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Items: 1 to 50 of 258

1.

The effects of sprint training and the Nordic hamstring exercise on eccentric hamstring strength and sprint performance in adolescent athletes.

Freeman BW, Young WB, Talpey SW, Smyth AM, Pane CL, Carlon TA.

J Sports Med Phys Fitness. 2019 Jul;59(7):1119-1125. doi: 10.23736/S0022-4707.18.08703-0.

PMID:
31332988
2.

Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice.

Dash PK, Kaminski R, Bella R, Su H, Mathews S, Ahooyi TM, Chen C, Mancuso P, Sariyer R, Ferrante P, Donadoni M, Robinson JA, Sillman B, Lin Z, Hilaire JR, Banoub M, Elango M, Gautam N, Mosley RL, Poluektova LY, McMillan J, Bade AN, Gorantla S, Sariyer IK, Burdo TH, Young WB, Amini S, Gordon J, Jacobson JM, Edagwa B, Khalili K, Gendelman HE.

Nat Commun. 2019 Jul 2;10(1):2753. doi: 10.1038/s41467-019-10366-y.

3.

Efficacy of Combined General, Special, and Specific Resistance Training on Pace Bowling Skill in Club-Standard Cricketers.

Feros SA, Young WB, OʼBrien BJ.

J Strength Cond Res. 2019 Feb 6. doi: 10.1519/JSC.0000000000002940. [Epub ahead of print]

PMID:
30741863
4.

Migraine: Stigma in Society.

Parikh SK, Young WB.

Curr Pain Headache Rep. 2019 Feb 9;23(1):8. doi: 10.1007/s11916-019-0743-7. Review.

PMID:
30739216
5.

Effects of onabotulinumtoxinA treatment in chronic migraine patients with and without daily headache at baseline: results from the COMPEL Study.

Young WB, Ivan Lopez J, Rothrock JF, Orejudos A, Manack Adams A, Lipton RB, Blumenfeld AM.

J Headache Pain. 2019 Feb 1;20(1):12. doi: 10.1186/s10194-018-0953-0.

6.

Effects of onabotulinumtoxinA treatment in patients with and without allodynia: results of the COMPEL study.

Young WB, Ivan Lopez J, Rothrock JF, Orejudos A, Manack Adams A, Lipton RB, Blumenfeld AM.

J Headache Pain. 2019 Jan 22;20(1):10. doi: 10.1186/s10194-018-0952-1.

7.

The Effect of Onabotulinum Toxin on Aura Frequency and Severity in Patients With Hemiplegic Migraine - A Comment.

Young WB.

Headache. 2019 Jan;59(1):110. doi: 10.1111/head.13445. No abstract available.

PMID:
30575970
8.

Removal of HIV DNA by CRISPR from Patient Blood Engrafts in Humanized Mice.

Bella R, Kaminski R, Mancuso P, Young WB, Chen C, Sariyer R, Fischer T, Amini S, Ferrante P, Jacobson JM, Kashanchi F, Khalili K.

Mol Ther Nucleic Acids. 2018 Sep 7;12:275-282. doi: 10.1016/j.omtn.2018.05.021. Epub 2018 Jun 19.

9.

Sex and Gender Differences in Migraine-Evaluating Knowledge Gaps.

Schroeder RA, Brandes J, Buse DC, Calhoun A, Eikermann-Haerter K, Golden K, Halker R, Kempner J, Maleki N, Moriarty M, Pavlovic J, Shapiro RE, Starling A, Young WB, Nebel RA.

J Womens Health (Larchmt). 2018 Aug;27(8):965-973. doi: 10.1089/jwh.2018.7274.

PMID:
30129895
10.

Association Between Pre-season Training and Performance in Elite Australian Football.

McCaskie CJ, Young WB, Fahrner BB, Sim M.

Int J Sports Physiol Perform. 2018 Aug 17:1-25. doi: 10.1123/ijspp.2018-0076. [Epub ahead of print]

PMID:
30117344
11.

