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In Vitro Activity of Imipenem/Relebactam and Ceftolozane/Tazobactam against Clinical Isolates of Gram-Negative Bacilli with Difficult-to-Treat Resistance and Multidrug-Resistant Phenotypes - SMART United States 2015-2017.

Karlowsky JA, Lob SH, Raddatz J, DePestel DD, Young K, Motyl MR, Sahm DF.

Clin Infect Dis. 2020 Apr 3. pii: ciaa381. doi: 10.1093/cid/ciaa381. [Epub ahead of print]


Identification of Mosquito Bloodmeals Collected in Diverse Habitats in Malaysian Borneo Using COI Barcoding.

Young KI, Medwid JT, Azar SR, Huff RM, Drumm H, Coffey LL, Pitts RJ, Buenemann M, Vasilakis N, Perera D, Hanley KA.

Trop Med Infect Dis. 2020 Apr 1;5(2). pii: E51. doi: 10.3390/tropicalmed5020051.


Thyrocyte cell survival and adaptation to chronic endoplasmic reticulum stress due to misfolded thyroglobulin.

Morishita Y, Kabil O, Young KZ, Kellogg AP, Chang A, Arvan P.

J Biol Chem. 2020 Apr 2. pii: jbc.RA120.012656. doi: 10.1074/jbc.RA120.012656. [Epub ahead of print]


Draft Genome Sequence of an Adomavirus Associated with Raised Mucoid Skin Lesions on Smallmouth Bass (Micropterus dolomieu).

Iwanowicz LR, Young KT, Adams CR, Blazer VS, Smith GD, Cornman RS.

Microbiol Resour Announc. 2020 Apr 2;9(14). pii: e01479-19. doi: 10.1128/MRA.01479-19.


Truth or Myth: Intraabdominal Pressure Increases in the Lithotomy Position.

Young K, Mou T, Geynisman-Tan J, Tavathia M, Collins S, Mueller M, Lewicky-Gaupp C, Kenton K.

J Minim Invasive Gynecol. 2020 Mar 27. pii: S1553-4650(20)30131-X. doi: 10.1016/j.jmig.2020.03.005. [Epub ahead of print]


Splenic Abscess: Characterizing Management and Outcomes for a Rare Disease.

O'Connor LF, Buonpane CL, Walker CW, Blansfield JA, Widom KA, Torres DM, Wild JL, Young KA.

Am Surg. 2020 Mar 1;86(3):e130-e133. No abstract available.


Paired CT Measures of Emphysema and Small Airways Disease and Lung Function and Exercise Capacity in Smokers with Radiographic Bronchiectasis.

Martinez CH, Okajima Y, Yen A, Maselli DJ, Nardelli P, Rahaghi F, Young K, Kinney G, Hatt C, Galban C, Washko GR, Han M, Estépar RSJ, Diaz AA.

Acad Radiol. 2020 Mar 23. pii: S1076-6332(20)30099-4. doi: 10.1016/j.acra.2020.02.013. [Epub ahead of print]


An optimized procedure for isolation of rodent and human skeletal muscle sarcoplasmic and myofibrillar proteins.

Roberts MD, Young KC, Fox CD, Vann CG, Roberson PA, Osburn SC, Moore JH, Mumford PW, Romero MA, Beck DT, Haun CT, Badisa VLD, Mwashote BM, Ibeanusi V, Kavazis AN.

J Biol Methods. 2020 Feb 24;7(1):e127. doi: 10.14440/jbm.2020.307. eCollection 2020.


How Applicants to General Surgery Residency Define Resilience.

Hayek S, Buonpane C, Hummel C, Lane S, Ellison H, Young K, Shabahang M.

J Surg Educ. 2020 Mar 16. pii: S1931-7204(20)30045-3. doi: 10.1016/j.jsurg.2020.02.011. [Epub ahead of print]


Oligodendrogenesis increases in hippocampal grey and white matter prior to locomotor or memory impairment in an adult mouse model of tauopathy.

Ferreira S, Pitman KA, Summers BS, Wang S, Young KM, Cullen CL.

Eur J Neurosci. 2020 Mar 17. doi: 10.1111/ejn.14726. [Epub ahead of print]


Consensus on the reporting and experimental design of clinical and cognitive-behavioural neurofeedback studies (CRED-nf checklist).

