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Items: 25

1.

FDA Approval: Uridine Triacetate for the Treatment of Patients Following Fluorouracil or Capecitabine Overdose or Exhibiting Early-Onset Severe Toxicities Following Administration of These Drugs.

Ison G, Beaver JA, McGuinn WD Jr, Palmby TR, Dinin J, Charlab R, Marathe A, Jin R, Liu Q, Chen XH, Ysern X, Stephens O, Bai G, Wang Y, Dorff SE, Cheng J, Tang S, Sridhara R, Pierce W, McKee AE, Ibrahim A, Kim G, Pazdur R.

Clin Cancer Res. 2016 Sep 15;22(18):4545-9. doi: 10.1158/1078-0432.CCR-16-0638. Epub 2016 Jul 11. Review.

2.

Three-dimensional structure of the complex between a T cell receptor beta chain and the superantigen staphylococcal enterotoxin B.

Li H, Llera A, Tsuchiya D, Leder L, Ysern X, Schlievert PM, Karjalainen K, Mariuzza RA.

Immunity. 1998 Dec;9(6):807-16.

3.

Imperfect interfaces.

Ysern X, Li H, Mariuzza RA.

Nat Struct Biol. 1998 Jun;5(6):412-4. No abstract available.

PMID:
9628472
4.

A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.

Dall'Acqua W, Goldman ER, Lin W, Teng C, Tsuchiya D, Li H, Ysern X, Braden BC, Li Y, Smith-Gill SJ, Mariuzza RA.

Biochemistry. 1998 Jun 2;37(22):7981-91.

PMID:
9609690
5.

Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.

Fields BA, Goldbaum FA, Dall'Acqua W, Malchiodi EL, Cauerhff A, Schwarz FP, Ysern X, Poljak RJ, Mariuzza RA.

Biochemistry. 1996 Dec 3;35(48):15494-503.

PMID:
8952503
6.

Crystal structure of an Fv-Fv idiotope-anti-idiotope complex at 1.9 A resolution.

Braden BC, Fields BA, Ysern X, Dall'Acqua W, Goldbaum FA, Poljak RJ, Mariuzza RA.

J Mol Biol. 1996 Nov 22;264(1):137-51.

PMID:
8950273
7.

Crystal structure of a T-cell receptor beta-chain complexed with a superantigen.

Fields BA, Malchiodi EL, Li H, Ysern X, Stauffacher CV, Schlievert PM, Karjalainen K, Mariuzza RA.

Nature. 1996 Nov 14;384(6605):188-92.

PMID:
8906797
8.

Crystal structure of the complex of the variable domain of antibody D1.3 and turkey egg white lysozyme: a novel conformational change in antibody CDR-L3 selects for antigen.

Braden BC, Fields BA, Ysern X, Goldbaum FA, Dall'Acqua W, Schwarz FP, Poljak RJ, Mariuzza RA.

J Mol Biol. 1996 Apr 19;257(5):889-94.

PMID:
8632472
9.

Crystal structure of the V alpha domain of a T cell antigen receptor.

Fields BA, Ober B, Malchiodi EL, Lebedeva MI, Braden BC, Ysern X, Kim JK, Shao X, Ward ES, Mariuzza RA.

Science. 1995 Dec 15;270(5243):1821-4.

PMID:
8525376
10.

Structure and thermodynamics of antigen recognition by antibodies.

Braden BC, Cauerhff A, Dall'Acqua W, Fields BA, Goldbaum FA, Malchiodi EL, Mariuzza RA, Poljak RJ, Schwarz FP, Ysern X, et al.

Ann N Y Acad Sci. 1995 Sep 29;764:315-27. No abstract available.

PMID:
7486542
11.

Molecular basis of antigen mimicry by an anti-idiotope.

Fields BA, Goldbaum FA, Ysern X, Poljak RJ, Mariuzza RA.

Nature. 1995 Apr 20;374(6524):739-42.

PMID:
7536303
12.

Protein motion and lock and key complementarity in antigen-antibody reactions.

Braden BC, Dall'Acqua W, Eisenstein E, Fields BA, Goldbaum FA, Malchiodi EL, Mariuzza RA, Schwarz FP, Ysern X, Poljak RJ.

Pharm Acta Helv. 1995 Mar;69(4):225-30. Review.

PMID:
7651966
13.

Crystallization and preliminary X-ray diffraction study of an idiotope-anti-idiotope Fv-Fv complex.

Goldbaum FA, Fields BA, Cauerhff A, Ysern X, Houdusse A, Eisele JL, Poljak RJ, Mariuzza RA.

J Mol Biol. 1994 Sep 2;241(5):739-43.

PMID:
8071997
14.

Crystallization and preliminary X-ray diffraction study of a bacterially produced T-cell antigen receptor V alpha domain.

Fields BA, Ysern X, Poljak RJ, Shao X, Ward ES, Mariuzza RA.

J Mol Biol. 1994 Jun 3;239(2):339-41.

PMID:
7515113
15.

Solvent rearrangement in an antigen-antibody interface introduced by site-directed mutagenesis of the antibody combining site.

Ysern X, Fields BA, Bhat TN, Goldbaum FA, Dall'Acqua W, Schwarz FP, Poljak RJ, Mariuzza RA.

J Mol Biol. 1994 May 13;238(4):496-500.

PMID:
8176740
16.

Three-dimensional structure and thermodynamics of antigen binding by anti-lysozyme antibodies.

Tello D, Goldbaum FA, Mariuzza RA, Ysern X, Schwarz FP, Poljak RJ.

Biochem Soc Trans. 1993 Nov;21(4):943-6. No abstract available.

PMID:
8132099
17.

Mitochondrial ATP synthase. Quaternary structure of the F1 moiety at 3.6 A determined by x-ray diffraction analysis.

Bianchet M, Ysern X, Hullihen J, Pedersen PL, Amzel LM.

J Biol Chem. 1991 Nov 5;266(31):21197-201.

18.

Cystic fibrosis transmembrane conductance regulator: nucleotide binding to a synthetic peptide.

Thomas PJ, Shenbagamurthi P, Ysern X, Pedersen PL.

Science. 1991 Feb 1;251(4993):555-7.

PMID:
1703660
19.
21.
22.

ATP synthases--structure of the F1-moiety and its relationship to function and mechanism.

Ysern X, Amzel LM, Pedersen PL.

J Bioenerg Biomembr. 1988 Aug;20(4):423-50. Review.

PMID:
2906060
23.

Preliminary X-ray diffraction analysis of HhaII endonuclease-DNA cocrystals.

Chandrasegaran S, Smith HO, Amzel ML, Ysern X.

Proteins. 1986 Nov;1(3):263-6.

PMID:
2835764
24.

Comparative studies of pig platelet membrane proteins.

Bubis J, Ysern X.

Comp Biochem Physiol B. 1983;75(2):245-53.

PMID:
6872515
25.

Three-dimensional structure and diversity of immunoglobulins.

Poljak RJ, Amzel LM, Chen BL, Chiu YY, Phizackerley RP, Saul F, Ysern X.

Cold Spring Harb Symp Quant Biol. 1977;41 Pt 2:639-45. No abstract available.

PMID:
268249

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