

Lu JW, Yang WY, Tsai SM, Lin YM, Chang PH, Chen JR, Wang HD, Wu JL, Jin SL, Yuh CH.

PLoS One. 2013 Oct 9;8(10):e76951. doi: 10.1371/journal.pone.0076951. eCollection 2013.

20.

Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish.

Lu JW, Yang WY, Lin YM, Jin SL, Yuh CH.

Acta Histochem. 2013 Sep;115(7):728-39. doi: 10.1016/j.acthis.2013.02.012. Epub 2013 Mar 15.

PMID:
23499292
21.

Escherichia coli noncoding RNAs can affect gene expression and physiology of Caenorhabditis elegans.

Liu H, Wang X, Wang HD, Wu J, Ren J, Meng L, Wu Q, Dong H, Wu J, Kao TY, Ge Q, Wu ZX, Yuh CH, Shan G.

Nat Commun. 2012;3:1073. doi: 10.1038/ncomms2071.

22.

Reduced neuronal expression of ribose-5-phosphate isomerase enhances tolerance to oxidative stress, extends lifespan, and attenuates polyglutamine toxicity in Drosophila.

Wang CT, Chen YC, Wang YY, Huang MH, Yen TL, Li H, Liang CJ, Sang TK, Ciou SC, Yuh CH, Wang CY, Brummel TJ, Wang HD.

Aging Cell. 2012 Feb;11(1):93-103. doi: 10.1111/j.1474-9726.2011.00762.x. Epub 2011 Nov 28.

23.

Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model.

Lu JW, Hsia Y, Yang WY, Lin YI, Li CC, Tsai TF, Chang KW, Shieh GS, Tsai SF, Wang HD, Yuh CH.

Carcinogenesis. 2012 Jan;33(1):209-19. doi: 10.1093/carcin/bgr224. Epub 2011 Oct 21.

PMID:
22021908
24.

An evolutionarily conserved kernel of gata5, gata6, otx2 and prdm1a operates in the formation of endoderm in zebrafish.

Tseng WF, Jang TH, Huang CB, Yuh CH.

Dev Biol. 2011 Sep 15;357(2):541-57. doi: 10.1016/j.ydbio.2011.06.040. Epub 2011 Jul 1.

25.

Liver development and cancer formation in zebrafish.

Lu JW, Hsia Y, Tu HC, Hsiao YC, Yang WY, Wang HD, Yuh CH.

Birth Defects Res C Embryo Today. 2011 Jun;93(2):157-72. doi: 10.1002/bdrc.20205. Review.

PMID:
21671355
26.

Integration of CNS survival and differentiation by HIF2α.

Ko CY, Tsai MY, Tseng WF, Cheng CH, Huang CR, Wu JS, Chung HY, Hsieh CS, Sun CK, Hwang SP, Yuh CH, Huang CJ, Pai TW, Tzou WS, Hu CH.

Cell Death Differ. 2011 Nov;18(11):1757-70. doi: 10.1038/cdd.2011.44. Epub 2011 May 6.

27.

Complexity of cis-regulatory organization of six3a during forebrain and eye development in zebrafish.

Chao CH, Wang HD, Yuh CH.

BMC Dev Biol. 2010 Mar 26;10:35. doi: 10.1186/1471-213X-10-35.

28.

Nestin is essential for zebrafish brain and eye development through control of progenitor cell apoptosis.

Chen HL, Yuh CH, Wu KK.

PLoS One. 2010 Feb 19;5(2):e9318. doi: 10.1371/journal.pone.0009318.

29.

Reduced expression of alpha-1,2-mannosidase I extends lifespan in Drosophila melanogaster and Caenorhabditis elegans.

Liu YL, Lu WC, Brummel TJ, Yuh CH, Lin PT, Kao TY, Li FY, Liao PC, Benzer S, Wang HD.

Aging Cell. 2009 Aug;8(4):370-9. doi: 10.1111/j.1474-9726.2009.00471.x. Epub 2009 Mar 16.

30.

Functional analysis of the evolutionarily conserved cis-regulatory elements on the sox17 gene in zebrafish.

Chan TM, Chao CH, Wang HD, Yu YJ, Yuh CH.

Dev Biol. 2009 Feb 15;326(2):456-70. doi: 10.1016/j.ydbio.2008.11.010. Epub 2008 Nov 24.

31.

Developmental gene regulatory networks in the zebrafish embryo.

Chan TM, Longabaugh W, Bolouri H, Chen HL, Tseng WF, Chao CH, Jang TH, Lin YI, Hung SC, Wang HD, Yuh CH.

Biochim Biophys Acta. 2009 Apr;1789(4):279-98. doi: 10.1016/j.bbagrm.2008.09.005. Epub 2008 Oct 8. Review.

PMID:
18992377
32.

The effect of neuronal expression of heat shock proteins 26 and 27 on lifespan, neurodegeneration, and apoptosis in Drosophila.

Liao PC, Lin HY, Yuh CH, Yu LK, Wang HD.

Biochem Biophys Res Commun. 2008 Nov 28;376(4):637-41. doi: 10.1016/j.bbrc.2008.08.161. Epub 2008 Sep 15.

PMID:
18796296
33.

Brn1/2/4, the predicted midgut regulator of the endo16 gene of the sea urchin embryo.

Yuh CH, Dorman ER, Davidson EH.

Dev Biol. 2005 May 15;281(2):286-98.

34.

Identification of sequence-specific DNA binding proteins.

Coffman JA, Yuh CH.

Methods Cell Biol. 2004;74:653-75. Review. No abstract available.

PMID:
15575625
35.

An otx cis-regulatory module: a key node in the sea urchin endomesoderm gene regulatory network.

Yuh CH, Dorman ER, Howard ML, Davidson EH.

Dev Biol. 2004 May 15;269(2):536-51.

36.

A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo.

Davidson EH, Rast JP, Oliveri P, Ransick A, Calestani C, Yuh CH, Minokawa T, Amore G, Hinman V, Arenas-Mena C, Otim O, Brown CT, Livi CB, Lee PY, Revilla R, Schilstra MJ, Clarke PJ, Rust AG, Pan Z, Arnone MI, Rowen L, Cameron RA, McClay DR, Hood L, Bolouri H.

Dev Biol. 2002 Jun 1;246(1):162-90.

37.

Patchy interspecific sequence similarities efficiently identify positive cis-regulatory elements in the sea urchin.

Yuh CH, Brown CT, Livi CB, Rowen L, Clarke PJ, Davidson EH.

Dev Biol. 2002 Jun 1;246(1):148-61.

38.

A genomic regulatory network for development.

Davidson EH, Rast JP, Oliveri P, Ransick A, Calestani C, Yuh CH, Minokawa T, Amore G, Hinman V, Arenas-Mena C, Otim O, Brown CT, Livi CB, Lee PY, Revilla R, Rust AG, Pan Zj, Schilstra MJ, Clarke PJ, Arnone MI, Rowen L, Cameron RA, McClay DR, Hood L, Bolouri H.

Science. 2002 Mar 1;295(5560):1669-78. Review.

PMID:
11872831
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41.

Genomic cis-regulatory logic: experimental and computational analysis of a sea urchin gene.

Yuh CH, Bolouri H, Davidson EH.

Science. 1998 Mar 20;279(5358):1896-902.

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