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Items: 1 to 50 of 109

1.

Rash on the thigh.

Cheng MW, Goldbach H, Young LC.

J Fam Pract. 2019 Sep;68(7):415-416.

PMID:
31532818
2.

EAST multicenter trial of simulation-based team training for pediatric trauma: Resuscitation task completion is highly variable during simulated traumatic brain injury resuscitation.

Jensen AR, Bullaro F, Falcone RA, Daugherty M, Young LC, McLaughlin C, Park C, Lane C, Prince JM, Scherzer DJ, Maa T, Dunn J, Wining L, Hess J, Santos MC, O'Neill J, Katz E, O'Bosky K, Young T, Christison-Lagay E, Ahmed O, Burd RS, Auerbach M.

Am J Surg. 2019 Aug 5. pii: S0002-9610(19)30926-2. doi: 10.1016/j.amjsurg.2019.07.037. [Epub ahead of print]

PMID:
31421895
3.

SHOC2 complex-driven RAF dimerization selectively contributes to ERK pathway dynamics.

Boned Del Río I, Young LC, Sari S, Jones GG, Ringham-Terry B, Hartig N, Rejnowicz E, Lei W, Bhamra A, Surinova S, Rodriguez-Viciana P.

Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13330-13339. doi: 10.1073/pnas.1902658116. Epub 2019 Jun 18.

4.

SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers.

Jones GG, Del Río IB, Sari S, Sekerim A, Young LC, Hartig N, Areso Zubiaur I, El-Bahrawy MA, Hynds RE, Lei W, Molina-Arcas M, Downward J, Rodriguez-Viciana P.

Nat Commun. 2019 Jun 10;10(1):2532. doi: 10.1038/s41467-019-10367-x.

5.

SHOC2-MRAS-PP1 complex positively regulates RAF activity and contributes to Noonan syndrome pathogenesis.

Young LC, Hartig N, Boned Del Río I, Sari S, Ringham-Terry B, Wainwright JR, Jones GG, McCormick F, Rodriguez-Viciana P.

Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10576-E10585. doi: 10.1073/pnas.1720352115. Epub 2018 Oct 22.

6.

Impact of simulation-based training on perceived provider confidence in acute multidisciplinary pediatric trauma resuscitation.

McLaughlin CM, Wieck MM, Barin EN, Rake A, Burke RV, Roesly HB, Young LC, Chang TP, Cleek EA, Morton I, Goodhue CJ, Burd RS, Ford HR, Upperman JS, Jensen AR.

Pediatr Surg Int. 2018 Dec;34(12):1353-1362. doi: 10.1007/s00383-018-4361-y. Epub 2018 Oct 15.

7.

Acquired Sleep-Related Hypermotor Epilepsy with Disrupted White Matter Tracts Assessed by Multishell Diffusion Magnetic Resonance Imaging.

Tchopev ZN, Yeh PH, Morgan GW, Meyer E, Wolf JM, Ollinger JM, Riedy GP, Young LC.

Front Neurol. 2018 Jan 22;9:6. doi: 10.3389/fneur.2018.00006. eCollection 2018.

8.

Self-assessment of team performance using T-NOTECHS in simulated pediatric trauma resuscitation is not consistent with expert assessment.

Wieck MM, McLaughlin C, Chang TP, Rake A, Park C, Lane C, Burke RV, Young LC, Cleek EA, Morton I, Goodhue CJ, Burd RS, Ford HR, Upperman JS, Jensen AR.

Am J Surg. 2018 Sep;216(3):630-635. doi: 10.1016/j.amjsurg.2018.01.010. Epub 2018 Feb 1.

PMID:
29366483
9.

MRAS: A Close but Understudied Member of the RAS Family.

Young LC, Rodriguez-Viciana P.

Cold Spring Harb Perspect Med. 2018 Dec 3;8(12). pii: a033621. doi: 10.1101/cshperspect.a033621. Review.

PMID:
29311130
10.

Palmoplantar keratoderma in Slurp1/Slurp2 double-knockout mice.

Allan CM, Heizer PJ, Jung CJ, Tu Y, Tran D, Young LC, Fong LG, de Jong PJ, Beigneux AP, Young SG.

J Dermatol Sci. 2018 Jan;89(1):85-87. doi: 10.1016/j.jdermsci.2017.08.014. Epub 2017 Sep 28. No abstract available.

11.

Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers.

Anthony NG, Baiget J, Berretta G, Boyd M, Breen D, Edwards J, Gamble C, Gray AI, Harvey AL, Hatziieremia S, Ho KH, Huggan JK, Lang S, Llona-Minguez S, Luo JL, McIntosh K, Paul A, Plevin RJ, Robertson MN, Scott R, Suckling CJ, Sutcliffe OB, Young LC, Mackay SP.