Gradual vs. Maximal Acceleration: Their Influence on the Prescription of Maximal Speed Sprinting in Team Sport Athletes.

Young WB, Duthie GM, James LP, Talpey SW, Benton DT, Kilfoyle A.

Sports (Basel). 2018 Jul 21;6(3). pii: E66. doi: 10.3390/sports6030066.

12.

Noncovalent inhibition of C481S Bruton tyrosine kinase by GDC-0853: a new treatment strategy for ibrutinib-resistant CLL.

Reiff SD, Muhowski EM, Guinn D, Lehman A, Fabian CA, Cheney C, Mantel R, Smith L, Johnson AJ, Young WB, Johnson AR, Liu L, Byrd JC, Woyach JA.

Blood. 2018 Sep 6;132(10):1039-1049. doi: 10.1182/blood-2017-10-809020. Epub 2018 Jul 17.

PMID:
30018078
13.

Association Between Pre-season Training and Performance in Elite Australian Football.

McCaskie CJ, Young WB, Fahrner BB, Sim M.

Int J Sports Physiol Perform. 2018 Jun 12:1-25. doi: 10.1123/ijspp.2018-0086. [Epub ahead of print]

PMID:
29893608
14.

Relationship Between Selected Physical Qualities, Bowling Kinematics, and Pace Bowling Skill in Club-Standard Cricketers.

Feros SA, Young WB, OʼBrien BJ.

J Strength Cond Res. 2018 Apr 26. doi: 10.1519/JSC.0000000000002587. [Epub ahead of print]

PMID:
29702520
15.

Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development.

Crawford JJ, Johnson AR, Misner DL, Belmont LD, Castanedo G, Choy R, Coraggio M, Dong L, Eigenbrot C, Erickson R, Ghilardi N, Hau J, Katewa A, Kohli PB, Lee W, Lubach JW, McKenzie BS, Ortwine DF, Schutt L, Tay S, Wei B, Reif K, Liu L, Wong H, Young WB.

J Med Chem. 2018 Mar 22;61(6):2227-2245. doi: 10.1021/acs.jmedchem.7b01712. Epub 2018 Feb 23.

PMID:
29457982
16.

De-Stigmatizing Migraine - With Words.

Young WB.

Headache. 2018 Feb;58(2):319-321. doi: 10.1111/head.13209. Epub 2017 Nov 15. No abstract available.

PMID:
29139106
17.

Quantifying Cricket Fast-Bowling Skill.

Feros SA, Young WB, O'Brien BJ.

Int J Sports Physiol Perform. 2018 Aug 1;13(7):830-838. doi: 10.1123/ijspp.2017-0169. Epub 2018 Jul 27. Review.

PMID:
28952840
18.

Medicinal Chemistry: Where Are All the Women?

Huryn DM, Bolognesi ML, Young WB.

ACS Med Chem Lett. 2017 Aug 25;8(9):900-902. doi: 10.1021/acsmedchemlett.7b00321. eCollection 2017 Sep 14.

19.

Discovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties.

Wang X, Barbosa J, Blomgren P, Bremer MC, Chen J, Crawford JJ, Deng W, Dong L, Eigenbrot C, Gallion S, Hau J, Hu H, Johnson AR, Katewa A, Kropf JE, Lee SH, Liu L, Lubach JW, Macaluso J, Maciejewski P, Mitchell SA, Ortwine DF, DiPaolo J, Reif K, Scheerens H, Schmitt A, Wong H, Xiong JM, Xu J, Zhao Z, Zhou F, Currie KS, Young WB.

ACS Med Chem Lett. 2017 May 3;8(6):608-613. doi: 10.1021/acsmedchemlett.7b00103. eCollection 2017 Jun 8.

20.

The Reliability and Sensitivity of Performance Measures in a Novel Pace-Bowling Test.

Feros SA, Young WB, O'Brien BJ.

