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CD9 blockade suppresses disease progression of high-risk pediatric B-cell precursor acute lymphoblastic leukemia and enhances chemosensitivity.

Leung KT, Zhang C, Chan KYY, Li K, Cheung JTK, Ng MHL, Zhang XB, Sit T, Lee WYW, Kang W, To KF, Yu JWS, Man TKF, Wang H, Tsang KS, Cheng FWT, Lam GKS, Chow TW, Leung AWK, Leung TF, Yuen PMP, Ng PC, Li CK.

Leukemia. 2019 Oct 17. doi: 10.1038/s41375-019-0593-7. [Epub ahead of print]


Improved Mitochondrial Metabolism and Reduced Inflammation Following Attenuation of Murine Lupus With Coenzyme Q10 Analog Idebenone.

Blanco LP, Pedersen HL, Wang X, Lightfoot YL, Seto N, Carmona-Rivera C, Yu ZX, Hoffmann V, Yuen PST, Kaplan MJ.

Arthritis Rheumatol. 2019 Sep 30. doi: 10.1002/art.41128. [Epub ahead of print]


Insight into hepatitis B prevalence and risk factors among Vietnamese Americans: a cross-sectional analysis of data from a community-based screening program.

Lee AW, Jacobs W, Chan E, Nguyen B, Hua DN, Ho JN, Yuen P, Van Nguyen T.

BMJ Open. 2019 Aug 26;9(8):e029616. doi: 10.1136/bmjopen-2019-029616.


Circadian variation in the release of small extracellular vesicles can be normalized by vesicle number or TSG101.

Koritzinsky EH, Street JM, Chari RR, Glispie DM, Bellomo TR, Aponte AM, Star RA, Yuen PST.

Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1098-F1110. doi: 10.1152/ajprenal.00568.2017. Epub 2019 Aug 7.


Nursing Home Facility-Initiated Involuntary Discharge.

Lepore MJ, Yuen PK, Zepeda S.

J Gerontol Nurs. 2019 Aug 1;45(8):23-31. doi: 10.3928/00989134-20190709-03.


Self-aligning Tetris-Like (TILE) modular microfluidic platform for mimicking multi-organ interactions.

Ong LJY, Ching T, Chong LH, Arora S, Li H, Hashimoto M, DasGupta R, Yuen PK, Toh YC.

Lab Chip. 2019 Jun 25;19(13):2178-2191. doi: 10.1039/c9lc00160c.


Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling.

Zak M, Hanan EJ, Lupardus P, Brown DG, Robinson C, Siu M, Lyssikatos JP, Romero FA, Zhao G, Kellar T, Mendonca R, Ray NC, Goodacre SC, Crackett PH, McLean N, Hurley CA, Yuen PW, Cheng YX, Liu X, Liimatta M, Kohli PB, Nonomiya J, Salmon G, Buckley G, Lloyd J, Gibbons P, Ghilardi N, Kenny JR, Johnson A.

Bioorg Med Chem Lett. 2019 Jun 15;29(12):1522-1531. doi: 10.1016/j.bmcl.2019.04.008. Epub 2019 Apr 4.


Gut Leakage of Fungal-Derived Inflammatory Mediators: Part of a Gut-Liver-Kidney Axis in Bacterial Sepsis.

Amornphimoltham P, Yuen PST, Star RA, Leelahavanichkul A.

Dig Dis Sci. 2019 Sep;64(9):2416-2428. doi: 10.1007/s10620-019-05581-y. Epub 2019 Mar 13. Review.


A Hybrid Residual Network and Long Short-Term Memory Method for Peptic Ulcer Bleeding Mortality Prediction.

Tan Q, Ma AJ, Deng H, Wong VW, Tse YK, Yip TC, Wong GL, Ching JY, Chan FK, Yuen PC.

AMIA Annu Symp Proc. 2018 Dec 5;2018:998-1007. eCollection 2018.


Machine learning model to predict recurrent ulcer bleeding in patients with history of idiopathic gastroduodenal ulcer bleeding.

