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Items: 1 to 50 of 595

1.

Negative Gauge Factor Piezoresistive Composites Based on Polymers Filled with MoS2 Nanosheets.

Biccai S, Boland CS, O'Driscoll DP, Harvey A, Gabbett C, O'Suilleabhain DR, Griffin AJ, Li Z, Young RJ, Coleman JN.

ACS Nano. 2019 Jun 14. doi: 10.1021/acsnano.9b01613. [Epub ahead of print]

PMID:
31199128
2.

Reliability of tumor segmentation in glioblastoma: impact on the robustness of MRI-radiomic features.

Tixier F, Um H, Young RJ, Veeraraghavan H.

Med Phys. 2019 May 27. doi: 10.1002/mp.13624. [Epub ahead of print]

PMID:
31131906
3.

Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome.

Walker AL, Bingham RP, Edgar EV, Ferrie A, Holmes DS, Liddle J, Polyakova O, Rella M, Smith KJ, Thorpe JH, Wang Y, White GV, Young RJ, Hovnanian A.

Bioorg Med Chem Lett. 2019 Jun 15;29(12):1454-1458. doi: 10.1016/j.bmcl.2019.04.022. Epub 2019 Apr 12.

PMID:
31005442
4.

Efficacy of MEK inhibition in patients with histiocytic neoplasms.

Diamond EL, Durham BH, Ulaner GA, Drill E, Buthorn J, Ki M, Bitner L, Cho H, Young RJ, Francis JH, Rampal R, Lacouture M, Brody LA, Ozkaya N, Dogan A, Rosen N, Iasonos A, Abdel-Wahab O, Hyman DM.

Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.

PMID:
30867592
5.

Preoperative MRI-radiomics features improve prediction of survival in glioblastoma patients over MGMT methylation status alone.

Tixier F, Um H, Bermudez D, Iyer A, Apte A, Graham MS, Nevel KS, Deasy JO, Young RJ, Veeraraghavan H.

Oncotarget. 2019 Jan 18;10(6):660-672. doi: 10.18632/oncotarget.26578. eCollection 2019 Jan 18.

6.

A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy.

Lelliott EJ, Cullinane C, Martin CA, Walker R, Ramsbottom KM, Souza-Fonseca-Guimaraes F, Abuhammad S, Michie J, Kirby L, Young RJ, Slater A, Lau P, Meeth K, Oliaro J, Haynes N, McArthur GA, Sheppard KE.

Sci Rep. 2019 Feb 4;9(1):1225. doi: 10.1038/s41598-018-37883-y.

7.

Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome.

White GV, Edgar EV, Holmes DS, Lewell XQ, Liddle J, Polyakova O, Smith KJ, Thorpe JH, Walker AL, Wang Y, Young RJ, Hovnanian A.

Bioorg Med Chem Lett. 2019 Mar 15;29(6):821-825. doi: 10.1016/j.bmcl.2019.01.020. Epub 2019 Jan 22.

PMID:
30691925
8.

Identification and Optimization of Novel Small c-Abl Kinase Activators Using Fragment and HTS Methodologies.

Simpson GL, Bertrand SM, Borthwick JA, Campobasso N, Chabanet J, Chen S, Coggins J, Cottom J, Christensen SB, Dawson HC, Evans HL, Hobbs AN, Hong X, Mangatt B, Munoz-Muriedas J, Oliff A, Qin D, Scott-Stevens P, Ward P, Washio Y, Yang J, Young RJ.

J Med Chem. 2019 Feb 28;62(4):2154-2171. doi: 10.1021/acs.jmedchem.8b01872. Epub 2019 Feb 11.

PMID:
30689376
9.

Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid.

Miller AM, Shah RH, Pentsova EI, Pourmaleki M, Briggs S, Distefano N, Zheng Y, Skakodub A, Mehta SA, Campos C, Hsieh WY, Selcuklu SD, Ling L, Meng F, Jing X, Samoila A, Bale TA, Tsui DWY, Grommes C, Viale A, Souweidane MM, Tabar V, Brennan CW, Reiner AS, Rosenblum M, Panageas KS, DeAngelis LM, Young RJ, Berger MF, Mellinghoff IK.

