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Items: 1 to 50 of 186

1.

Fecal Microbiota Transplantations: Where Are We, Where Are We Going, and What Is the Role of the Clinical Laboratory?

Ransom EM, Burnham CD, Jones L, Kraft CS, McDonald LC, Reinink AR, Young VB.

Clin Chem. 2020 Apr 1;66(4):512-517. doi: 10.1093/clinchem/hvaa021. No abstract available.

PMID:
32232453
2.

The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View.

Xavier JB, Young VB, Skufca J, Ginty F, Testerman T, Pearson AT, Macklin P, Mitchell A, Shmulevich I, Xie L, Caporaso JG, Crandall KA, Simone NL, Godoy-Vitorino F, Griffin TJ, Whiteson KL, Gustafson HH, Slade DJ, Schmidt TM, Walther-Antonio MRS, Korem T, Webb-Robertson BM, Styczynski MP, Johnson WE, Jobin C, Ridlon JM, Koh AY, Yu M, Kelly L, Wargo JA.

Trends Cancer. 2020 Mar;6(3):192-204. doi: 10.1016/j.trecan.2020.01.004. Epub 2020 Feb 7. Review.

3.

Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota.

Nagao-Kitamoto H, Leslie JL, Kitamoto S, Jin C, Thomsson KA, Gillilland MG 3rd, Kuffa P, Goto Y, Jenq RR, Ishii C, Hirayama A, Seekatz AM, Martens EC, Eaton KA, Kao JY, Fukuda S, Higgins PDR, Karlsson NG, Young VB, Kamada N.

Nat Med. 2020 Feb 17. doi: 10.1038/s41591-020-0764-0. [Epub ahead of print]

PMID:
32066975
4.

Genetic Determinants of Trehalose Utilization Are Not Associated With Severe Clostridium difficile Infection Outcome.

Saund K, Rao K, Young VB, Snitkin ES.

Open Forum Infect Dis. 2020 Jan 4;7(1):ofz548. doi: 10.1093/ofid/ofz548. eCollection 2020 Jan.

5.

Temporal Gut Microbial Changes Predict Recurrent Clostridiodes Difficile Infection in Patients With and Without Ulcerative Colitis.

Lee AA, Rao K, Limsrivilai J, Gillilland M, Malamet B, Briggs E, Young VB, Higgins PDR.

Inflamm Bowel Dis. 2020 Jan 23. pii: izz335. doi: 10.1093/ibd/izz335. [Epub ahead of print]

PMID:
31971239
6.

Dietary Xanthan Gum Alters Antibiotic Efficacy against the Murine Gut Microbiota and Attenuates Clostridioides difficile Colonization.

Schnizlein MK, Vendrov KC, Edwards SJ, Martens EC, Young VB.

mSphere. 2020 Jan 8;5(1). pii: e00708-19. doi: 10.1128/mSphere.00708-19.

7.

Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis.

Das NK, Schwartz AJ, Barthel G, Inohara N, Liu Q, Sankar A, Hill DR, Ma X, Lamberg O, Schnizlein MK, Arqués JL, Spence JR, Nunez G, Patterson AD, Sun D, Young VB, Shah YM.

Cell Metab. 2020 Jan 7;31(1):115-130.e6. doi: 10.1016/j.cmet.2019.10.005. Epub 2019 Nov 7.

PMID:
31708445
8.

Corrigendum: The Role of Fecal Microbiota Transplantation in Reducing Intestinal Colonization With Antibiotic-Resistant Organisms: The Current Landscape and Future Directions.

Woodworth MH, Hayden MK, Young VB, Kwon JH.

Open Forum Infect Dis. 2019 Oct 20;6(10):ofz391. doi: 10.1093/ofid/ofz391. eCollection 2019 Oct.

9.

Bacteria Detected in both Urine and Open Wounds in Nursing Home Residents: a Pilot Study.

Libertucci J, Bassis CM, Cassone M, Gibson K, Lansing B, Mody L, Young VB, Meddings J.

mSphere. 2019 Aug 28;4(4). pii: e00463-19. doi: 10.1128/mSphere.00463-19.

10.
11.

Gut Microbiota and Colonization Resistance against Bacterial Enteric Infection.

Ducarmon QR, Zwittink RD, Hornung BVH, van Schaik W, Young VB, Kuijper EJ.

Microbiol Mol Biol Rev. 2019 Jun 5;83(3). pii: e00007-19. doi: 10.1128/MMBR.00007-19. Print 2019 Aug 21. Review.

PMID:
31167904
12.

