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Differential visible spectral influence on carbon metabolism in heterotrophic marine flavobacteria.

Hameed A, Lai WA, Shahina M, Stothard P, Young LS, Lin SY, Sridhar KR, Young CC.

FEMS Microbiol Ecol. 2020 Jan 21. pii: fiaa011. doi: 10.1093/femsec/fiaa011. [Epub ahead of print]


CD40L membrane retention enhances the immunostimulatory effects of CD40 ligation.

Elmetwali T, Salman A, Wei W, Hussain SA, Young LS, Palmer DH.

Sci Rep. 2020 Jan 15;10(1):342. doi: 10.1038/s41598-019-57293-y.


Implementing Patient-Derived Xenografts to Assess the Effectiveness of Cyclin-Dependent Kinase Inhibitors in Glioblastoma.

Noonan JJ, Jarzabek M, Lincoln FA, Cavanagh BL, Pariag AR, Juric V, Young LS, Ligon KL, Jahns H, Zheleva D, Prehn JHM, Rehm M, Byrne AT, Murphy BM.

Cancers (Basel). 2019 Dec 12;11(12). pii: E2005. doi: 10.3390/cancers11122005.


A novel panel of differentially-expressed microRNAs in breast cancer brain metastasis may predict patient survival.

Giannoudis A, Clarke K, Zakaria R, Varešlija D, Farahani M, Rainbow L, Platt-Higgins A, Ruthven S, Brougham KA, Rudland PS, Jenkinson MD, Young LS, Falciani F, Palmieri C.

Sci Rep. 2019 Dec 6;9(1):18518. doi: 10.1038/s41598-019-55084-z.


Draft genome sequence reveals co-occurrence of multiple antimicrobial resistance and plant probiotic traits in rice root endophytic strain Burkholderia sp. LS-044 affiliated to Burkholderia cepacia complex.

Hameed A, Shahina M, Lai WA, Stothard P, Young LS, Lin SY, Young CC.

J Glob Antimicrob Resist. 2019 Dec 3;20:28-30. doi: 10.1016/j.jgar.2019.11.017. [Epub ahead of print]


Discovery of selective, antimetastatic and anti-cancer stem cell metallohelices via post-assembly modification.

Song H, Rogers NJ, Allison SJ, Brabec V, Bridgewater H, Kostrhunova H, Markova L, Phillips RM, Pinder EC, Shepherd SL, Young LS, Zajac J, Scott P.

Chem Sci. 2019 Jul 18;10(37):8547-8557. doi: 10.1039/c9sc02651g. eCollection 2019 Oct 7.


BET Inhibition as a Rational Therapeutic Strategy for Invasive Lobular Breast Cancer.

Walsh L, Haley KE, Moran B, Mooney B, Tarrant F, Madden SF, Di Grande A, Fan Y, Das S, Rueda OM, Dowling CM, Varešlija D, Chin SF, Linn S, Young LS, Jirström K, Crown JP, Bernards R, Caldas C, Gallagher WM, O'Connor DP, Ní Chonghaile T.

Clin Cancer Res. 2019 Dec 1;25(23):7139-7150. doi: 10.1158/1078-0432.CCR-19-0713. Epub 2019 Aug 13.


A case study in the functional consequences of scaling the sizes of realistic cortical models.

Joglekar MR, Chariker L, Shapley R, Young LS.

PLoS Comput Biol. 2019 Jul 23;15(7):e1007198. doi: 10.1371/journal.pcbi.1007198. eCollection 2019 Jul.


Altered Steroid Milieu in AI-Resistant Breast Cancer Facilitates AR Mediated Gene-Expression Associated with Poor Response to Therapy.

Creevey L, Bleach R, Madden SF, Toomey S, Bane FT, Varešlija D, Hill AD, Young LS, McIlroy M.

Mol Cancer Ther. 2019 Oct;18(10):1731-1743. doi: 10.1158/1535-7163.MCT-18-0791. Epub 2019 Jul 9.


An etiological role for the Epstein-Barr virus in the pathogenesis of classical Hodgkin lymphoma.

Murray PG, Young LS.

Blood. 2019 Aug 15;134(7):591-596. doi: 10.1182/blood.2019000568. Epub 2019 Jun 11. Review.


Photoactive platinum(iv) complex conjugated to a cancer-cell-targeting cyclic peptide.

Shi H, Wang Q, Venkatesh V, Feng G, Young LS, Romero-Canelón I, Zeng M, Sadler PJ.