Int J Sports Physiol Perform. 2018 Feb 1;13(2):151-155. doi: 10.1123/ijspp.2017-0140. Epub 2018 Feb 12.

PMID:
28530507
21.

CRISPR Editing Technology in Biological and Biomedical Investigation.

White MK, Kaminski R, Young WB, Roehm PC, Khalili K.

J Cell Biochem. 2017 Nov;118(11):3586-3594. doi: 10.1002/jcb.26099. Epub 2017 Jul 4. Review.

22.

Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.

Katewa A, Wang Y, Hackney JA, Huang T, Suto E, Ramamoorthi N, Austin CD, Bremer M, Chen JZ, Crawford JJ, Currie KS, Blomgren P, DeVoss J, DiPaolo JA, Hau J, Johnson A, Lesch J, DeForge LE, Lin Z, Liimatta M, Lubach JW, McVay S, Modrusan Z, Nguyen A, Poon C, Wang J, Liu L, Lee WP, Wong H, Young WB, Townsend MJ, Reif K.

JCI Insight. 2017 Apr 6;2(7):e90111. doi: 10.1172/jci.insight.90111.

23.

In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models.

Yin C, Zhang T, Qu X, Zhang Y, Putatunda R, Xiao X, Li F, Xiao W, Zhao H, Dai S, Qin X, Mo X, Young WB, Khalili K, Hu W.

Mol Ther. 2017 May 3;25(5):1168-1186. doi: 10.1016/j.ymthe.2017.03.012. Epub 2017 Mar 30.

24.

Specific and Stable Suppression of HIV Provirus Expression In Vitro by Chimeric Zinc Finger DNA Methyltransferase 1.

Deng J, Qu X, Lu P, Yang X, Zhu Y, Ji H, Wang Y, Jiang Z, Li X, Zhong Y, Yang H, Pan H, Young WB, Zhu H.

Mol Ther Nucleic Acids. 2017 Mar 17;6:233-242. doi: 10.1016/j.omtn.2017.01.002. Epub 2017 Jan 24.

25.

Reliability of a Field Test of Defending and Attacking Agility in Australian Football and Relationships to Reactive Strength.

Young WB, Murray MP.

J Strength Cond Res. 2017 Feb;31(2):509-516. doi: 10.1519/JSC.0000000000001498.

PMID:
28129280
26.

Bruton's Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats.

Erickson RI, Schutt LK, Tarrant JM, McDowell M, Liu L, Johnson AR, Lewin-Koh SC, Hedehus M, Ross J, Carano RA, Staflin K, Zhong F, Crawford JJ, Zhong S, Reif K, Katewa A, Wong H, Young WB, Dambach DM, Misner DL.

J Pharmacol Exp Ther. 2017 Jan;360(1):226-238. Epub 2016 Nov 7.

PMID:
27821712
27.

Battling Btk Mutants With Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations.

Johnson AR, Kohli PB, Katewa A, Gogol E, Belmont LD, Choy R, Penuel E, Burton L, Eigenbrot C, Yu C, Ortwine DF, Bowman K, Franke Y, Tam C, Estevez A, Mortara K, Wu J, Li H, Lin M, Bergeron P, Crawford JJ, Young WB.

ACS Chem Biol. 2016 Oct 21;11(10):2897-2907. Epub 2016 Sep 7.

PMID:
27571029
28.

Negative Feedback Regulation of HIV-1 by Gene Editing Strategy.

Kaminski R, Chen Y, Salkind J, Bella R, Young WB, Ferrante P, Karn J, Malcolm T, Hu W, Khalili K.

Sci Rep. 2016 Aug 16;6:31527. doi: 10.1038/srep31527.

29.

The Effects of Plyometric Training on Change-of-Direction Ability: A Meta-Analysis.

Asadi A, Arazi H, Young WB, Sáez de Villarreal E.

Int J Sports Physiol Perform. 2016 Jul;11(5):563-73. doi: 10.1123/ijspp.2015-0694. Epub 2016 May 3. Review.

