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Items: 1 to 50 of 92

1.

Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection.

Comar CE, Goldstein SA, Li Y, Yount B, Baric RS, Weiss SR.

MBio. 2019 Mar 26;10(2). pii: e00319-19. doi: 10.1128/mBio.00319-19.

2.

Beyond Neutralizing Antibody Levels: The Epitope Specificity of Antibodies Induced by National Institutes of Health Monovalent Dengue Virus Vaccines.

Swanstrom JA, Nivarthi UK, Patel B, Delacruz MJ, Yount B, Widman DG, Durbin AP, Whitehead SS, De Silva AM, Baric RS.

J Infect Dis. 2019 Jun 19;220(2):219-227. doi: 10.1093/infdis/jiz109.

3.

The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis.

Chefer S, Seidel J, Cockrell AS, Yount B, Solomon J, Hagen KR, Liu DX, Huzella LM, Kumar MR, Postnikova E, Bohannon JK, Lackemeyer MG, Cooper K, Endlich-Frazier A, Sharma H, Thomasson D, Bartos C, Sayre PJ, Sims A, Dyall J, Holbrook MR, Jahrling PB, Baric RS, Johnson RF.

mSphere. 2018 Dec 12;3(6). pii: e00540-18. doi: 10.1128/mSphere.00540-18.

4.

Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform.

Graham RL, Deming DJ, Deming ME, Yount BL, Baric RS.

Commun Biol. 2018 Oct 29;1:179. doi: 10.1038/s42003-018-0175-7. eCollection 2018.

5.

Genetic Variation between Dengue Virus Type 4 Strains Impacts Human Antibody Binding and Neutralization.

Gallichotte EN, Baric TJ, Nivarthi U, Delacruz MJ, Graham R, Widman DG, Yount BL, Durbin AP, Whitehead SS, de Silva AM, Baric RS.

Cell Rep. 2018 Oct 30;25(5):1214-1224. doi: 10.1016/j.celrep.2018.10.006.

6.

Human Norovirus Epitope D Plasticity Allows Escape from Antibody Immunity without Loss of Capacity for Binding Cellular Ligands.

Lindesmith LC, Brewer-Jensen PD, Mallory ML, Yount B, Collins MH, Debbink K, Graham RL, Baric RS.

J Virol. 2019 Jan 4;93(2). pii: e01813-18. doi: 10.1128/JVI.01813-18. Print 2019 Jan 15.

7.

Using survival analysis to predict septic shock onset in ICU patients.

Dummitt B, Zeringue A, Palagiri A, Veremakis C, Burch B, Yount B.

J Crit Care. 2018 Dec;48:339-344. doi: 10.1016/j.jcrc.2018.08.041. Epub 2018 Sep 12.

PMID:
30290359
8.

Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines.

Menachery VD, Gralinski LE, Mitchell HD, Dinnon KH 3rd, Leist SR, Yount BL Jr, McAnarney ET, Graham RL, Waters KM, Baric RS.

J Virol. 2018 Aug 16;92(17). pii: e00710-18. doi: 10.1128/JVI.00710-18. Print 2018 Sep 1.

9.

Analyzing the Human Serum Antibody Responses to a Live Attenuated Tetravalent Dengue Vaccine Candidate.

Swanstrom JA, Henein S, Plante JA, Yount BL, Widman DG, Gallichotte EN, Dean HJ, Osorio JE, Partidos CD, de Silva AM, Baric RS.

J Infect Dis. 2018 May 25;217(12):1932-1941. doi: 10.1093/infdis/jiy063.

10.

Bat Caliciviruses and Human Noroviruses Are Antigenically Similar and Have Overlapping Histo-Blood Group Antigen Binding Profiles.

Kocher JF, Lindesmith LC, Debbink K, Beall A, Mallory ML, Yount BL, Graham RL, Huynh J, Gates JE, Donaldson EF, Baric RS.

MBio. 2018 May 22;9(3). pii: e00869-18. doi: 10.1128/mBio.00869-18.

11.

An Immunocompetent Mouse Model of Zika Virus Infection.