Dalton Trans. 2019 Jun 28;48(24):8560-8564. doi: 10.1039/c9dt00909d. Epub 2019 May 31.


An SIQ delay differential equations model for disease control via isolation.

Ruschel S, Pereira T, Yanchuk S, Young LS.

J Math Biol. 2019 Jul;79(1):249-279. doi: 10.1007/s00285-019-01356-1. Epub 2019 Apr 29.


Consequences of delays and imperfect implementation of isolation in epidemic control.

Young LS, Ruschel S, Yanchuk S, Pereira T.

Sci Rep. 2019 Mar 5;9(1):3505. doi: 10.1038/s41598-019-39714-0.


Cleavage of the extracellular domain of junctional adhesion molecule-A is associated with resistance to anti-HER2 therapies in breast cancer settings.

Leech AO, Vellanki SH, Rutherford EJ, Keogh A, Jahns H, Hudson L, O'Donovan N, Sabri S, Abdulkarim B, Sheehan KM, Kay EW, Young LS, Hill ADK, Smith YE, Hopkins AM.

Breast Cancer Res. 2018 Nov 20;20(1):140. doi: 10.1186/s13058-018-1064-1.


Rhythm and Synchrony in a Cortical Network Model.

Chariker L, Shapley R, Young LS.

J Neurosci. 2018 Oct 3;38(40):8621-8634. doi: 10.1523/JNEUROSCI.0675-18.2018. Epub 2018 Aug 17.


Low cleaved caspase-7 levels indicate unfavourable outcome across all breast cancers.

Lindner AU, Lucantoni F, Varešlija D, Resler A, Murphy BM, Gallagher WM, Hill ADK, Young LS, Prehn JHM.

J Mol Med (Berl). 2018 Oct;96(10):1025-1037. doi: 10.1007/s00109-018-1675-0. Epub 2018 Aug 1.


How well do reduced models capture the dynamics in models of interacting neurons?

Li Y, Chariker L, Young LS.

J Math Biol. 2019 Jan;78(1-2):83-115. doi: 10.1007/s00285-018-1268-0. Epub 2018 Jul 30.


The Dynamic Roles of TGF-β Signalling in EBV-Associated Cancers.

Velapasamy S, Dawson CW, Young LS, Paterson IC, Yap LF.

Cancers (Basel). 2018 Jul 27;10(8). pii: E247. doi: 10.3390/cancers10080247. Review.


Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets.

Varešlija D, Priedigkeit N, Fagan A, Purcell S, Cosgrove N, O'Halloran PJ, Ward E, Cocchiglia S, Hartmaier R, Castro CA, Zhu L, Tseng GC, Lucas PC, Puhalla SL, Brufsky AM, Hamilton RL, Mathew A, Leone JP, Basudan A, Hudson L, Dwyer R, Das S, O'Connor DP, Buckley PG, Farrell M, Hill ADK, Oesterreich S, Lee AV, Young LS.

J Natl Cancer Inst. 2019 Apr 1;111(4):388-398. doi: 10.1093/jnci/djy110.


Correction to: Nongenomic oestrogen signalling in oestrogen receptor negative breast cancer cells: a role for the angiotensin II receptor AT1.

Lim KT, Cosgrave N, Hill AD, Young LS.

Breast Cancer Res. 2018 Jun 20;20(1):61. doi: 10.1186/s13058-018-0987-x.


The EBV-Encoded Oncoprotein, LMP1, Induces an Epithelial-to-Mesenchymal Transition (EMT) via Its CTAR1 Domain through Integrin-Mediated ERK-MAPK Signalling.

Morris MA, Laverick L, Wei W, Davis AM, O'Neill S, Wood L, Wright J, Dawson CW, Young LS.

Cancers (Basel). 2018 May 1;10(5). pii: E130. doi: 10.3390/cancers10050130.


Epigenome-wide SRC-1-Mediated Gene Silencing Represses Cellular Differentiation in Advanced Breast Cancer.

Ward E, Varešlija D, Charmsaz S, Fagan A, Browne AL, Cosgrove N, Cocchiglia S, Purcell SP, Hudson L, Das S, O'Connor D, O'Halloran PJ, Sims AH, Hill AD, Young LS.

Clin Cancer Res. 2018 Aug 1;24(15):3692-3703. doi: 10.1158/1078-0432.CCR-17-2615. Epub 2018 Mar 22.


Suboptimal Opioid Prescribing: A Practice Change Project.

Young LS, Crausman RS, Fulton JP.

R I Med J (2013). 2018 Mar 1;101(2):41-44.