J Med Chem. 2017 Aug 24;60(16):7043-7066. doi: 10.1021/acs.jmedchem.7b00484. Epub 2017 Aug 15.

12.

Formulation of Nonionic Surfactant Vesicles (NISV) Prepared by Microfluidics for Therapeutic Delivery of siRNA into Cancer Cells.

Obeid MA, Elburi A, Young LC, Mullen AB, Tate RJ, Ferro VA.

Mol Pharm. 2017 Jul 3;14(7):2450-2458. doi: 10.1021/acs.molpharmaceut.7b00352. Epub 2017 Jun 8.

13.

Metabolomic Profiling of the Synergistic Effects of Melittin in Combination with Cisplatin on Ovarian Cancer Cells.

Alonezi S, Tusiimire J, Wallace J, Dufton MJ, Parkinson JA, Young LC, Clements CJ, Park JK, Jeon JW, Ferro VA, Watson DG.

Metabolites. 2017 Apr 14;7(2). pii: E14. doi: 10.3390/metabo7020014.

14.

A hypomorphic Egfr allele does not ameliorate the palmoplantar keratoderma caused by SLURP1 deficiency.

Allan CM, Tran D, Tu Y, Heizer PJ, Young LC, Fong LG, Beigneux AP, Young SG.

Exp Dermatol. 2017 Nov;26(11):1134-1136. doi: 10.1111/exd.13363. Epub 2017 Jul 27.

15.

Structure-Activity Relationships of Small Molecule Autotaxin Inhibitors with a Discrete Binding Mode.

Miller LM, Keune WJ, Castagna D, Young LC, Duffy EL, Potjewyd F, Salgado-Polo F, Engel García P, Semaan D, Pritchard JM, Perrakis A, Macdonald SJ, Jamieson C, Watson AJ.

J Med Chem. 2017 Jan 26;60(2):722-748. doi: 10.1021/acs.jmedchem.6b01597. Epub 2017 Jan 5.

16.

Qualitative assessment of simulation-based training for pediatric trauma resuscitation.

Burke RV, Demeter NE, Goodhue CJ, Roesly H, Rake A, Young LC, Chang TP, Cleek E, Morton I, Upperman JS, Jensen AR.

Surgery. 2017 May;161(5):1357-1366. doi: 10.1016/j.surg.2016.09.023. Epub 2016 Nov 11.

PMID:
27842918
17.

Metabolomic Profiling of the Effects of Melittin on Cisplatin Resistant and Cisplatin Sensitive Ovarian Cancer Cells Using Mass Spectrometry and Biolog Microarray Technology.

Alonezi S, Tusiimire J, Wallace J, Dufton MJ, Parkinson JA, Young LC, Clements CJ, Park JK, Jeon JW, Ferro VA, Watson DG.

Metabolites. 2016 Oct 13;6(4). pii: E35.

18.

Flight paths of seabirds soaring over the ocean surface enable measurement of fine-scale wind speed and direction.

Yonehara Y, Goto Y, Yoda K, Watanuki Y, Young LC, Weimerskirch H, Bost CA, Sato K.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9039-44. doi: 10.1073/pnas.1523853113. Epub 2016 Jul 25.

19.

Synthesis and Evaluation of a New Series of 8-(2-Nitroaryl)Xanthines as Adenosine Receptor Ligands.

Bansal R, Kumar G, Rohilla S, Klotz KN, Kachler S, Young LC, Harvey AL.

Drug Dev Res. 2016 Aug;77(5):241-50. doi: 10.1002/ddr.21317. Epub 2016 Jul 12.

PMID:
27404511
20.

Radical Isomerization and Cycloisomerization Initiated by H• Transfer.

Li G, Kuo JL, Han A, Abuyuan JM, Young LC, Norton JR, Palmer JH.

J Am Chem Soc. 2016 Jun 22;138(24):7698-704. doi: 10.1021/jacs.6b03509. Epub 2016 Jun 7.

PMID:
27167594
21.

Palmoplantar Keratoderma in Slurp2-Deficient Mice.

Allan CM, Procaccia S, Tran D, Tu Y, Barnes RH 2nd, Larsson M, Allan BB, Young LC, Hong C, Tontonoz P, Fong LG, Young SG, Beigneux AP.

J Invest Dermatol. 2016 Feb;136(2):436-443. doi: 10.1016/j.jid.2015.11.003. Epub 2015 Nov 18.

22.

Changes in biomarkers of bone turnover in an aripiprazole add-on or switching study.