Using Machine Learning and the Electronic Health Record to Predict Complicated Clostridium difficile Infection.

Li BY, Oh J, Young VB, Rao K, Wiens J.

Open Forum Infect Dis. 2019 Apr 20;6(5):ofz186. doi: 10.1093/ofid/ofz186. eCollection 2019 May.

13.

Intestinal Damage Fades, but Insults Linger: Setting the Immunological Tone for Infection.

Abernathy-Close L, Young VB.

Cell Host Microbe. 2019 May 8;25(5):636-637. doi: 10.1016/j.chom.2019.04.008.

PMID:
31071292
14.

Increases in Colonic Bacterial Diversity after ω-3 Fatty Acid Supplementation Predict Decreased Colonic Prostaglandin E2 Concentrations in Healthy Adults.

Djuric Z, Bassis CM, Plegue MA, Sen A, Turgeon DK, Herman K, Young VB, Brenner DE, Ruffin MT.

J Nutr. 2019 Jul 1;149(7):1170-1179. doi: 10.1093/jn/nxy255.

PMID:
31051496
15.

Outbreak of Murine Infection with Clostridium difficile Associated with the Administration of a Pre- and Perinatal Methyl Donor Diet.

Mau T, Eckley SS, Bergin IL, Saund K, Villano JS, Vendrov KC, Snitkin ES, Young VB, Yung R.

mSphere. 2019 Mar 20;4(2). pii: e00138-19. doi: 10.1128/mSphereDirect.00138-19.

16.

Spatial and Temporal Analysis of the Stomach and Small-Intestinal Microbiota in Fasted Healthy Humans.

Seekatz AM, Schnizlein MK, Koenigsknecht MJ, Baker JR, Hasler WL, Bleske BE, Young VB, Sun D.

mSphere. 2019 Mar 13;4(2). pii: e00126-19. doi: 10.1128/mSphere.00126-19.

17.

The Gut Microbiota Is Associated with Clearance of Clostridium difficile Infection Independent of Adaptive Immunity.

Leslie JL, Vendrov KC, Jenior ML, Young VB.

mSphere. 2019 Jan 30;4(1). pii: e00698-18. doi: 10.1128/mSphereDirect.00698-18.

18.

The role of the microbiota in infectious diseases.

Libertucci J, Young VB.

Nat Microbiol. 2019 Jan;4(1):35-45. doi: 10.1038/s41564-018-0278-4. Epub 2018 Dec 13. Review.

PMID:
30546094
19.

Increased Relative Abundance of Klebsiella pneumoniae Carbapenemase-producing Klebsiella pneumoniae Within the Gut Microbiota Is Associated With Risk of Bloodstream Infection in Long-term Acute Care Hospital Patients.

Shimasaki T, Seekatz A, Bassis C, Rhee Y, Yelin RD, Fogg L, Dangana T, Cisneros EC, Weinstein RA, Okamoto K, Lolans K, Schoeny M, Lin MY, Moore NM, Young VB, Hayden MK; Centers for Disease Control and Prevention Epicenters Program.

Clin Infect Dis. 2019 May 30;68(12):2053-2059. doi: 10.1093/cid/ciy796.

20.

Novel therapies and preventative strategies for primary and recurrent Clostridium difficile infections.

Dieterle MG, Rao K, Young VB.

Ann N Y Acad Sci. 2019 Jan;1435(1):110-138. doi: 10.1111/nyas.13958. Epub 2018 Sep 21. Review.

21.

The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis.

Truax AD, Chen L, Tam JW, Cheng N, Guo H, Koblansky AA, Chou WC, Wilson JE, Brickey WJ, Petrucelli A, Liu R, Cooper DE, Koenigsknecht MJ, Young VB, Netea MG, Stienstra R, Sartor RB, Montgomery SA, Coleman RA, Ting JP.

Cell Host Microbe. 2018 Sep 12;24(3):364-378.e6. doi: 10.1016/j.chom.2018.08.009.

22.

Active Shooter Training in the Emergency Department: A Safety Initiative.

Sanchez L, Young VB, Baker M.

J Emerg Nurs. 2018 Nov;44(6):598-604. doi: 10.1016/j.jen.2018.07.002. Epub 2018 Aug 27.

PMID:
30166117
23.

Gut Microbiota and Clinical Features Distinguish Colonization With Klebsiella pneumoniae Carbapenemase-Producing Klebsiella pneumoniae at the Time of Admission to a Long-term Acute Care Hospital.

