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Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes.

Bahne E, Sun EWL, Young RL, Hansen M, Sonne DP, Hansen JS, Rohde U, Liou AP, Jackson ML, de Fontgalland D, Rabbitt P, Hollington P, Sposato L, Due S, Wattchow DA, Rehfeld JF, Holst JJ, Keating DJ, Vilsbøll T, Knop FK.

JCI Insight. 2018 Dec 6;3(23). pii: 93936. doi: 10.1172/jci.insight.93936. [Epub ahead of print]


Identifying Patients for Whom Lung Cancer Screening Is Preference-Sensitive.

Young RP, Hopkins R.

Ann Intern Med. 2018 Dec 4;169(11):822-823. doi: 10.7326/L18-0555. No abstract available.


Patient Preference and Physician Perceptions of Patient Preference for Oral Pharmaceutical Formulations: Results from a Real-Life Survey.

MacKenzie-Smith L, Marchi P, Thorne H, Timeus S, Young R, Le Calvé P.

Inflamm Intest Dis. 2018 Nov;3(1):43-51. doi: 10.1159/000493346. Epub 2018 Oct 11.


Two-Dimensional Electronic Spectroscopy Reveals Excitation Energy-Dependent State Mixing during Singlet Fission in a Terrylenediimide Dimer.

Mandal A, Chen M, Foszcz E, Schultz JD, Kearns NM, Young RM, Zanni MT, Wasielewski MR.

J Am Chem Soc. 2018 Dec 2. doi: 10.1021/jacs.8b08627. [Epub ahead of print]


TLR signaling is activated in lymph-node resident CLL cells and is only partially inhibited by ibrutinib.

Dadashian EL, McAuley EM, Liu D, Shaffer AL, Young RM, Iyer JR, Kruhlak MJ, Staudt LM, Wiestner A, Herman SEM.

Cancer Res. 2018 Nov 29. pii: canres.0781.2018. doi: 10.1158/0008-5472.CAN-18-0781. [Epub ahead of print]


Novel PLAG1 Gene Rearrangement Distinguishes a Subset of Uterine Myxoid Leiomyosarcoma From Other Uterine Myxoid Mesenchymal Tumors.

Arias-Stella JA 3rd, Benayed R, Oliva E, Young RH, Hoang LN, Lee CH, Jungbluth AA, Frosina D, Soslow RA, Antonescu CR, Ladanyi M, Chiang S.

Am J Surg Pathol. 2018 Nov 27. doi: 10.1097/PAS.0000000000001196. [Epub ahead of print]


Expanding the medicinal chemistry synthetic toolbox.

Boström J, Brown DG, Young RJ, Keserü GM.

Nat Rev Drug Discov. 2018 Nov 28;17(12):922. doi: 10.1038/nrd.2018.217.


Erratum for Schooley et al., "Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection".

Schooley RT, Biswas B, Gill JJ, Hernandez-Morales A, Lancaster J, Lessor L, Barr JJ, Reed SL, Rohwer F, Benler S, Segall AM, Taplitz R, Smith DM, Kerr K, Kumaraswamy M, Nizet V, Lin L, McCauley MD, Strathdee SA, Benson CA, Pope RK, Leroux BM, Picel AC, Mateczun AJ, Cilwa KE, Regeimbal JM, Estrella LA, Wolfe DM, Henry MS, Quinones J, Salka S, Bishop-Lilly KA, Young R, Hamilton T.

Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e02221-18. doi: 10.1128/AAC.02221-18. Print 2018 Dec. No abstract available.


Species-Specific Transcriptional Regulation of Genes Involved in Nitric Oxide Production and Arginine Metabolism in Macrophages.

Young R, Bush SJ, Lefevre L, McCulloch MEB, Lisowski ZM, Muriuki C, Waddell LA, Sauter KA, Pridans C, Clark EL, Hume DA.

Immunohorizons. 2018 Jan 1;2(1):27-37. doi: 10.4049/immunohorizons.1700073.


Infections of the Ear.

Szmuilowicz J, Young R.

Emerg Med Clin North Am. 2019 Feb;37(1):1-9. doi: 10.1016/j.emc.2018.09.001. Review.


Testing the biosocial cognitive model of substance use in cannabis users referred to treatment.

Papinczak ZE, Connor JP, Feeney GFX, Harnett P, Young RM, Gullo MJ.

Drug Alcohol Depend. 2018 Nov 6;194:216-224. doi: 10.1016/j.drugalcdep.2018.09.032. [Epub ahead of print]


Quantitative imaging biomarkers alliance (QIBA) recommendations for improved precision of DWI and DCE-MRI derived biomarkers in multicenter oncology trials.

Shukla-Dave A, Obuchowski NA, Chenevert TL, Jambawalikar S, Schwartz LH, Malyarenko D, Huang W, Noworolski SM, Young RJ, Shiroishi MS, Kim H, Coolens C, Laue H, Chung C, Rosen M, Boss M, Jackson EF.