Lodhi RJ, Masand S, Malik A, Shivakumar K, McAllister VD, O'Keane V, Young LC, Heald AH, Sherwood RA, Aitchison KJ.

Schizophr Res. 2016 Feb;170(2-3):245-51. doi: 10.1016/j.schres.2015.12.007. Epub 2016 Jan 12.

PMID:
26792297
23.

Using Molecular Networking for Microbial Secondary Metabolite Bioprospecting.

Purves K, Macintyre L, Brennan D, Hreggviðsson GÓ, Kuttner E, Ásgeirsdóttir ME, Young LC, Green DH, Edrada-Ebel R, Duncan KR.

Metabolites. 2016 Jan 8;6(1). pii: E2. doi: 10.3390/metabo6010002.

24.

Sclerodermoid lesions in a patient with multiple transplants and porphyria cutanea tarda.

Rubin AG, Fox LP, Sako EY, Young LC.

Dermatol Online J. 2015 Jun 16;21(6). pii: 13030/qt5969167b.

PMID:
26158360
25.

Papules on the face and body.

Anastasiou C, Scumpia PO, Smart C, Young LC.

Cutis. 2015 May;95(5):E22-4. No abstract available.

PMID:
26057515
26.

A case of Morfan syndrome.

Hiscox B, Hu J, Young LC.

Cutis. 2015 Mar;95(3):E20-1. No abstract available.

PMID:
25844790
27.

Waxy indurated plaques on the eyelids.

Aleshin MA, Custis TD, Gharavi NM, Goh C, Young LC.

Cutis. 2015 Feb;95(2):E24-7. No abstract available.

PMID:
25750974
28.

Relationship between inflammatory and coagulation biomarkers and cardiac autonomic function in HIV-infected individuals.

Young LC, Roediger MP, Grandits G, Baker J, Somboonwit C, Williams I, Lundgren JD, Neaton JD, Soliman EZ.

Biomark Med. 2014;8(9):1073-83. doi: 10.2217/bmm.14.27.

29.

Microhemorrhage is an early event in the pulmonary fibrotic disease of PECAM-1 deficient FVB/n mice.

Lishnevsky M, Young LC, Woods SJ, Groshong SD, Basaraba RJ, Gilchrist JM, Higgins DM, Gonzalez-Juarrero M, Bass TA, Muller WA, Schenkel AR.

Exp Mol Pathol. 2014 Aug;97(1):128-36. doi: 10.1016/j.yexmp.2014.06.008. Epub 2014 Jun 24.

30.

As the egg turns: monitoring egg attendance behavior in wild birds using novel data logging technology.

Shaffer SA, Clatterbuck CA, Kelsey EC, Naiman AD, Young LC, VanderWerf EA, Warzybok P, Bradley R, Jahncke J, Bower GC.

PLoS One. 2014 Jun 2;9(6):e97898. doi: 10.1371/journal.pone.0097898. eCollection 2014.

31.

Localized bullous fixed drug eruption following yellow fever vaccine.

Sako EY, Rubin A, Young LC.

J Am Acad Dermatol. 2014 May;70(5):e113-4. doi: 10.1016/j.jaad.2013.11.040. No abstract available.

32.

Nutrition: the future of melanoma prevention?

Tong LX, Young LC.

J Am Acad Dermatol. 2014 Jul;71(1):151-60. doi: 10.1016/j.jaad.2014.01.910. Epub 2014 Mar 20. Review.

PMID:
24656410
33.

Palmoplantar keratoderma along with neuromuscular and metabolic phenotypes in Slurp1-deficient mice.

Adeyo O, Allan BB, Barnes RH 2nd, Goulbourne CN, Tatar A, Tu Y, Young LC, Weinstein MM, Tontonoz P, Fong LG, Beigneux AP, Young SG.

J Invest Dermatol. 2014 Jun;134(6):1589-1598. doi: 10.1038/jid.2014.19. Epub 2014 Jan 17.

34.

Aspirin use and melanoma risk: a review of the literature.

Famenini S, Young LC.

J Am Acad Dermatol. 2014 Jan;70(1):187-91. doi: 10.1016/j.jaad.2013.09.045. Review.

PMID:
24355265
35.

An unusual presentation and distribution of generalized eruptive syringomas.

Chow C, Gharavi NM, Smart CN, Yashar S, Young LC.

Skinmed. 2013 Sep-Oct;11(5):311-2.

PMID:
24340475
36.

Adaptive value of same-sex pairing in Laysan albatross.

Young LC, VanderWerf EA.

Proc Biol Sci. 2013 Nov 27;281(1775):20132473. doi: 10.1098/rspb.2013.2473. Print 2014 Jan 22.

