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A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus.

Hobson-Peters J, Harrison JJ, Watterson D, Hazlewood JE, Vet LJ, Newton ND, Warrilow D, Colmant AMG, Taylor C, Huang B, Piyasena TBH, Chow WK, Setoh YX, Tang B, Nakayama E, Yan K, Amarilla AA, Wheatley S, Moore PR, Finger M, Kurucz N, Modhiran N, Young PR, Khromykh AA, Bielefeldt-Ohmann H, Suhrbier A, Hall RA.

Sci Transl Med. 2019 Dec 11;11(522). pii: eaax7888. doi: 10.1126/scitranslmed.aax7888.


Prevention of Recurrence After Recovery From a Major Depressive Episode With Antidepressant Medication Alone or in Combination With Cognitive Behavioral Therapy: A Phase 2 Randomized Clinical Trial.

DeRubeis RJ, Zajecka J, Shelton RC, Amsterdam JD, Fawcett J, Xu C, Young PR, Gallop R, Hollon SD.

JAMA Psychiatry. 2019 Dec 4. doi: 10.1001/jamapsychiatry.2019.3900. [Epub ahead of print]


Intra-host growth kinetics of dengue virus in the mosquito Aedes aegypti.

Novelo M, Hall MD, Pak D, Young PR, Holmes EC, McGraw EA.

PLoS Pathog. 2019 Dec 2;15(12):e1008218. doi: 10.1371/journal.ppat.1008218. eCollection 2019 Dec.


Efficient Delivery of Dengue Virus Subunit Vaccines to the Skin by Microprojection Arrays.

Muller DA, Depelsenaire ACI, Shannon AE, Watterson D, Corrie SR, Owens NS, Agyei-Yeboah C, Cheung STM, Zhang J, Fernando GJP, Kendall MAF, Young PR.

Vaccines (Basel). 2019 Nov 20;7(4). pii: E189. doi: 10.3390/vaccines7040189.


LAM-003, a new drug for treatment of tyrosine kinase inhibitor-resistant FLT3-ITD-positive AML.

Beeharry N, Landrette S, Gayle S, Hernandez M, Grotzke JE, Young PR, Beckett P, Zhang X, Carter BZ, Andreeff M, Halene S, Xu T, Rothberg J, Lichenstein H.

Blood Adv. 2019 Nov 26;3(22):3661-3673. doi: 10.1182/bloodadvances.2019001068.


Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon.

Tan YP, Xue Y, Savchenko AI, Houston SD, Modhiran N, McMillan CLD, Boyle GM, Bernhardt PV, Young PR, Watterson D, Williams CM.

J Nat Prod. 2019 Oct 25;82(10):2828-2834. doi: 10.1021/acs.jnatprod.9b00522. Epub 2019 Sep 25.


Cost implications of HIV retesting for verification in Africa.

Lasry A, Kalou MB, Young PR, Rurangirwa J, Parekh B, Behel S.

PLoS One. 2019 Jul 1;14(7):e0218936. doi: 10.1371/journal.pone.0218936. eCollection 2019.


Oncolytic Measles Virotherapy and Opposition to Measles Vaccination.

Russell SJ, Babovic-Vuksanovic D, Bexon A, Cattaneo R, Dingli D, Dispenzieri A, Deyle DR, Federspiel MJ, Fielding A, Galanis E, Lacy MQ, Leibovich BC, Liu MC, Muñoz-Alía M, Miest TC, Molina JR, Mueller S, Okuno SH, Packiriswamy N, Peikert T, Raffel C, Van Rhee F, Ungerechts G, Young PR, Zhou Y, Peng KW.

Mayo Clin Proc. 2019 Sep;94(9):1834-1839. doi: 10.1016/j.mayocp.2019.05.006. Epub 2019 Jun 22. Review.


Sustained Wolbachia-mediated blocking of dengue virus isolates following serial passage in Aedes aegypti cell culture.