Seekatz AM, Bassis CM, Fogg L, Moore NM, Rhee Y, Lolans K, Weinstein RA, Lin MY, Young VB, Hayden MK; Centers for Disease Control and Prevention Epicenters Program.

Open Forum Infect Dis. 2018 Jul 31;5(8):ofy190. doi: 10.1093/ofid/ofy190. eCollection 2018 Aug.

24.

Clostridium difficile Alters the Structure and Metabolism of Distinct Cecal Microbiomes during Initial Infection To Promote Sustained Colonization.

Jenior ML, Leslie JL, Young VB, Schloss PD.

mSphere. 2018 Jun 27;3(3). pii: e00261-18. doi: 10.1128/mSphere.00261-18. Print 2018 Jun 27.

25.

Presence of multiple Clostridium difficile strains at primary infection is associated with development of recurrent disease.

Seekatz AM, Wolfrum E, DeWald CM, Putler RKB, Vendrov KC, Rao K, Young VB.

Anaerobe. 2018 Oct;53:74-81. doi: 10.1016/j.anaerobe.2018.05.017. Epub 2018 May 31.

26.

An Observational Cohort Study of Clostridium difficile Ribotype 027 and Recurrent Infection.

Rao K, Higgins PDR, Young VB.

mSphere. 2018 May 23;3(3). pii: e00033-18. doi: 10.1128/mSphere.00033-18. eCollection 2018 May-Jun.

27.

Restoration of short chain fatty acid and bile acid metabolism following fecal microbiota transplantation in patients with recurrent Clostridium difficile infection.

Seekatz AM, Theriot CM, Rao K, Chang YM, Freeman AE, Kao JY, Young VB.

Anaerobe. 2018 Oct;53:64-73. doi: 10.1016/j.anaerobe.2018.04.001. Epub 2018 Apr 12.

28.

Clostridium difficile Infection and the Tangled Web of Interactions Among Host, Pathogen, and Microbiota.

Seekatz AM, Young VB.

Gastroenterology. 2018 May;154(6):1573-1576. doi: 10.1053/j.gastro.2018.03.036. Epub 2018 Mar 28. No abstract available.

PMID:
29601830
29.

A Generalizable, Data-Driven Approach to Predict Daily Risk of Clostridium difficile Infection at Two Large Academic Health Centers.

Oh J, Makar M, Fusco C, McCaffrey R, Rao K, Ryan EE, Washer L, West LR, Young VB, Guttag J, Hooper DC, Shenoy ES, Wiens J.

Infect Control Hosp Epidemiol. 2018 Apr;39(4):425-433. doi: 10.1017/ice.2018.16.

30.

Real-time Measurement of Epithelial Barrier Permeability in Human Intestinal Organoids.

Hill DR, Huang S, Tsai YH, Spence JR, Young VB.

J Vis Exp. 2017 Dec 18;(130). doi: 10.3791/56960.

31.

Impact of the Levonorgestrel-Releasing Intrauterine System on the Progression of Chlamydia trachomatis Infection to Pelvic Inflammatory Disease in a Baboon Model.

Eastman AJ, Bergin IL, Chai D, Bassis CM, LeBar W, Oluoch GO, Liechty ER, Nyachieo A, Young VB, Aronoff DM, Patton DL, Bell JD.

J Infect Dis. 2018 Jan 30;217(4):656-666. doi: 10.1093/infdis/jix545.

32.

High-resolution profiling of the gut microbiome reveals the extent of Clostridium difficile burden.

Daquigan N, Seekatz AM, Greathouse KL, Young VB, White JR.

NPJ Biofilms Microbiomes. 2017 Dec 5;3:35. doi: 10.1038/s41522-017-0043-0. eCollection 2017.

33.

Probiotics for prevention of Clostridium difficile infection.

Mills JP, Rao K, Young VB.

Curr Opin Gastroenterol. 2018 Jan;34(1):3-10. doi: 10.1097/MOG.0000000000000410. Review.

34.

Capsules for Fecal Microbiota Transplantation in Recurrent Clostridium difficile Infection: The New Way Forward or a Tough Pill to Swallow?

Rao K, Young VB, Malani PN.

JAMA. 2017 Nov 28;318(20):1979-1980. doi: 10.1001/jama.2017.17969. No abstract available.

35.

Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium.

Hill DR, Huang S, Nagy MS, Yadagiri VK, Fields C, Mukherjee D, Bons B, Dedhia PH, Chin AM, Tsai YH, Thodla S, Schmidt TM, Walk S, Young VB, Spence JR.

Elife. 2017 Nov 7;6. pii: e29132. doi: 10.7554/eLife.29132.

