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The Capacity of the Fecal Microbiota From Malawian Infants to Ferment Resistant Starch.

Wang Y, Mortimer EK, Katundu KGH, Kalanga N, Leong LEX, Gopalsamy GL, Christophersen CT, Richard AC, Shivasami A, Abell GCJ, Young GP, Rogers GB.

Front Microbiol. 2019 Jun 26;10:1459. doi: 10.3389/fmicb.2019.01459. eCollection 2019.


A Randomized Controlled Trial Testing Provision of Fecal and Blood Test Options on Participation for Colorectal Cancer Screening.

Symonds EL, Hughes D, Flight I, Woodman R, Chen G, Ratcliffe J, Pedersen SK, Fraser RJL, Wilson CJ, Young GP.

Cancer Prev Res (Phila). 2019 Sep;12(9):631-640. doi: 10.1158/1940-6207.CAPR-19-0089. Epub 2019 Jul 2.


Resistant Starch is Actively Fermented by Infant Faecal Microbiota and Increases Microbial Diversity.

Gopalsamy G, Mortimer E, Greenfield P, Bird AR, Young GP, Christophersen CT.

Nutrients. 2019 Jun 14;11(6). pii: E1345. doi: 10.3390/nu11061345.


Low Sensitivity of Fecal Immunochemical Tests and Blood-Based Markers of DNA Hypermethylation for Detection of Sessile Serrated Adenomas/Polyps.

Cock C, Anwar S, Byrne SE, Meng R, Pedersen S, Fraser RJL, Young GP, Symonds EL.

Dig Dis Sci. 2019 Sep;64(9):2555-2562. doi: 10.1007/s10620-019-05569-8. Epub 2019 Mar 5.


Reducing the number of surveillance colonoscopies with faecal immunochemical tests.

Symonds EL, Cornthwaite K, Fraser RJL, Bampton P, Cock C, Young GP.

Gut. 2019 Feb 26. pii: gutjnl-2019-318370. doi: 10.1136/gutjnl-2019-318370. [Epub ahead of print] No abstract available.


The Global Paradigm Shift in Screening for Colorectal Cancer.

Young GP, Rabeneck L, Winawer SJ.

Gastroenterology. 2019 Mar;156(4):843-851.e2. doi: 10.1053/j.gastro.2019.02.006. Epub 2019 Feb 16. No abstract available.


The significance of the small adenoma: a longitudinal study of surveillance colonoscopy in an Australian population.

Symonds EL, Cole SR, Lau SY, Steele S, Meng R, Woodman RJ, Young GP, Cock C, Fraser R, Bampton P.

Eur J Gastroenterol Hepatol. 2019 May;31(5):563-569. doi: 10.1097/MEG.0000000000001358.


The impact of sample type and procedural attributes on relative acceptability of different colorectal cancer screening regimens.

Osborne JM, Flight I, Wilson CJ, Chen G, Ratcliffe J, Young GP.

Patient Prefer Adherence. 2018 Sep 18;12:1825-1836. doi: 10.2147/PPA.S172143. eCollection 2018.


Comparison of a sports-hydration drink containing high amylose starch with usual hydration practice in Australian rules footballers during intense summer training.

O'Connell SM, Woodman RJ, Brown IL, Vincent DJ, Binder HJ, Ramakrishna BS, Young GP.

J Int Soc Sports Nutr. 2018 Sep 21;15(1):46. doi: 10.1186/s12970-018-0253-8.


Effects of Dietary Fibre from the Traditional Indonesian Food, Green Cincau (Premna oblongifolia Merr.) on Preneoplastic Lesions and Short Chain Fatty Acid Production in an Azoxymethane Rat Model of Colon Cancer.

Nurdin SU, Le Leu RK, Aburto-Medina A, Young GP, Stangoulis JCR, Ball AS, Abbott CA.

Int J Mol Sci. 2018 Aug 31;19(9). pii: E2593. doi: 10.3390/ijms19092593.


The Use of Circulating Tumor DNA for Prognosis of Gastrointestinal Cancers.

Saluja H, Karapetis CS, Pedersen SK, Young GP, Symonds EL.

Front Oncol. 2018 Jul 24;8:275. doi: 10.3389/fonc.2018.00275. eCollection 2018. Review.


Relationship between post-surgery detection of methylated circulating tumor DNA with risk of residual disease and recurrence-free survival.

Murray DH, Symonds EL, Young GP, Byrne S, Rabbitt P, Roy A, Cornthwaite K, Karapetis CS, Pedersen SK.

J Cancer Res Clin Oncol. 2018 Sep;144(9):1741-1750. doi: 10.1007/s00432-018-2701-x. Epub 2018 Jul 10.


World Endoscopy Organization Consensus Statements on Post-Colonoscopy and Post-Imaging Colorectal Cancer.

Rutter MD, Beintaris I, Valori R, Chiu HM, Corley DA, Cuatrecasas M, Dekker E, Forsberg A, Gore-Booth J, Haug U, Kaminski MF, Matsuda T, Meijer GA, Morris E, Plumb AA, Rabeneck L, Robertson DJ, Schoen RE, Singh H, Tinmouth J, Young GP, Sanduleanu S.

Gastroenterology. 2018 Sep;155(3):909-925.e3. doi: 10.1053/j.gastro.2018.05.038. Epub 2018 Jun 27.


Circulating tumour DNA for monitoring colorectal cancer-a prospective cohort study to assess relationship to tissue methylation, cancer characteristics and surgical resection.