Koh C, Audsley MD, Di Giallonardo F, Kerton EJ, Young PR, Holmes EC, McGraw EA.

Virus Evol. 2019 Jun 8;5(1):vez012. doi: 10.1093/ve/vez012. eCollection 2019 Jan.


Dual targeting of dengue virus virions and NS1 protein with the heparan sulfate mimic PG545.

Modhiran N, Gandhi NS, Wimmer N, Cheung S, Stacey K, Young PR, Ferro V, Watterson D.

Antiviral Res. 2019 Aug;168:121-127. doi: 10.1016/j.antiviral.2019.05.004. Epub 2019 May 11.


Inactivation of yellow fever virus in plasma after treatment with methylene blue and visible light and in platelet concentrates following treatment with ultraviolet C light.

Faddy HM, Fryk JJ, Hall RA, Young PR, Reichenberg S, Tolksdorf F, Sumian C, Gravemann U, Seltsam A, Marks DC.

Transfusion. 2019 Jul;59(7):2223-2227. doi: 10.1111/trf.15332. Epub 2019 May 3.


Stachyonic Acid: A Dengue Virus Inhibitor from Basilicum polystachyon.

Tan YP, Houston SD, Modhiran N, Savchenko AI, Boyle GM, Young PR, Watterson D, Williams CM.

Chemistry. 2019 Apr 17;25(22):5664-5667. doi: 10.1002/chem.201900591. Epub 2019 Mar 29.


Determinants of Zika virus host tropism uncovered by deep mutational scanning.

Setoh YX, Amarilla AA, Peng NYG, Griffiths RE, Carrera J, Freney ME, Nakayama E, Ogawa S, Watterson D, Modhiran N, Nanyonga FE, Torres FJ, Slonchak A, Periasamy P, Prow NA, Tang B, Harrison J, Hobson-Peters J, Cuddihy T, Cooper-White J, Hall RA, Young PR, Mackenzie JM, Wolvetang E, Bloom JD, Suhrbier A, Khromykh AA.

Nat Microbiol. 2019 May;4(5):876-887. doi: 10.1038/s41564-019-0399-4. Epub 2019 Mar 18.


Linking Terpene Synthases to Sesquiterpene Metabolism in Grapevine Flowers.

Smit SJ, Vivier MA, Young PR.

Front Plant Sci. 2019 Feb 21;10:177. doi: 10.3389/fpls.2019.00177. eCollection 2019.


Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine.

Kharenko OA, Patel RG, Brown SD, Calosing C, White A, Lakshminarasimhan D, Suto RK, Duffy BC, Kitchen DB, McLure KG, Hansen HC, van der Horst EH, Young PR.

J Med Chem. 2018 Sep 27;61(18):8202-8211. doi: 10.1021/acs.jmedchem.8b00666. Epub 2018 Sep 13.


Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion.

Löber U, Hobbs M, Dayaram A, Tsangaras K, Jones K, Alquezar-Planas DE, Ishida Y, Meers J, Mayer J, Quedenau C, Chen W, Johnson RN, Timms P, Young PR, Roca AL, Greenwood AD.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):8609-8614. doi: 10.1073/pnas.1807598115. Epub 2018 Aug 6.


Communication Ambassadors-an Australian Social Media Initiative to Develop Communication Skills in Early Career Scientists.

Wang JTH, Power CJ, Kahler CM, Lyras D, Young PR, Iredell J, Robins-Browne R.

J Microbiol Biol Educ. 2018 Mar 30;19(1). pii: 19.1.25. doi: 10.1128/jmbe.v19i1.1428. eCollection 2018.


Viral Entry and NS1 as Potential Antiviral Drug Targets.

de Silva AM, Rey FA, Young PR, Hilgenfeld R, Vasudevan SG.

Adv Exp Med Biol. 2018;1062:107-113. doi: 10.1007/978-981-10-8727-1_8. Review.


Plugging the Leak in Dengue Shock.