Nature. 2019 Jan;565(7741):654-658. doi: 10.1038/s41586-019-0882-3. Epub 2019 Jan 23.

PMID:
30675060
10.

Expanding the medicinal chemistry synthetic toolbox.

Boström J, Brown DG, Young RJ, Keserü GM.

Nat Rev Drug Discov. 2018 Nov 28;17(12):922. doi: 10.1038/nrd.2018.217.

PMID:
30482954
11.

Quantitative imaging biomarkers alliance (QIBA) recommendations for improved precision of DWI and DCE-MRI derived biomarkers in multicenter oncology trials.

Shukla-Dave A, Obuchowski NA, Chenevert TL, Jambawalikar S, Schwartz LH, Malyarenko D, Huang W, Noworolski SM, Young RJ, Shiroishi MS, Kim H, Coolens C, Laue H, Chung C, Rosen M, Boss M, Jackson EF.

J Magn Reson Imaging. 2019 Jun;49(7):e101-e121. doi: 10.1002/jmri.26518. Epub 2018 Nov 19. Review.

PMID:
30451345
12.

Recessive Host Range Mutants and Unsusceptible Cells That Inactivate Virions without Genome Penetration: Ecological and Technical Implications.

Roznowski AP, Young RJ, Love SD, Andromita AA, Guzman VA, Wilch MH, Block A, McGill A, Lavelle M, Romanova A, Sekiguchi A, Wang M, Burch AD, Fane BA.

J Virol. 2019 Jan 17;93(3). pii: e01767-18. doi: 10.1128/JVI.01767-18. Print 2019 Feb 1.

PMID:
30429341
13.

Composites with carbon nanotubes and graphene: An outlook.

Kinloch IA, Suhr J, Lou J, Young RJ, Ajayan PM.

Science. 2018 Nov 2;362(6414):547-553. doi: 10.1126/science.aat7439. Review.

PMID:
30385571
14.

Comparing the bacterial communities of wild and captive golden mantella frogs: Implications for amphibian conservation.

Passos LF, Garcia G, Young RJ.

PLoS One. 2018 Oct 31;13(10):e0205652. doi: 10.1371/journal.pone.0205652. eCollection 2018.

15.

Minimotifs dysfunction is pervasive in neurodegenerative disorders.

Sharma S, Young RJ, Chen J, Chen X, Oh EC, Schiller MR.

Alzheimers Dement (N Y). 2018 Jul 25;4:414-432. doi: 10.1016/j.trci.2018.06.005. eCollection 2018.

16.

Water Dispersible Few-Layer Graphene Stabilized by a Novel Pyrene Derivative at Micromolar Concentration.

Cunha E, Proença MF, Pereira MG, Fernandes MJ, Young RJ, Strutyński K, Melle-Franco M, Gonzalez-Debs M, Lopes PE, Paiva MDC.

Nanomaterials (Basel). 2018 Aug 30;8(9). pii: E675. doi: 10.3390/nano8090675.

17.

Anomalous twin boundaries in two dimensional materials.

Rooney AP, Li Z, Zhao W, Gholinia A, Kozikov A, Auton G, Ding F, Gorbachev RV, Young RJ, Haigh SJ.

Nat Commun. 2018 Sep 5;9(1):3597. doi: 10.1038/s41467-018-06074-8.

18.

Personality, abnormal behaviour, and health: An evaluation of the welfare of police horses.

Schork IG, de Azevedo CS, Young RJ.

PLoS One. 2018 Sep 5;13(9):e0202750. doi: 10.1371/journal.pone.0202750. eCollection 2018.

19.

Real-world practice level data analysis confirms link between variability within Blood Glucose Monitoring Strip (BGMS) and glycosylated haemoglobin (HbA1c) in Type 1 Diabetes.

Heald AH, Livingston M, Fryer A, Cortes G, Anderson SG, Gadsby R, Laing I, Lunt M, Young RJ, Stedman M.

Int J Clin Pract. 2018 Dec;72(12):e13252. doi: 10.1111/ijcp.13252. Epub 2018 Aug 31.

PMID:
30168887
20.

Expanding the medicinal chemistry synthetic toolbox.

