Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 623

1.

Data for engineering lipid metabolism of Chinese hamster ovary (CHO) cells for enhanced recombinant protein production.

Budge JD, Knight TJ, Povey J, Roobol J, Brown IR, Singh G, Dean A, Turner S, Jaques CM, Young RJ, Racher AJ, Smales CM.

Data Brief. 2020 Jan 31;29:105217. doi: 10.1016/j.dib.2020.105217. eCollection 2020 Apr.

2.

Prognostic and radiographic correlates of a prospectively collected molecularly profiled cohort of IDH1/2-wildtype astrocytomas.

Lin AL, Rosenblum M, Mellinghoff IK, Tabar VS, Ogilvie S, Schaff L, Yang TJ, Young RJ, Taylor BS, Jonsson P, Bale TA.

Brain Pathol. 2020 Jan 26. doi: 10.1111/bpa.12826. [Epub ahead of print]

PMID:
31984581
3.

Realising biaxial reinforcement via orientation-induced anisotropic swelling in graphene-based elastomers.

Liu M, Kinloch IA, Young RJ, Papageorgiou DG.

Nanoscale. 2020 Feb 7;12(5):3377-3386. doi: 10.1039/c9nr09988c. Epub 2020 Jan 27.

PMID:
31984405
4.

Edible unclonable functions.

Leem JW, Kim MS, Choi SH, Kim SR, Kim SW, Song YM, Young RJ, Kim YL.

Nat Commun. 2020 Jan 16;11(1):328. doi: 10.1038/s41467-019-14066-5.

5.

Mechanisms of mechanical reinforcement by graphene and carbon nanotubes in polymer nanocomposites.

Papageorgiou DG, Li Z, Liu M, Kinloch IA, Young RJ.

Nanoscale. 2020 Jan 28;12(4):2228-2267. doi: 10.1039/c9nr06952f. Epub 2020 Jan 13.

PMID:
31930259
6.

Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase Inhibitors: Expeditious Reconstruction of Suboptimal Hits into a Series with Potent in Vivo Activity.

Borthwick JA, Alemparte C, Wall I, Whitehurst BC, Argyrou A, Burley G, de Dios-Anton P, Guijarro L, Monteiro MC, Ortega F, Suckling CJ, Pichel JC, Cacho M, Young RJ.

J Med Chem. 2020 Jan 22. doi: 10.1021/acs.jmedchem.9b01561. [Epub ahead of print]

PMID:
31922409
7.

Captive-born collared peccaries learning about their predators: Lessons learnt but not remembered.

de Faria CM, de Souza Sá F, Lovenstain Costa DD, da Silva MM, da Silva BC, Young RJ, de Azevedo CS.

Behav Processes. 2020 Feb;171:104031. doi: 10.1016/j.beproc.2019.104031. Epub 2019 Dec 31.

PMID:
31899275
8.

DCE-MRI perfusion predicts pseudoprogression in metastatic melanoma treated with immunotherapy.

Umemura Y, Wang D, Peck KK, Flynn J, Zhang Z, Fatovic R, Anderson ES, Beal K, Shoushtari AN, Kaley T, Young RJ.

J Neurooncol. 2020 Jan;146(2):339-346. doi: 10.1007/s11060-019-03379-6. Epub 2019 Dec 24.

PMID:
31873875
9.

18F-Fluorocholine PET uptake correlates with pathologic evidence of recurrent tumor after stereotactic radiosurgery for brain metastases.

Grkovski M, Kohutek ZA, Schöder H, Brennan CW, Tabar VS, Gutin PH, Zhang Z, Young RJ, Beattie BJ, Zanzonico PB, Huse JT, Rosenblum MK, Blasberg RG, Humm JL, Beal K.

Eur J Nucl Med Mol Imaging. 2019 Dec 21. doi: 10.1007/s00259-019-04628-6. [Epub ahead of print]

PMID:
31865407
10.

Gaps in terrestrial soundscape research: It's time to focus on tropical wildlife.

Scarpelli MDA, Ribeiro MC, Teixeira FZ, Young RJ, Teixeira CP.

Sci Total Environ. 2020 Mar 10;707:135403. doi: 10.1016/j.scitotenv.2019.135403. Epub 2019 Nov 23. Review.

PMID:
31864000
11.