Network analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer.

Browne AL, Charmsaz S, Varešlija D, Fagan A, Cosgrove N, Cocchiglia S, Purcell S, Ward E, Bane F, Hudson L, Hill AD, Carroll JS, Redmond AM, Young LS.

Oncogene. 2018 Apr;37(15):2008-2021. doi: 10.1038/s41388-017-0042-x. Epub 2018 Jan 25.


EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma.

Lung RW, Hau PM, Yu KH, Yip KY, Tong JH, Chak WP, Chan AW, Lam KH, Lo AK, Tin EK, Chau SL, Pang JC, Kwan JS, Busson P, Young LS, Yap LF, Tsao SW, To KF, Lo KW.

J Pathol. 2018 Apr;244(4):394-407. doi: 10.1002/path.5018. Epub 2018 Feb 16.


Slipping and holding minds: A psychosocial analysis of maternal subjectivity in relation to childhood disability.

Young LS, Berry J.

Afr J Disabil. 2016 Jul 26;5(1):266. doi: 10.4102/ajod.v5i1.266. eCollection 2016.


Trauma and BMI Mortality.

Brahmbhatt TS, Hernon M, Siegert CJ, Plauché L, Young LS, Burke P.

Curr Obes Rep. 2017 Jun;6(2):211-216. doi: 10.1007/s13679-017-0264-9. Review.


The role of metabolic reprogramming in γ-herpesvirus-associated oncogenesis.

Lo AK, Dawson CW, Young LS, Lo KW.

Int J Cancer. 2017 Oct 15;141(8):1512-1521. doi: 10.1002/ijc.30795. Epub 2017 Jun 7. Review.


S100β as a serum marker in endocrine resistant breast cancer.

Charmsaz S, Hughes É, Bane FT, Tibbitts P, McIlroy M, Byrne C, Cocchiglia S, McBryan J, Hennessy BT, Dwyer RM, Kerin MJ, Hill AD, Young LS.

BMC Med. 2017 Apr 12;15(1):79. doi: 10.1186/s12916-017-0836-2.



Willard DL, Young LS, He X, Braverman LE, Pearce EN.

Endocr Pract. 2017 Jul;23(7):775-779. doi: 10.4158/EP161692.OR. Epub 2017 Mar 23.


Orientation Selectivity from Very Sparse LGN Inputs in a Comprehensive Model of Macaque V1 Cortex.

Chariker L, Shapley R, Young LS.

J Neurosci. 2016 Dec 7;36(49):12368-12384.


Epstein-Barr virus: more than 50 years old and still providing surprises.

Young LS, Yap LF, Murray PG.

Nat Rev Cancer. 2016 Dec;16(12):789-802. doi: 10.1038/nrc.2016.92. Epub 2016 Sep 30. Review.


Nutritional status and feeding practices in gastrointestinal surgery patients at Bach Mai Hospital, Hanoi, Vietnam.

Young LS, Huong PT, Lam NT, Thu NN, Van HT, Hanh NL, Tuyen le D, Lien DT, Hoc TH, Tuyet CT, Anh NQ, Henry EG, Lenders CM, Gura KM, Bigornia SJ, Apovian CM, Ziegler TR.

Asia Pac J Clin Nutr. 2016;25(3):513-20. doi: 10.6133/apjcn.092015.15.


Dynamic Signal Tracking in a Simple V1 Spiking Model.

Lajoie G, Young LS.

Neural Comput. 2016 Sep;28(9):1985-2010. doi: 10.1162/NECO_a_00868. Epub 2016 Jul 8.


Epstein-Barr virus and carcinomas: rare association of the virus with gastric adenocarcinomas.

Rowlands DC, Ito M, Mangham DC, Reynolds G, Herbst H, Hallissey MT, Fielding JW, Newbold KM, Jones EL, Young LS, Niedobitek G.

Br J Cancer. 2016 Jun 14;114(12):e15. doi: 10.1038/bjc.2016.156. Epub 2016 May 26. No abstract available.


Actibacterium ureilyticum sp. nov., isolated from seawater.

Lin SY, Young CC, Hameed A, Liu YC, Hsu YH, Chung WC, Young LS.

Int J Syst Evol Microbiol. 2016 Aug;66(8):2769-2773. doi: 10.1099/ijsem.0.001052. Epub 2016 Mar 31.


The Epstein-Barr virus encoded LMP1 oncoprotein modulates cell adhesion via regulation of activin A/TGFβ and β1 integrin signalling.

