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Items: 49

1.

Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses.

Dantoft W, Martínez-Vicente P, Jafali J, Pérez-Martínez L, Martin K, Kotzamanis K, Craigon M, Auer M, Young NT, Walsh P, Marchant A, Angulo A, Forster T, Ghazal P.

Front Immunol. 2017 Sep 25;8:1146. doi: 10.3389/fimmu.2017.01146. eCollection 2017.

2.

Novel mRNA-specific effects of ribosome drop-off on translation rate and polysome profile.

Bonnin P, Kern N, Young NT, Stansfield I, Romano MC.

PLoS Comput Biol. 2017 May 30;13(5):e1005555. doi: 10.1371/journal.pcbi.1005555. eCollection 2017 May.

3.

Leukocyte Ig-Like receptor B1 restrains dendritic cell function through increased expression of the NF-κB regulator ABIN1/TNIP1.

Khanolkar RC, Kalogeropoulos M, Lawrie A, Roghanian A, Vickers MA, Young NT.

J Leukoc Biol. 2016 Oct;100(4):737-746. Epub 2016 Apr 29.

PMID:
27129285
4.

Killer immunoglobulin-like receptor gene repertoire influences viral load of primary human cytomegalovirus infection in renal transplant patients.

Jones DC, Peacock S, Hughes D, Traherne JA, Allen RL, Barnardo MC, Friend P, Taylor CJ, Fuggle S, Trowsdale J, Young NT.

Genes Immun. 2014 Dec;15(8):562-8. doi: 10.1038/gene.2014.53. Epub 2014 Sep 25.

PMID:
25253288
5.

Filament-associated TSGA10 protein is expressed in professional antigen presenting cells and interacts with vimentin.

Roghanian A, Jones DC, Pattisapu JV, Wolfe J, Young NT, Behnam B.

Cell Immunol. 2010;265(2):120-6. doi: 10.1016/j.cellimm.2010.07.012. Epub 2010 Aug 2.

PMID:
20797700
6.

Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes.

Jones DC, Roghanian A, Brown DP, Chang C, Allen RL, Trowsdale J, Young NT.

Eur J Immunol. 2009 Nov;39(11):3195-206. doi: 10.1002/eji.200839080.

7.

Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G.

Eagle RA, Flack G, Warford A, Martínez-Borra J, Jafferji I, Traherne JA, Ohashi M, Boyle LH, Barrow AD, Caillat-Zucman S, Young NT, Trowsdale J.

PLoS One. 2009;4(2):e4503. doi: 10.1371/journal.pone.0004503. Epub 2009 Feb 18. Erratum in: PLoS ONE. 2009;4(3). doi: 10.1371/annotation/34238ee8-5128-4f1d-9ae2-6906c9764e49. PLoS ONE. 2009;4(3). doi: 10.1371/annotation/8501cd33-6c9e-437c-9ea1-f96fbb4140d6.

8.

Increased expression and intramitochondrial translocation of cyclophilin-D associates with increased vulnerability of the permeability transition pore to stress-induced opening during compensated ventricular hypertrophy.

Matas J, Young NT, Bourcier-Lucas C, Ascah A, Marcil M, Deschepper CF, Burelle Y.

J Mol Cell Cardiol. 2009 Mar;46(3):420-30. doi: 10.1016/j.yjmcc.2008.10.020. Epub 2008 Nov 6.

PMID:
19094991
9.

The inhibitory receptor LILRB1 modulates the differentiation and regulatory potential of human dendritic cells.

Young NT, Waller EC, Patel R, Roghanian A, Austyn JM, Trowsdale J.

Blood. 2008 Mar 15;111(6):3090-6. Epub 2007 Dec 19.

PMID:
18094328
10.

Killer Ig-like receptor (KIR) genotype and HLA ligand combinations in ulcerative colitis susceptibility.

Jones DC, Edgar RS, Ahmad T, Cummings JR, Jewell DP, Trowsdale J, Young NT.

Genes Immun. 2006 Oct;7(7):576-82. Epub 2006 Aug 24.

PMID:
16929347
11.

Nature of allelic sequence polymorphism at the KIR3DL3 locus.

Jones DC, Hiby SE, Moffett A, Trowsdale J, Young NT.

Immunogenetics. 2006 Aug;58(8):614-27. Epub 2006 Jul 6.

PMID:
16823588
12.