Gorman MJ, Caine EA, Zaitsev K, Begley MC, Weger-Lucarelli J, Uccellini MB, Tripathi S, Morrison J, Yount BL, Dinnon KH 3rd, Rückert C, Young MC, Zhu Z, Robertson SJ, McNally KL, Ye J, Cao B, Mysorekar IU, Ebel GD, Baric RS, Best SM, Artyomov MN, Garcia-Sastre A, Diamond MS.

Cell Host Microbe. 2018 May 9;23(5):672-685.e6. doi: 10.1016/j.chom.2018.04.003.

12.

Human dengue virus serotype 2 neutralizing antibodies target two distinct quaternary epitopes.

Gallichotte EN, Baric TJ, Yount BL Jr, Widman DG, Durbin A, Whitehead S, Baric RS, de Silva AM.

PLoS Pathog. 2018 Feb 26;14(2):e1006934. doi: 10.1371/journal.ppat.1006934. eCollection 2018 Feb.

13.

Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3 into serotype 4.

Widman DG, Young E, Nivarthi U, Swanstrom JA, Royal SR, Yount BL, Debbink K, Begley M, Marcet S, Durbin A, de Silva AM, Messer WB, Baric RS.

Sci Rep. 2017 Dec 7;7(1):17169. doi: 10.1038/s41598-017-17355-5.

14.

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis.

Menachery VD, Gralinski LE, Mitchell HD, Dinnon KH 3rd, Leist SR, Yount BL Jr, Graham RL, McAnarney ET, Stratton KG, Cockrell AS, Debbink K, Sims AC, Waters KM, Baric RS.

mSphere. 2017 Nov 15;2(6). pii: e00346-17. doi: 10.1128/mSphere.00346-17. eCollection 2017 Nov-Dec.

15.

MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis.

Menachery VD, Mitchell HD, Cockrell AS, Gralinski LE, Yount BL Jr, Graham RL, McAnarney ET, Douglas MG, Scobey T, Beall A, Dinnon K 3rd, Kocher JF, Hale AE, Stratton KG, Waters KM, Baric RS.

MBio. 2017 Aug 22;8(4). pii: e00665-17. doi: 10.1128/mBio.00665-17.

16.

Efficient Reverse Genetic Systems for Rapid Genetic Manipulation of Emergent and Preemergent Infectious Coronaviruses.

Cockrell AS, Beall A, Yount B, Baric R.

Methods Mol Biol. 2017;1602:59-81. doi: 10.1007/978-1-4939-6964-7_5.

PMID:
28508214
17.

Deletion of a 197-Amino-Acid Region in the N-Terminal Domain of Spike Protein Attenuates Porcine Epidemic Diarrhea Virus in Piglets.

Hou Y, Lin CM, Yokoyama M, Yount BL, Marthaler D, Douglas AL, Ghimire S, Qin Y, Baric RS, Saif LJ, Wang Q.

J Virol. 2017 Jun 26;91(14). pii: e00227-17. doi: 10.1128/JVI.00227-17. Print 2017 Jul 15.

18.

Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus.

Anthony SJ, Gilardi K, Menachery VD, Goldstein T, Ssebide B, Mbabazi R, Navarrete-Macias I, Liang E, Wells H, Hicks A, Petrosov A, Byarugaba DK, Debbink K, Dinnon KH, Scobey T, Randell SH, Yount BL, Cranfield M, Johnson CK, Baric RS, Lipkin WI, Mazet JA.

MBio. 2017 Apr 4;8(2). pii: e00373-17. doi: 10.1128/mBio.00373-17.

19.

A Reverse Genetics Platform That Spans the Zika Virus Family Tree.

Widman DG, Young E, Yount BL, Plante KS, Gallichotte EN, Carbaugh DL, Peck KM, Plante J, Swanstrom J, Heise MT, Lazear HM, Baric RS.

MBio. 2017 Mar 7;8(2). pii: e02014-16. doi: 10.1128/mBio.02014-16.

20.

Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone.

