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Multi-omics: Differential expression of IFN-γ results in distinctive mechanistic features linking chronic inflammation, gut dysbiosis, and autoimmune diseases.

Bae HR, Leung PSC, Hodge DL, Fenimore JM, Jeon SM, Thovarai V, Dzutsev A, Welcher AA, Boedigheimer M, Damore MA, Choi MS, Fravell RA, Trinchieri G, Gershwin ME, Young HA.

J Autoimmun. 2020 Mar 24:102436. doi: 10.1016/j.jaut.2020.102436. [Epub ahead of print]


Ketoxime peptide ligations: oxidative couplings of alkoxyamines to N-aryl peptides.

Guthrie QAE, Young HA, Proulx C.

Chem Sci. 2019 Aug 29;10(41):9506-9512. doi: 10.1039/c9sc04028e. eCollection 2019 Nov 7.


Clinical Guidance for Point-of-Care Ultrasound in the Emergency and Critical Care Areas after Implementing Insurance Coverage in Korea.

Choi WJ, Ha YR, Oh JH, Cho YS, Lee WW, Sohn YD, Cho GC, Koh CY, Do HH, Jeong WJ, Ryoo SM, Kwon JH, Kim HM, Kim SJ, Park CY, Lee JH, Lee JH, Lee DH, Park SY, Kang BS.

J Korean Med Sci. 2020 Feb 24;35(7):e54. doi: 10.3346/jkms.2020.35.e54. Review.


Impact of difficult-to-treat resistance in gram-negative bacteremia on mortality: retrospective analysis of nationwide surveillance data.

Huh K, Chung DR, Ha YE, Ko JH, Kim SH, Kim MJ, Huh HJ, Lee NY, Cho SY, Kang CI, Peck KR, Song JH; Korean Antimicrobial Resistance Surveillance Network (KARS-Net) investigators.

Clin Infect Dis. 2020 Jan 29. pii: ciaa084. doi: 10.1093/cid/ciaa084. [Epub ahead of print]


N-Arylation of Amino Acid Esters to Expand Side Chain Diversity in Ketoxime Peptide Ligations.

Young HA, Guthrie QAE, Proulx C.

J Org Chem. 2020 Feb 7;85(3):1748-1755. doi: 10.1021/acs.joc.9b02810. Epub 2019 Dec 17.


Autonomic adaptations mediate the effect of hydration on brain functioning and mood: Evidence from two randomized controlled trials.

Young HA, Cousins A, Johnston S, Fletcher JM, Benton D.

Sci Rep. 2019 Nov 11;9(1):16412. doi: 10.1038/s41598-019-52775-5.


Adaptive in vivo device for theranostics of inflammation: Real-time monitoring of interferon-γ and aspirin.

Cao C, Jin R, Wei H, Liu Z, Ni S, Liu GJ, Young HA, Chen X, Liu G.

Acta Biomater. 2020 Jan 1;101:372-383. doi: 10.1016/j.actbio.2019.10.021. Epub 2019 Oct 15.


Water: The Cinderella Nutrient.

Benton D, Young HA.

J Nutr. 2019 Dec 1;149(12):2081-2082. doi: 10.1093/jn/nxz226. No abstract available.


Role of fruit juice in achieving the 5-a-day recommendation for fruit and vegetable intake.

Benton D, Young HA.

Nutr Rev. 2019 Sep 4. pii: nuz031. doi: 10.1093/nutrit/nuz031. [Epub ahead of print] Erratum in: Nutr Rev. 2020 Mar 1;78(3):260.


Approach for naso-orbito-ethmoidal fracture.

Ha YI, Kim SH, Park ES, Kim YB.

Arch Craniofac Surg. 2019 Aug;20(4):219-222. doi: 10.7181/acfs.2019.00255. Epub 2019 Aug 20.


The Effect of Hypo-Hydration on Mood and Cognition Is Influenced by Electrolyte in a Drink and Its Colour: A Randomised Trial.

Cousins AL, Young HA, Thomas AG, Benton D.

Nutrients. 2019 Aug 24;11(9). pii: E2002. doi: 10.3390/nu11092002.


Sugary drinks and cancer risk: more to diet than just sugar.

Benton D, Young HA.

BMJ. 2019 Aug 12;366:l5095. doi: 10.1136/bmj.l5095. No abstract available.


Value of Additional Ultrasound Examination in Patients with Equivocal Computed Tomography Findings of Acute Appendicitis: Comparison with Computed Tomography Reassessment.

