Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 65


Leveraging Advanced Practice Nursing in Complex Health Care Systems.

Younger SJ.

Nurs Adm Q. 2020 Apr/Jun;44(2):127-135. doi: 10.1097/NAQ.0000000000000408.


Identification of functional regulatory elements in the human genome using pooled CRISPR screens.

Borys SM, Younger ST.

BMC Genomics. 2020 Jan 31;21(1):107. doi: 10.1186/s12864-020-6497-0.


Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets.

Dempster JM, Pacini C, Pantel S, Behan FM, Green T, Krill-Burger J, Beaver CM, Younger ST, Zhivich V, Najgebauer H, Allen F, Gonçalves E, Shepherd R, Doench JG, Yusa K, Vazquez F, Parts L, Boehm JS, Golub TR, Hahn WC, Root DE, Garnett MJ, Tsherniak A, Iorio F.

Nat Commun. 2019 Dec 20;10(1):5817. doi: 10.1038/s41467-019-13805-y.


Wetness index based on landscape position and topography (WILT): Modifying TWI to reflect landscape position.

Meles MB, Younger SE, Jackson CR, Du E, Drover D.

J Environ Manage. 2020 Feb 1;255:109863. doi: 10.1016/j.jenvman.2019.109863. Epub 2019 Nov 29.


Effects of chronic exposure to a mixed field of neutrons and photons on behavioral and cognitive performance in mice.

Perez RE, Younger S, Bertheau E, Fallgren CM, Weil MM, Raber J.

Behav Brain Res. 2020 Feb 3;379:112377. doi: 10.1016/j.bbr.2019.112377. Epub 2019 Nov 22.


Paralytic, the Drosophila voltage-gated sodium channel, regulates proliferation of neural progenitors.

Piggott BJ, Peters CJ, He Y, Huang X, Younger S, Jan LY, Jan YN.

Genes Dev. 2019 Dec 1;33(23-24):1739-1750. doi: 10.1101/gad.330597.119. Epub 2019 Nov 21.


Glial ensheathment of the somatodendritic compartment regulates sensory neuron structure and activity.

Yadav S, Younger SH, Zhang L, Thompson-Peer KL, Li T, Jan LY, Jan YN.

Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5126-5134. doi: 10.1073/pnas.1814456116. Epub 2019 Feb 25.


Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.

Harris IS, Endress JE, Coloff JL, Selfors LM, McBrayer SK, Rosenbluth JM, Takahashi N, Dhakal S, Koduri V, Oser MG, Schauer NJ, Doherty LM, Hong AL, Kang YP, Younger ST, Doench JG, Hahn WC, Buhrlage SJ, DeNicola GM, Kaelin WG Jr, Brugge JS.

Cell Metab. 2019 May 7;29(5):1166-1181.e6. doi: 10.1016/j.cmet.2019.01.020. Epub 2019 Feb 21.


Microbial Degradation of Epoxy.

Eliaz N, Ron EZ, Gozin M, Younger S, Biran D, Tal N.

Materials (Basel). 2018 Oct 29;11(11). pii: E2123. doi: 10.3390/ma11112123.


Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival.

Oser MG, Fonseca R, Chakraborty AA, Brough R, Spektor A, Jennings RB, Flaifel A, Novak JS, Gulati A, Buss E, Younger ST, McBrayer SK, Cowley GS, Bonal DM, Nguyen QD, Brulle-Soumare L, Taylor P, Cairo S, Ryan CJ, Pease EJ, Maratea K, Travers J, Root DE, Signoretti S, Pellman D, Ashton S, Lord CJ, Barry ST, Kaelin WG Jr.

Cancer Discov. 2019 Feb;9(2):230-247. doi: 10.1158/2159-8290.CD-18-0389. Epub 2018 Oct 29.


Pooled Lentiviral-Delivery Genetic Screens.

Piccioni F, Younger ST, Root DE.

Curr Protoc Mol Biol. 2018 Jan 16;121:32.1.1-32.1.21. doi: 10.1002/cpmb.52.


Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens.

Najm FJ, Strand C, Donovan KF, Hegde M, Sanson KR, Vaimberg EW, Sullender ME, Hartenian E, Kalani Z, Fusi N, Listgarten J, Younger ST, Bernstein BE, Root DE, Doench JG.

Nat Biotechnol. 2018 Feb;36(2):179-189. doi: 10.1038/nbt.4048. Epub 2017 Dec 18.


Fiscal Incidence in Ghana.

Younger SD, Osei-Assibey E, Oppong F.

Rev Dev Econ. 2017 Nov;21(4):e47-e66. doi: 10.1111/rode.12299. Epub 2017 Jan 11.


p53 regulates enhancer accessibility and activity in response to DNA damage.

Younger ST, Rinn JL.

Nucleic Acids Res. 2017 Sep 29;45(17):9889-9900. doi: 10.1093/nar/gkx577.


PINK1 Is a Negative Regulator of Growth and the Warburg Effect in Glioblastoma.

