Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 151

1.

ALK-positive histiocytosis: an expanded clinicopathologic spectrum and frequent presence of KIF5B-ALK fusion.

Chang KTE, Tay AZE, Kuick CH, Chen H, Algar E, Taubenheim N, Campbell J, Mechinaud F, Campbell M, Super L, Chantranuwat C, Yuen ST, Chan JKC, Chow CW.

Mod Pathol. 2019 May;32(5):598-608. doi: 10.1038/s41379-018-0168-6. Epub 2018 Dec 20.

PMID:
30573850
2.

A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening.

Yan HHN, Siu HC, Law S, Ho SL, Yue SSK, Tsui WY, Chan D, Chan AS, Ma S, Lam KO, Bartfeld S, Man AHY, Lee BCH, Chan ASY, Wong JWH, Cheng PSW, Chan AKW, Zhang J, Shi J, Fan X, Kwong DLW, Mak TW, Yuen ST, Clevers H, Leung SY.

Cell Stem Cell. 2018 Dec 6;23(6):882-897.e11. doi: 10.1016/j.stem.2018.09.016. Epub 2018 Oct 18.

3.

Genomics Study of Gastric Cancer and Its Molecular Subtypes.

Yuen ST, Leung SY.

Adv Exp Med Biol. 2016;908:419-39. doi: 10.1007/978-3-319-41388-4_21. Review.

PMID:
27573784
4.

RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation.

Yan HHN, Lai JCW, Ho SL, Leung WK, Law WL, Lee JFY, Chan AKW, Tsui WY, Chan ASY, Lee BCH, Yue SSK, Man AHY, Clevers H, Yuen ST, Leung SY.

Gut. 2017 Sep;66(9):1645-1656. doi: 10.1136/gutjnl-2016-311849. Epub 2016 Jun 21.

PMID:
27329244
5.

Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.

Wang K, Yuen ST, Xu J, Lee SP, Yan HH, Shi ST, Siu HC, Deng S, Chu KM, Law S, Chan KH, Chan AS, Tsui WY, Ho SL, Chan AK, Man JL, Foglizzo V, Ng MK, Chan AS, Ching YP, Cheng GH, Xie T, Fernandez J, Li VS, Clevers H, Rejto PA, Mao M, Leung SY.

Nat Genet. 2014 Jun;46(6):573-82. doi: 10.1038/ng.2983. Epub 2014 May 11.

PMID:
24816253
6.

Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.

Thompson BA, Spurdle AB, Plazzer JP, Greenblatt MS, Akagi K, Al-Mulla F, Bapat B, Bernstein I, Capellá G, den Dunnen JT, du Sart D, Fabre A, Farrell MP, Farrington SM, Frayling IM, Frebourg T, Goldgar DE, Heinen CD, Holinski-Feder E, Kohonen-Corish M, Robinson KL, Leung SY, Martins A, Moller P, Morak M, Nystrom M, Peltomaki P, Pineda M, Qi M, Ramesar R, Rasmussen LJ, Royer-Pokora B, Scott RJ, Sijmons R, Tavtigian SV, Tops CM, Weber T, Wijnen J, Woods MO, Macrae F, Genuardi M.

Nat Genet. 2014 Feb;46(2):107-115. doi: 10.1038/ng.2854. Epub 2013 Dec 22.

7.

Altered regulation of DNA ligase IV activity by aberrant promoter DNA methylation and gene amplification in colorectal cancer.

Kuhmann C, Li C, Kloor M, Salou M, Weigel C, Schmidt CR, Ng LW, Tsui WW, Leung SY, Yuen ST, Becker N, Weichenhan D, Plass C, Schmezer P, Chan TL, Popanda O.

Hum Mol Genet. 2014 Apr 15;23(8):2043-54. doi: 10.1093/hmg/ddt599. Epub 2013 Nov 26.

PMID:
24282031
8.

Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer.

Fan B, Dachrut S, Coral H, Yuen ST, Chu KM, Law S, Zhang L, Ji J, Leung SY, Chen X.

PLoS One. 2012;7(4):e29824. doi: 10.1371/journal.pone.0029824. Epub 2012 Apr 23.

9.

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer.