PMID:
27139591
30.

Functional screening of guide RNAs targeting the regulatory and structural HIV-1 viral genome for a cure of AIDS.

Yin C, Zhang T, Li F, Yang F, Putatunda R, Young WB, Khalili K, Hu W, Zhang Y.

AIDS. 2016 May 15;30(8):1163-74. doi: 10.1097/QAD.0000000000001079.

31.

Long-Term Pain Reduction Does Not Imply Improved Functional Outcome in Patients Treated With Combined Supraorbital and Occipital Nerve Stimulation for Chronic Migraine.

Clark SW, Wu C, Boorman DW, Chalouhi N, Zanaty M, Oshinsky M, Young WB, Silberstein SD, Sharan AD.

Neuromodulation. 2016 Jul;19(5):507-14. doi: 10.1111/ner.12400. Epub 2016 Feb 10.

PMID:
26861893
32.

Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability.

Young WB, Barbosa J, Blomgren P, Bremer MC, Crawford JJ, Dambach D, Eigenbrot C, Gallion S, Johnson AR, Kropf JE, Lee SH, Liu L, Lubach JW, Macaluso J, Maciejewski P, Mitchell SA, Ortwine DF, Di Paolo J, Reif K, Scheerens H, Schmitt A, Wang X, Wong H, Xiong JM, Xu J, Yu C, Zhao Z, Currie KS.

Bioorg Med Chem Lett. 2016 Jan 15;26(2):575-579. doi: 10.1016/j.bmcl.2015.11.076. Epub 2015 Nov 24.

PMID:
26675441
33.

CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs.

Zhang Y, Yin C, Zhang T, Li F, Yang W, Kaminski R, Fagan PR, Putatunda R, Young WB, Khalili K, Hu W.

Sci Rep. 2015 Nov 5;5:16277. doi: 10.1038/srep16277.

34.

Visualization and quantification of simian immunodeficiency virus-infected cells using non-invasive molecular imaging.

Song J, Cai Z, White AG, Jin T, Wang X, Kadayakkara D, Anderson CJ, Ambrose Z, Young WB.

J Gen Virol. 2015 Oct;96(10):3131-42. doi: 10.1099/jgv.0.000245. Epub 2015 Jul 14.

35.

The Effects of Frontal- and Sagittal-Plane Plyometrics on Change-of-Direction Speed and Power in Adolescent Female Basketball Players.

McCormick BT, Hannon JC, Newton M, Shultz B, Detling N, Young WB.

Int J Sports Physiol Perform. 2016 Jan;11(1):102-7. doi: 10.1123/ijspp.2015-0058. Epub 2015 May 26.

PMID:
26023808
36.

Potent and selective Bruton's tyrosine kinase inhibitors: discovery of GDC-0834.

Young WB, Barbosa J, Blomgren P, Bremer MC, Crawford JJ, Dambach D, Gallion S, Hymowitz SG, Kropf JE, Lee SH, Liu L, Lubach JW, Macaluso J, Maciejewski P, Maurer B, Mitchell SA, Ortwine DF, Di Paolo J, Reif K, Scheerens H, Schmitt A, Sowell CG, Wang X, Wong H, Xiong JM, Xu J, Zhao Z, Currie KS.

Bioorg Med Chem Lett. 2015 Mar 15;25(6):1333-7. doi: 10.1016/j.bmcl.2015.01.032. Epub 2015 Feb 7.

PMID:
25701252
37.

Efficacy and Tolerability of STOPAIN for a Migraine Attack.

St Cyr A, Chen A, Bradley KC, Yuan H, Silberstein SD, Young WB.

Front Neurol. 2015 Feb 4;6:11. doi: 10.3389/fneur.2015.00011. eCollection 2015.

38.

Different methods of training load quantification and their relationship to injury and illness in elite Australian football.

Veugelers KR, Young WB, Fahrner B, Harvey JT.