Agnihotri S, Golbourn B, Huang X, Remke M, Younger S, Cairns RA, Chalil A, Smith CA, Krumholtz SL, Mackenzie D, Rakopoulos P, Ramaswamy V, Taccone MS, Mischel PS, Fuller GN, Hawkins C, Stanford WL, Taylor MD, Zadeh G, Rutka JT.

Cancer Res. 2016 Aug 15;76(16):4708-19. doi: 10.1158/0008-5472.CAN-15-3079. Epub 2016 Jun 20.


Epidermis-Derived Semaphorin Promotes Dendrite Self-Avoidance by Regulating Dendrite-Substrate Adhesion in Drosophila Sensory Neurons.

Meltzer S, Yadav S, Lee J, Soba P, Younger SH, Jin P, Zhang W, Parrish J, Jan LY, Jan YN.

Neuron. 2016 Feb 17;89(4):741-55. doi: 10.1016/j.neuron.2016.01.020. Epub 2016 Feb 4.


Silent pericentromeric repeats speak out.

Younger ST, Rinn JL.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15008-9. doi: 10.1073/pnas.1520341112. Epub 2015 Nov 18. No abstract available.


EAG2 potassium channel with evolutionarily conserved function as a brain tumor target.

Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, Garzia L, Wu X, Remke M, Forester CM, Kim CC, Weiss WA, James CD, Shuman MA, Bader GD, Mueller S, Taylor MD, Jan YN, Jan LY.

Nat Neurosci. 2015 Sep;18(9):1236-46. doi: 10.1038/nn.4088. Epub 2015 Aug 10.


Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display.

Shechner DM, Hacisuleyman E, Younger ST, Rinn JL.

Nat Methods. 2015 Jul;12(7):664-70. doi: 10.1038/nmeth.3433. Epub 2015 Jun 1.


Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage.

Younger ST, Kenzelmann-Broz D, Jung H, Attardi LD, Rinn JL.

Nucleic Acids Res. 2015 May 19;43(9):4447-62. doi: 10.1093/nar/gkv284. Epub 2015 Apr 16.


Identification of Ppk26, a DEG/ENaC Channel Functioning with Ppk1 in a Mutually Dependent Manner to Guide Locomotion Behavior in Drosophila.

Gorczyca DA, Younger S, Meltzer S, Kim SE, Cheng L, Song W, Lee HY, Jan LY, Jan YN.

Cell Rep. 2014 Nov 20;9(4):1446-58. doi: 10.1016/j.celrep.2014.10.034. Epub 2014 Nov 6.


Identification and validation of miRNA target sites within nontraditional miRNA targets.

Younger ST, Corey DR.

Methods Mol Biol. 2015;1206:53-67. doi: 10.1007/978-1-4939-1369-5_5.


'Lnc'-ing enhancers to MYC regulation.

Younger ST, Rinn JL.

Cell Res. 2014 Jun;24(6):643-4. doi: 10.1038/cr.2014.54. Epub 2014 Apr 29.


Subdued, a TMEM16 family Ca²⁺-activated Cl⁻channel in Drosophila melanogaster with an unexpected role in host defense.

Wong XM, Younger S, Peters CJ, Jan YN, Jan LY.

Elife. 2013 Nov 5;2:e00862. doi: 10.7554/eLife.00862.


The bHLH repressor Deadpan regulates the self-renewal and specification of Drosophila larval neural stem cells independently of Notch.

Zhu S, Wildonger J, Barshow S, Younger S, Huang Y, Lee T.

PLoS One. 2012;7(10):e46724. doi: 10.1371/journal.pone.0046724. Epub 2012 Oct 8.


Transcriptional regulation by miRNA mimics that target sequences downstream of gene termini.

Younger ST, Corey DR.

Mol Biosyst. 2011 Aug;7(8):2383-8. doi: 10.1039/c1mb05090g. Epub 2011 May 18.


Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters.

Younger ST, Corey DR.

Nucleic Acids Res. 2011 Jul;39(13):5682-91. doi: 10.1093/nar/gkr155. Epub 2011 Mar 22.


Differential regulation of dendritic and axonal development by the novel Krüppel-like factor Dar1.

Ye B, Kim JH, Yang L, McLachlan I, Younger S, Jan LY, Jan YN.

J Neurosci. 2011 Mar 2;31(9):3309-19. doi: 10.1523/JNEUROSCI.6307-10.2011.


Order of functionality loss during photodegradation of aquatic humic substances.

Thorn KA, Younger SJ, Cox LG.

J Environ Qual. 2010 Jul-Aug;39(4):1416-28.


Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter.

Chu Y, Yue X, Younger ST, Janowski BA, Corey DR.

Nucleic Acids Res. 2010 Nov;38(21):7736-48. doi: 10.1093/nar/gkq648. Epub 2010 Jul 30.


Transcriptional regulation by small RNAs at sequences downstream from 3' gene termini.

Yue X, Schwartz JC, Chu Y, Younger ST, Gagnon KT, Elbashir S, Janowski BA, Corey DR.

Nat Chem Biol. 2010 Aug;6(8):621-9. doi: 10.1038/nchembio.400. Epub 2010 Jun 27.