Wong GL, Ma AJ, Deng H, Ching JY, Wong VW, Tse YK, Yip TC, Lau LH, Liu HH, Leung CM, Tsang SW, Chan CW, Lau JY, Yuen PC, Chan FK.

Aliment Pharmacol Ther. 2019 Apr;49(7):912-918. doi: 10.1111/apt.15145. Epub 2019 Feb 13.


Dynamic Graph Co-Matching for Unsupervised Video-based Person Re-Identification.

Ye M, Li J, Ma AJ, Zheng L, Yuen PC.

IEEE Trans Image Process. 2019 Jan 14. doi: 10.1109/TIP.2019.2893066. [Epub ahead of print]


Dysphagia due to massive retropharyngeal and pre-vertebral abscess.

Hendriks T, Quick M, Yuen P.

BMJ Case Rep. 2018 Nov 28;11(1). pii: e228162. doi: 10.1136/bcr-2018-228162. No abstract available.


Targeting Base Excision Repair Glycosylases with DNA Containing Transition State Mimics Prepared via Click Chemistry.

Yuen PK, Green SA, Ashby J, Lay KT, Santra A, Chen X, Horvath MP, David SS.

ACS Chem Biol. 2019 Jan 18;14(1):27-36. doi: 10.1021/acschembio.8b00771. Epub 2019 Jan 2.


On the Reconstruction of Face Images from Deep Face Templates.

Mai G, Cao K, Yuen PC, Jain AK.

IEEE Trans Pattern Anal Mach Intell. 2019 May;41(5):1188-1202. doi: 10.1109/TPAMI.2018.2827389. Epub 2018 Apr 16.


Learning Common and Feature-Specific Patterns: A Novel Multiple-Sparse-Representation-Based Tracker.

Xiangyuan Lan, Shengping Zhang, Yuen PC, Chellappa R.

IEEE Trans Image Process. 2018 Apr;27(4):2022-2037. doi: 10.1109/TIP.2017.2777183. Epub 2017 Nov 23.


A Silica-Aerogel-Reinforced Composite Polymer Electrolyte with High Ionic Conductivity and High Modulus.

Lin D, Yuen PY, Liu Y, Liu W, Liu N, Dauskardt RH, Cui Y.

Adv Mater. 2018 Aug;30(32):e1802661. doi: 10.1002/adma.201802661. Epub 2018 Jun 25.


Aminoisoxazoles as Potent Inhibitors of Tryptophan 2,3-Dioxygenase 2 (TDO2).

Pei Z, Mendonca R, Gazzard L, Pastor R, Goon L, Gustafson A, VanderPorten E, Hatzivassiliou G, Dement K, Cass R, Yuen PW, Zhang Y, Wu G, Lin X, Liu Y, Sellers BD.

ACS Med Chem Lett. 2018 Apr 2;9(5):417-421. doi: 10.1021/acsmedchemlett.7b00427. eCollection 2018 May 10.


Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling.

Chen H, Volgraf M, Do S, Kolesnikov A, Shore DG, Verma VA, Villemure E, Wang L, Chen Y, Hu B, Lu AJ, Wu G, Xu X, Yuen PW, Zhang Y, Erickson SD, Dahl M, Brotherton-Pleiss C, Tay S, Ly JQ, Murray LJ, Chen J, Amm D, Lange W, Hackos DH, Reese RM, Shields SD, Lyssikatos JP, Safina BS, Estrada AA.

J Med Chem. 2018 Apr 26;61(8):3641-3659. doi: 10.1021/acs.jmedchem.8b00117. Epub 2018 Apr 12.


Two approaches for estimating the lower limit of quantitation (LLOQ) of microRNA levels assayed as exploratory biomarkers by RT-qPCR.

Wolfinger RD, Beedanagari S, Boitier E, Chen T, Couttet P, Ellinger-Ziegelbauer H, Guillemain G, Mariet C, Mouritzen P, O'Lone R, Pine PS, Sharapova T, Yan J, Yuen PS, Thompson KL.

BMC Biotechnol. 2018 Feb 2;18(1):6. doi: 10.1186/s12896-018-0415-4.


Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas.

Bircsak KM, Moscovitz JE, Wen X, Archer F, Yuen PYS, Mohammed M, Memon N, Weinberger BI, Saba LM, Vetrano AM, Aleksunes LM.