Ros T, Enriquez-Geppert S, Zotev V, Young KD, Wood G, Whitfield-Gabrieli S, Wan F, Vuilleumier P, Vialatte F, Van De Ville D, Todder D, Surmeli T, Sulzer JS, Strehl U, Sterman MB, Steiner NJ, Sorger B, Soekadar SR, Sitaram R, Sherlin LH, Schönenberg M, Scharnowski F, Schabus M, Rubia K, Rosa A, Reiner M, Pineda JA, Paret C, Ossadtchi A, Nicholson AA, Nan W, Minguez J, Micoulaud-Franchi JA, Mehler DMA, Lührs M, Lubar J, Lotte F, Linden DEJ, Lewis-Peacock JA, Lebedev MA, Lanius RA, Kübler A, Kranczioch C, Koush Y, Konicar L, Kohl SH, Kober SE, Klados MA, Jeunet C, Janssen TWP, Huster RJ, Hoedlmoser K, Hirshberg LM, Heunis S, Hendler T, Hampson M, Guggisberg AG, Guggenberger R, Gruzelier JH, Göbel RW, Gninenko N, Gharabaghi A, Frewen P, Fovet T, Fernández T, Escolano C, Ehlis AC, Drechsler R, Christopher deCharms R, Debener S, De Ridder D, Davelaar EJ, Congedo M, Cavazza M, Breteler MHM, Brandeis D, Bodurka J, Birbaumer N, Bazanova OM, Barth B, Bamidis PD, Auer T, Arns M, Thibault RT.

Brain. 2020 Mar 16. pii: awaa009. doi: 10.1093/brain/awaa009. [Epub ahead of print]


Association of Alcohol Screening Scores With Adverse Mental Health Conditions and Substance Use Among US Adults.

Khan MR, Young KE, Caniglia EC, Fiellin DA, Maisto SA, Marshall BDL, Edelman EJ, Gaither JR, Chichetto NE, Tate J, Bryant KJ, Severe M, Stevens ER, Justice A, Braithwaite SR.

JAMA Netw Open. 2020 Mar 2;3(3):e200895. doi: 10.1001/jamanetworkopen.2020.0895.


Multi-omics Analysis of the Intermittent Fasting Response in Mice Identifies an Unexpected Role for HNF4α.

Hatchwell L, Harney DJ, Cielesh M, Young K, Koay YC, O'Sullivan JF, Larance M.

Cell Rep. 2020 Mar 10;30(10):3566-3582.e4. doi: 10.1016/j.celrep.2020.02.051.


Dexamethasone Versus Prednisone for Pediatric Acute Asthma Exacerbations: Specialists' Practice Patterns.

Peterson R, Young KD.

Pediatr Emerg Care. 2020 Mar 6. doi: 10.1097/PEC.0000000000002036. [Epub ahead of print]


Real-time, MinION-based, amplicon sequencing for lineage typing of infectious bronchitis virus from upper respiratory samples.

Butt SL, Erwood EC, Zhang J, Sellers HS, Young K, Lahmers KK, Stanton JB.

J Vet Diagn Invest. 2020 Mar 5:1040638720910107. doi: 10.1177/1040638720910107. [Epub ahead of print]


Snapshot audit of emergency department workplace violence.

Sills RL, Young K, Fatovich DM.

Emerg Med Australas. 2020 Mar 3. doi: 10.1111/1742-6723.13487. [Epub ahead of print] No abstract available.


Genetically Encoded Stealth Nanoparticles of a Zwitterionic Polypeptide-Paclitaxel Conjugate Have a Wider Therapeutic Window than Abraxane in Multiple Tumor Models.

Banskota S, Saha S, Bhattacharya J, Kirmani N, Yousefpour P, Dzuricky M, Zakharov N, Li X, Spasojevic I, Young K, Chilkoti A.

Nano Lett. 2020 Mar 9. doi: 10.1021/acs.nanolett.9b05094. [Epub ahead of print]


Thiol-mediated and catecholamine-enhanced multimerization of a cerebrovascular disease enriched fragment of NOTCH3.

Young KZ, Cartee NMP, Ivanova MI, Wang MM.

Exp Neurol. 2020 Feb 28;328:113261. doi: 10.1016/j.expneurol.2020.113261. [Epub ahead of print]


Treatment of Acute Achilles Tendon Rupture.

