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Rapid, Reproducible, Quantifiable NMR Metabolomics: Methanol and Methanol: Chloroform Precipitation for Removal of Macromolecules in Serum and Whole Blood.

McHugh CE, Flott TL, Schooff CR, Smiley Z, Puskarich MA, Myers DD, Younger JG, Jones AE, Stringer KA.

Metabolites. 2018 Dec 14;8(4). pii: E93. doi: 10.3390/metabo8040093.


Effect of Antimicrobial and Physical Treatments on Growth of Multispecies Staphylococcal Biofilms.

Stewart EJ, Payne DE, Ma TM, VanEpps JS, Boles BR, Younger JG, Solomon MJ.

Appl Environ Microbiol. 2017 May 31;83(12). pii: e03483-16. doi: 10.1128/AEM.03483-16. Print 2017 Jun 15.


A Cationic Amphiphilic Random Copolymer with pH-Responsive Activity against Methicillin-Resistant Staphylococcus aureus.

Hong S, Takahashi H, Nadres ET, Mortazavian H, Caputo GA, Younger JG, Kuroda K.

PLoS One. 2017 Jan 6;12(1):e0169262. doi: 10.1371/journal.pone.0169262. eCollection 2017.


Making Improvements in the ED: Does ED Busyness Affect Time to Antibiotics in Febrile Pediatric Oncology Patients Presenting to the Emergency Department?

Benner CA, Mora E, Mueller E, Seagull FJ, Walkovich K, Johnson K, Halverson S, Rothman E, Hucks G, Younger JG, Nypaver MM.

Pediatr Emerg Care. 2018 May;34(5):310-316. doi: 10.1097/PEC.0000000000000882.


Implantable Device-Related Infection.

VanEpps JS, Younger JG.

Shock. 2016 Dec;46(6):597-608. Review.


Zinc oxide nanoparticle suspensions and layer-by-layer coatings inhibit staphylococcal growth.

McGuffie MJ, Hong J, Bahng JH, Glynos E, Green PF, Kotov NA, Younger JG, VanEpps JS.

Nanomedicine. 2016 Jan;12(1):33-42. doi: 10.1016/j.nano.2015.10.002. Epub 2015 Oct 27.


Hemodialysis Catheter Heat Transfer for Biofilm Prevention and Treatment.

Richardson IP, Sturtevant R, Heung M, Solomon MJ, Younger JG, VanEpps JS.

ASAIO J. 2016 Jan-Feb;62(1):92-9. doi: 10.1097/MAT.0000000000000300.


Artificial biofilms establish the role of matrix interactions in staphylococcal biofilm assembly and disassembly.

Stewart EJ, Ganesan M, Younger JG, Solomon MJ.

Sci Rep. 2015 Aug 14;5:13081. doi: 10.1038/srep13081.


Whole Blood Reveals More Metabolic Detail of the Human Metabolome than Serum as Measured by 1H-NMR Spectroscopy: Implications for Sepsis Metabolomics.

Stringer KA, Younger JG, McHugh C, Yeomans L, Finkel MA, Puskarich MA, Jones AE, Trexel J, Karnovsky A.

Shock. 2015 Sep;44(3):200-8. doi: 10.1097/SHK.0000000000000406.


Thermal Augmentation of Vancomycin Against Staphylococcal Biofilms.

Sturtevant RA, Sharma P, Pavlovsky L, Stewart EJ, Solomon MJ, Younger JG.

Shock. 2015 Aug;44(2):121-7. doi: 10.1097/SHK.0000000000000369.


Effects of temperature on the morphological, polymeric, and mechanical properties of Staphylococcus epidermidis bacterial biofilms.

Pavlovsky L, Sturtevant RA, Younger JG, Solomon MJ.

Langmuir. 2015 Feb 17;31(6):2036-42. doi: 10.1021/la5044156. Epub 2015 Feb 2.


Elasticity of microscale volumes of viscoelastic soft matter by cavitation rheometry.

Pavlovsky L, Ganesan M, Younger JG, Solomon MJ.