Wang K, Kan J, Yuen ST, Shi ST, Chu KM, Law S, Chan TL, Kan Z, Chan AS, Tsui WY, Lee SP, Ho SL, Chan AK, Cheng GH, Roberts PC, Rejto PA, Gibson NW, Pocalyko DJ, Mao M, Xu J, Leung SY.

Nat Genet. 2011 Oct 30;43(12):1219-23. doi: 10.1038/ng.982.

PMID:
22037554
10.

Indian hedgehog regulates intestinal stem cell fate through epithelial-mesenchymal interactions during development.

Kosinski C, Stange DE, Xu C, Chan AS, Ho C, Yuen ST, Mifflin RC, Powell DW, Clevers H, Leung SY, Chen X.

Gastroenterology. 2010 Sep;139(3):893-903. doi: 10.1053/j.gastro.2010.06.014. Epub 2010 Jun 11.

11.

The effect of using a geotextile in a monolithic (evapotranspiration) alternative landfill cover on the resulting water balance.

Sun J, Yuen ST, Fourie AB.

Waste Manag. 2010 Nov;30(11):2074-83. doi: 10.1016/j.wasman.2010.05.009. Epub 2010 Jun 11.

PMID:
20541927
12.

Prognostic relevance of DNA copy number changes in colorectal cancer.

Poulogiannis G, Ichimura K, Hamoudi RA, Luo F, Leung SY, Yuen ST, Harrison DJ, Wyllie AH, Arends MJ.

J Pathol. 2010 Feb;220(3):338-47. doi: 10.1002/path.2640.

PMID:
19911421
13.

Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma.

Schetter AJ, Nguyen GH, Bowman ED, Mathé EA, Yuen ST, Hawkes JE, Croce CM, Leung SY, Harris CC.

Clin Cancer Res. 2009 Sep 15;15(18):5878-87. doi: 10.1158/1078-0432.CCR-09-0627. Epub 2009 Sep 8.

14.

IgG4-related Sclerosing disease: a potential new etiology of cutaneous pseudolymphoma.

Cheuk W, Lee KC, Chong LY, Yuen ST, Chan JK.

Am J Surg Pathol. 2009 Nov;33(11):1713-9. doi: 10.1097/PAS.0b013e3181b201de.

PMID:
19701072
15.

Serum macrophage migration-inhibitory factor as a diagnostic and prognostic biomarker for gastric cancer.

Xia HH, Yang Y, Chu KM, Gu Q, Zhang YY, He H, Wong WM, Leung SY, Yuen ST, Yuen MF, Chan AO, Wong BC.

Cancer. 2009 Dec 1;115(23):5441-9. doi: 10.1002/cncr.24609.

16.

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer.

van Haaften G, Dalgliesh GL, Davies H, Chen L, Bignell G, Greenman C, Edkins S, Hardy C, O'Meara S, Teague J, Butler A, Hinton J, Latimer C, Andrews J, Barthorpe S, Beare D, Buck G, Campbell PJ, Cole J, Forbes S, Jia M, Jones D, Kok CY, Leroy C, Lin ML, McBride DJ, Maddison M, Maquire S, McLay K, Menzies A, Mironenko T, Mulderrig L, Mudie L, Pleasance E, Shepherd R, Smith R, Stebbings L, Stephens P, Tang G, Tarpey PS, Turner R, Turrell K, Varian J, West S, Widaa S, Wray P, Collins VP, Ichimura K, Law S, Wong J, Yuen ST, Leung SY, Tonon G, DePinho RA, Tai YT, Anderson KC, Kahnoski RJ, Massie A, Khoo SK, Teh BT, Stratton MR, Futreal PA.

Nat Genet. 2009 May;41(5):521-3. doi: 10.1038/ng.349. Epub 2009 Mar 29.

17.

Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms.

Li VS, Yuen ST, Chan TL, Yan HH, Law WL, Yeung BH, Chan AS, Tsui WY, So S, Chen X, Leung SY.

Gastroenterology. 2009 Jul;137(1):176-87. doi: 10.1053/j.gastro.2009.03.005. Epub 2009 Mar 18.

PMID:
19303019
18.

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.