Watterson D, Modhiran N, Muller DA, Stacey KJ, Young PR.

Adv Exp Med Biol. 2018;1062:89-106. doi: 10.1007/978-981-10-8727-1_7. Review.


Arboviruses: A Family on the Move.

Young PR.

Adv Exp Med Biol. 2018;1062:1-10. doi: 10.1007/978-981-10-8727-1_1. Review.


Antibody-Binding, Antifouling Surface Coatings Based on Recombinant Expression of Zwitterionic EK Peptides.

Walker JA, Robinson KJ, Munro C, Gengenbach T, Muller DA, Young PR, Lua LHL, Corrie SR.

Langmuir. 2019 Feb 5;35(5):1266-1272. doi: 10.1021/acs.langmuir.8b00810. Epub 2018 Jun 19.


Cell division and turgor mediate enhanced plant growth in Arabidopsis plants treated with the bacterial signalling molecule lumichrome.

Pholo M, Coetzee B, Maree HJ, Young PR, Lloyd JR, Kossmann J, Hills PN.

Planta. 2018 Aug;248(2):477-488. doi: 10.1007/s00425-018-2916-8. Epub 2018 May 17.


Complete genome of Aedes aegypti anphevirus in the Aag2 mosquito cell line.

Di Giallonardo F, Audsley MD, Shi M, Young PR, McGraw EA, Holmes EC.

J Gen Virol. 2018 Jun;99(6):832-836. doi: 10.1099/jgv.0.001079. Epub 2018 May 9.


Multispecialty retrospective review of the clinical utility of pelvic magnetic resonance imaging in the setting of pelvic pain.

Moore JR, Pathak RA, Snowden C, Bolan CW, Young PR, Broderick GA.

Transl Androl Urol. 2017 Dec;6(6):1155-1158. doi: 10.21037/tau.2017.10.02.


Structural and Functional Characterization of a Cross-Reactive Dengue Virus Neutralizing Antibody that Recognizes a Cryptic Epitope.

Li J, Watterson D, Chang CW, Che XY, Li XQ, Ericsson DJ, Qiu LW, Cai JP, Chen J, Fry SR, Cheung STM, Cooper MA, Young PR, Kobe B.

Structure. 2018 Jan 2;26(1):51-59.e4. doi: 10.1016/j.str.2017.11.017. Epub 2017 Dec 14.


The Heptad Repeat C Domain of the Respiratory Syncytial Virus Fusion Protein Plays a Key Role in Membrane Fusion.

Bermingham IM, Chappell KJ, Watterson D, Young PR.

J Virol. 2018 Jan 30;92(4). pii: e01323-17. doi: 10.1128/JVI.01323-17. Print 2018 Feb 15.


High-density microprojection array delivery to rat skin of low doses of trivalent inactivated poliovirus vaccine elicits potent neutralising antibody responses.

Muller DA, Fernando GJP, Owens NS, Agyei-Yeboah C, Wei JCJ, Depelsenaire ACI, Forster A, Fahey P, Weldon WC, Oberste MS, Young PR, Kendall MAF.

Sci Rep. 2017 Oct 3;7(1):12644. doi: 10.1038/s41598-017-13011-0.


RVX-297, a BET Bromodomain Inhibitor, Has Therapeutic Effects in Preclinical Models of Acute Inflammation and Autoimmune Disease.

Jahagirdar R, Attwell S, Marusic S, Bendele A, Shenoy N, McLure KG, Gilham D, Norek K, Hansen HC, Yu R, Tobin J, Wagner GS, Young PR, Wong NCW, Kulikowski E.

Mol Pharmacol. 2017 Dec;92(6):694-706. doi: 10.1124/mol.117.110379. Epub 2017 Sep 29.


Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children.

Brealey JC, Chappell KJ, Galbraith S, Fantino E, Gaydon J, Tozer S, Young PR, Holt PG, Sly PD.