Sim JY, Kim HJ, Jang SK, Yeon JW, Jeon BG, Ha YR, Paik SY, Cho JS.

J Med Ultrasound. 2019 Apr-Jun;27(2):75-80. doi: 10.4103/JMU.JMU_52_18. Epub 2019 May 7.


Pesticide interactions and risks of sperm chromosomal abnormalities.

Figueroa ZI, Young HA, Mumford SL, Meeker JD, Barr DB, Gray GM, Perry MJ.

Int J Hyg Environ Health. 2019 Aug;222(7):1021-1029. doi: 10.1016/j.ijheh.2019.07.001. Epub 2019 Jul 13.


IFN-γ: A cytokine at the right time, is in the right place.

Burke JD, Young HA.

Semin Immunol. 2019 Jun;43:101280. doi: 10.1016/j.smim.2019.05.002. Epub 2019 Jun 17. Review.


Ion Gresser 1928-2019.

Vilcek J, Young HA.

Nat Immunol. 2019 Jul;20(7):775. doi: 10.1038/s41590-019-0428-8. No abstract available.


Durvalumab in Combination with Olaparib in Patients with Relapsed SCLC: Results from a Phase II Study.

Thomas A, Vilimas R, Trindade C, Erwin-Cohen R, Roper N, Xi L, Krishnasamy V, Levy E, Mammen A, Nichols S, Chen Y, Velcheti V, Yin F, Szabo E, Pommier Y, Steinberg SM, Trepel JB, Raffeld M, Young HA, Khan J, Hewitt S, Lee JM.

J Thorac Oncol. 2019 Aug;14(8):1447-1457. doi: 10.1016/j.jtho.2019.04.026. Epub 2019 May 4.


Meeting Overview: Interferon Lambda-Disease Impact and Therapeutic Potential.

O'Brien TR, Young HA, Donnelly RP, Prokunina-Olsson L.

J Interferon Cytokine Res. 2019 Oct;39(10):586-591. doi: 10.1089/jir.2019.0018. Epub 2019 Apr 17.


Report on the 2018 Cancer, Autoimmunity, and Immunology Conference.

Curran CS, Sommers CL, Young HA, Bourcier K, Mancini M, Sharon E.

J Immunol. 2019 May 15;202(10):2823-2828. doi: 10.4049/jimmunol.1900264. Epub 2019 Apr 15.


Interoceptive accuracy moderates the response to a glucose load: a test of the predictive coding framework.

Young HA, Gaylor CM, de Kerckhove D, Watkins H, Benton D.

Proc Biol Sci. 2019 Mar 13;286(1898):20190244. doi: 10.1098/rspb.2019.0244.


Critical role of post-transcriptional regulation for IFN-γ in tumor-infiltrating T cells.

Salerno F, Guislain A, Freen-Van Heeren JJ, Nicolet BP, Young HA, Wolkers MC.

Oncoimmunology. 2018 Oct 22;8(2):e1532762. doi: 10.1080/2162402X.2018.1532762. eCollection 2019.


Dynamics of alveolar bone healing after the removal of orthodontic temporary anchorage devices.

Kim SJ, Ha YD, Kim E, Jang W, Hwang S, Nguyen T, Ko CC, Choi YJ, Kim KH, Chung CJ.

J Periodontal Res. 2019 Aug;54(4):388-395. doi: 10.1111/jre.12640. Epub 2019 Jan 24.


WITHDRAWN: HM47118A, a novel insulinotropic GPR119 agonist and potential oral antidiabetic agent.

Song TH, Lee SD, Ha YE, Choi KJ, Lee SH, Kim YH, Suh KH, Chun YJ.

Diabetes Res Clin Pract. 2019 Jan 11. pii: S0168-8227(18)31385-8. doi: 10.1016/j.diabres.2019.01.011. [Epub ahead of print]


Partners in Crime: Fledgling Tumors Hijack Inflammation.

Kuppusamy B, Young HA.

J Interferon Cytokine Res. 2019 Jan;39(1):1-5. doi: 10.1089/jir.2018.29011.bku. No abstract available.


Mediation of the association of smoking and microvascular complications by glycemic control in type 1 diabetes.

Braffett BH, Rice MM, Young HA, Lachin JM.

PLoS One. 2019 Jan 7;14(1):e0210367. doi: 10.1371/journal.pone.0210367. eCollection 2019.


Thymic expression of IL-4 and IL-15 after systemic inflammatory or infectious Th1 disease processes induce the acquisition of "innate" characteristics during CD8+ T cell development.