Validation and characterisation of prognostically significant PD-L1+ immune cells in HPV+ oropharyngeal squamous cell carcinoma.

Young RJ, Bressel M, Porceddu S, Cernelc J, Savas P, Liu H, Urban D, Thai AA, Cooper C, Fua T, Neeson P, Rischin D, Solomon B.

Oral Oncol. 2020 Feb;101:104516. doi: 10.1016/j.oraloncology.2019.104516. Epub 2019 Dec 12.

PMID:
31838340
12.

Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production.

Budge JD, Knight TJ, Povey J, Roobol J, Brown IR, Singh G, Dean A, Turner S, Jaques CM, Young RJ, Racher AJ, Smales CM.

Metab Eng. 2020 Jan;57:203-216. doi: 10.1016/j.ymben.2019.11.007. Epub 2019 Dec 2.

13.

MRI radiomic features are associated with survival in melanoma brain metastases treated with immune checkpoint inhibitors.

Bhatia A, Birger M, Veeraraghavan H, Um H, Tixier F, McKenney AS, Cugliari M, Caviasco A, Bialczak A, Malani R, Flynn J, Zhang Z, Yang TJ, Santomasso BD, Shoushtari AN, Young RJ.

Neuro Oncol. 2019 Dec 17;21(12):1578-1586. doi: 10.1093/neuonc/noz141.

PMID:
31621883
14.

Photodetecting Heterostructures from Graphene and Encapsulated Colloidal Quantum Dot Films.

Black A, Urbanos FJ, Roberts J, Acebrón M, Bernardo-Gavito R, Juárez BH, Robinson BJ, Young RJ, Vázquez de Parga AL, Granados D.

ACS Omega. 2019 Sep 17;4(14):15824-15828. doi: 10.1021/acsomega.9b01449. eCollection 2019 Oct 1.

15.

A Simple Method for Anchoring Silver and Copper Nanoparticles on Single Wall Carbon Nanotubes.

Silva MM, Ribeiro D, Cunha E, Proença MF, Young RJ, Paiva MC.

Nanomaterials (Basel). 2019 Oct 4;9(10). pii: E1416. doi: 10.3390/nano9101416.

16.

MR Perfusion and MR Spectroscopy of Brain Neoplasms.

Gharzeddine K, Hatzoglou V, Holodny AI, Young RJ.

Radiol Clin North Am. 2019 Nov;57(6):1177-1188. doi: 10.1016/j.rcl.2019.07.008. Review.

PMID:
31582043
17.

Comparison of Radiographic Approaches to Assess Treatment Response in Pituitary Adenomas: Is RECIST or RANO Good Enough?

Imber BS, Lin AL, Zhang Z, Keshavamurthy KN, Deipolyi AR, Beal K, Cohen MA, Tabar V, DeAngelis LM, Geer EB, Yang TJ, Young RJ.

J Endocr Soc. 2019 Jul 2;3(9):1693-1706. doi: 10.1210/js.2019-00130. eCollection 2019 Sep 1.

18.

Response to Selective RET Inhibition With LOXO-292 in a Patient With RET Fusion-Positive Lung Cancer With Leptomeningeal Metastases.

Guo R, Schreyer M, Chang JC, Rothenberg SM, Henry D, Cotzia P, Kris MG, Rekhtman N, Young RJ, Hyman DM, Drilon A.

JCO Precis Oncol. 2019;3. doi: 10.1200/PO.19.00021. Epub 2019 Jun 3. No abstract available.

19.

Frequency and outcomes of brain metastases in patients with HER2-mutant lung cancers.

Offin M, Feldman D, Ni A, Myers ML, Lai WV, Pentsova E, Boire A, Daras M, Jordan EJ, Solit DB, Arcila ME, Jones DR, Isbell JM, Beal K, Young RJ, Rudin CM, Riely GJ, Drilon A, Tabar V, DeAngelis LM, Yu HA, Kris MG, Li BT.

Cancer. 2019 Dec 15;125(24):4380-4387. doi: 10.1002/cncr.32461. Epub 2019 Aug 30.

PMID:
31469421
20.

Using Physicochemical Measurements to Influence Better Compound Design.

Bunally SB, Luscombe CN, Young RJ.

SLAS Discov. 2019 Sep;24(8):791-801. doi: 10.1177/2472555219859845.

PMID:
31429385
21.