Ligtenberg MJ, Kuiper RP, Chan TL, Goossens M, Hebeda KM, Voorendt M, Lee TY, Bodmer D, Hoenselaar E, Hendriks-Cornelissen SJ, Tsui WY, Kong CK, Brunner HG, van Kessel AG, Yuen ST, van Krieken JH, Leung SY, Hoogerbrugge N.

Nat Genet. 2009 Jan;41(1):112-7. doi: 10.1038/ng.283. Epub 2008 Dec 21.

PMID:
19098912
19.

Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.

Suehiro Y, Wong CW, Chirieac LR, Kondo Y, Shen L, Webb CR, Chan YW, Chan AS, Chan TL, Wu TT, Rashid A, Hamanaka Y, Hinoda Y, Shannon RL, Wang X, Morris J, Issa JP, Yuen ST, Leung SY, Hamilton SR.

Clin Cancer Res. 2008 May 1;14(9):2560-9. doi: 10.1158/1078-0432.CCR-07-1802.

20.

MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma.

Schetter AJ, Leung SY, Sohn JJ, Zanetti KA, Bowman ED, Yanaihara N, Yuen ST, Chan TL, Kwong DL, Au GK, Liu CG, Calin GA, Croce CM, Harris CC.

JAMA. 2008 Jan 30;299(4):425-36. doi: 10.1001/jama.299.4.425.

21.

Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors.

Kosinski C, Li VS, Chan AS, Zhang J, Ho C, Tsui WY, Chan TL, Mifflin RC, Powell DW, Yuen ST, Leung SY, Chen X.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15418-23. Epub 2007 Sep 19.

22.

Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer.

Sääf AM, Halbleib JM, Chen X, Yuen ST, Leung SY, Nelson WJ, Brown PO.

Mol Biol Cell. 2007 Nov;18(11):4245-60. Epub 2007 Aug 15.

23.

Natural history and disease progression in Chinese chronic hepatitis B patients in immune-tolerant phase.

Hui CK, Leung N, Yuen ST, Zhang HY, Leung KW, Lu L, Cheung SK, Wong WM, Lau GK; Hong Kong Liver Fibrosis Study Group.

Hepatology. 2007 Aug;46(2):395-401.

PMID:
17628874
24.

Patterns of somatic mutation in human cancer genomes.

Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR.

Nature. 2007 Mar 8;446(7132):153-8.

25.

Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers.

Zou B, Chim CS, Zeng H, Leung SY, Yang Y, Tu SP, Lin MC, Wang J, He H, Jiang SH, Sun YW, Yu LF, Yuen ST, Kung HF, Wong BC.

Gastroenterology. 2006 Dec;131(6):1835-43. Epub 2006 Oct 1.

PMID:
17087954
26.

Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer.

Sheng JQ, Chan TL, Chan YW, Huang JS, Chen JG, Zhang MZ, Guo XL, Mu H, Chan AS, Li SR, Yuen ST, Leung SY.

Chin J Dig Dis. 2006;7(4):197-205.

PMID:
17054581
27.

Recurrent KRAS codon 146 mutations in human colorectal cancer.

Edkins S, O'Meara S, Parker A, Stevens C, Reis M, Jones S, Greenman C, Davies H, Dalgliesh G, Forbes S, Hunter C, Smith R, Stephens P, Goldstraw P, Nicholson A, Chan TL, Velculescu VE, Yuen ST, Leung SY, Stratton MR, Futreal PA.

Cancer Biol Ther. 2006 Aug;5(8):928-32. Epub 2006 Aug 1.

28.

Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer.

Chan TL, Yuen ST, Kong CK, Chan YW, Chan AS, Ng WF, Tsui WY, Lo MW, Tam WY, Li VS, Leung SY.

Nat Genet. 2006 Oct;38(10):1178-83. Epub 2006 Sep 3.

PMID:
16951683
29.

Calcified fibrous nodules in the heart: a case report.

Fan YS, Yuen ST, Leung SY.

Pathology. 2006 Jun;38(3):273-5. No abstract available.

PMID:
16753759
30.

Comprehensive analysis of 19q12 amplicon in human gastric cancers.

Leung SY, Ho C, Tu IP, Li R, So S, Chu KM, Yuen ST, Chen X.

