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Items: 10

1.

Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective.

Kenna JG, Taskar KS, Battista C, Bourdet DL, Brouwer KLR, Brouwer KR, Dai D, Funk C, Hafey MJ, Lai Y, Maher J, Pak YA, Pedersen JM, Polli JW, Rodrigues AD, Watkins PB, Yang K, Yucha RW; International Transporter Consortium.

Clin Pharmacol Ther. 2018 Nov;104(5):916-932. doi: 10.1002/cpt.1222. Review.

2.

Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics.

Bajaj P, Chowdhury SK, Yucha R, Kelly EJ, Xiao G.

Drug Metab Dispos. 2018 Nov;46(11):1692-1702. doi: 10.1124/dmd.118.082958. Epub 2018 Aug 3. Review.

PMID:
30076203
3.

Aggrecan-like biomimetic proteoglycans (BPGs) composed of natural chondroitin sulfate bristles grafted onto a poly(acrylic acid) core for molecular engineering of the extracellular matrix.

Prudnikova K, Lightfoot Vidal SE, Sarkar S, Yu T, Yucha RW, Ganesh N, Penn LS, Han L, Schauer CL, Vresilovic EJ, Marcolongo MS.

Acta Biomater. 2018 Jul 15;75:93-104. doi: 10.1016/j.actbio.2018.05.013. Epub 2018 Jun 1.

PMID:
29753911
4.

CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo.

Sebastian NT, Zaikos TD, Terry V, Taschuk F, McNamara LA, Onafuwa-Nuga A, Yucha R, Signer RAJ, Riddell J IV, Bixby D, Markowitz N, Morrison SJ, Collins KL.

PLoS Pathog. 2017 Jul 21;13(7):e1006509. doi: 10.1371/journal.ppat.1006509. eCollection 2017 Jul. Erratum in: PLoS Pathog. 2017 Sep 13;13(9):e1006617.

5.

High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay.

Yucha RW, Hobbs KS, Hanhauser E, Hogan LE, Nieves W, Ozen MO, Inci F, York V, Gibson EA, Thanh C, Shafiee H, El Assal R, Kiselinova M, Robles YP, Bae H, Leadabrand KS, Wang S, Deeks SG, Kuritzkes DR, Demirci U, Henrich TJ.

EBioMedicine. 2017 Jun;20:217-229. doi: 10.1016/j.ebiom.2017.05.006. Epub 2017 May 4.

6.

Biomimetic Proteoglycans Mimic Macromolecular Architecture and Water Uptake of Natural Proteoglycans.

Prudnikova K, Yucha RW, Patel P, Kriete AS, Han L, Penn LS, Marcolongo MS.

Biomacromolecules. 2017 Jun 12;18(6):1713-1723. doi: 10.1021/acs.biomac.7b00032. Epub 2017 May 1.

PMID:
28398752
7.

In Vitro Drug-Induced Liver Injury Prediction: Criteria Optimization of Efflux Transporter IC50 and Physicochemical Properties.

Yucha RW, He K, Shi Q, Cai L, Nakashita Y, Xia CQ, Liao M.

Toxicol Sci. 2017 Jun 1;157(2):487-499. doi: 10.1093/toxsci/kfx060.

PMID:
28369588
8.

Hierarchically ordered polymer nanofiber shish kebabs as a bone scaffold material.

Chen X, Gleeson SE, Yu T, Khan N, Yucha RW, Marcolongo M, Li CY.

J Biomed Mater Res A. 2017 Jun;105(6):1786-1798. doi: 10.1002/jbm.a.36039. Epub 2017 Apr 12.

PMID:
28198135
9.

Newly isolated mAbs broaden the neutralizing epitope in murine norovirus.

Kolawole AO, Xia C, Li M, Gamez M, Yu C, Rippinger CM, Yucha RE, Smith TJ, Wobus CE.

J Gen Virol. 2014 Sep;95(Pt 9):1958-68. doi: 10.1099/vir.0.066753-0. Epub 2014 Jun 4.

10.

Quantifying the biomechanics of conception: L-selectin-mediated blastocyst implantation mechanics with engineered "trophospheres".

Yucha RW, Jost M, Rothstein D, Robertson N, Marcolongo MS.

Tissue Eng Part A. 2014 Jan;20(1-2):189-96. doi: 10.1089/ten.TEA.2013.0067. Epub 2013 Oct 12.

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