Identification of an excellent prognosis subset of human papillomavirus-associated oropharyngeal cancer patients by quantification of intratumoral CD103+ immune cell abundance.

Solomon B, Young RJ, Bressel M, Cernelc J, Savas P, Liu H, Urban D, Thai A, Cooper C, Fua T, Neeson P, Loi S, Porceddu SV, Rischin D.

Ann Oncol. 2019 Oct 1;30(10):1638-1646. doi: 10.1093/annonc/mdz271.

PMID:
31400196
22.

Graphene-Based Materials as Strain Sensors in Glass Fiber/Epoxy Model Composites.

Chu J, Marsden AJ, Young RJ, Bissett MA.

ACS Appl Mater Interfaces. 2019 Aug 28;11(34):31338-31345. doi: 10.1021/acsami.9b09862. Epub 2019 Aug 16.

23.

Identification via a Parallel Hit Progression Strategy of Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Plasmodium falciparum Parasite Proliferation.

Sosa Y, Deniskin R, Frame IJ, Steiginga MS, Bandyopadhyay D, Graybill TL, Kallal LA, Ouellette MT, Pope AJ, Widdowson KL, Young RJ, Akabas MH.

ACS Infect Dis. 2019 Oct 11;5(10):1738-1753. doi: 10.1021/acsinfecdis.9b00168. Epub 2019 Aug 14.

PMID:
31373203
24.

Effects of mining truck traffic on cricket calling activity.

Duarte MHL, Caliari EP, Scarpelli MDA, Lobregat GO, Young RJ, Sousa-Lima RS.

J Acoust Soc Am. 2019 Jul;146(1):656. doi: 10.1121/1.5119125.

PMID:
31370619
25.

The strength of mechanically-exfoliated monolayer graphene deformed on a rigid polymer substrate.

Zhao X, Papageorgiou DG, Zhu L, Ding F, Young RJ.

Nanoscale. 2019 Aug 1;11(30):14339-14353. doi: 10.1039/c9nr04720d.

PMID:
31328739
26.

Revisiting the Language of Glycoscience: Readers, Writers and Erasers in Carbohydrate Biochemistry.

Dedola S, Rugen MD, Young RJ, Field RA.

Chembiochem. 2020 Feb 3;21(3):423-427. doi: 10.1002/cbic.201900377. Epub 2019 Nov 4.

PMID:
31317590
27.

Impact of image preprocessing on the scanner dependence of multi-parametric MRI radiomic features and covariate shift in multi-institutional glioblastoma datasets.

Um H, Tixier F, Bermudez D, Deasy JO, Young RJ, Veeraraghavan H.

Phys Med Biol. 2019 Aug 21;64(16):165011. doi: 10.1088/1361-6560/ab2f44.

PMID:
31272093
28.

Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas.

Jonsson P, Lin AL, Young RJ, DiStefano NM, Hyman DM, Li BT, Berger MF, Zehir A, Ladanyi M, Solit DB, Arnold AG, Stadler ZK, Mandelker D, Goldberg ME, Chmielecki J, Pourmaleki M, Ogilvie SQ, Chavan SS, McKeown AT, Manne M, Hyde A, Beal K, Yang TJ, Nolan CP, Pentsova E, Omuro A, Gavrilovic IT, Kaley TJ, Diamond EL, Stone JB, Grommes C, Boire A, Daras M, Piotrowski AF, Miller AM, Gutin PH, Chan TA, Tabar VS, Brennan CW, Rosenblum M, DeAngelis LM, Mellinghoff IK, Taylor BS.

Clin Cancer Res. 2019 Sep 15;25(18):5537-5547. doi: 10.1158/1078-0432.CCR-19-0032. Epub 2019 Jul 1.

PMID:
31263031
29.

Dynamic modulation of the Fermi energy in suspended graphene backgated devices.

Dawood OM, Gupta RK, Monteverde U, Alqahtani FH, Kim HY, Sexton J, Young RJ, Missous M, Migliorato MA.

Sci Technol Adv Mater. 2019 Jun 3;20(1):568-579. doi: 10.1080/14686996.2019.1612710. eCollection 2019.

30.

Negative Gauge Factor Piezoresistive Composites Based on Polymers Filled with MoS2 Nanosheets.

Biccai S, Boland CS, O'Driscoll DP, Harvey A, Gabbett C, O'Suilleabhain DR, Griffin AJ, Li Z, Young RJ, Coleman JN.