Drug Metab Dispos. 2018 May;46(5):619-627. doi: 10.1124/dmd.117.079228. Epub 2018 Jan 31.


The role of adenosine 1a receptor signaling on GFR early after the induction of sepsis.

Street JM, Koritzinsky EH, Bellomo TR, Hu X, Yuen PST, Star RA.

Am J Physiol Renal Physiol. 2018 May 1;314(5):F788-F797. doi: 10.1152/ajprenal.00051.2017. Epub 2017 Nov 8.


Selective base excision repair of DNA damage by the non-base-flipping DNA glycosylase AlkC.

Shi R, Mullins EA, Shen XX, Lay KT, Yuen PK, David SS, Rokas A, Eichman BF.

EMBO J. 2018 Jan 4;37(1):63-74. doi: 10.15252/embj.201797833. Epub 2017 Oct 20.


Editorial: progress towards a simple tool for screening for hepatic steatosis in the general population - authors' reply.

Yip TC, Ma AJ, Yuen PC, Wong GL.

Aliment Pharmacol Ther. 2017 Sep;46(5):560-561. doi: 10.1111/apt.14234. No abstract available.


Urine Exosome Isolation and Characterization.

Street JM, Koritzinsky EH, Glispie DM, Yuen PST.

Methods Mol Biol. 2017;1641:413-423. doi: 10.1007/978-1-4939-7172-5_23.


Mitochondrial DNA-enriched microparticles promote acute-on-chronic alcoholic neutrophilia and hepatotoxicity.

Cai Y, Xu MJ, Koritzinsky EH, Zhou Z, Wang W, Cao H, Yuen PS, Ross RA, Star RA, Liangpunsakul S, Gao B.

JCI Insight. 2017 Jul 20;2(14). pii: 92634. doi: 10.1172/jci.insight.92634. eCollection 2017 Jul 20.


Inference-Based Similarity Search in Randomized Montgomery Domains for Privacy-Preserving Biometric Identification.

Wang Y, Wan J, Guo J, Cheung YM, Yuen PC, Yi Wang, Jianwu Wan, Jun Guo, Yiu-Ming Cheung, Yuen PC, Cheung YM, Guo J, Yuen PC, Wan J, Wang Y.

IEEE Trans Pattern Anal Mach Intell. 2018 Jul;40(7):1611-1624. doi: 10.1109/TPAMI.2017.2727048. Epub 2017 Jul 14.


Laboratory parameter-based machine learning model for excluding non-alcoholic fatty liver disease (NAFLD) in the general population.

Yip TC, Ma AJ, Wong VW, Tse YK, Chan HL, Yuen PC, Wong GL.

Aliment Pharmacol Ther. 2017 Aug;46(4):447-456. doi: 10.1111/apt.14172. Epub 2017 Jun 6.


Human SR-BII mediates SAA uptake and contributes to SAA pro-inflammatory signaling in vitro and in vivo.

Baranova IN, Souza ACP, Bocharov AV, Vishnyakova TG, Hu X, Vaisman BL, Amar MJ, Chen Z, Remaley AT, Patterson AP, Yuen PST, Star RA, Eggerman TL.

PLoS One. 2017 Apr 19;12(4):e0175824. doi: 10.1371/journal.pone.0175824. eCollection 2017.


CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus.

Faridi MH, Khan SQ, Zhao W, Lee HW, Altintas MM, Zhang K, Kumar V, Armstrong AR, Carmona-Rivera C, Dorschner JM, Schnaith AM, Li X, Ghodke-Puranik Y, Moore E, Purmalek M, Irizarry-Caro J, Zhang T, Day R, Stoub D, Hoffmann V, Khaliqdina SJ, Bhargava P, Santander AM, Torroella-Kouri M, Issac B, Cimbaluk DJ, Zloza A, Prabhakar R, Deep S, Jolly M, Koh KH, Reichner JS, Bradshaw EM, Chen J, Moita LF, Yuen PS, Li Tsai W, Singh B, Reiser J, Nath SK, Niewold TB, Vazquez-Padron RI, Kaplan MJ, Gupta V.