Boström J, Brown DG, Young RJ, Keserü GM.

Nat Rev Drug Discov. 2018 Oct;17(10):709-727. doi: 10.1038/nrd.2018.116. Epub 2018 Aug 24. Review. Erratum in: Nat Rev Drug Discov. 2018 Nov 28;17(12):922.

PMID:
30140018
21.

The Different Physical and Behavioural Characteristics of Zoo Mammals That Influence Their Response to Visitors.

Queiroz MB, Young RJ.

Animals (Basel). 2018 Aug 14;8(8). pii: E139. doi: 10.3390/ani8080139.

22.

Marked Response of a Hypermutated ACTH-Secreting Pituitary Carcinoma to Ipilimumab and Nivolumab.

Lin AL, Jonsson P, Tabar V, Yang TJ, Cuaron J, Beal K, Cohen M, Postow M, Rosenblum M, Shia J, DeAngelis LM, Taylor BS, Young RJ, Geer EB.

J Clin Endocrinol Metab. 2018 Oct 1;103(10):3925-3930. doi: 10.1210/jc.2018-01347.

PMID:
30085142
23.

Pretreatment dynamic contrast-enhanced MRI biomarkers correlate with progression-free survival in primary central nervous system lymphoma.

Hatzoglou V, Oh JH, Buck O, Lin X, Lee M, Shukla-Dave A, Young RJ, Peck KK, Vachha B, Holodny AI, Grommes C.

J Neurooncol. 2018 Nov;140(2):351-358. doi: 10.1007/s11060-018-2960-z. Epub 2018 Aug 2.

PMID:
30073640
24.

Designing of advanced smart medical stocking using stress-memory polymeric filaments for pressure control and massaging.

Narayana H, Hu J, Kumar B, Shang S, Ying M, Young RJ.

Mater Sci Eng C Mater Biol Appl. 2018 Oct 1;91:263-273. doi: 10.1016/j.msec.2018.05.026. Epub 2018 May 7.

PMID:
30033255
25.
26.

Discriminating radiation injury from recurrent tumor with [18F]PARPi and amino acid PET in mouse models.

Donabedian PL, Kossatz S, Engelbach JA, Jannetti SA, Carney B, Young RJ, Weber WA, Garbow JR, Reiner T.

EJNMMI Res. 2018 Jul 4;8(1):59. doi: 10.1186/s13550-018-0399-z.

27.

Urban Sloths: Public Knowledge, Opinions, and Interactions.

Pereira KF, Young RJ, Boere V, Silva IOE.

Animals (Basel). 2018 Jun 8;8(6). pii: E90. doi: 10.3390/ani8060090.

28.

Response to Scheel et al.

Reid VM, Dunn K, Donovan T, Young RJ.

Curr Biol. 2018 May 21;28(10):R596-R597. doi: 10.1016/j.cub.2018.03.048.

29.

The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GlmU.

Craggs PD, Mouilleron S, Rejzek M, de Chiara C, Young RJ, Field RA, Argyrou A, de Carvalho LPS.

Biochemistry. 2018 Jun 19;57(24):3387-3401. doi: 10.1021/acs.biochem.8b00121. Epub 2018 May 2.

30.

Multicenter Phase IB Trial of Carboxyamidotriazole Orotate and Temozolomide for Recurrent and Newly Diagnosed Glioblastoma and Other Anaplastic Gliomas.

Omuro A, Beal K, McNeill K, Young RJ, Thomas A, Lin X, Terziev R, Kaley TJ, DeAngelis LM, Daras M, Gavrilovic IT, Mellinghoff I, Diamond EL, McKeown A, Manne M, Caterfino A, Patel K, Bavisotto L, Gorman G, Lamson M, Gutin P, Tabar V, Chakravarty D, Chan TA, Brennan CW, Garrett-Mayer E, Karmali RA, Pentsova E.

J Clin Oncol. 2018 Jun 10;36(17):1702-1709. doi: 10.1200/JCO.2017.76.9992. Epub 2018 Apr 23.

31.

Validation of postoperative residual contrast-enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma.