ACS Nano. 2019 Jun 25;13(6):6845-6855. doi: 10.1021/acsnano.9b01613. Epub 2019 Jun 14.

PMID:
31199128
31.

Reliability of tumor segmentation in glioblastoma: Impact on the robustness of MRI-radiomic features.

Tixier F, Um H, Young RJ, Veeraraghavan H.

Med Phys. 2019 Aug;46(8):3582-3591. doi: 10.1002/mp.13624. Epub 2019 Jul 5.

PMID:
31131906
32.

Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome.

Walker AL, Bingham RP, Edgar EV, Ferrie A, Holmes DS, Liddle J, Polyakova O, Rella M, Smith KJ, Thorpe JH, Wang Y, White GV, Young RJ, Hovnanian A.

Bioorg Med Chem Lett. 2019 Jun 15;29(12):1454-1458. doi: 10.1016/j.bmcl.2019.04.022. Epub 2019 Apr 12.

PMID:
31005442
33.

Efficacy of MEK inhibition in patients with histiocytic neoplasms.

Diamond EL, Durham BH, Ulaner GA, Drill E, Buthorn J, Ki M, Bitner L, Cho H, Young RJ, Francis JH, Rampal R, Lacouture M, Brody LA, Ozkaya N, Dogan A, Rosen N, Iasonos A, Abdel-Wahab O, Hyman DM.

Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.

34.

Preoperative MRI-radiomics features improve prediction of survival in glioblastoma patients over MGMT methylation status alone.

Tixier F, Um H, Bermudez D, Iyer A, Apte A, Graham MS, Nevel KS, Deasy JO, Young RJ, Veeraraghavan H.

Oncotarget. 2019 Jan 18;10(6):660-672. doi: 10.18632/oncotarget.26578. eCollection 2019 Jan 18.

35.

A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy.

Lelliott EJ, Cullinane C, Martin CA, Walker R, Ramsbottom KM, Souza-Fonseca-Guimaraes F, Abuhammad S, Michie J, Kirby L, Young RJ, Slater A, Lau P, Meeth K, Oliaro J, Haynes N, McArthur GA, Sheppard KE.

Sci Rep. 2019 Feb 4;9(1):1225. doi: 10.1038/s41598-018-37883-y.

36.

Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome.

White GV, Edgar EV, Holmes DS, Lewell XQ, Liddle J, Polyakova O, Smith KJ, Thorpe JH, Walker AL, Wang Y, Young RJ, Hovnanian A.

Bioorg Med Chem Lett. 2019 Mar 15;29(6):821-825. doi: 10.1016/j.bmcl.2019.01.020. Epub 2019 Jan 22.

PMID:
30691925
37.

Identification and Optimization of Novel Small c-Abl Kinase Activators Using Fragment and HTS Methodologies.

Simpson GL, Bertrand SM, Borthwick JA, Campobasso N, Chabanet J, Chen S, Coggins J, Cottom J, Christensen SB, Dawson HC, Evans HL, Hobbs AN, Hong X, Mangatt B, Munoz-Muriedas J, Oliff A, Qin D, Scott-Stevens P, Ward P, Washio Y, Yang J, Young RJ.

J Med Chem. 2019 Feb 28;62(4):2154-2171. doi: 10.1021/acs.jmedchem.8b01872. Epub 2019 Feb 11.

PMID:
30689376
38.

Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid.

Miller AM, Shah RH, Pentsova EI, Pourmaleki M, Briggs S, Distefano N, Zheng Y, Skakodub A, Mehta SA, Campos C, Hsieh WY, Selcuklu SD, Ling L, Meng F, Jing X, Samoila A, Bale TA, Tsui DWY, Grommes C, Viale A, Souweidane MM, Tabar V, Brennan CW, Reiner AS, Rosenblum M, Panageas KS, DeAngelis LM, Young RJ, Berger MF, Mellinghoff IK.

Nature. 2019 Jan;565(7741):654-658. doi: 10.1038/s41586-019-0882-3. Epub 2019 Jan 23.

39.

Expanding the medicinal chemistry synthetic toolbox.

Boström J, Brown DG, Young RJ, Keserü GM.

Nat Rev Drug Discov. 2018 Nov 28;17(12):922. doi: 10.1038/nrd.2018.217.