J Magn Reson Imaging. 2018 Nov 19. doi: 10.1002/jmri.26518. [Epub ahead of print] Review.


Challenges for school-based, anti-smoking education in China.

Zhao X, Young RM, White KM.

Lancet Child Adolesc Health. 2018 Nov 15. pii: S2352-4642(18)30338-9. doi: 10.1016/S2352-4642(18)30338-9. [Epub ahead of print] No abstract available.


Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains.

Boija A, Klein IA, Sabari BR, Dall'Agnese A, Coffey EL, Zamudio AV, Li CH, Shrinivas K, Manteiga JC, Hannett NM, Abraham BJ, Afeyan LK, Guo YE, Rimel JK, Fant CB, Schuijers J, Lee TI, Taatjes DJ, Young RA.

Cell. 2018 Nov 8. pii: S0092-8674(18)31398-9. doi: 10.1016/j.cell.2018.10.042. [Epub ahead of print]


Recessive host range mutants and unsusceptible cells that inactivate virions without genome penetration: ecological and technical implications.

Roznowski AP, Young RJ, Love SD, Andromita AA, Guzman VA, Wilch MH, Block A, McGill A, Lavelle M, Romanova A, Sekiguchi A, Wang M, Burch AD, Fane BA.

J Virol. 2018 Nov 14. pii: JVI.01767-18. doi: 10.1128/JVI.01767-18. [Epub ahead of print]


Phage single-gene lysis: Finding the weak spot in the bacterial cell wall.

Chamakura K, Young R.

J Biol Chem. 2018 Nov 12. pii: jbc.TM118.001773. doi: 10.1074/jbc.TM118.001773. [Epub ahead of print]


Scientific Business Abstracts of the 112th Annual Meeting of the Association of Physicians of Great Britain and Ireland.

Chauhan A, Lalor T, Watson S, Adams D, Farrah TE, Anand A, Kimmitt R, Mills NL, Webb DJ, Dhaun N, Kalla R, Adams A, Vatn S, Bonfliglio F, Nimmo E, Kennedy N, Ventham N, Vatn M, Ricanek P, Halfvarson J, Soderhollm J, Pierik M, Torkvist L, Gomollon F, Gut I, Jahnsen J, Satsangi J, Body R, Almashali M, McDowell G, Taylor P, Lacey A, Rees A, Ludgate, Dayan C, Lazarus J, Nelson S, Okosieme O, Corcoran D, Young R, Ciadella P, McCartney P, Bajrangee A, Hennigan B, Collison D, Carrick D, Shaukat A, Good R, Watkins S, McEntegart M, Watt J, Welsh P, Sattar N, McConnachie A, Oldroyd K, Berry C, Parks T, Auckland K, Mentzer AJ, Kado J, Mirabel MM, Kauwe JK, Robson KJ, Mittal B, Steer AC, Hill AVS, Akbar M, Forrester M, Virlan AT, Gilmour A, Wallace C, Paterson C, Reid D, Siebert S, Porter D, Liversidge J, McInnes I, Goodyear C, Athwal V, Pritchett J, Zaitoun A, Irving W, Guha IN, Hanley NA, Hanley KP, Briggs T, Reynolds J, Rice G, Bondet V, Bruce E, Crow Y, Duffy D, Parker B, Bruce I, Martin K, Pritchett J, Aoibheann Mullan M, Llewellyn J, Athwal V, Zeef L, Farrow S, Streuli C, Henderson N, Friedman S, Hanley N, Hanley KP.

QJM. 2018 Dec 1;111(12):920-924. doi: 10.1093/qjmed/hcy193. No abstract available.


The severity and associated comorbidities of retinopathy of prematurity among micro-premature infants with birth weights less than 750 grams.

Beck K, Young R, Read S, Harper H, Desireddi J, Harper CA.

J Neonatal Perinatal Med. 2018 Oct 30. doi: 10.3233/NPM-17158. [Epub ahead of print]


Composites with carbon nanotubes and graphene: An outlook.

Kinloch IA, Suhr J, Lou J, Young RJ, Ajayan PM.

Science. 2018 Nov 2;362(6414):547-553. doi: 10.1126/science.aat7439. Review.


Comparing the bacterial communities of wild and captive golden mantella frogs: Implications for amphibian conservation.

Passos LF, Garcia G, Young RJ.

PLoS One. 2018 Oct 31;13(10):e0205652. doi: 10.1371/journal.pone.0205652. eCollection 2018.


Singlet Fission in 9,10-Bis(phenylethynyl)anthracene Thin Films.

Bae YJ, Kang G, Malliakas CD, Nelson JN, Zhou J, Young RM, Wu YL, Van Duyne RP, Schatz GC, Wasielewski MR.