Ellingson BM, Abrey LE, Nelson SJ, Kaufmann TJ, Garcia J, Chinot O, Saran F, Nishikawa R, Henriksson R, Mason WP, Wick W, Butowski N, Ligon KL, Gerstner ER, Colman H, de Groot J, Chang S, Mellinghoff I, Young RJ, Alexander BM, Colen R, Taylor JW, Arrillaga-Romany I, Mehta A, Huang RY, Pope WB, Reardon D, Batchelor T, Prados M, Galanis E, Wen PY, Cloughesy TF.

Neuro Oncol. 2018 Aug 2;20(9):1240-1250. doi: 10.1093/neuonc/noy053.

32.

Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations.

Young RJ, Leeson PD.

J Med Chem. 2018 Aug 9;61(15):6421-6467. doi: 10.1021/acs.jmedchem.8b00180. Epub 2018 Apr 25. Review.

PMID:
29620890
33.

Sodium-glucose co-transporter-2 inhibitors, the latest residents on the block: Impact on glycaemic control at a general practice level in England.

Heald AH, Fryer AA, Anderson SG, Livingston M, Lunt M, Davies M, Moreno GYC, Gadsby R, Young RJ, Stedman M.

Diabetes Obes Metab. 2018 Jul;20(7):1659-1669. doi: 10.1111/dom.13281. Epub 2018 Apr 17.

PMID:
29516618
34.

The Human Fetus Preferentially Engages with Face-like Visual Stimuli.

Reid VM, Dunn K, Young RJ, Amu J, Donovan T, Reissland N.

Curr Biol. 2018 Mar 5;28(5):824. doi: 10.1016/j.cub.2018.02.025. No abstract available.

35.

Unilateral radiotherapy treatment for p16/human papillomavirus-positive squamous cell carcinoma of unknown primary in the head and neck.

Tiong A, Rischin D, Young RJ, Herschtal A, Solomon B, D'Costa I, Fua T, Liu C, Coleman A, Kleid S, Dixon BJ, Corry J.

Laryngoscope. 2018 Sep;128(9):2076-2083. doi: 10.1002/lary.27131. Epub 2018 Feb 26.

PMID:
29481710
36.

Large-Area Heterostructures from Graphene and Encapsulated Colloidal Quantum Dots via the Langmuir-Blodgett Method.

Black A, Roberts J, Acebrón M, Bernardo-Gavito R, Alsharif G, Urbanos FJ, Juárez BH, Kolosov OV, Robinson BJ, Miranda R, Vázquez de Parga AL, Granados D, Young RJ.

ACS Appl Mater Interfaces. 2018 Feb 28;10(8):6805-6809. doi: 10.1021/acsami.7b17102. Epub 2018 Feb 19.

37.

Prognostic Significance of PD-L1+ and CD8+ Immune Cells in HPV+ Oropharyngeal Squamous Cell Carcinoma.

Solomon B, Young RJ, Bressel M, Urban D, Hendry S, Thai A, Angel C, Haddad A, Kowanetz M, Fua T, Corry J, Fox S, Rischin D.

Cancer Immunol Res. 2018 Jan 29. doi: 10.1158/2326-6066.CIR-17-0299. [Epub ahead of print]

PMID:
29378694
38.

Head and neck squamous cell carcinoma: Genomics and emerging biomarkers for immunomodulatory cancer treatments.

Solomon B, Young RJ, Rischin D.

Semin Cancer Biol. 2018 Oct;52(Pt 2):228-240. doi: 10.1016/j.semcancer.2018.01.008. Epub 2018 Jan 31. Review.

PMID:
29355614
39.

Genomic Heterogeneity Underlies Mixed Response to Tropomyosin Receptor Kinase Inhibition in Recurrent Glioma.

Schram AM, Jonsson P, Drilon A, Bale TA, Hechtman JF, Benayed R, Hanusch B, Young RJ, Grommes C, Ku N, Kaley T, Hyman DM, Taylor BS.

JCO Precis Oncol. 2018;2. doi: 10.1200/PO.18.00089. Epub 2018 Aug 8. No abstract available.

PMID:
31218270
40.

Extracting random numbers from quantum tunnelling through a single diode.