Park SH, Lee HS, Young KW, Seo SG.

Clin Orthop Surg. 2020 Mar;12(1):1-8. doi: 10.4055/cios.2020.12.1.1. Epub 2020 Feb 13. Review.


Preliminary Evidence That CD38 Moderates the Association of Neuroticism on Amygdala-Subgenual Cingulate Connectivity.

Tabak BA, Young KS, Torre JB, Way BM, Burklund LJ, Eisenberger NI, Lieberman MD, Craske MG.

Front Neurosci. 2020 Feb 14;14:11. doi: 10.3389/fnins.2020.00011. eCollection 2020.


Identifying duration criteria for eating-disorder remission and recovery through intensive modeling of longitudinal data.

De Young KP, Kambanis PE, Bottera AR, Mancuso C, Thomas JJ, Franko DL, Herzog DB, Walker DC, Anderson D, Eddy KT.

Int J Eat Disord. 2020 Feb 27. doi: 10.1002/eat.23249. [Epub ahead of print]


Childhood Traumatic Experiences and Receptive Anal Intercourse Among Women.

Scheidell JD, Dyer TP, Severe M, Tembunde YE, Young KE, Khan MR.

Perspect Sex Reprod Health. 2020 Mar;52(1):23-30. doi: 10.1363/psrh.12129. Epub 2020 Feb 24.


Decreased cell stiffness enhances leukemia development and progression.

Hu L, Ni F, Wang X, Fay ME, Young KM, Lam WA, Sulchek TA, Qu CK.

Leukemia. 2020 Feb 24. doi: 10.1038/s41375-020-0763-7. [Epub ahead of print] No abstract available.


A Comparison of Treatment Outcomes Between Analysis Populations in the RESTORE-IMI 1 Phase 3 Trial of Imipenem/Cilastatin/Relebactam Versus Colistin Plus Imipenem/Cilastatin in Patients With Imipenem-Nonsusceptible Bacterial Infections.

Kaye KS, Boucher HW, Brown ML, Aggrey A, Khan I, Joeng HK, Tipping RW, Du J, Young K, Butterton JR, Paschke A.

Antimicrob Agents Chemother. 2020 Feb 24. pii: AAC.02203-19. doi: 10.1128/AAC.02203-19. [Epub ahead of print]


Identification of a nanostring signature that differentiates early pancreatic cancers according to stromal composition and predicts clinical outcome.

Sclafani F, Cascione L, Cunningham D, Young K, Carotenuto P, Fassan M, Salati M, Lanese A, Berenguer Pina J, Kouvelakis K, Vendrell I, Said-Huntingford I, Previdi M, Begum R, Gillbanks A, Hedayat S, Sadanandam A, Lampis A, Hahne J, Valeri N, Chau I, Braconi C.

Ann Oncol. 2019 Jul;30 Suppl 4:iv110-iv111. doi: 10.1093/annonc/mdz156.002. Epub 2019 Dec 4. No abstract available.


The use of first, second and beyond line chemotherapy for metastatic pancreatic ductal adenocarcinoma at the Royal Marsden Hospital.

Butters O, Swann F, Leslie I, Young K, Kouvelakis K, Watkins D, Rao S, Chau I, Cunningham D, Starling N.

Ann Oncol. 2019 Jul;30 Suppl 4:iv108. doi: 10.1093/annonc/mdz155.397. Epub 2019 Dec 4. No abstract available.


Effects of Klotho supplementation on hyperoxia-induced renal injury in a rodent model of postnatal nephrogenesis.

Ali MF, Venkatarayappa SKB, Benny M, Rojas C, Yousefi K, Shehadeh LA, Kulandavelu S, Sharma M, Da Silva N, Freundlich M, Abitbol CL, DeFreitas MJ, Young KC.

Pediatr Res. 2020 Feb 14. doi: 10.1038/s41390-020-0803-z. [Epub ahead of print]


UV nail lamps, is there a malignancy risk? A review of the literature.

Khoury A, Young K, O'Neill J.

J Plast Reconstr Aesthet Surg. 2020 Jan 22. pii: S1748-6815(20)30042-5. doi: 10.1016/j.bjps.2020.01.022. [Epub ahead of print] No abstract available.


Human Tyrosinase: Temperature-Dependent Kinetics of Oxidase Activity.