J Sci Med Sport. 2016 Jan;19(1):24-8. doi: 10.1016/j.jsams.2015.01.001. Epub 2015 Jan 23.

PMID:
25669126
39.

Physical qualities predict change-of-direction speed but not defensive agility in Australian rules football.

Young WB, Miller IR, Talpey SW.

J Strength Cond Res. 2015 Jan;29(1):206-12. doi: 10.1519/JSC.0000000000000614.

PMID:
25028996
40.

When 'just doing it' is not enough: assessing the fidelity of player performance of an injury prevention exercise program.

Fortington LV, Donaldson A, Lathlean T, Young WB, Gabbe BJ, Lloyd D, Finch CF.

J Sci Med Sport. 2015 May;18(3):272-7. doi: 10.1016/j.jsams.2014.05.001. Epub 2014 May 16.

PMID:
24930985
41.

Effect of Instructions on Selected Jump Squat Variables.

Talpey SW, Young WB, Beseler B.

J Strength Cond Res. 2016 Sep;30(9):2508-13. doi: 10.1519/JSC.0000000000000435.

PMID:
24552800
42.

Occipital nerve stimulation for chronic migraine.

Young WB.

Curr Pain Headache Rep. 2014 Feb;18(2):396. doi: 10.1007/s11916-013-0396-x.

PMID:
24474153
43.

Duloxetine prophylaxis for episodic migraine in persons without depression: a prospective study.

Young WB, Bradley KC, Anjum MW, Gebeline-Myers C.

Headache. 2013 Oct;53(9):1430-7. doi: 10.1111/head.12205. Epub 2013 Aug 28.

PMID:
24032526
44.

Relationships Between Reactive Agility Movement Time and Unilateral Vertical, Horizontal, and Lateral Jumps.

Henry GJ, Dawson B, Lay BS, Young WB.

J Strength Cond Res. 2016 Sep;30(9):2514-21. doi: 10.1519/JSC.0b013e3182a20ebc.

PMID:
23820562
45.

Accelerometer load as a measure of activity profile in different standards of netball match play.

Cormack SJ, Smith RL, Mooney MM, Young WB, O'Brien BJ.

Int J Sports Physiol Perform. 2014 Mar;9(2):283-91. doi: 10.1123/ijspp.2012-0216. Epub 2013 Jun 24.

PMID:
23799824
46.

The acute effects of conventional, complex, and contrast protocols on lower-body power.

Talpey SW, Young WB, Saunders N.

J Strength Cond Res. 2014 Feb;28(2):361-6. doi: 10.1519/JSC.0b013e318299a68b.

PMID:
23689340
47.

Decision-making accuracy in reactive agility: quantifying the cost of poor decisions.

Henry GJ, Dawson B, Lay BS, Young WB.

J Strength Cond Res. 2013 Nov;27(11):3190-6. doi: 10.1519/JSC.0b013e31828b8da4.

PMID:
23439348
48.

Expert consensus recommendations for the performance of peripheral nerve blocks for headaches--a narrative review.

Blumenfeld A, Ashkenazi A, Napchan U, Bender SD, Klein BC, Berliner R, Ailani J, Schim J, Friedman DI, Charleston L 4th, Young WB, Robertson CE, Dodick DW, Silberstein SD, Robbins MS.

Headache. 2013 Mar;53(3):437-46. doi: 10.1111/head.12053. Epub 2013 Feb 13. Review.

PMID:
23406160
49.

The stigma of migraine.

Young WB, Park JE, Tian IX, Kempner J.

PLoS One. 2013;8(1):e54074. doi: 10.1371/journal.pone.0054074. Epub 2013 Jan 16.

50.

U6 promoter-enhanced GlnUAG suppressor tRNA has higher suppression efficacy and can be stably expressed in 293 cells.

Koukuntla R, Ramsey WJ, Young WB, Link CJ.

J Gene Med. 2013 Feb;15(2):93-101. doi: 10.1002/jgm.2696.

PMID:
23303531

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