Gallichotte EN, Menachery VD, Yount BL Jr, Widman DG, Dinnon KH 3rd, Hartman S, de Silva AM, Baric RS.

mSphere. 2017 Feb 22;2(1). pii: e00380-16. doi: 10.1128/mSphere.00380-16. eCollection 2017 Jan-Feb.

21.

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome.

Cockrell AS, Yount BL, Scobey T, Jensen K, Douglas M, Beall A, Tang XC, Marasco WA, Heise MT, Baric RS.

Nat Microbiol. 2016 Nov 28;2:16226. doi: 10.1038/nmicrobiol.2016.226.

22.

Corrigendum: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence.

Menachery VD, Yount BL Jr, Debbink K, Agnihothram S, Gralinski LE, Plante JA, Graham RL, Scobey T, Ge XY, Donaldson EF, Randell SH, Lanzavecchia A, Marasco WA, Shi ZL, Baric RS.

Nat Med. 2016 Apr;22(4):446. doi: 10.1038/nm0416-446d. No abstract available.

PMID:
27050591
23.

Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation.

Thornbrough JM, Jha BK, Yount B, Goldstein SA, Li Y, Elliott R, Sims AC, Baric RS, Silverman RH, Weiss SR.

MBio. 2016 Mar 29;7(2):e00258. doi: 10.1128/mBio.00258-16.

24.

SARS-like WIV1-CoV poised for human emergence.

Menachery VD, Yount BL Jr, Sims AC, Debbink K, Agnihothram SS, Gralinski LE, Graham RL, Scobey T, Plante JA, Royal SR, Swanstrom J, Sheahan TP, Pickles RJ, Corti D, Randell SH, Lanzavecchia A, Marasco WA, Baric RS.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3048-53. doi: 10.1073/pnas.1517719113. Epub 2016 Mar 14.

25.

Functional Transplant of a Dengue Virus Serotype 3 (DENV3)-Specific Human Monoclonal Antibody Epitope into DENV1.

Messer WB, Yount BL, Royal SR, de Alwis R, Widman DG, Smith SA, Crowe JE Jr, Pfaff JM, Kahle KM, Doranz BJ, Ibarra KD, Harris E, de Silva AM, Baric RS.

J Virol. 2016 Apr 29;90(10):5090-5097. doi: 10.1128/JVI.00155-16. Print 2016 May 15.

26.

Resolution of diarrhea in an immunocompromised patient with chronic norovirus gastroenteritis correlates with constitution of specific antibody blockade titer.

Knoll BM, Lindesmith LC, Yount BL, Baric RS, Marty FM.

Infection. 2016 Aug;44(4):551-4. doi: 10.1007/s15010-016-0875-1. Epub 2016 Jan 29.

PMID:
26825307
27.

Characterization of a Pathogenic Full-Length cDNA Clone and Transmission Model for Porcine Epidemic Diarrhea Virus Strain PC22A.

Beall A, Yount B, Lin CM, Hou Y, Wang Q, Saif L, Baric R.

MBio. 2016 Jan 5;7(1):e01451-15. doi: 10.1128/mBio.01451-15.

28.

Implications of supermarket access, neighbourhood walkability and poverty rates for diabetes risk in an employee population.

Herrick CJ, Yount BW, Eyler AA.

Public Health Nutr. 2016 Aug;19(11):2040-8. doi: 10.1017/S1368980015003328. Epub 2015 Dec 7.

29.

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence.

Menachery VD, Yount BL Jr, Debbink K, Agnihothram S, Gralinski LE, Plante JA, Graham RL, Scobey T, Ge XY, Donaldson EF, Randell SH, Lanzavecchia A, Marasco WA, Shi ZL, Baric RS.

Nat Med. 2015 Dec;21(12):1508-13. doi: 10.1038/nm.3985. Epub 2015 Nov 9. Erratum in: Nat Med. 2016 Apr;22(4):446.

30.

A new quaternary structure epitope on dengue virus serotype 2 is the target of durable type-specific neutralizing antibodies.

Gallichotte EN, Widman DG, Yount BL, Wahala WM, Durbin A, Whitehead S, Sariol CA, Crowe JE Jr, de Silva AM, Baric RS.