J Clin Invest. 2017 Apr 3;127(4):1271-1283. doi: 10.1172/JCI88442. Epub 2017 Mar 6.


A cross-sectional study on compliance with topical glaucoma medication and its associated socioeconomic burden for a Chinese population.

Lui MH, Lam JC, Kwong YL, Wong TS, Cheung PL, Lai SS, Yuen PL, Lam WY, Chan HY, Wong YF, Lai JS, Shih KC.

Int J Ophthalmol. 2017 Feb 18;10(2):293-299. doi: 10.18240/ijo.2017.02.18. eCollection 2017.


GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile.

Villemure E, Volgraf M, Jiang Y, Wu G, Ly CQ, Yuen PW, Lu A, Luo X, Liu M, Zhang S, Lupardus PJ, Wallweber HJ, Liederer BM, Deshmukh G, Plise E, Tay S, Wang TM, Hanson JE, Hackos DH, Scearce-Levie K, Schwarz JB, Sellers BD.

ACS Med Chem Lett. 2016 Oct 31;8(1):84-89. doi: 10.1021/acsmedchemlett.6b00388. eCollection 2017 Jan 12.


Urine Exosomes: An Emerging Trove of Biomarkers.

Street JM, Koritzinsky EH, Glispie DM, Star RA, Yuen PS.

Adv Clin Chem. 2017;78:103-122. doi: 10.1016/bs.acc.2016.07.003. Epub 2016 Aug 18. Review.


An Artificial Solid Electrolyte Interphase with High Li-Ion Conductivity, Mechanical Strength, and Flexibility for Stable Lithium Metal Anodes.

Liu Y, Lin D, Yuen PY, Liu K, Xie J, Dauskardt RH, Cui Y.

Adv Mater. 2017 Mar;29(10). doi: 10.1002/adma.201605531. Epub 2016 Dec 29.


A Novel Microfluidic Assay for Rapid Phenotypic Antibiotic Susceptibility Testing of Bacteria Detected in Clinical Blood Cultures.

Malmberg C, Yuen P, Spaak J, Cars O, Tängdén T, Lagerbäck P.

PLoS One. 2016 Dec 14;11(12):e0167356. doi: 10.1371/journal.pone.0167356. eCollection 2016.


Absolute Measurement of Cardiac Injury-Induced microRNAs in Biofluids across Multiple Test Sites.

Thompson KL, Boitier E, Chen T, Couttet P, Ellinger-Ziegelbauer H, Goetschy M, Guillemain G, Kanki M, Kelsall J, Mariet C, de La Moureyre-Spire C, Mouritzen P, Nassirpour R, O'Lone R, Pine PS, Rosenzweig BA, Sharapova T, Smith A, Uchiyama H, Yan J, Yuen PS, Wolfinger R.

Toxicol Sci. 2016 Nov;154(1):115-125. Epub 2016 Sep 7.


Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors.

Zak M, Yuen PW, Liu X, Patel S, Sampath D, Oeh J, Liederer BM, Wang W, O'Brien T, Xiao Y, Skelton N, Hua R, Sodhi J, Wang Y, Zhang L, Zhao G, Zheng X, Ho YC, Bair KW, Dragovich PS.

J Med Chem. 2016 Sep 22;59(18):8345-68. doi: 10.1021/acs.jmedchem.6b00697. Epub 2016 Aug 30.


Embedding objects during 3D printing to add new functionalities.

Yuen PK.

Biomicrofluidics. 2016 Jul 13;10(4):044104. doi: 10.1063/1.4958909. eCollection 2016 Jul.


Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock.

Voss OH, Murakami Y, Pena MY, Lee HN, Tian L, Margulies DH, Street JM, Yuen PS, Qi CF, Krzewski K, Coligan JE.

Immunity. 2016 Jun 21;44(6):1365-78. doi: 10.1016/j.immuni.2016.05.005. Epub 2016 May 31.


Quantification of Exosomes.

Koritzinsky EH, Street JM, Star RA, Yuen PS.