37.

The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression.

Young LC, Hendzel MJ.

Biochem Cell Biol. 2013 Dec;91(6):369-77. doi: 10.1139/bcb-2012-0054. Epub 2012 Dec 5. Review.

PMID:
24219278
38.

An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth.

Young LC, Hartig N, Muñoz-Alegre M, Oses-Prieto JA, Durdu S, Bender S, Vijayakumar V, Vietri Rudan M, Gewinner C, Henderson S, Jathoul AP, Ghatrora R, Lythgoe MF, Burlingame AL, Rodriguez-Viciana P.

Mol Cell. 2013 Dec 12;52(5):679-92. doi: 10.1016/j.molcel.2013.10.004. Epub 2013 Nov 7.

39.

Polycomb repressive complex 2 contributes to DNA double-strand break repair.

Campbell S, Ismail IH, Young LC, Poirier GG, Hendzel MJ.

Cell Cycle. 2013 Aug 15;12(16):2675-83. doi: 10.4161/cc.25795. Epub 2013 Jul 29.

40.

Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation.

Young LC, McDonald DW, Hendzel MJ.

J Biol Chem. 2013 Jul 19;288(29):21376-88. doi: 10.1074/jbc.M113.491514. Epub 2013 Jun 6.

41.

Efficacy of medical therapy in treatment of chronic rhinosinusitis.

Young LC, Stow NW, Zhou L, Douglas RG.

Allergy Rhinol (Providence). 2012;3(1):e8-e12. doi: 10.2500/ar.2012.3.0027. Epub 2012 May 18.

42.

Chemical leukoderma from hair dye containing para-phenylenediamine.

Farsani TT, Jalian HR, Young LC.

Dermatitis. 2012 Jul-Aug;23(4):181-2. doi: 10.1097/DER.0b013e318260d5cd. No abstract available.

PMID:
22828262
43.

A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A(1) receptors and enhances consolidation of step-down avoidance.

Harvey AL, Young LC, Kornisiuk E, Snitcofsky M, Colettis N, Blanco C, Jerusalinsky D, Jamieson AG, Hartley RC, Stone TW.

Behav Brain Res. 2012 Oct 1;234(2):184-91. doi: 10.1016/j.bbr.2012.06.023. Epub 2012 Jun 28.

PMID:
22750535
44.

Light acts on the zebrafish circadian clock to suppress rhythmic mitosis and cell proliferation.

Tamai TK, Young LC, Cox CA, Whitmore D.

J Biol Rhythms. 2012 Jun;27(3):226-36. doi: 10.1177/0748730412440861.

PMID:
22653891
45.

Mohs' micrographic surgery as treatment for squamous dysplasia of the nail unit.

Young LC, Tuxen AJ, Goodman G.

Australas J Dermatol. 2012 May;53(2):123-7. doi: 10.1111/j.1440-0960.2011.00813.x. Epub 2011 Sep 9.

PMID:
22571561
46.

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites.

Mallette FA, Mattiroli F, Cui G, Young LC, Hendzel MJ, Mer G, Sixma TK, Richard S.

EMBO J. 2012 Apr 18;31(8):1865-78. doi: 10.1038/emboj.2012.47. Epub 2012 Feb 28.

47.

A case of lichen planus following Tdap vaccination.

Ghasri P, Roehmholdt BF, Young LC.

J Drugs Dermatol. 2011 Sep;10(9):1067-9.

PMID:
22052280
48.

Pharmacological actions of the South African medicinal and functional food plant Sceletium tortuosum and its principal alkaloids.

Harvey AL, Young LC, Viljoen AM, Gericke NP.

J Ethnopharmacol. 2011 Oct 11;137(3):1124-9. doi: 10.1016/j.jep.2011.07.035. Epub 2011 Jul 20.

PMID:
21798331
49.

Synthesis of a new series of 1H-imidazol-1-yl substituted 8-phenylxanthines as adenosine receptor ligands.

Bansal R, Kumar G, Gandhi D, Young LC, Harvey AL.

Chem Biodivers. 2011 Jul;8(7):1290-300. doi: 10.1002/cbdv.201000141.

PMID:
21766450
50.

Fusion tyrosine kinase NPM-ALK Deregulates MSH2 and suppresses DNA mismatch repair function novel insights into a potent oncoprotein.

Young LC, Bone KM, Wang P, Wu F, Adam BA, Hegazy S, Gelebart P, Holovati J, Li L, Andrew SE, Lai R.

Am J Pathol. 2011 Jul;179(1):411-21. doi: 10.1016/j.ajpath.2011.03.045. Epub 2011 May 24.

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