Appl Phys Lett. 2014 Sep 15;105(11):114105.


Sticky surface: sphere-sphere adhesion dynamics.

Sircar S, Younger JG, Bortz DM.

J Biol Dyn. 2015;9 Suppl 1:79-89. doi: 10.1080/17513758.2014.942394. Epub 2014 Aug 27.


Multilocus Sequence Typing for Interpreting Blood Isolates of Staphylococcus epidermidis.

Sharma P, Satorius AE, Raff MR, Rivera A, Newton DW, Younger JG.

Interdiscip Perspect Infect Dis. 2014;2014:787458. doi: 10.1155/2014/787458. Epub 2014 Mar 2.


Characterization of a reverse-phase perfluorocarbon emulsion for the pulmonary delivery of tobramycin.

Orizondo RA, Babcock CI, Fabiilli ML, Pavlovsky L, Fowlkes JB, Younger JG, Cook KE.

J Aerosol Med Pulm Drug Deliv. 2014 Oct;27(5):392-9. doi: 10.1089/jamp.2013.1058. Epub 2014 Jan 29.


What's new in Shock? January 2014.

Younger JG.

Shock. 2014 Jan;41(1):1-2. doi: 10.1097/SHK.0000000000000084. No abstract available.


Prospective comparison of live evaluation and video review in the evaluation of operator performance in a pediatric emergency airway simulation.

House JB, Dooley-Hash S, Kowalenko T, Sikavitsas A, Seeyave DM, Younger JG, Hamstra SJ, Nypaver MM.

J Grad Med Educ. 2012 Sep;4(3):312-6. doi: 10.4300/JGME-D-11-00123.1.


Role of environmental and antibiotic stress on Staphylococcus epidermidis biofilm microstructure.

Stewart EJ, Satorius AE, Younger JG, Solomon MJ.

Langmuir. 2013 Jun 11;29(23):7017-24. doi: 10.1021/la401322k. Epub 2013 May 31.


Molar mass, entanglement, and associations of the biofilm polysaccharide of Staphylococcus epidermidis.

Ganesan M, Stewart EJ, Szafranski J, Satorius AE, Younger JG, Solomon MJ.

Biomacromolecules. 2013 May 13;14(5):1474-81. doi: 10.1021/bm400149a. Epub 2013 Apr 17.


Impact of hourly emergency department patient volume on blood culture contamination and diagnostic yield.

Halverson S, Malani PN, Newton DW, Habicht A, Vander Have K, Younger JG.

J Clin Microbiol. 2013 Jun;51(6):1721-6. doi: 10.1128/JCM.03422-12. Epub 2013 Mar 20.


Complement c5a generation by staphylococcal biofilms.

Satorius AE, Szafranski J, Pyne D, Ganesan M, Solomon MJ, Newton DW, Bortz DM, Younger JG.

Shock. 2013 Apr;39(4):336-42. doi: 10.1097/SHK.0b013e31828d9324.


Spatiotemporal dynamics of complement C5a production within bacterial extracellular polymeric substance.

Conrad EC, Hsu YY, Bortz DM, Younger JG.

J Innate Immun. 2013;5(2):114-23. doi: 10.1159/000345705. Epub 2013 Jan 11.


In situ rheology of Staphylococcus epidermidis bacterial biofilms.

Pavlovsky L, Younger JG, Solomon MJ.

Soft Matter. 2013 Jan 7;9(1):122-131.


Early development of bacterial community diversity in emergently placed urinary catheters.

Foxman B, Wu J, Farrer EC, Goldberg DE, Younger JG, Xi C.

BMC Res Notes. 2012 Jun 27;5:332. doi: 10.1186/1756-0500-5-332.


Multicellularity and antibiotic resistance in Klebsiella pneumoniae grown under bloodstream-mimicking fluid dynamic conditions.

Thornton MM, Chung-Esaki HM, Irvin CB, Bortz DM, Solomon MJ, Younger JG.