PMID:
30482954
40.

Quantitative imaging biomarkers alliance (QIBA) recommendations for improved precision of DWI and DCE-MRI derived biomarkers in multicenter oncology trials.

Shukla-Dave A, Obuchowski NA, Chenevert TL, Jambawalikar S, Schwartz LH, Malyarenko D, Huang W, Noworolski SM, Young RJ, Shiroishi MS, Kim H, Coolens C, Laue H, Chung C, Rosen M, Boss M, Jackson EF.

J Magn Reson Imaging. 2019 Jun;49(7):e101-e121. doi: 10.1002/jmri.26518. Epub 2018 Nov 19. Review.

PMID:
30451345
41.

Recessive Host Range Mutants and Unsusceptible Cells That Inactivate Virions without Genome Penetration: Ecological and Technical Implications.

Roznowski AP, Young RJ, Love SD, Andromita AA, Guzman VA, Wilch MH, Block A, McGill A, Lavelle M, Romanova A, Sekiguchi A, Wang M, Burch AD, Fane BA.

J Virol. 2019 Jan 17;93(3). pii: e01767-18. doi: 10.1128/JVI.01767-18. Print 2019 Feb 1.

42.

Composites with carbon nanotubes and graphene: An outlook.

Kinloch IA, Suhr J, Lou J, Young RJ, Ajayan PM.

Science. 2018 Nov 2;362(6414):547-553. doi: 10.1126/science.aat7439. Review.

PMID:
30385571
43.

Comparing the bacterial communities of wild and captive golden mantella frogs: Implications for amphibian conservation.

Passos LF, Garcia G, Young RJ.

PLoS One. 2018 Oct 31;13(10):e0205652. doi: 10.1371/journal.pone.0205652. eCollection 2018.

44.

Minimotifs dysfunction is pervasive in neurodegenerative disorders.

Sharma S, Young RJ, Chen J, Chen X, Oh EC, Schiller MR.

Alzheimers Dement (N Y). 2018 Jul 25;4:414-432. doi: 10.1016/j.trci.2018.06.005. eCollection 2018.

45.

Water Dispersible Few-Layer Graphene Stabilized by a Novel Pyrene Derivative at Micromolar Concentration.

Cunha E, Proença MF, Pereira MG, Fernandes MJ, Young RJ, Strutyński K, Melle-Franco M, Gonzalez-Debs M, Lopes PE, Paiva MDC.

Nanomaterials (Basel). 2018 Aug 30;8(9). pii: E675. doi: 10.3390/nano8090675.

46.

Anomalous twin boundaries in two dimensional materials.

Rooney AP, Li Z, Zhao W, Gholinia A, Kozikov A, Auton G, Ding F, Gorbachev RV, Young RJ, Haigh SJ.

Nat Commun. 2018 Sep 5;9(1):3597. doi: 10.1038/s41467-018-06074-8.

47.

Personality, abnormal behaviour, and health: An evaluation of the welfare of police horses.

Schork IG, de Azevedo CS, Young RJ.

PLoS One. 2018 Sep 5;13(9):e0202750. doi: 10.1371/journal.pone.0202750. eCollection 2018.

48.

Real-world practice level data analysis confirms link between variability within Blood Glucose Monitoring Strip (BGMS) and glycosylated haemoglobin (HbA1c) in Type 1 Diabetes.

Heald AH, Livingston M, Fryer A, Cortes G, Anderson SG, Gadsby R, Laing I, Lunt M, Young RJ, Stedman M.

Int J Clin Pract. 2018 Dec;72(12):e13252. doi: 10.1111/ijcp.13252. Epub 2018 Aug 31.

49.

Expanding the medicinal chemistry synthetic toolbox.

Boström J, Brown DG, Young RJ, Keserü GM.

Nat Rev Drug Discov. 2018 Oct;17(10):709-727. doi: 10.1038/nrd.2018.116. Epub 2018 Aug 24. Review. Erratum in: Nat Rev Drug Discov. 2018 Nov 28;17(12):922.

PMID:
30140018
50.

The Different Physical and Behavioural Characteristics of Zoo Mammals That Influence Their Response to Visitors.

Queiroz MB, Young RJ.

Animals (Basel). 2018 Aug 14;8(8). pii: E139. doi: 10.3390/ani8080139.

Supplemental Content

Loading ...
Support Center