Mod Pathol. 2006 Jun;19(6):854-63.

31.

Topological and functional discovery in a gene coexpression meta-network of gastric cancer.

Aggarwal A, Guo DL, Hoshida Y, Yuen ST, Chu KM, So S, Boussioutas A, Chen X, Bowtell D, Aburatani H, Leung SY, Tan P.

Cancer Res. 2006 Jan 1;66(1):232-41.

32.

Municipal solid waste management in the Southern Province of Sri Lanka: problems, issues and challenges.

Vidanaarachchi CK, Yuen ST, Pilapitiya S.

Waste Manag. 2006;26(8):920-30. Epub 2005 Nov 17.

PMID:
16298122
33.

Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours.

Guo DL, Zhang J, Yuen ST, Tsui WY, Chan AS, Ho C, Ji J, Leung SY, Chen X.

Carcinogenesis. 2006 Mar;27(3):454-64. Epub 2005 Nov 4.

PMID:
16272170
34.

A gene expression signature of genetic instability in colon cancer.

Giacomini CP, Leung SY, Chen X, Yuen ST, Kim YH, Bair E, Pollack JR.

Cancer Res. 2005 Oct 15;65(20):9200-5.

35.

Somatic mutations of the protein kinase gene family in human lung cancer.

Davies H, Hunter C, Smith R, Stephens P, Greenman C, Bignell G, Teague J, Butler A, Edkins S, Stevens C, Parker A, O'Meara S, Avis T, Barthorpe S, Brackenbury L, Buck G, Clements J, Cole J, Dicks E, Edwards K, Forbes S, Gorton M, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jones D, Kosmidou V, Laman R, Lugg R, Menzies A, Perry J, Petty R, Raine K, Shepherd R, Small A, Solomon H, Stephens Y, Tofts C, Varian J, Webb A, West S, Widaa S, Yates A, Brasseur F, Cooper CS, Flanagan AM, Green A, Knowles M, Leung SY, Looijenga LH, Malkowicz B, Pierotti MA, Teh BT, Yuen ST, Lakhani SR, Easton DF, Weber BL, Goldstraw P, Nicholson AG, Wooster R, Stratton MR, Futreal PA.

Cancer Res. 2005 Sep 1;65(17):7591-5.

36.

Uncertainty in biokinetic parameters on bioremediation: health risks and economic implications.

Wethasinghe C, Yuen ST, Kaluarachchi JJ, Hughes R.

Environ Int. 2006 Apr;32(3):312-23. Epub 2005 Aug 1.

PMID:
16055190
37.

The 'fifth vital sign'.

Yuen TS, Irwin MG.

Hong Kong Med J. 2005 Jun;11(3):145-6. No abstract available.

38.

BRAF and NRAS mutations are uncommon in melanomas arising in diverse internal organs.

Wong CW, Fan YS, Chan TL, Chan AS, Ho LC, Ma TK, Yuen ST, Leung SY; Cancer Genome Project.

J Clin Pathol. 2005 Jun;58(6):640-4. Review.

39.

Macrophage migration inhibitory factor expression correlates with inflammatory changes in human chronic hepatitis B infection.

Zhang HY, Nanji AA, Luk JM, Huang XR, Lo CM, Chen YX, Yuen ST, Lan HY, Lau GK.

Liver Int. 2005 Jun;25(3):571-9.

PMID:
15910495
40.

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.

Stephens P, Edkins S, Davies H, Greenman C, Cox C, Hunter C, Bignell G, Teague J, Smith R, Stevens C, O'Meara S, Parker A, Tarpey P, Avis T, Barthorpe A, Brackenbury L, Buck G, Butler A, Clements J, Cole J, Dicks E, Edwards K, Forbes S, Gorton M, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jones D, Kosmidou V, Laman R, Lugg R, Menzies A, Perry J, Petty R, Raine K, Shepherd R, Small A, Solomon H, Stephens Y, Tofts C, Varian J, Webb A, West S, Widaa S, Yates A, Brasseur F, Cooper CS, Flanagan AM, Green A, Knowles M, Leung SY, Looijenga LH, Malkowicz B, Pierotti MA, Teh B, Yuen ST, Nicholson AG, Lakhani S, Easton DF, Weber BL, Stratton MR, Futreal PA, Wooster R.