36.

Corrigendum: NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth.

Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP.

Nat Immunol. 2017 Oct 18;18(11):1270. doi: 10.1038/ni1117-1270b.

PMID:
29044233
37.

Clostridium difficile Colonizes Alternative Nutrient Niches during Infection across Distinct Murine Gut Microbiomes.

Jenior ML, Leslie JL, Young VB, Schloss PD.

mSystems. 2017 Jul 25;2(4). pii: e00063-17. doi: 10.1128/mSystems.00063-17. eCollection 2017 Jul-Aug.

38.

Erratum: NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth.

Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP.

Nat Immunol. 2017 Jul 19;18(8):951. doi: 10.1038/ni0817-951e. No abstract available.

PMID:
28722719
39.

Is Clostridium difficile infection a risk factor for subsequent bloodstream infection?

Ulrich RJ, Santhosh K, Mogle JA, Young VB, Rao K.

Anaerobe. 2017 Dec;48:27-33. doi: 10.1016/j.anaerobe.2017.06.020. Epub 2017 Jun 29.

40.

Effects of intrauterine contraception on the vaginal microbiota.

Bassis CM, Allsworth JE, Wahl HN, Sack DE, Young VB, Bell JD.

Contraception. 2017 Sep;96(3):189-195. doi: 10.1016/j.contraception.2017.05.017. Epub 2017 Jun 15.

41.

Treatment With Fecal Microbiota Transplantation: The Need for Complete Methodological Reporting for Clinical Trials.

Young VB.

Ann Intern Med. 2017 Jul 4;167(1):61-62. doi: 10.7326/M17-1157. Epub 2017 May 23. No abstract available.

42.

Probiotics for Prevention of Clostridium difficile Infection in Hospitalized Patients: Is the Jury Still Out?

Rao K, Young VB.

Gastroenterology. 2017 Jun;152(8):1817-1819. doi: 10.1053/j.gastro.2017.04.027. Epub 2017 Apr 28. No abstract available.

43.

Effective Management of Pain and Anxiety for the Pediatric Patient in the Emergency Department.

Young VB.

Crit Care Nurs Clin North Am. 2017 Jun;29(2):205-216. doi: 10.1016/j.cnc.2017.01.007. Epub 2017 Mar 18. Review.

PMID:
28460701
44.

Reducing Recurrence of C. difficile Infection.

Dieterle MG, Young VB.

Cell. 2017 Apr 20;169(3):375. doi: 10.1016/j.cell.2017.03.039.

45.

Old and new models for studying host-microbe interactions in health and disease: C. difficile as an example.

Young VB.

Am J Physiol Gastrointest Liver Physiol. 2017 Jun 1;312(6):G623-G627. doi: 10.1152/ajpgi.00341.2016. Epub 2017 Mar 30. Review.

46.

Comparison of stool versus rectal swab samples and storage conditions on bacterial community profiles.

Bassis CM, Moore NM, Lolans K, Seekatz AM, Weinstein RA, Young VB, Hayden MK; CDC Prevention Epicenters Program.

BMC Microbiol. 2017 Mar 31;17(1):78. doi: 10.1186/s12866-017-0983-9.

47.

The role of the microbiome in human health and disease: an introduction for clinicians.

Young VB.

BMJ. 2017 Mar 15;356:j831. doi: 10.1136/bmj.j831. Review.

PMID:
28298355
48.

NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth.

Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP.

Nat Immunol. 2017 May;18(5):541-551. doi: 10.1038/ni.3690. Epub 2017 Mar 13. Erratum in: Nat Immunol. 2017 Jul 19;18(8):951. Erratum in: Nat Immunol. 2017 Oct 18;18(11):1270.

49.

Ensuring Safe Transfer of Pediatric Patients: A Quality Improvement Project to Standardize Handoff Communication.

Patton LJ, Tidwell JD, Falder-Saeed KL, Young VB, Lewis BD, Binder JF.

J Pediatr Nurs. 2017 May - Jun;34:44-52. doi: 10.1016/j.pedn.2017.01.004. Epub 2017 Jan 26. Review.

PMID:
28131547
50.

The anti-inflammatory drug mesalamine targets bacterial polyphosphate accumulation.

Dahl JU, Gray MJ, Bazopoulou D, Beaufay F, Lempart J, Koenigsknecht MJ, Wang Y, Baker JR, Hasler WL, Young VB, Sun D, Jakob U.

Nat Microbiol. 2017 Jan 23;2:16267. doi: 10.1038/nmicrobiol.2016.267.

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