J Infect Dis. 2012 Aug 15;206(4):588-95. doi: 10.1093/infdis/jis397. Epub 2012 Jun 18.


Early career academic productivity among emergency physicians with R01 grant funding.

Scott Van Epps J, Younger JG.

Acad Emerg Med. 2011 Jul;18(7):759-62. doi: 10.1111/j.1553-2712.2011.01118.x.


A prospective study of central venous catheters placed in a tertiary care Emergency Department: indications for use, infectious complications, and natural history.

Diaz K, Kelly SG, Smith B, Malani PN, Younger JG.

Am J Infect Control. 2012 Feb;40(1):65-7. doi: 10.1016/j.ajic.2011.03.018. Epub 2011 Jul 8.


Diabetes is not associated with increased mortality in emergency department patients with sepsis.

Schuetz P, Jones AE, Howell MD, Trzeciak S, Ngo L, Younger JG, Aird W, Shapiro NI.

Ann Emerg Med. 2011 Nov;58(5):438-44. doi: 10.1016/j.annemergmed.2011.03.052. Epub 2011 Jun 16.


Contribution of the Klebsiella pneumoniae capsule to bacterial aggregate and biofilm microstructures.

Dzul SP, Thornton MM, Hohne DN, Stewart EJ, Shah AA, Bortz DM, Solomon MJ, Younger JG.

Appl Environ Microbiol. 2011 Mar;77(5):1777-82. doi: 10.1128/AEM.01752-10. Epub 2011 Jan 14.


Prospective trial of real-time electronic surveillance to expedite early care of severe sepsis.

Nelson JL, Smith BL, Jared JD, Younger JG.

Ann Emerg Med. 2011 May;57(5):500-4. doi: 10.1016/j.annemergmed.2010.12.008. Epub 2011 Jan 12.


Short-term functional decline of older adults admitted for suspected sepsis.

Meurer WJ, Losman ED, Smith BL, Malani PN, Younger JG.

Am J Emerg Med. 2011 Oct;29(8):936-42. doi: 10.1016/j.ajem.2010.04.003. Epub 2010 Jul 13.


Complement activation in emergency department patients with severe sepsis.

Younger JG, Bracho DO, Chung-Esaki HM, Lee M, Rana GK, Sen A, Jones AE.

Acad Emerg Med. 2010 Apr;17(4):353-9. doi: 10.1111/j.1553-2712.2010.00713.x.


Accuracy of non-contact infrared thermometry versus rectal thermometry in young children evaluated in the emergency department for fever.

Fortuna EL, Carney MM, Macy M, Stanley RM, Younger JG, Bradin SA.

J Emerg Nurs. 2010 Mar;36(2):101-4. doi: 10.1016/j.jen.2009.07.017. Epub 2009 Sep 3.


Dynamics of human complement-mediated killing of Klebsiella pneumoniae.

Nypaver CM, Thornton MM, Yin SM, Bracho DO, Nelson PW, Jones AE, Bortz DM, Younger JG.

Am J Respir Cell Mol Biol. 2010 Nov;43(5):585-90. doi: 10.1165/rcmb.2009-0292OC. Epub 2009 Dec 11.


Factors associated with survival in infants with congenital diaphragmatic hernia requiring extracorporeal membrane oxygenation: a report from the Congenital Diaphragmatic Hernia Study Group.

Seetharamaiah R, Younger JG, Bartlett RH, Hirschl RB; Congenital Diaphragmatic Hernia Study Group.

J Pediatr Surg. 2009 Jul;44(7):1315-21. doi: 10.1016/j.jpedsurg.2008.12.021.


Antibacterial properties of an iron-based hemostatic agent in vitro and in a rat wound model.

Bracho DO, Barsan L, Arekapudi SR, Thompson JA, Hen J, Stern SA, Younger JG.

Acad Emerg Med. 2009 Jul;16(7):656-60. doi: 10.1111/j.1553-2712.2009.00439.x. Epub 2009 Jun 15.


Flexible microfluidic device for mechanical property characterization of soft viscoelastic solids such as bacterial biofilms.

