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Does Chronic Kidney Disease-Induced Cognitive Impairment Affect Driving Safety?

Kepecs DM, Glick L, Silver SA, Yuen DA.

Can J Kidney Health Dis. 2018 Jun 17;5:2054358118777133. doi: 10.1177/2054358118777133. eCollection 2018.


Sources and transformation pathways for dichlorodiphenyltrichloroethane (DDT) and metabolites in soils from Northwest Fujian, China.

Huang H, Zhang Y, Chen W, Chen W, Yuen DA, Ding Y, Chen Y, Mao Y, Qi S.

Environ Pollut. 2018 Apr;235:560-570. doi: 10.1016/j.envpol.2017.12.071. Epub 2018 Jan 9.


Magnetic Resonance Elastography to Assess Fibrosis in Kidney Allografts.

Kirpalani A, Hashim E, Leung G, Kim JK, Krizova A, Jothy S, Deeb M, Jiang NN, Glick L, Mnatzakanian G, Yuen DA.

Clin J Am Soc Nephrol. 2017 Oct 6;12(10):1671-1679. doi: 10.2215/CJN.01830217. Epub 2017 Aug 30.


Role of Magnetic Resonance Elastography as a Noninvasive Measurement Tool of Fibrosis in a Renal Allograft: A Case Report.

Kim JK, Yuen DA, Leung G, Jothy S, Zaltzman J, Ramesh Prasad GV, Prabhudesai V, Mnatzakanian G, Kirpalani A.

Transplant Proc. 2017 Sep;49(7):1555-1559. doi: 10.1016/j.transproceed.2017.04.002.


The role of thrombectomy and diffusion-weighted imaging with MRI in post-transplant renal vein thrombosis: a case report.

Misra P, Kirpalani A, Leung G, Vlachou PA, Lee JY, Jothy S, Zaltzman J, Yuen DA.

BMC Nephrol. 2017 Jul 10;18(1):224. doi: 10.1186/s12882-017-0618-2.


Relationship between changes in blood pressure and left ventricular mass over 1 year in end-stage renal disease.

Sarak B, Wald R, Goldstein MB, Deva DP, Leipsic J, Kiaii M, Leung G, Barfett JJ, Perl J, Yuen DA, Connelly KA, Yan AT.

J Hypertens. 2017 Aug;35(8):1709-1716. doi: 10.1097/HJH.0000000000001353.


Could MRI Be Used To Image Kidney Fibrosis? A Review of Recent Advances and Remaining Barriers.

Leung G, Kirpalani A, Szeto SG, Deeb M, Foltz W, Simmons CA, Yuen DA.

Clin J Am Soc Nephrol. 2017 Jun 7;12(6):1019-1028. doi: 10.2215/CJN.07900716. Epub 2017 Mar 15. Review.


Relationships Between Left Ventricular Structure and Function According to Cardiac MRI and Cardiac Biomarkers in End-Stage Renal Disease.

Ross BA, Wald R, Goldstein MB, Yuen DA, Leipsic J, Kiaii M, Rathe A, Deva DP, Kirpalani A, Bello OO, Graham JJ, Leong-Poi H, Connelly KA, Yan AT.

Can J Cardiol. 2017 Apr;33(4):501-507. doi: 10.1016/j.cjca.2016.11.021. Epub 2016 Dec 3.


Progenitor cell secretory products exert additive renoprotective effects when combined with ace inhibitors in experimental CKD.

Kepecs DM, Yuen DA, Zhang Y, Thai K, Connelly KA, Gilbert RE.

J Renin Angiotensin Aldosterone Syst. 2016 Sep 15;17(3). pii: 1470320316668434. doi: 10.1177/1470320316668434. Print 2016 Jul.


YAP/TAZ Are Mechanoregulators of TGF-β-Smad Signaling and Renal Fibrogenesis.

Szeto SG, Narimatsu M, Lu M, He X, Sidiqi AM, Tolosa MF, Chan L, De Freitas K, Bialik JF, Majumder S, Boo S, Hinz B, Dan Q, Advani A, John R, Wrana JL, Kapus A, Yuen DA.

J Am Soc Nephrol. 2016 Oct;27(10):3117-3128. doi: 10.1681/ASN.2015050499. Epub 2016 Mar 9.


Recombinant N-Terminal Slit2 Inhibits TGF-β-Induced Fibroblast Activation and Renal Fibrosis.

Yuen DA, Huang YW, Liu GY, Patel S, Fang F, Zhou J, Thai K, Sidiqi A, Szeto SG, Chan L, Lu M, He X, John R, Gilbert RE, Scholey JW, Robinson LA.