Morris MA, Dawson CW, Laverick L, Davis AM, Dudman JP, Raveenthiraraj S, Ahmad Z, Yap LF, Young LS.

Sci Rep. 2016 Jan 19;6:19533. doi: 10.1038/srep19533.


Adaptation to AI Therapy in Breast Cancer Can Induce Dynamic Alterations in ER Activity Resulting in Estrogen-Independent Metastatic Tumors.

Varešlija D, McBryan J, Fagan A, Redmond AM, Hao Y, Sims AH, Turnbull A, Dixon JM, Ó Gaora P, Hudson L, Purcell S, Hill AD, Young LS.

Clin Cancer Res. 2016 Jun 1;22(11):2765-77. doi: 10.1158/1078-0432.CCR-15-1583. Epub 2016 Jan 13.


Control of epidemics on complex networks: Effectiveness of delayed isolation.

Pereira T, Young LS.

Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Aug;92(2):022822. Epub 2015 Aug 31.


Traumatic panhypopituitarism resulting in acute adrenal crisis.

Ham PB, Cunningham AJ, Mentzer CJ, Ahmad A, Young LS, Abuzeid AM.

J Trauma Acute Care Surg. 2015 Sep;79(3):484-9. doi: 10.1097/TA.0000000000000771. Review.


Thalassocola ureilytica gen. nov., sp. nov., of the family Phyllobacteriaceae isolated from seawater.

Lin SY, Hameed A, Young CC, Liu YC, Hsu YH, Chung WC, Young LS.

Int J Syst Evol Microbiol. 2015 Nov;65(11):4100-4106. doi: 10.1099/ijsem.0.000544. Epub 2015 Aug 20.


Transcriptomic Profiling of Sequential Tumors from Breast Cancer Patients Provides a Global View of Metastatic Expression Changes Following Endocrine Therapy.

McBryan J, Fagan A, McCartan D, Bane FT, Varešlija D, Cocchiglia S, Byrne C, Bolger J, McIlroy M, Hudson L, Tibbitts P, Gaora PÓ, Hill AD, Young LS.

Clin Cancer Res. 2015 Dec 1;21(23):5371-9. doi: 10.1158/1078-0432.CCR-14-2155. Epub 2015 Aug 3.


Activation of the FGFR1 signalling pathway by the Epstein-Barr virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells.

Lo AK, Dawson CW, Young LS, Ko CW, Hau PM, Lo KW.

J Pathol. 2015 Oct;237(2):238-48. doi: 10.1002/path.4575. Epub 2015 Aug 3.


CD44 increases the efficiency of distant metastasis of breast cancer.

McFarlane S, Coulter JA, Tibbits P, O'Grady A, McFarlane C, Montgomery N, Hill A, McCarthy HO, Young LS, Kay EW, Isacke CM, Waugh DJ.

Oncotarget. 2015 May 10;6(13):11465-76.


Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection.

Palser AL, Grayson NE, White RE, Corton C, Correia S, Ba Abdullah MM, Watson SJ, Cotten M, Arrand JR, Murray PG, Allday MJ, Rickinson AB, Young LS, Farrell PJ, Kellam P.

J Virol. 2015 May;89(10):5222-37. doi: 10.1128/JVI.03614-14. Epub 2015 Mar 18.


Oricola cellulosilytica gen. nov., sp. nov., a cellulose-degrading bacterium of the family Phyllobacteriaceae isolated from surface seashore water, and emended descriptions of Mesorhizobium loti and Phyllobacterium myrsinacearum.

Hameed A, Shahina M, Lai WA, Lin SY, Young LS, Liu YC, Hsu YH, Young CC.

Antonie Van Leeuwenhoek. 2015 Mar;107(3):759-71. doi: 10.1007/s10482-014-0370-6. Epub 2015 Jan 8.


Pseudomonas matsuisoli sp. nov., isolated from a soil sample.

Lin SY, Hameed A, Hung MH, Liu YC, Hsu YH, Young LS, Young CC.

Int J Syst Evol Microbiol. 2015 Mar;65(Pt 3):902-9. doi: 10.1099/ijs.0.000035. Epub 2014 Dec 18.


Epstein-Barr virus and nasopharyngeal carcinoma.

Young LS, Dawson CW.

Chin J Cancer. 2014 Dec;33(12):581-90. doi: 10.5732/cjc.014.10197. Epub 2014 Nov 21.


Epstein-Barr virus at 50-future perspectives.

Young LS.

Chin J Cancer. 2014 Nov;33(11):527-8. doi: 10.5732/cjc.014.10208.

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