Hohne DN, Younger JG, Solomon MJ.

Langmuir. 2009 Jul 7;25(13):7743-51. doi: 10.1021/la803413x.


Forecasting models of emergency department crowding.

Schweigler LM, Desmond JS, McCarthy ML, Bukowski KJ, Ionides EL, Younger JG.

Acad Emerg Med. 2009 Apr;16(4):301-8. doi: 10.1111/j.1553-2712.2009.00356.x. Epub 2009 Feb 4.


Real-time identification of serious infection in geriatric patients using clinical information system surveillance.

Meurer WJ, Smith BL, Losman ED, Sherman D, Yaksich JD, Jared JD, Malani PN, Younger JG.

J Am Geriatr Soc. 2009 Jan;57(1):40-5. doi: 10.1111/j.1532-5415.2008.02094.x.


Dynamical system analysis of Staphylococcus epidermidis bloodstream infection.

Chung HM, Cartwright MM, Bortz DM, Jackson TL, Younger JG.

Shock. 2008 Nov;30(5):518-26. doi: 10.1097/SHK.0b013e31816a0b77.


Klebsiella pneumoniae flocculation dynamics.

Bortz DM, Jackson TL, Taylor KA, Thompson AP, Younger JG.

Bull Math Biol. 2008 Apr;70(3):745-68. Epub 2007 Dec 11.


In vitro and in silico analysis of annexin V binding to lymphocytes as a biomarker in emergency department sepsis studies.

Greineder CF, Nelson PW, Dressel AL, Erba HP, Younger JG.

Acad Emerg Med. 2007 Sep;14(9):763-71. Epub 2007 Apr 26.


Lipopolysaccharide O-antigen promotes persistent murine bacteremia.

Lugo JZ, Price S, Miller JE, Ben-David I, Merrill V, Mancuso P, Weinberg JB, Younger JG.

Shock. 2007 Feb;27(2):186-91. Erratum in: Shock. 2008 Jul;30(1): 102.. Merrill, Vija J [corrected to Merrill, Vija A]..


Generation of C5a in the absence of C3: a new complement activation pathway.

Huber-Lang M, Sarma JV, Zetoune FS, Rittirsch D, Neff TA, McGuire SR, Lambris JD, Warner RL, Flierl MA, Hoesel LM, Gebhard F, Younger JG, Drouin SM, Wetsel RA, Ward PA.

Nat Med. 2006 Jun;12(6):682-7. Epub 2006 May 21.


Intracerebral hemorrhage in complement C3-deficient mice.

Yang S, Nakamura T, Hua Y, Keep RF, Younger JG, Hoff JT, Xi G.

Acta Neurochir Suppl. 2006;96:227-31.


The role of complement C3 in intracerebral hemorrhage-induced brain injury.

Yang S, Nakamura T, Hua Y, Keep RF, Younger JG, He Y, Hoff JT, Xi G.

J Cereb Blood Flow Metab. 2006 Dec;26(12):1490-5. Epub 2006 Mar 22.


Management of emergencies in critical care.

Barsan W, Younger JG.

Semin Respir Crit Care Med. 2002 Feb;23(1):1-2. No abstract available.


Acute respiratory infection with mouse adenovirus type 1.

Weinberg JB, Stempfle GS, Wilkinson JE, Younger JG, Spindler KR.

Virology. 2005 Sep 30;340(2):245-54.


Dynamics of intrapulmonary bacterial growth in a murine model of repeated microaspiration.

Ben-David I, Price SE, Bortz DM, Greineder CF, Cohen SE, Bauer AL, Jackson TL, Younger JG.

Am J Respir Cell Mol Biol. 2005 Nov;33(5):476-82. Epub 2005 Jul 13.


Harmful and protective roles of neutrophils in sepsis.

Hoesel LM, Neff TA, Neff SB, Younger JG, Olle EW, Gao H, Pianko MJ, Bernacki KD, Sarma JV, Ward PA.

Shock. 2005 Jul;24(1):40-7.


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