J Am Soc Nephrol. 2016 Sep;27(9):2609-15. doi: 10.1681/ASN.2015040356. Epub 2016 Feb 11.


Repeated treatment with bone marrow cell secretory products maintains long-term renoprotection in experimental chronic kidney disease: a placebo-controlled trial.

Yuen DA, Kepecs DM, Zhang Y, Advani S, Thai K, Connelly KA, Gilbert RE.

Can J Kidney Health Dis. 2015 Nov 14;2:44. doi: 10.1186/s40697-015-0082-5. eCollection 2015.


Polycyclic aromatic hydrocarbons (PAHs) in multimedia environment of Heshan coal district, Guangxi: distribution, source diagnosis and health risk assessment.

Huang HF, Xing XL, Zhang ZZ, Qi SH, Yang D, Yuen DA, Sandy EH, Zhou AG, Li XQ.

Environ Geochem Health. 2016 Oct;38(5):1169-81. doi: 10.1007/s10653-015-9781-1. Epub 2015 Nov 12.


Myocardin-related Transcription Factor Regulates Nox4 Protein Expression: LINKING CYTOSKELETAL ORGANIZATION TO REDOX STATE.

Rozycki M, Bialik JF, Speight P, Dan Q, Knudsen TE, Szeto SG, Yuen DA, Szászi K, Pedersen SF, Kapus A.

J Biol Chem. 2016 Jan 1;291(1):227-43. doi: 10.1074/jbc.M115.674606. Epub 2015 Nov 10.


Early outgrowth pro-angiogenic cell number and function do not correlate with left ventricular structure and function in conventional hemodialysis patients: a cross-sectional study.

Lineen JR, Kuliszewski M, Dacouris N, Liao C, Rudenko D, Deva DP, Goldstein M, Leong-Poi H, Wald R, Yan AT, Yuen DA.

Can J Kidney Health Dis. 2015 Jul 30;2:25. doi: 10.1186/s40697-015-0060-y. eCollection 2015.


Application of Modular Therapy for Renoprotection in Experimental Chronic Kidney Disease.

Kepecs DM, Zhang Y, Thai K, Advani SL, Yuen DA, Connelly KA, Kosanam H, Diamandis E, Sefton MV, Gilbert RE.

Tissue Eng Part A. 2015 Jul;21(13-14):1963-72. doi: 10.1089/ten.TEA.2014.0017. Epub 2015 Mar 20.


A clinical and pathological variant of acute transplant glomerulopathy.

Molnar MZ, Prasad GV, Yuen DA, Jothy S, Zaltzman JS.

Case Rep Pathol. 2014;2014:961987. doi: 10.1155/2014/961987. Epub 2014 Sep 11.


SDF-1/CXCR4 signaling preserves microvascular integrity and renal function in chronic kidney disease.

Chen LH, Advani SL, Thai K, Kabir MG, Sood MM, Gibson IW, Yuen DA, Connelly KA, Marsden PA, Kelly DJ, Gilbert RE, Advani A.

PLoS One. 2014 Mar 17;9(3):e92227. doi: 10.1371/journal.pone.0092227. eCollection 2014.


Bridging the gap: a Canadian perspective on translational kidney research.

Molnar AO, Yuen DA, Tangri N, Jensen VL.

Can J Kidney Health Dis. 2014 Aug 29;1:18. doi: 10.1186/s40697-014-0018-5. eCollection 2014.


Correlates of left ventricular mass in chronic hemodialysis recipients.

Wald R, Goldstein MB, Wald RM, Harel Z, Kirpalani A, Perl J, Yuen DA, Wolf MS, Yan AT.

Int J Cardiovasc Imaging. 2014 Feb;30(2):349-56. doi: 10.1007/s10554-013-0337-0. Epub 2013 Nov 30.


Early outgrowth cells release soluble endocrine antifibrotic factors that reduce progressive organ fibrosis.

Yuen DA, Connelly KA, Zhang Y, Advani SL, Thai K, Kabir G, Kepecs D, Spring C, Smith C, Batruch I, Kosanam H, Advani A, Diamandis E, Marsden PA, Gilbert RE.

Stem Cells. 2013 Nov;31(11):2408-19. doi: 10.1002/stem.1502.


Slit2 prevents neutrophil recruitment and renal ischemia-reperfusion injury.

Chaturvedi S, Yuen DA, Bajwa A, Huang YW, Sokollik C, Huang L, Lam GY, Tole S, Liu GY, Pan J, Chan L, Sokolskyy Y, Puthia M, Godaly G, John R, Wang C, Lee WL, Brumell JH, Okusa MD, Robinson LA.