Does memory improve with age? CD85j (ILT-2/LIR-1) expression on CD8 T cells correlates with 'memory inflation' in human cytomegalovirus infection.

Northfield J, Lucas M, Jones H, Young NT, Klenerman P.

Immunol Cell Biol. 2005 Apr;83(2):182-8.

PMID:
15748215
13.

Immunobiology of natural killer lymphocytes in transplantation.

Young NT.

Transplantation. 2004 Jul 15;78(1):1-6. Review.

PMID:
15257030
14.

Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D.

Bacon L, Eagle RA, Meyer M, Easom N, Young NT, Trowsdale J.

J Immunol. 2004 Jul 15;173(2):1078-84.

15.

Natural killer receptors and graft-vs.-host/ graft-vs.-leukaemia reactions.

Jones DC, Young NT.

Vox Sang. 2004 Jul;87 Suppl 2:15-7. Review. No abstract available.

PMID:
15209869
16.

Human platelet alloantigens (HPAs): PCR-SSP genotyping of a UK population for 15 HPA alleles.

Jones DC, Bunce M, Fuggle SV, Young NT, Marshall SE.

Eur J Immunogenet. 2003 Dec;30(6):415-9.

PMID:
14675395
17.

Natural killer receptor repertoires in transplantation.

Jones DC, Young NT.

Eur J Immunogenet. 2003 Jun;30(3):169-76. Review.

PMID:
12786992
18.

Comprehensive hereditary hemochromatosis genotyping.

Jones DC, Young NT, Pigott C, Fuggle SV, Barnardo MC, Marshall SE, Bunce M.

Tissue Antigens. 2002 Dec;60(6):481-8.

PMID:
12542741
19.

Frequency and phenotype of circulating Valpha24/Vbeta11 double-positive natural killer T cells during hepatitis C virus infection.

Lucas M, Gadola S, Meier U, Young NT, Harcourt G, Karadimitris A, Coumi N, Brown D, Dusheiko G, Cerundolo V, Klenerman P.

J Virol. 2003 Feb;77(3):2251-7.

20.

KIR expression shapes cytotoxic repertoires: a developmental program of survival.

Young NT, Uhrberg M.

Trends Immunol. 2002 Feb;23(2):71-5. Review.

PMID:
11929129
21.

Comparison of chimpanzee and human leukocyte Ig-like receptor genes reveals framework and rapidly evolving genes.

Canavez F, Young NT, Guethlein LA, Rajalingam R, Khakoo SI, Shum BP, Parham P.

J Immunol. 2001 Nov 15;167(10):5786-94.

22.

Conserved organization of the ILT/LIR gene family within the polymorphic human leukocyte receptor complex.

Young NT, Canavez F, Uhrberg M, Shum BP, Parham P.

Immunogenetics. 2001 May-Jun;53(4):270-8.

PMID:
11491530
23.

Permissible and immunogenic HLA-A mismatches: cytotoxic T-cell precursor frequencies reflect graft survival data.

Roelen DL, Stobbe I, Young NT, van Bree SP, Doxiadis II, Oudshoorn M, Morris PJ, Wood KJ, Claas FH.

Hum Immunol. 2001 Jul;62(7):661-7.

PMID:
11423171
24.
26.

KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains.

Vilches C, Rajalingam R, Uhrberg M, Gardiner CM, Young NT, Parham P.

J Immunol. 2000 Jun 1;164(11):5797-804.

27.

Kir genes, killer cells and clinical transplantation.

Young NT.

Transplantation. 1999 Dec 15;68(11):1626-8. Review. No abstract available.

PMID:
10609935
28.

A human monoclonal antibody against HLA-Cw1 and a human monoclonal antibody against an HLA-A locus determinant derived from a single uniparous female.

Mulder A, Kardol MJ, Uit het Broek CM, Tanke-Visser J, Young NT, Claas FH.

Tissue Antigens. 1998 Oct;52(4):393-6.

PMID:
9820605
29.

Expression of HLA class I antigens in transporter associated with antigen processing (TAP)-deficient mutant cell lines.

Young NT, Mulder A, Cerundolo V, Claas FH, Welsh KI.

Tissue Antigens. 1998 Oct;52(4):368-73.

PMID:
9820600
30.

Independent contributions of HLA epitopes and killer inhibitory receptor expression to the functional alloreactive specificity of natural killer cells.

Young NT, Rust NA, Dallman MJ, Cerundolo V, Morris PJ, Welsh KI.