Respirology. 2018 Feb;23(2):220-227. doi: 10.1111/resp.13179. Epub 2017 Sep 15.


Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein.

Jaberolansar N, Chappell KJ, Watterson D, Bermingham IM, Toth I, Young PR, Skwarczynski M.

Sci Rep. 2017 Sep 11;7(1):11130. doi: 10.1038/s41598-017-10415-w.


The Transcriptional Responses and Metabolic Consequences of Acclimation to Elevated Light Exposure in Grapevine Berries.

du Plessis K, Young PR, Eyéghé-Bickong HA, Vivier MA.

Front Plant Sci. 2017 Jul 20;8:1261. doi: 10.3389/fpls.2017.01261. eCollection 2017.


Reduction of Zika virus infectivity in platelet concentrates after treatment with ultraviolet C light and in plasma after treatment with methylene blue and visible light.

Fryk JJ, Marks DC, Hobson-Peters J, Watterson D, Hall RA, Young PR, Reichenberg S, Tolksdorf F, Sumian C, Gravemann U, Seltsam A, Faddy HM.

Transfusion. 2017 Nov;57(11):2677-2682. doi: 10.1111/trf.14256. Epub 2017 Jul 17.


Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay.

Lebani K, Jones ML, Watterson D, Ranzoni A, Traves RJ, Young PR, Mahler SM.

PLoS One. 2017 Jul 6;12(7):e0180669. doi: 10.1371/journal.pone.0180669. eCollection 2017.


Clinical and Laboratory Diagnosis of Dengue Virus Infection.

Muller DA, Depelsenaire AC, Young PR.

J Infect Dis. 2017 Mar 1;215(suppl_2):S89-S95. doi: 10.1093/infdis/jiw649. Review.


Computational Identification of Antibody Epitopes on the Dengue Virus NS1 Protein.

Jones ML, Legge FS, Lebani K, Mahler SM, Young PR, Watterson D, Treutlein HR, Zeng J.

Molecules. 2017 Apr 10;22(4). pii: E607. doi: 10.3390/molecules22040607.


Impact of Direction of Unloading Influence on Template Rate of Perceived Exertion.

Greer BK, Young PR, Thompson B, Rickert BJ, Moran MF.

J Strength Cond Res. 2018 Dec;32(12):3398-3404. doi: 10.1519/JSC.0000000000001846.


Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6.

Modhiran N, Watterson D, Blumenthal A, Baxter AG, Young PR, Stacey KJ.

Immunol Cell Biol. 2017 May;95(5):491-495. doi: 10.1038/icb.2017.5. Epub 2017 Feb 21.


Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG.

Pyankov OV, Setoh YX, Bodnev SA, Edmonds JH, Pyankova OG, Pyankov SA, Pali G, Belford S, Lu L, La M, Lovrecz G, Volchkova VA, Chappell KJ, Watterson D, Marsh G, Young PR, Agafonov AA, Farmer JF, Volchkov VE, Suhrbier A, Khromykh AA.

Sci Rep. 2017 Feb 3;7:41537. doi: 10.1038/srep41537.


Investigating the Effect of Substrate Materials on Wearable Immunoassay Performance.

Lee KT, Coffey JW, Robinson KJ, Muller DA, Grøndahl L, Kendall MA, Young PR, Corrie SR.

Langmuir. 2017 Jan 24;33(3):773-782. doi: 10.1021/acs.langmuir.6b03933. Epub 2017 Jan 11.


Product release is rate-limiting for catalytic processing by the Dengue virus protease.

Shannon AE, Pedroso MM, Chappell KJ, Watterson D, Liebscher S, Kok WM, Fairlie DP, Schenk G, Young PR.

Sci Rep. 2016 Nov 29;6:37539. doi: 10.1038/srep37539.


Phylogenetic Diversity of Koala Retrovirus within a Wild Koala Population.

Chappell KJ, Brealey JC, Amarilla AA, Watterson D, Hulse L, Palmieri C, Johnston SD, Holmes EC, Meers J, Young PR.