Predicting potential miRNA target sites within gene promoters.

Younger ST, Pertsemlidis A, Corey DR.

Bioorg Med Chem Lett. 2009 Jul 15;19(14):3791-4. doi: 10.1016/j.bmcl.2009.04.032. Epub 2009 Apr 18.


The puzzle of RNAs that target gene promoters.

Younger ST, Corey DR.

Chembiochem. 2009 May 4;10(7):1135-9. doi: 10.1002/cbic.200900015.


Measuring intra-household health inequality: explorations using the body mass index.

Sahn DE, Younger SD.

Health Econ. 2009 Apr;18 Suppl 1:S13-36. doi: 10.1002/hec.1459.


Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons.

Zheng Y, Wildonger J, Ye B, Zhang Y, Kita A, Younger SH, Zimmerman S, Jan LY, Jan YN.

Nat Cell Biol. 2008 Oct;10(10):1172-80. doi: 10.1038/ncb1777. Epub 2008 Aug 31.


Antisense transcripts are targets for activating small RNAs.

Schwartz JC, Younger ST, Nguyen NB, Hardy DB, Monia BP, Corey DR, Janowski BA.

Nat Struct Mol Biol. 2008 Aug;15(8):842-8. doi: 10.1038/nsmb.1444. Epub 2008 Jul 6.


Growing dendrites and axons differ in their reliance on the secretory pathway.

Ye B, Zhang Y, Song W, Younger SH, Jan LY, Jan YN.

Cell. 2007 Aug 24;130(4):717-29.


Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization.

Soba P, Zhu S, Emoto K, Younger S, Yang SJ, Yu HH, Lee T, Jan LY, Jan YN.

Neuron. 2007 May 3;54(3):403-16.


Activating gene expression in mammalian cells with promoter-targeted duplex RNAs.

Janowski BA, Younger ST, Hardy DB, Ram R, Huffman KE, Corey DR.

Nat Chem Biol. 2007 Mar;3(3):166-73. Epub 2007 Jan 28.


Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology.

Grueber WB, Ye B, Yang CH, Younger S, Borden K, Jan LY, Jan YN.

Development. 2007 Jan;134(1):55-64.


The "seesaw" sign: improved sonographic identification of the sciatic nerve.

Schafhalter-Zoppoth I, Younger SJ, Collins AB, Gray AT.

Anesthesiology. 2004 Sep;101(3):808-9. No abstract available. Erratum in: Anesthesiology. 2005 Jan;102(1):248.


Immunologic and virologic evolution during periods of intermittent and persistent low-level viremia.

Karlsson AC, Younger SR, Martin JN, Grossman Z, Sinclair E, Hunt PW, Hagos E, Nixon DF, Deeks SG.

AIDS. 2004 Apr 30;18(7):981-9.


Comparison of the ELISPOT and cytokine flow cytometry assays for the enumeration of antigen-specific T cells.

Karlsson AC, Martin JN, Younger SR, Bredt BM, Epling L, Ronquillo R, Varma A, Deeks SG, McCune JM, Nixon DF, Sinclair E.

J Immunol Methods. 2003 Dec;283(1-2):141-53.


Dual pressure from antiretroviral therapy and cell-mediated immune response on the human immunodeficiency virus type 1 protease gene.

Karlsson AC, Deeks SG, Barbour JD, Heiken BD, Younger SR, Hoh R, Lane M, Sällberg M, Ortiz GM, Demarest JF, Liegler T, Grant RM, Martin JN, Nixon DF.

J Virol. 2003 Jun;77(12):6743-52.


Decomposing world health inequality.

Pradhan M, Sahn DE, Younger SD.

J Health Econ. 2003 Mar;22(2):271-93.


Transgenic inhibitors identify two roles for protein kinase A in Drosophila development.

Kiger JA Jr, Eklund JL, Younger SH, O'Kane CJ.

Genetics. 1999 May;152(1):281-90.


Target Plasma Formation for Magnetic Compression/Magnetized Target Fusion.

Lindemuth IR, Reinovsky RE, Chrien RE, Christian JM, Ekdahl CA, Goforth JH, Haight RC, Idzorek G, King NS, Kirkpatrick RC, Larson RE, Morgan GL, Olinger BW, Oona H, Sheehey PT, Shlachter JS, Smith RC, Veeser LR, Warthen BJ, Younger SM, Chernyshev VK, Mokhov VN, Demin AN, Dolin YN, Garanin SF, Ivanov VA, Korchagin VP, Mikhailov OD, Morozov IV IV, Pak SV, Pavlovskii ES, Seleznev NY, Skobelev AN, Volkov GI, Yakubov VA.

Phys Rev Lett. 1995 Sep 4;75(10):1953-1956. No abstract available.


Research priorities for all phases of postanesthesia nursing: a survey by ASPAN.

Heffline MS, Clark ML, Hooper VD, Mamaril M, Miller KM, Norris S, Poole EL, Summers S, Younger S.

J Post Anesth Nurs. 1994 Aug;9(4):204-13.


Supplemental Content

Loading ...
Support Center