J Cell Physiol. 2017 Jul;232(7):1587-1590. doi: 10.1002/jcp.25387. Epub 2017 Mar 1. Review.


Antagonism of scavenger receptor CD36 by 5A peptide prevents chronic kidney disease progression in mice independent of blood pressure regulation.

Souza AC, Bocharov AV, Baranova IN, Vishnyakova TG, Huang YG, Wilkins KJ, Hu X, Street JM, Alvarez-Prats A, Mullick AE, Patterson AP, Remaley AT, Eggerman TL, Yuen PS, Star RA.

Kidney Int. 2016 Apr;89(4):809-22. doi: 10.1016/j.kint.2015.12.043.


Human SR-BI and SR-BII Potentiate Lipopolysaccharide-Induced Inflammation and Acute Liver and Kidney Injury in Mice.

Baranova IN, Souza AC, Bocharov AV, Vishnyakova TG, Hu X, Vaisman BL, Amar MJ, Chen Z, Kost Y, Remaley AT, Patterson AP, Yuen PS, Star RA, Eggerman TL.

J Immunol. 2016 Apr 1;196(7):3135-47. doi: 10.4049/jimmunol.1501709. Epub 2016 Mar 2.


Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.

Volgraf M, Sellers BD, Jiang Y, Wu G, Ly CQ, Villemure E, Pastor RM, Yuen PW, Lu A, Luo X, Liu M, Zhang S, Sun L, Fu Y, Lupardus PJ, Wallweber HJ, Liederer BM, Deshmukh G, Plise E, Tay S, Reynen P, Herrington J, Gustafson A, Liu Y, Dirksen A, Dietz MG, Liu Y, Wang TM, Hanson JE, Hackos D, Scearce-Levie K, Schwarz JB.

J Med Chem. 2016 Mar 24;59(6):2760-79. doi: 10.1021/acs.jmedchem.5b02010. Epub 2016 Mar 8.


Genetic and Dietary Regulation of Glyburide Efflux by the Human Placental Breast Cancer Resistance Protein Transporter.

Bircsak KM, Gupta V, Yuen PY, Gorczyca L, Weinberger BI, Vetrano AM, Aleksunes LM.

J Pharmacol Exp Ther. 2016 Apr;357(1):103-13. doi: 10.1124/jpet.115.230185. Epub 2016 Feb 5.


Medical Savings Account balance and outpatient utilization: Evidence from Guangzhou, China.

Zhang H, Yuen PP.

Soc Sci Med. 2016 Feb;151:1-10. doi: 10.1016/j.socscimed.2015.12.035. Epub 2015 Dec 25.


The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.

Mullins EA, Shi R, Parsons ZD, Yuen PK, David SS, Igarashi Y, Eichman BF.

Nature. 2015 Nov 12;527(7577):254-8. doi: 10.1038/nature15728. Epub 2015 Oct 28.


Indiscernible Benefit of Double-Unit Umbilical Cord Blood Transplantation in Children: A Single-Center Experience From Hong Kong.

Tsang KS, Leung AW, Lee V, Cheng FW, Shing MM, Pong HN, Leung TF, Yuen PM, Li CK.

Cell Transplant. 2016;25(7):1277-86. doi: 10.3727/096368915X689631. Epub 2015 Oct 1.


The Authors Reply.

Souza AC, Yuen PS, Star RA.

Kidney Int. 2015 Oct;88(4):915-6. doi: 10.1038/ki.2015.209. No abstract available.


TLR4 mutant mice are protected from renal fibrosis and chronic kidney disease progression.

Souza AC, Tsuji T, Baranova IN, Bocharov AV, Wilkins KJ, Street JM, Alvarez-Prats A, Hu X, Eggerman T, Yuen PS, Star RA.

Physiol Rep. 2015 Sep;3(9). pii: e12558. doi: 10.14814/phy2.12558.


Joint Sparse Representation and Robust Feature-Level Fusion for Multi-Cue Visual Tracking.

Lan X, Ma AJ, Yuen PC, Chellappa R.

IEEE Trans Image Process. 2015 Dec;24(12):5826-41. doi: 10.1109/TIP.2015.2481325. Epub 2015 Sep 23.


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