Nat Genet. 2005 Jun;37(6):590-2. Epub 2005 May 22.

PMID:
15908952
41.

Mutations of PIK3CA in gastric adenocarcinoma.

Li VS, Wong CW, Chan TL, Chan AS, Zhao W, Chu KM, So S, Chen X, Yuen ST, Leung SY.

BMC Cancer. 2005 Mar 23;5:29.

42.

CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of the stomach.

Ko S, Chu KM, Luk JM, Wong BW, Yuen ST, Leung SY, Wong J.

J Pathol. 2005 Apr;205(5):615-22.

PMID:
15732140
43.

Dopamine receptor D4 (DRD4) gene in Han Chinese children with attention-deficit/hyperactivity disorder (ADHD): increased prevalence of the 2-repeat allele.

Leung PW, Lee CC, Hung SF, Ho TP, Tang CP, Kwong SL, Leung SY, Yuen ST, Lieh-Mak F, Oosterlaan J, Grady D, Harxhi A, Ding YC, Chi HC, Flodman P, Schuck S, Spence MA, Moyzis R, Swanson J.

Am J Med Genet B Neuropsychiatr Genet. 2005 Feb 5;133B(1):54-6.

PMID:
15578612
44.

Lung cancer: intragenic ERBB2 kinase mutations in tumours.

Stephens P, Hunter C, Bignell G, Edkins S, Davies H, Teague J, Stevens C, O'Meara S, Smith R, Parker A, Barthorpe A, Blow M, Brackenbury L, Butler A, Clarke O, Cole J, Dicks E, Dike A, Drozd A, Edwards K, Forbes S, Foster R, Gray K, Greenman C, Halliday K, Hills K, Kosmidou V, Lugg R, Menzies A, Perry J, Petty R, Raine K, Ratford L, Shepherd R, Small A, Stephens Y, Tofts C, Varian J, West S, Widaa S, Yates A, Brasseur F, Cooper CS, Flanagan AM, Knowles M, Leung SY, Louis DN, Looijenga LH, Malkowicz B, Pierotti MA, Teh B, Chenevix-Trench G, Weber BL, Yuen ST, Harris G, Goldstraw P, Nicholson AG, Futreal PA, Wooster R, Stratton MR.

Nature. 2004 Sep 30;431(7008):525-6.

PMID:
15457249
45.

Diverse proteomic alterations in gastric adenocarcinoma.

He QY, Cheung YH, Leung SY, Yuen ST, Chu KM, Chiu JF.

Proteomics. 2004 Oct;4(10):3276-87.

PMID:
15378696
46.

Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles.

Subramanian S, West RB, Corless CL, Ou W, Rubin BP, Chu KM, Leung SY, Yuen ST, Zhu S, Hernandez-Boussard T, Montgomery K, Nielsen TO, Patel RM, Goldblum JR, Heinrich MC, Fletcher JA, van de Rijn M.

Oncogene. 2004 Oct 14;23(47):7780-90.

PMID:
15326474
47.

Expression profiling identifies chemokine (C-C motif) ligand 18 as an independent prognostic indicator in gastric cancer.

Leung SY, Yuen ST, Chu KM, Mathy JA, Li R, Chan AS, Law S, Wong J, Chen X, So S.

Gastroenterology. 2004 Aug;127(2):457-69.

PMID:
15300578
48.
49.

Helicobacter pylori infection is associated with increased expression of macrophage migratory inhibitory factor--by epithelial cells, T cells, and macrophages--in gastric mucosa.

Xia HH, Lam SK, Huang XR, Wong WM, Leung SY, Yuen ST, Lan HY, Wong BC.

J Infect Dis. 2004 Jul 15;190(2):293-302. Epub 2004 Jun 21.

PMID:
15216464
50.

Overexpression of LI-cadherin in gastric cancer is associated with lymph node metastasis.

Ko S, Chu KM, Luk JM, Wong BW, Yuen ST, Leung SY, Wong J.

Biochem Biophys Res Commun. 2004 Jun 25;319(2):562-8.

PMID:
15178443

Supplemental Content

Loading ...
Support Center