J Am Chem Soc. 2018 Nov 14;140(45):15140-15144. doi: 10.1021/jacs.8b07498. Epub 2018 Nov 1.


Multiple Luteinized Follicle Cysts of the Ovary in a Patient With a Pituitary Adenoma: Report of a Case and Review of the Literature.

Lebok P, Zuna RE, Holman LL, Young RH.

Int J Gynecol Pathol. 2018 Oct 24. doi: 10.1097/PGP.0000000000000555. [Epub ahead of print]


ADGRE1 (EMR1, F4/80) Is a Rapidly-Evolving Gene Expressed in Mammalian Monocyte-Macrophages.

Waddell LA, Lefevre L, Bush SJ, Raper A, Young R, Lisowski ZM, McCulloch MEB, Muriuki C, Sauter KA, Clark EL, Irvine KM, Pridans C, Hope JC, Hume DA.

Front Immunol. 2018 Oct 1;9:2246. doi: 10.3389/fimmu.2018.02246. eCollection 2018.


Role of Intestinal Bitter Sensing in Enteroendocrine Hormone Secretion and Metabolic Control.

Xie C, Wang X, Young RL, Horowitz M, Rayner CK, Wu T.

Front Endocrinol (Lausanne). 2018 Sep 27;9:576. doi: 10.3389/fendo.2018.00576. eCollection 2018. Review.


Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing.

Nantie LB, Young RE, Paltzer WG, Zhang Y, Johnson RL, Verheyden JM, Sun X.

Development. 2018 Nov 9;145(21). pii: dev163105. doi: 10.1242/dev.163105.


XXXI. Julius Schottlaender.

Pickel H, Brachtel E, Young RH.

Int J Gynecol Pathol. 2018 Nov;37(6):590-595. doi: 10.1097/PGP.0000000000000503. No abstract available.


Elastin Content and Distribution in Endothelial Keratoplasty Tissue Determines Direction of Scrolling.

Lewis PN, White TL, Feneck EM, Young RD, Meek KM.

Am J Ophthalmol. 2019 Jan;197:181-182. doi: 10.1016/j.ajo.2018.08.047. Epub 2018 Oct 5. No abstract available.


Isolation of Tryptanthrin and Reassessment of Evidence for Its Isobaric Isostere Wrightiadione in Plants of the Wrightia Genus.

Garcellano RC, Moinuddin SGA, Young RP, Zhou M, Bowden ME, Renslow RS, Yesiltepe Y, Thomas DG, Colby SM, Chouinard CD, Nagy G, Attah IK, Ibrahim YM, Ma R, Franzblau SG, Lewis NG, Aguinaldo AM, Cort JR.

J Nat Prod. 2018 Oct 8. doi: 10.1021/acs.jnatprod.8b00567. [Epub ahead of print]


Psychosocial Factors Associated with Healthy and Unhealthy Interpregnancy Intervals.

Young R, Lane WG, Stephens SB, Mayden BW, Fox RE.

Health Equity. 2018 Mar 1;2(1):22-29. doi: 10.1089/heq.2017.0017. eCollection 2018.


Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell.

Ruella M, Xu J, Barrett DM, Fraietta JA, Reich TJ, Ambrose DE, Klichinsky M, Shestova O, Patel PR, Kulikovskaya I, Nazimuddin F, Bhoj VG, Orlando EJ, Fry TJ, Bitter H, Maude SL, Levine BL, Nobles CL, Bushman FD, Young RM, Scholler J, Gill SI, June CH, Grupp SA, Lacey SF, Melenhorst JJ.

Nat Med. 2018 Oct;24(10):1499-1503. doi: 10.1038/s41591-018-0201-9. Epub 2018 Oct 1.


Marine chemical ecology in benthic environments.

Puglisi MP, Sneed JM, Ritson-Williams R, Young R.

Nat Prod Rep. 2018 Sep 28. doi: 10.1039/c8np00061a. [Epub ahead of print] Review.


Developing new health technologies for neglected diseases: a pipeline portfolio review and cost model.

Young R, Bekele T, Gunn A, Chapman N, Chowdhary V, Corrigan K, Dahora L, Martinez S, Permar S, Persson J, Rodriguez B, Schäferhoff M, Schulman K, Singh T, Terry RF, Yamey G.

Gates Open Res. 2018 Apr 26;2:23. doi: 10.12688/gatesopenres.12817.1.


TensorView: A software tool for displaying NMR tensors.

Young RP, Lewis CR, Yang C, Wang L, Harper JK, Mueller LJ.

Magn Reson Chem. 2018 Sep 19. doi: 10.1002/mrc.4793. [Epub ahead of print]


Minimotifs dysfunction is pervasive in neurodegenerative disorders.