J Virol. 2017 Jan 18;91(3). pii: e01820-16. doi: 10.1128/JVI.01820-16. Print 2017 Feb 1.


Impact of Minimally Invasive Benign Prostatic Hyperplasia Therapies on 30- and 90-Day Postoperative Office Encounters.

Pathak RA, Broderick GA, Igel TC, Petrou SP, Young PR, Wehle MJ, Heckman MG, Diehl NN, Vargas ER, Shah K, Thiel DD.

Urology. 2017 Jan;99:186-191. doi: 10.1016/j.urology.2016.10.015. Epub 2016 Oct 19.


Riboflavin and ultraviolet light: impact on dengue virus infectivity.

Faddy HM, Fryk JJ, Watterson D, Young PR, Modhiran N, Muller DA, Keil SD, Goodrich RP, Marks DC.

Vox Sang. 2016 Oct;111(3):235-241. doi: 10.1111/vox.12414. Epub 2016 Jun 9.


Data on gene and protein expression changes induced by apabetalone (RVX-208) in ex vivo treated human whole blood and primary hepatocytes.

Wasiak S, Gilham D, Tsujikawa LM, Halliday C, Norek K, Patel RG, McLure KG, Young PR, Gordon A, Kulikowski E, Johansson J, Sweeney M, Wong NC.

Data Brief. 2016 Jul 29;8:1280-8. doi: 10.1016/j.dib.2016.07.047. eCollection 2016 Sep.


How Can the Health System Retain Women in HIV Treatment for a Lifetime? A Discrete Choice Experiment in Ethiopia and Mozambique.

Kruk ME, Riley PL, Palma AM, Adhikari S, Ahoua L, Arnaldo C, Belo DF, Brusamento S, Cumba LI, Dziuban EJ, El-Sadr WM, Gutema Y, Habtamu Z, Heller T, Kidanu A, Langa J, Mahagaja E, McCarthy CF, Melaku Z, Shodell D, Tsiouris F, Young PR, Rabkin M.

PLoS One. 2016 Aug 23;11(8):e0160764. doi: 10.1371/journal.pone.0160764. eCollection 2016.


Dengue and chikungunya viruses in plasma are effectively inactivated after treatment with methylene blue and visible light.

Fryk JJ, Marks DC, Hobson-Peters J, Prow NA, Watterson D, Hall RA, Young PR, Reichenberg S, Sumian C, Faddy HM.

Transfusion. 2016 Sep;56(9):2278-85. doi: 10.1111/trf.13729. Epub 2016 Jul 25.


Field-Grown Grapevine Berries Use Carotenoids and the Associated Xanthophyll Cycles to Acclimate to UV Exposure Differentially in High and Low Light (Shade) Conditions.

Joubert C, Young PR, Eyéghé-Bickong HA, Vivier MA.

Front Plant Sci. 2016 Jun 10;7:786. doi: 10.3389/fpls.2016.00786. eCollection 2016.


RVX-297- a novel BD2 selective inhibitor of BET bromodomains.

Kharenko OA, Gesner EM, Patel RG, Norek K, White A, Fontano E, Suto RK, Young PR, McLure KG, Hansen HC.

Biochem Biophys Res Commun. 2016 Aug 12;477(1):62-67. doi: 10.1016/j.bbrc.2016.06.021. Epub 2016 Jun 6.


Notice of Retraction and Replacement. Hollon et al. Effect of cognitive therapy with antidepressant medications vs antidepressants alone on the rate of recovery in major depressive disorder: a randomized clinical trial. JAMA Psychiatry. 2014;71(10):1157-1164.

Hollon SD, DeRubeis RJ, Fawcett J, Amsterdam JD, Shelton RC, Zajecka J, Young PR, Gallop R.

JAMA Psychiatry. 2016 Jun 1;73(6):639-40. doi: 10.1001/jamapsychiatry.2016.0756. No abstract available.

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