Bernardo-Gavito R, Bagci IE, Roberts J, Sexton J, Astbury B, Shokeir H, McGrath T, Noori YJ, Woodhead CS, Missous M, Roedig U, Young RJ.

Sci Rep. 2017 Dec 19;7(1):17879. doi: 10.1038/s41598-017-18161-9.

41.

Anti-angiogenic therapies for the treatment of angiosarcoma: a clinical update.

Young RJ, Woll PJ.

Memo. 2017;10(4):190-193. doi: 10.1007/s12254-017-0365-x. Epub 2017 Nov 7. Review.

42.

Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance.

Martin CA, Cullinane C, Kirby L, Abuhammad S, Lelliott EJ, Waldeck K, Young RJ, Brajanovski N, Cameron DP, Walker R, Sanij E, Poortinga G, Hannan RD, Pearson RB, Hicks RJ, McArthur GA, Sheppard KE.

Int J Cancer. 2018 May 15;142(10):2139-2152. doi: 10.1002/ijc.31220. Epub 2018 Jan 3.

43.

Room-Temperature Mid-Infrared Emission from Faceted InAsSb Multi Quantum Wells Embedded in InAs Nanowires.

Alhodaib A, Noori YJ, Carrington PJ, Sanchez AM, Thompson MD, Young RJ, Krier A, Marshall ARJ.

Nano Lett. 2018 Jan 10;18(1):235-240. doi: 10.1021/acs.nanolett.7b03977. Epub 2017 Dec 8.

PMID:
29191016
44.

Comparison of Four PD-L1 Immunohistochemical Assays in Lung Cancer.

Hendry S, Byrne DJ, Wright GM, Young RJ, Sturrock S, Cooper WA, Fox SB.

J Thorac Oncol. 2018 Mar;13(3):367-376. doi: 10.1016/j.jtho.2017.11.112. Epub 2017 Nov 23.

45.

Minimotif Miner 4: a million peptide minimotifs and counting.

Lyon KF, Cai X, Young RJ, Mamun AA, Rajasekaran S, Schiller MR.

Nucleic Acids Res. 2018 Jan 4;46(D1):D465-D470. doi: 10.1093/nar/gkx1085.

46.

Route to improving Type 1 diabetes mellitus glycaemic outcomes: real-world evidence taken from the National Diabetes Audit.

Heald AH, Livingston M, Fryer A, Moreno GYC, Malipatil N, Gadsby R, Ollier W, Lunt M, Stedman M, Young RJ.

Diabet Med. 2018 Jan;35(1):63-71. doi: 10.1111/dme.13541.

PMID:
29120503
47.

Background, current role, and potential applications of radiogenomics.

Pinker K, Shitano F, Sala E, Do RK, Young RJ, Wibmer AG, Hricak H, Sutton EJ, Morris EA.

J Magn Reson Imaging. 2018 Mar;47(3):604-620. doi: 10.1002/jmri.25870. Epub 2017 Nov 2. Review.

48.

Two-Step Electrochemical Intercalation and Oxidation of Graphite for the Mass Production of Graphene Oxide.

Cao J, He P, Mohammed MA, Zhao X, Young RJ, Derby B, Kinloch IA, Dryfe RAW.

J Am Chem Soc. 2017 Dec 6;139(48):17446-17456. doi: 10.1021/jacs.7b08515. Epub 2017 Nov 27.

49.

Diffusion Tensor Imaging Shows Corpus Callosum Differences between High-Grade Gliomas and Metastases.

Cho NS, Jenabi M, Arevalo-Perez J, Brennan N, Young RJ, Karimi S, Holodny AI, Peck KK.

J Neuroimaging. 2018 Mar;28(2):199-205. doi: 10.1111/jon.12478. Epub 2017 Oct 24.

PMID:
29064137
50.

Melanoma brain metastases treated with stereotactic radiosurgery and concurrent pembrolizumab display marked regression; efficacy and safety of combined treatment.

Anderson ES, Postow MA, Wolchok JD, Young RJ, Ballangrud Å, Chan TA, Yamada Y, Beal K.

J Immunother Cancer. 2017 Oct 17;5(1):76. doi: 10.1186/s40425-017-0282-x.

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