Hum Immunol. 1998 Nov;59(11):700-12.

PMID:
9796738
32.

HLA-DRB1 amino acid disparity is the major stimulus of interleukin-2 production by alloreactive helper T-lymphocytes.

Young NT, Roelen DL, Dallman MJ, Morris PJ, Welsh KI.

Immunogenetics. 1998 Mar;47(4):310-7.

PMID:
9472067
33.

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C.

Braud VM, Allan DS, O'Callaghan CA, Söderström K, D'Andrea A, Ogg GS, Lazetic S, Young NT, Bell JI, Phillips JH, Lanier LL, McMichael AJ.

Nature. 1998 Feb 19;391(6669):795-9.

PMID:
9486650
34.

Molecular HLA typing--the brave new world.

Bunce M, Young NT, Welsh KI.

Transplantation. 1997 Dec 15;64(11):1505-13. Review. No abstract available.

PMID:
9415548
35.

Effect of one-HLA-haplotype-matched and HLA-mismatched blood transfusions on recipient T lymphocyte allorepertoires.

Young NT, Roelen DL, Iggo N, Gray DW, Roake JA, Graham V, Wood KJ, Dallman MJ, Welsh KI, Morris PJ.

Transplantation. 1997 Apr 27;63(8):1160-5.

PMID:
9133479
36.

Killer cell inhibitory receptor interactions with HLA class I molecules: implications for alloreactivity and transplantation.

Young NT, Bunce M, Morris PJ, Welsh KI.

Hum Immunol. 1997 Jan;52(1):1-11. Review.

PMID:
9021404
37.

Primary alloreactive cytotoxic T-lymphocytes are not commonly restricted by self-HLA class I antigens.

Young NT, Roelen DL, Wood KJ, Welsh KI, Morris PJ, Dallman MJ.

Hum Immunol. 1996 Sep 15;50(1):38-46.

PMID:
8872173
38.

Enumeration of human alloreactive helper T lymphocyte precursor frequencies by limiting dilution analysis of interleukin-2 production.

Young NT, Roelen DL, Dallman MJ, Wood KJ, Morris PJ, Welsh KI.

J Immunol Methods. 1996 Sep 9;195(1-2):33-41.

PMID:
8814317
39.

Semi-allogeneic (F1) versus fully allogeneic blood transfusions: differences in their ability to induce specific immunological unresponsiveness.

Roelen DL, Dover EL, Niimi M, Young NT, Morris PJ, Wood KJ.

Eur J Immunol. 1996 Jul;26(7):1468-74.

PMID:
8766548
40.

Immunogenetic analysis of HLA-DR10 homozygous individuals.

Young NT, Thompson J, Gibson K, Dewar K, Darke C.

Eur J Immunogenet. 1995 Apr;22(2):191-7.

PMID:
7605777
41.

Immunoglobulin allotype frequencies in responders and nonresponders to the Rh(D) antigen.

Young NT, Street J, Darke C.

Exp Clin Immunogenet. 1995;12(2):88-91.

PMID:
7576720
42.
43.

Molecular characterization of the HLA-DR2LUM haplotype.

Young NT, Darke C.

Tissue Antigens. 1994 Jan;43(1):28-33.

PMID:
7912857
44.
45.

"Molecular crossmatching" for allogeneic bone marrow transplants by DNA single-strand polymorphism analysis.

Young NT, Darke C.

Lancet. 1993 Jan 16;341(8838):183-4. No abstract available.

PMID:
8093789
46.

An apparent homozygous example of the HLA-DR2 variant, DR2.4(LUM).

Young NT, Mills MT, James S, Darke C.

Tissue Antigens. 1991 Jul;38(1):41-4. No abstract available.

PMID:
1681601
47.

Severe intravascular haemolysis in a renal transplant recipient due to anti-B of donor origin.

Orchard J, Young NT, Smith C, Thomas S, Darke C.

Vox Sang. 1990;59(3):172-5.

PMID:
2264320
48.

A miniaturised method for immunoglobulin allotype serology.

Young NT, Street J, Darke C.

J Immunol Methods. 1989 Aug 15;122(1):143-7.

PMID:
2760475
49.

Bromelain solutions for use in automated anti-D quantitation: a potential hazard.

Bowell PJ, Cully BJ, Young NT.

Med Lab Sci. 1988 Apr;45(2):146-50. No abstract available.

PMID:
3145381

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