MBio. 2015 Oct 13;6(5):e01461-15. doi: 10.1128/mBio.01461-15.

31.

Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection.

Peck KM, Cockrell AS, Yount BL, Scobey T, Baric RS, Heise MT.

J Virol. 2015 Apr;89(8):4696-9. doi: 10.1128/JVI.03445-14. Epub 2015 Feb 4.

32.

The nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU.

Zhang R, Li Y, Cowley TJ, Steinbrenner AD, Phillips JM, Yount BL, Baric RS, Weiss SR.

J Virol. 2015 Apr;89(7):3598-609. doi: 10.1128/JVI.03535-14. Epub 2015 Jan 14.

33.

A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant.

Agnihothram S, Yount BL Jr, Donaldson EF, Huynh J, Menachery VD, Gralinski LE, Graham RL, Becker MM, Tomar S, Scobey TD, Osswald HL, Whitmore A, Gopal R, Ghosh AK, Mesecar A, Zambon M, Heise M, Denison MR, Baric RS.

MBio. 2014 Mar 25;5(2):e00047-14. doi: 10.1128/mBio.00047-14.

34.

Mouse dipeptidyl peptidase 4 is not a functional receptor for Middle East respiratory syndrome coronavirus infection.

Cockrell AS, Peck KM, Yount BL, Agnihothram SS, Scobey T, Curnes NR, Baric RS, Heise MT.

J Virol. 2014 May;88(9):5195-9. doi: 10.1128/JVI.03764-13. Epub 2014 Feb 26.

35.

Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity.

Menachery VD, Yount BL Jr, Josset L, Gralinski LE, Scobey T, Agnihothram S, Katze MG, Baric RS.

J Virol. 2014 Apr;88(8):4251-64. doi: 10.1128/JVI.03571-13. Epub 2014 Jan 29.

36.

Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity.

Messer WB, de Alwis R, Yount BL, Royal SR, Huynh JP, Smith SA, Crowe JE Jr, Doranz BJ, Kahle KM, Pfaff JM, White LJ, Sariol CA, de Silva AM, Baric RS.

Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1939-44. doi: 10.1073/pnas.1317350111. Epub 2014 Jan 2. Erratum in: Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):6115. Retraction in: Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2738.

37.

A comprehensive collection of systems biology data characterizing the host response to viral infection.

Aevermann BD, Pickett BE, Kumar S, Klem EB, Agnihothram S, Askovich PS, Bankhead A 3rd, Bolles M, Carter V, Chang J, Clauss TR, Dash P, Diercks AH, Eisfeld AJ, Ellis A, Fan S, Ferris MT, Gralinski LE, Green RR, Gritsenko MA, Hatta M, Heegel RA, Jacobs JM, Jeng S, Josset L, Kaiser SM, Kelly S, Law GL, Li C, Li J, Long C, Luna ML, Matzke M, McDermott J, Menachery V, Metz TO, Mitchell H, Monroe ME, Navarro G, Neumann G, Podyminogin RL, Purvine SO, Rosenberger CM, Sanders CJ, Schepmoes AA, Shukla AK, Sims A, Sova P, Tam VC, Tchitchek N, Thomas PG, Tilton SC, Totura A, Wang J, Webb-Robertson BJ, Wen J, Weiss JM, Yang F, Yount B, Zhang Q, McWeeney S, Smith RD, Waters KM, Kawaoka Y, Baric R, Aderem A, Katze MG, Scheuermann RH.

Sci Data. 2014 Oct 14;1:140033. doi: 10.1038/sdata.2014.33. eCollection 2014.

38.

Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses.

Agnihothram S, Gopal R, Yount BL Jr, Donaldson EF, Menachery VD, Graham RL, Scobey TD, Gralinski LE, Denison MR, Zambon M, Baric RS.

J Infect Dis. 2014 Apr 1;209(7):995-1006. doi: 10.1093/infdis/jit609. Epub 2013 Nov 18.

39.

Characterization of blockade antibody responses in GII.2.1976 Snow Mountain virus-infected subjects.