Sharma S, Young RJ, Chen J, Chen X, Oh EC, Schiller MR.

Alzheimers Dement (N Y). 2018 Jul 25;4:414-432. doi: 10.1016/j.trci.2018.06.005. eCollection 2018.


Phage spanins: diversity, topological dynamics and gene convergence.

Kongari R, Rajaure M, Cahill J, Rasche E, Mijalis E, Berry J, Young R.

BMC Bioinformatics. 2018 Sep 15;19(1):326. doi: 10.1186/s12859-018-2342-8.


Assessment of the mutagenic potential of para-chloroaniline and aniline in the liver, spleen, and bone marrow of Big Blue® rats with micronuclei analysis in peripheral blood.

Koenig CM, Beevers C, Pant K, Young RR.

Environ Mol Mutagen. 2018 Dec;59(9):785-797. doi: 10.1002/em.22241. Epub 2018 Sep 14.


Covalent Radical Pairs as Spin Qubits: Influence of Rapid Electron Motion between Two Equivalent Sites on Spin Coherence.

Wu Y, Zhou J, Nelson JN, Young RM, Krzyaniak MD, Wasielewski MR.

J Am Chem Soc. 2018 Oct 10;140(40):13011-13021. doi: 10.1021/jacs.8b08105. Epub 2018 Sep 27.


Author Correction: Enhancer decommissioning by LSD1 during embryonic stem cell differentiation.

Whyte WA, Bilodeau S, Orlando DA, Hoke HA, Frampton GM, Foster CT, Cowley SM, Young RA.

Nature. 2018 Oct;562(7728):E24. doi: 10.1038/s41586-018-0487-2.


Water Dispersible Few-Layer Graphene Stabilized by a Novel Pyrene Derivative at Micromolar Concentration.

Cunha E, Proença MF, Pereira MG, Fernandes MJ, Young RJ, Strutyński K, Melle-Franco M, Gonzalez-Debs M, Lopes PE, Paiva MDC.

Nanomaterials (Basel). 2018 Aug 30;8(9). pii: E675. doi: 10.3390/nano8090675.


Transcriptome analysis reveals novel genes and immune networks dysregulated in veterans with PTSD.

Mehta D, Voisey J, Bruenig D, Harvey W, Morris CP, Lawford B, Young RM.

Brain Behav Immun. 2018 Nov;74:133-142. doi: 10.1016/j.bbi.2018.08.014. Epub 2018 Sep 4.


Screening Heroin Smokers Attending Community Drug Services for COPD.

Burhan H, Young R, Byrne T, Peat R, Furlong J, Renwick S, Elkin T, Oelbaum S, Walker PP.

Chest. 2018 Sep 4. pii: S0012-3692(18)32337-7. doi: 10.1016/j.chest.2018.08.1049. [Epub ahead of print]


Anomalous twin boundaries in two dimensional materials.

Rooney AP, Li Z, Zhao W, Gholinia A, Kozikov A, Auton G, Ding F, Gorbachev RV, Young RJ, Haigh SJ.

Nat Commun. 2018 Sep 5;9(1):3597. doi: 10.1038/s41467-018-06074-8.


Personality, abnormal behaviour, and health: An evaluation of the welfare of police horses.

Schork IG, de Azevedo CS, Young RJ.

PLoS One. 2018 Sep 5;13(9):e0202750. doi: 10.1371/journal.pone.0202750. eCollection 2018.


Cell regulation of collagen fibril macrostructure during corneal morphogenesis.

Koudouna E, Mikula E, Brown DJ, Young RD, Quantock AJ, Jester JV.

Acta Biomater. 2018 Oct 1;79:96-112. doi: 10.1016/j.actbio.2018.08.017. Epub 2018 Aug 29.


Real-world practice level data analysis confirms link between variability within Blood Glucose Monitoring Strip (BGMS) and glycosylated haemoglobin (HbA1c) in Type 1 Diabetes.

Heald AH, Livingston M, Fryer A, Cortes G, Anderson SG, Gadsby R, Laing I, Lunt M, Young RJ, Stedman M.

Int J Clin Pract. 2018 Dec;72(12):e13252. doi: 10.1111/ijcp.13252. Epub 2018 Aug 31.


Expanding the medicinal chemistry synthetic toolbox.

Boström J, Brown DG, Young RJ, Keserü GM.

Nat Rev Drug Discov. 2018 Oct;17(10):709-727. doi: 10.1038/nrd.2018.116. Epub 2018 Aug 24. Review. Erratum in: Nat Rev Drug Discov. 2018 Nov 28;17(12):922.


Localization and Regulation of the T1 Unimolecular Spanin.

Kongari R, Snowden J, Berry JD, Young R.

J Virol. 2018 Oct 29;92(22). pii: e00380-18. doi: 10.1128/JVI.00380-18. Print 2018 Nov 15.


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