J Am Soc Nephrol. 2013 Jul;24(8):1274-87. doi: 10.1681/ASN.2012090890. Epub 2013 Jun 13.


Slit2-Robo signaling: a novel regulator of vascular injury.

Yuen DA, Robinson LA.

Curr Opin Nephrol Hypertens. 2013 Jul;22(4):445-51. doi: 10.1097/MNH.0b013e32836235f4. Review.


Angiogenic dysfunction in bone marrow-derived early outgrowth cells from diabetic animals is attenuated by SIRT1 activation.

Yuen DA, Zhang Y, Thai K, Spring C, Chan L, Guo X, Advani A, Sivak JM, Gilbert RE.

Stem Cells Transl Med. 2012 Dec;1(12):921-6. doi: 10.5966/sctm.2012-0026. Epub 2012 Nov 26.


Comparative assessment of 2-dimensional echocardiography vs cardiac magnetic resonance imaging in measuring left ventricular mass in patients with and without end-stage renal disease.

Jakubovic BD, Wald R, Goldstein MB, Leong-Poi H, Yuen DA, Perl J, Lima JA, Liu JJ, Kirpalani A, Dacouris N, Wald R, Connelly KA, Yan AT.

Can J Cardiol. 2013 Mar;29(3):384-90. doi: 10.1016/j.cjca.2012.07.013. Epub 2012 Oct 25.


Cell therapy for diabetic nephropathy: is the future, now?

Gilbert RE, Zhang Y, Yuen DA.

Semin Nephrol. 2012 Sep;32(5):486-93. doi: 10.1016/j.semnephrol.2012.07.012.


eNOS deficiency predisposes podocytes to injury in diabetes.

Yuen DA, Stead BE, Zhang Y, White KE, Kabir MG, Thai K, Advani SL, Connelly KA, Takano T, Zhu L, Cox AJ, Kelly DJ, Gibson IW, Takahashi T, Harris RC, Advani A.

J Am Soc Nephrol. 2012 Nov;23(11):1810-23. doi: 10.1681/ASN.2011121170. Epub 2012 Sep 20.


DPP-4 inhibition attenuates cardiac dysfunction and adverse remodeling following myocardial infarction in rats with experimental diabetes.

Connelly KA, Zhang Y, Advani A, Advani SL, Thai K, Yuen DA, Gilbert RE.

Cardiovasc Ther. 2013 Oct;31(5):259-67. doi: 10.1111/1755-5922.12005.


Hyperglycemia and renal mass ablation synergistically augment albuminuria in the diabetic subtotally nephrectomized rat: implications for modeling diabetic nephropathy.

Chen LH, Stead B, Advani SL, Yaqoob N, Thai K, Kabir MG, Yuen DA, Connelly KA, Gilbert RE, Advani A.

Nephron Extra. 2012 Jan;2(1):115-24. doi: 10.1159/000338272. Epub 2012 May 12.


Bone marrow cell therapies for endothelial repair and their relevance to kidney disease.

Yuen DA, Gilbert RE, Marsden PA.

Semin Nephrol. 2012 Mar;32(2):215-23. doi: 10.1016/j.semnephrol.2012.02.008. Review.


Early-outgrowth bone marrow cells attenuate renal injury and dysfunction via an antioxidant effect in a mouse model of type 2 diabetes.

Zhang Y, Yuen DA, Advani A, Thai K, Advani SL, Kepecs D, Kabir MG, Connelly KA, Gilbert RE.

Diabetes. 2012 Aug;61(8):2114-25. doi: 10.2337/db11-1365. Epub 2012 May 17.


The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice.

Petruzziello-Pellegrini TN, Yuen DA, Page AV, Patel S, Soltyk AM, Matouk CC, Wong DK, Turgeon PJ, Fish JE, Ho JJ, Steer BM, Khajoee V, Tigdi J, Lee WL, Motto DG, Advani A, Gilbert RE, Karumanchi SA, Robinson LA, Tarr PI, Liles WC, Brunton JL, Marsden PA.

J Clin Invest. 2012 Feb;122(2):759-76. doi: 10.1172/JCI57313. Epub 2012 Jan 9.


Fluorescent microangiography is a novel and widely applicable technique for delineating the renal microvasculature.

Advani A, Connelly KA, Yuen DA, Zhang Y, Advani SL, Trogadis J, Kabir MG, Shachar E, Kuliszewski MA, Leong-Poi H, Stewart DJ, Gilbert RE.