Baez NS, Cerbán F, Savid-Frontera C, Hodge DL, Tosello J, Acosta-Rodriguez E, Almada L, Gruppi A, Viano ME, Young HA, Rodriguez-Galan MC.

PLoS Pathog. 2019 Jan 4;15(1):e1007456. doi: 10.1371/journal.ppat.1007456. eCollection 2019 Jan.


Failure of Ciprofloxacin Therapy in the Treatment of Community-Acquired Acute Pyelonephritis caused by In-Vitro Susceptible Escherichia coli Strain Producing CTX-Type Extended-Spectrum β-Lactamase.

Seok H, Cha MK, Kang CI, Cho SY, Kim SH, Ha YE, Chung DR, Peck KR, Song JH.

Infect Chemother. 2018 Dec;50(4):357-361. doi: 10.3947/ic.2018.50.4.357.


DDS promotes longevity through a microbiome-mediated starvation signal.

Choi H, Cho SC, Ha YW, Ocampo B, Park S, Chen S, Bennett CF, Han J, Rossner R, Kang JS, Lee YL, Park SC, Kaeberlein M.

Transl Med Aging. 2019;3:64-69. doi: 10.1016/j.tma.2019.07.001. Epub 2019 Jul 3.


Therapeutic and immunological interventions in primary biliary cholangitis: from mouse models to humans.

Tanaka A, Leung PSC, Young HA, Gershwin ME.

Arch Med Sci. 2018 Jun;14(4):930-940. doi: 10.5114/aoms.2017.70995. Epub 2017 Oct 24. No abstract available.


Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells.

Salerno F, Engels S, van den Biggelaar M, van Alphen FPJ, Guislain A, Zhao W, Hodge DL, Bell SE, Medema JP, von Lindern M, Turner M, Young HA, Wolkers MC.

Nat Immunol. 2018 Aug;19(8):828-837. doi: 10.1038/s41590-018-0155-6. Epub 2018 Jul 9.


Impact of high MIC of fluconazole on outcomes of Candida glabrata bloodstream infection: a retrospective multicenter cohort study.

Ko JH, Peck KR, Jung DS, Lee JY, Kim HA, Ryu SY, Jung SI, Joo EJ, Cheon S, Kim YS, Kim SW, Cho SY, Ha YE, Kang CI, Chung DR, Lee NY, Song JH.

Diagn Microbiol Infect Dis. 2018 Oct;92(2):127-132. doi: 10.1016/j.diagmicrobio.2018.05.001. Epub 2018 Jun 19.


Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience.

Ko JH, Seok H, Cho SY, Ha YE, Baek JY, Kim SH, Kim YJ, Park JK, Chung CR, Kang ES, Cho D, Müller MA, Drosten C, Kang CI, Chung DR, Song JH, Peck KR.

Antivir Ther. 2018;23(7):617-622. doi: 10.3851/IMP3243. Epub 2018 Jun 20.


Factors affecting the public awareness and behavior on antibiotic use.

Huh K, Chung DR, Kim SH, Cho SY, Ha YE, Kang CI, Peck KR, Song JH.

Eur J Clin Microbiol Infect Dis. 2018 Aug;37(8):1547-1552. doi: 10.1007/s10096-018-3283-x. Epub 2018 May 18.


Interferon-Gamma Impairs Maintenance and Alters Hematopoietic Support of Bone Marrow Mesenchymal Stromal Cells.

Goedhart M, Cornelissen AS, Kuijk C, Geerman S, Kleijer M, van Buul JD, Huveneers S, Raaijmakers MHGP, Young HA, Wolkers MC, Voermans C, Nolte MA.

Stem Cells Dev. 2018 May 1;27(9):579-589. doi: 10.1089/scd.2017.0196. Epub 2018 Apr 16.


Risk Factors for Community-Onset Pneumonia Caused by Levofloxacin-Nonsusceptible Streptococcus pneumoniae.

Seok H, Kang CI, Huh K, Cho SY, Ha YE, Chung DR, Peck KR.

Microb Drug Resist. 2018 Nov;24(9):1412-1416. doi: 10.1089/mdr.2017.0416. Epub 2018 Mar 22.


Heart-rate variability: a biomarker to study the influence of nutrition on physiological and psychological health?

Young HA, Benton D.

Behav Pharmacol. 2018 Apr;29(2 and 3-Spec Issue):140-151. doi: 10.1097/FBP.0000000000000383. Review.


Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions.

Menk AV, Scharping NE, Moreci RS, Zeng X, Guy C, Salvatore S, Bae H, Xie J, Young HA, Wendell SG, Delgoffe GM.

Cell Rep. 2018 Feb 6;22(6):1509-1521. doi: 10.1016/j.celrep.2018.01.040.


Host susceptibility to MERS-CoV infection, a retrospective cohort study of the 2015 Korean MERS outbreak.

Ko JH, Seok H, Park GE, Lee JY, Lee JY, Cho SY, Ha YE, Kang JM, Kim YJ, Kang CI, Chung DR, Song JH, Peck KR.

J Infect Chemother. 2018 Feb;24(2):150-152. doi: 10.1016/j.jiac.2017.09.008. Epub 2017 Dec 6.


Thio-barbiturate-derived compounds are novel antioxidants to prevent LPS-induced inflammation in the liver.

Moon KM, Lee B, Jeong JW, Kim DH, Park YJ, Kim HR, Park JY, Kim MJ, An HJ, Lee EK, Ha YM, Im E, Chun P, Ma JY, Cho WK, Moon HR, Chung HY.

Oncotarget. 2017 Oct 10;8(53):91662-91673. doi: 10.18632/oncotarget.21714. eCollection 2017 Oct 31.


Clinical predictors of Stenotrophomonas maltophilia bacteremia in adult patients with hematologic malignancy.

Kim SH, Cho SY, Kang CI, Seok H, Huh K, Ha YE, Chung DR, Lee NY, Peck KR, Song JH.

Ann Hematol. 2018 Feb;97(2):343-350. doi: 10.1007/s00277-017-3178-4. Epub 2017 Nov 14.


Toward solving the etiological mystery of primary biliary cholangitis.

Tanakaa A, Leung PS, Young HA, Gershwin ME.

Hepatol Commun. 2017 Jun;1(4):275-287. doi: 10.1002/hep4.1044. Epub 2017 May 18.


Can clinical scoring systems improve the diagnostic accuracy in patients with suspected adult appendicitis and equivocal preoperative computed tomography findings?

Chae MS, Hong CK, Ha YR, Chae MK, Kim YS, Shin TY, Ahn JH.

Clin Exp Emerg Med. 2017 Oct 20;4(4):214-221. doi: 10.15441/ceem.16.168. eCollection 2017 Dec.


Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: A case report.

Ha YW, Kim CH, Park Y, Sohn JW, Kim MJ, Yoon YK.

Medicine (Baltimore). 2017 Oct;96(42):e8323. doi: 10.1097/MD.0000000000008323.


Getting to the heart of the matter: Does aberrant interoceptive processing contribute towards emotional eating?

Young HA, Williams C, Pink AE, Freegard G, Owens A, Benton D.

PLoS One. 2017 Oct 18;12(10):e0186312. doi: 10.1371/journal.pone.0186312. eCollection 2017.


Superb feeding behavior of Aedes albopictus transmitting Zika virus.

Ha YR, Kim JH, Ryu J, Lee SJ.

PLoS One. 2017 Sep 28;12(9):e0184871. doi: 10.1371/journal.pone.0184871. eCollection 2017.


Mycobacterium abscessus glossitis.

Ko JH, Kang CI, Cho SY, Ha YE, Lee NY, Kim SJ, Chung DR, Peck KR, Song JH.

Lancet Infect Dis. 2017 Oct;17(10):1098. doi: 10.1016/S1473-3099(17)30525-X. No abstract available.


The interplay of type I and type II interferons in murine autoimmune cholangitis as a basis for sex-biased autoimmunity.

Bae HR, Hodge DL, Yang GX, Leung PSC, Chodisetti SB, Valencia JC, Sanford M, Fenimore JM, Rahman ZSM, Tsuneyama K, Norman GL, Gershwin ME, Young HA.

Hepatology. 2018 Apr;67(4):1408-1419. doi: 10.1002/hep.29524. Epub 2018 Feb 18.


Discrepant susceptibility to gentamicin despite amikacin resistance in Klebsiella pneumoniae by VITEK 2 represents false susceptibility associated with the armA 16S rRNA methylase gene.

Ko JH, Baek JY, Peck KR, Cho SY, Ha YE, Kim SH, Huh HJ, Lee NY, Kang CI, Chung DR, Song JH.

J Med Microbiol. 2017 Oct;66(10):1448-1450. doi: 10.1099/jmm.0.000583. Epub 2017 Sep 12.


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