Swanstrom J, Lindesmith LC, Donaldson EF, Yount B, Baric RS.

J Virol. 2014 Jan;88(2):829-37. doi: 10.1128/JVI.02793-13. Epub 2013 Oct 30.

40.

Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus.

Scobey T, Yount BL, Sims AC, Donaldson EF, Agnihothram SS, Menachery VD, Graham RL, Swanstrom J, Bove PF, Kim JD, Grego S, Randell SH, Baric RS.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16157-62. doi: 10.1073/pnas.1311542110. Epub 2013 Sep 16.

41.

Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus.

Josset L, Menachery VD, Gralinski LE, Agnihothram S, Sova P, Carter VS, Yount BL, Graham RL, Baric RS, Katze MG.

MBio. 2013 Apr 30;4(3):e00165-13. doi: 10.1128/mBio.00165-13.

42.

The mechanism of differential neutralization of dengue serotype 3 strains by monoclonal antibody 8A1.

Zhou Y, Austin SK, Fremont DH, Yount BL, Huynh JP, de Silva AM, Baric RS, Messer WB.

Virology. 2013 Apr 25;439(1):57-64. doi: 10.1016/j.virol.2013.01.022. Epub 2013 Feb 28.

43.

RNA dimerization plays a role in ribosomal frameshifting of the SARS coronavirus.

Ishimaru D, Plant EP, Sims AC, Yount BL Jr, Roth BM, Eldho NV, Pérez-Alvarado GC, Armbruster DW, Baric RS, Dinman JD, Taylor DR, Hennig M.

Nucleic Acids Res. 2013 Feb 1;41(4):2594-608. doi: 10.1093/nar/gks1361. Epub 2012 Dec 28.

44.

Evidence supporting a zoonotic origin of human coronavirus strain NL63.

Huynh J, Li S, Yount B, Smith A, Sturges L, Olsen JC, Nagel J, Johnson JB, Agnihothram S, Gates JE, Frieman MB, Baric RS, Donaldson EF.

J Virol. 2012 Dec;86(23):12816-25. doi: 10.1128/JVI.00906-12. Epub 2012 Sep 19.

45.

Factors influencing the implementation of school wellness policies in the United States, 2009.

Budd EL, Schwarz C, Yount BW, Haire-Joshu D.

Prev Chronic Dis. 2012;9:E118. Epub 2012 Jun 28.

46.

Development and characterization of a reverse genetic system for studying dengue virus serotype 3 strain variation and neutralization.

Messer WB, Yount B, Hacker KE, Donaldson EF, Huynh JP, de Silva AM, Baric RS.

PLoS Negl Trop Dis. 2012;6(2):e1486. doi: 10.1371/journal.pntd.0001486. Epub 2012 Feb 28.

47.

Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease.

Frieman M, Yount B, Agnihothram S, Page C, Donaldson E, Roberts A, Vogel L, Woodruff B, Scorpio D, Subbarao K, Baric RS.

J Virol. 2012 Jan;86(2):884-97. doi: 10.1128/JVI.05957-11. Epub 2011 Nov 9.

48.

The quality of school wellness policies and energy-balance behaviors of adolescent mothers.

Haire-Joshu D, Yount BW, Budd EL, Schwarz C, Schermbeck R, Green S, Elliott M.

Prev Chronic Dis. 2011 Mar;8(2):A34. Epub 2011 Feb 15.

49.

Postpartum teens' breakfast consumption is associated with snack and beverage intake and body mass index.

Haire-Joshu D, Schwarz C, Budd E, Yount BW, Lapka C.

J Am Diet Assoc. 2011 Jan;111(1):124-30. doi: 10.1016/j.jada.2010.10.009.

50.

Parks promoting physical activity: synthesis of findings from interventions in seven national parks.

Hoehner CM, Brownson RC, Allen D, Gramann J, Behrens TK, Floyd MF, Leahy J, Liddle JB, Smaldone D, Spain DD, Tardona DR, Ruthmann NP, Seiler RL, Yount BW.

J Phys Act Health. 2010 Mar;7 Suppl 1:S67-81.

PMID:
20440015

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