PLoS One. 2011;6(10):e24695. doi: 10.1371/journal.pone.0024695. Epub 2011 Oct 3.


Nocturnal hemodialysis is associated with restoration of early-outgrowth endothelial progenitor-like cell function.

Yuen DA, Kuliszewski MA, Liao C, Rudenko D, Leong-Poi H, Chan CT.

Clin J Am Soc Nephrol. 2011 Jun;6(6):1345-53. doi: 10.2215/CJN.10911210. Epub 2011 May 19.


Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism.

Advani A, Huang Q, Thai K, Advani SL, White KE, Kelly DJ, Yuen DA, Connelly KA, Marsden PA, Gilbert RE.

Am J Pathol. 2011 May;178(5):2205-14. doi: 10.1016/j.ajpath.2011.01.044.


Histone deacetylase inhibition attenuates diabetes-associated kidney growth: potential role for epigenetic modification of the epidermal growth factor receptor.

Gilbert RE, Huang Q, Thai K, Advani SL, Lee K, Yuen DA, Connelly KA, Advani A.

Kidney Int. 2011 Jun;79(12):1312-21. doi: 10.1038/ki.2011.39. Epub 2011 Mar 9.


Culture-modified bone marrow cells attenuate cardiac and renal injury in a chronic kidney disease rat model via a novel antifibrotic mechanism.

Yuen DA, Connelly KA, Advani A, Liao C, Kuliszewski MA, Trogadis J, Thai K, Advani SL, Zhang Y, Kelly DJ, Leong-Poi H, Keating A, Marsden PA, Stewart DJ, Gilbert RE.

PLoS One. 2010 Mar 4;5(3):e9543. doi: 10.1371/journal.pone.0009543.


A 3-D model of tumor progression based on complex automata driven by particle dynamics.

Wcisło R, Dzwinel W, Yuen DA, Dudek AZ.

J Mol Model. 2009 Dec;15(12):1517-39. doi: 10.1007/s00894-009-0511-4. Epub 2009 May 23.


Anomalous compressibility of ferropericlase throughout the iron spin cross-over.

Wentzcovitch RM, Justo JF, Wu Z, da Silva CR, Yuen DA, Kohlstedt D.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8447-52. doi: 10.1073/pnas.0812150106. Epub 2009 May 13.


Topology of the postperovskite phase transition and mantle dynamics.

Monnereau M, Yuen DA.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9156-61. Epub 2007 May 3.


Ensemble of linear models for predicting drug properties.

Arodź T, Yuen DA, Dudek AZ.

J Chem Inf Model. 2006 Jan-Feb;46(1):416-23.


Detection of clustered microcalcifications in small field digital mammography.

Arodź T, Kurdziel M, Popiela TJ, Sevre EO, Yuen DA.

Comput Methods Programs Biomed. 2006 Jan;81(1):56-65. Epub 2005 Nov 28.


Mesoscopic dispersion of colloidal agglomerate in a complex fluid modelled by a hybrid fluid-particle model.

Dzwinel W, Yuen DA.

J Colloid Interface Sci. 2002 Mar 15;247(2):463-80.


Pattern recognition techniques for automatic detection of suspicious-looking anomalies in mammograms.

Arodź T, Kurdziel M, Sevre EO, Yuen DA.

Comput Methods Programs Biomed. 2005 Aug;79(2):135-49.


Modeling fibrin aggregation in blood flow with discrete-particles.

Boryczko K, Dzwinel W, Yuen DA.

Comput Methods Programs Biomed. 2004 Sep;75(3):181-94.


Dynamical clustering of red blood cells in capillary vessels.

Boryczko K, Dzwinel W, Yuen DA.

J Mol Model. 2003 Feb;9(1):16-33. Epub 2003 Jan 16.


A discrete-particle model of blood dynamics in capillary vessels.

Dzwinel W, Boryczko K, Yuen DA.

J Colloid Interface Sci. 2003 Feb 1;258(1):163-73.


Mesoscopic dynamics of colloids simulated with dissipative particle dynamics and fluid particle model.

Dzwinel W, Yuen DA, Boryczko K.

J Mol Model. 2002 Jan;8(1):33-43.


Plumes and waves in two-dimensional turbulent thermal convection.

Vincent AP, Yuen DA.

Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1999 Sep;60(3):2957-63.


The initiation of subduction: criticality by addition of water?

Regenauer-Lieb K, Yuen DA, Branlund J.

Science. 2001 Oct 19;294(5542):578-80.

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