Young KL II, Kassouf C, Dolinska MB, Anderson DE, Sergeev YV.

Int J Mol Sci. 2020 Jan 30;21(3). pii: E895. doi: 10.3390/ijms21030895.


Aging-associated decrease in the histone acetyltransferase KAT6B is linked to altered hematopoietic stem cell differentiation.

Khokhar ES, Borikar S, Eudy E, Stearns T, Young K, Trowbridge JJ.

Exp Hematol. 2020 Feb;82:43-52.e4. doi: 10.1016/j.exphem.2020.01.014. Epub 2020 Feb 1.


Neurologic outcomes of the premature lamb in an extrauterine environment for neonatal development.

McGovern PE, Hornick MA, Mejaddam AY, Lawrence K, Schupper AJ, Rossidis AC, Baumgarten H, Vossough A, Didier RA, Kim A, Partridge EA, Hwang G, Young K, Peranteau WH, Davey MG, Flake AW.

J Pediatr Surg. 2020 Jan 8. pii: S0022-3468(19)30936-4. doi: 10.1016/j.jpedsurg.2019.12.026. [Epub ahead of print]


In vitro activity of imipenem-relebactam against resistant phenotypes of Enterobacteriaceae and Pseudomonas aeruginosa isolated from intraabdominal and urinary tract infection samples - SMART Surveillance Europe 2015-2017.

Lob SH, Karlowsky JA, Young K, Motyl MR, Hawser S, Kothari ND, Sahm DF.

J Med Microbiol. 2020 Feb;69(2):207-217. doi: 10.1099/jmm.0.001142. Epub 2020 Jan 22.


Correction to: C3aR signaling and gliosis in response to neurodevelopmental damage in the cerebellum.

Young KG, Yan K, Picketts DJ.

J Neuroinflammation. 2020 Jan 23;17(1):32. doi: 10.1186/s12974-019-1642-x.


In vitro activity of ceftolozane/tazobactam against phenotypically defined extended-spectrum β-lactamase (ESBL)-positive isolates of Escherichia coli and Klebsiella pneumoniae isolated from hospitalized patients (SMART 2016).

Karlowsky JA, Kazmierczak KM, Young K, Motyl MR, Sahm DF.

Diagn Microbiol Infect Dis. 2020 Apr;96(4):114925. doi: 10.1016/j.diagmicrobio.2019.114925. Epub 2019 Nov 15.


Telemedicine for Pediatric Urologic Postoperative Care is Safe, Convenient and Economical.

Finkelstein JB, Cahill D, Young K, Humphrey K, Campbell J, Schumann C, Nelson CP, Gupta A, Estrada CR Jr.

J Urol. 2020 Jan 17:101097JU0000000000000750. doi: 10.1097/JU.0000000000000750. [Epub ahead of print]


Protein Stability and Functional Characterization of Intra-Melanosomal Domain of Human Recombinant Tyrosinase-Related Protein 1.

Dolinska MB, Young KL 2nd, Kassouf C, Dimitriadis EK, Wingfield PT, Sergeev YV.

Int J Mol Sci. 2020 Jan 3;21(1). pii: E331. doi: 10.3390/ijms21010331.


Mobile Health Technology Interventions for Suicide Prevention: Systematic Review.

Melia R, Francis K, Hickey E, Bogue J, Duggan J, O'Sullivan M, Young K.

JMIR Mhealth Uhealth. 2020 Jan 15;8(1):e12516. doi: 10.2196/12516. Review.


Skeletal Muscle Myofibrillar Protein Abundance Is Higher in Resistance-Trained Men, and Aging in the Absence of Training May Have an Opposite Effect.

Vann CG, Roberson PA, Osburn SC, Mumford PW, Romero MA, Fox CD, Moore JH, Haun CT, Beck DT, Moon JR, Kavazis AN, Young KC, Badisa VLD, Mwashote BM, Ibeanusi V, Singh RK, Roberts MD.

Sports (Basel). 2020 Jan 10;8(1). pii: E7. doi: 10.3390/sports8010007.


Cost-effectiveness analysis of nivolumab for the treatment of squamous cell carcinoma of the head and neck in the United States.

Haddad R, Cohen EEW, Venkatachalam M, Young K, Singh P, Shaw JW, Korytowsky B, Abraham P, Harrington KJ.

J Med Econ. 2020 Jan 29:1-6. doi: 10.1080/13696998.2020.1715414. [Epub ahead of print]


Neonatal hyperoxia exposure induces aortic biomechanical alterations and cardiac dysfunction in juvenile rats.

Benny M, Hernandez DR, Sharma M, Yousefi K, Kulandavelu S, Batlahally S, Zambrano R, Chen P, Martinez EC, Schmidt AF, Shehadeh LA, Vasquez-Padron RI, Wu S, Velazquez OC, Young KC.

Physiol Rep. 2020 Jan;8(1):e14334. doi: 10.14814/phy2.14334.


A case-based approach to integrative medicine for cardiovascular disease prevention.

Slostad B, Khalsa T, Young K, Guerra H, Bhagra A.

J Integr Med. 2020 Mar;18(2):159-162. doi: 10.1016/j.joim.2019.12.001. Epub 2019 Dec 14.


Occupational barriers to accessing and adhering to antiretroviral therapy for female sex workers living with HIV in South Africa.

Parmley LE, Comins CA, Young K, Mcingana M, Phetlhu DR, Guddera V, Mkhize H, Hausler H, Baral S, Schwartz S.

Occup Environ Med. 2020 Feb;77(2):100-106. doi: 10.1136/oemed-2019-105947. Epub 2020 Jan 7.


Operative Results of Plantar Plating for Fifth Metatarsal Stress Fracture.

Young KW, Kim JS, Lee HS, Jegal H, Park YU, Lee KT.

Foot Ankle Int. 2020 Jan 6:1071100719895273. doi: 10.1177/1071100719895273. [Epub ahead of print]


NOTCH3 is non-enzymatically fragmented in inherited cerebral small-vessel disease.

Young KZ, Lee SJ, Zhang X, Cartee NMP, Torres M, Keep SG, Gabbireddy SR, Fontana JL, Qi L, Wang MM.

J Biol Chem. 2020 Feb 14;295(7):1960-1972. doi: 10.1074/jbc.RA119.007724. Epub 2020 Jan 4.


International evaluation of an AI system for breast cancer screening.

McKinney SM, Sieniek M, Godbole V, Godwin J, Antropova N, Ashrafian H, Back T, Chesus M, Corrado GC, Darzi A, Etemadi M, Garcia-Vicente F, Gilbert FJ, Halling-Brown M, Hassabis D, Jansen S, Karthikesalingam A, Kelly CJ, King D, Ledsam JR, Melnick D, Mostofi H, Peng L, Reicher JJ, Romera-Paredes B, Sidebottom R, Suleyman M, Tse D, Young KC, De Fauw J, Shetty S.

Nature. 2020 Jan;577(7788):89-94. doi: 10.1038/s41586-019-1799-6. Epub 2020 Jan 1.


Cross-talk between Myc and p53 in B-cell lymphomas.

Yu L, Yu TT, Young KH.

Chronic Dis Transl Med. 2019 Oct 22;5(3):139-154. doi: 10.1016/j.cdtm.2019.08.001. eCollection 2019 Sep.


Machine Learning Characterization of COPD Subtypes: Insights From the COPDGene Study.

Castaldi PJ, Boueiz A, Yun J, Estepar RSJ, Ross JC, Washko G, Cho MH, Hersh CP, Kinney GL, Young KA, Regan EA, Lynch DA, Criner GJ, Dy JG, Rennard SI, Casaburi R, Make BJ, Crapo J, Silverman EK, Hokanson JE; COPDGene Investigators.

Chest. 2019 Dec 28. pii: S0012-3692(19)34456-3. doi: 10.1016/j.chest.2019.11.039. [Epub ahead of print] Review.


Zoonotic Babesia: A scoping review of the global evidence.

Young KM, Corrin T, Wilhelm B, Uhland C, Greig J, Mascarenhas M, Waddell LA.

PLoS One. 2019 Dec 30;14(12):e0226781. doi: 10.1371/journal.pone.0226781. eCollection 2019.


A Tale of Specialization in 2 Professions: Comparing the Development of Radiology in Chiropractic and Medicine.

Young KJ.

J Chiropr Humanit. 2019 Dec 10;26:3-18. doi: 10.1016/j.echu.2019.09.001. eCollection 2019 Dec.


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