Symonds EL, Pedersen SK, Murray DH, Jedi M, Byrne SE, Rabbitt P, Baker RT, Bastin D, Young GP.

Clin Epigenetics. 2018 May 16;10:63. doi: 10.1186/s13148-018-0500-5. eCollection 2018.


Methylation and Gene Expression of BCAT1 and IKZF1 in Colorectal Cancer Tissues.

Jedi M, Young GP, Pedersen SK, Symonds EL.

Clin Med Insights Oncol. 2018 May 10;12:1179554918775064. doi: 10.1177/1179554918775064. eCollection 2018.


Early-Life Antibiotic-Driven Dysbiosis Leads to Dysregulated Vaccine Immune Responses in Mice.

Lynn MA, Tumes DJ, Choo JM, Sribnaia A, Blake SJ, Leong LEX, Young GP, Marshall HS, Wesselingh SL, Rogers GB, Lynn DJ.

Cell Host Microbe. 2018 May 9;23(5):653-660.e5. doi: 10.1016/j.chom.2018.04.009.


Demand for Colonoscopy in Colorectal Cancer Screening Using a Quantitative Fecal Immunochemical Test and Age/Sex-Specific Thresholds for Test Positivity.

Chen SL, Hsu CY, Yen AM, Young GP, Chiu SY, Fann JC, Lee YC, Chiu HM, Chiou ST, Chen HH.

Cancer Epidemiol Biomarkers Prev. 2018 Jun;27(6):704-709. doi: 10.1158/1055-9965.EPI-17-0387. Epub 2018 Mar 28.


Web-Based Communication Strategies Designed to Improve Intention to Minimize Risk for Colorectal Cancer: Randomized Controlled Trial.

Wilson C, Flight I, Zajac IT, Turnbull D, Young GP, Olver I.

JMIR Cancer. 2018 Feb 12;4(1):e2. doi: 10.2196/cancer.8250.


Patterns of participation over four rounds of annual fecal immunochemical test-based screening for colorectal cancer: what predicts rescreening?

Osborne JM, Wilson C, Duncan A, Cole SR, Flight I, Turnbull D, Hughes DL, Young GP.

BMC Public Health. 2017 Aug 1;18(1):81. doi: 10.1186/s12889-017-4634-8. Erratum in: BMC Public Health. 2017 Sep 22;17 (1):736.


Findings in young adults at colonoscopy from a hospital service database audit.

Wong S, Lidums I, Rosty C, Ruszkiewicz A, Parry S, Win AK, Tomita Y, Vatandoust S, Townsend A, Patel D, Hardingham JE, Roder D, Smith E, Drew P, Marker J, Uylaki W, Hewett P, Worthley DL, Symonds E, Young GP, Price TJ, Young JP.

BMC Gastroenterol. 2017 Apr 19;17(1):56. doi: 10.1186/s12876-017-0612-y.


Drug-development concepts as guides for optimizing clinical trials of supplemental zinc for populations at risk of deficiency or diarrhea.

Alpers DH, Young GP, Tran CD, Mortimer EK, Gopalsamy GL, Krebs NF, Manary MJ, Ramakrishna BS, Binder HJ, Brown IL, Miller LV.

Nutr Rev. 2017 Mar 1;75(3):147-162. doi: 10.1093/nutrit/nuw065. Review.


Uptake of a colorectal cancer screening blood test in people with elevated risk for cancer who cannot or will not complete a faecal occult blood test.

Symonds EL, Cock C, Meng R, Cole SR, Fraser RJL, Young GP.

Eur J Cancer Prev. 2018 Sep;27(5):425-432. doi: 10.1097/CEJ.0000000000000352.


Effect of sample storage temperature and buffer formulation on faecal immunochemical test haemoglobin measurements.

Symonds EL, Cole SR, Bastin D, Fraser RJ, Young GP.

J Med Screen. 2017 Dec;24(4):176-181. doi: 10.1177/0969141316686808. Epub 2017 Jan 10.


Evaluation of Methylation Biomarkers for Detection of Circulating Tumor DNA and Application to Colorectal Cancer.

Mitchell SM, Ho T, Brown GS, Baker RT, Thomas ML, McEvoy A, Xu ZZ, Ross JP, Lockett TJ, Young GP, LaPointe LC, Pedersen SK, Molloy PL.

Genes (Basel). 2016 Dec 15;7(12). pii: E125.


Supplementation with Brazil nuts and green tea extract regulates targeted biomarkers related to colorectal cancer risk in humans.

Hu Y, McIntosh GH, Le Leu RK, Somashekar R, Meng XQ, Gopalsamy G, Bambaca L, McKinnon RA, Young GP.

Br J Nutr. 2016 Dec;116(11):1901-1911. doi: 10.1017/S0007114516003937. Epub 2016 Dec 7.


A cross-sectional study comparing a blood test for methylated BCAT1 and IKZF1 tumor-derived DNA with CEA for detection of recurrent colorectal cancer.

Young GP, Pedersen SK, Mansfield S, Murray DH, Baker RT, Rabbitt P, Byrne S, Bambacas L, Hollington P, Symonds EL.

Cancer Med. 2016 Oct;5(10):2763-2772. doi: 10.1002/cam4.868. Epub 2016 Oct 11.


Theory-based modifications of an advanced notification letter improves screening for bowel cancer in men: A randomised controlled trial.

Zajac IT, Duncan AC, Flight I, Wittert GA, Cole SR, Young GP, Wilson CJ, Turnbull DA.

Soc Sci Med. 2016 Sep;165:1-9. doi: 10.1016/j.socscimed.2016.06.036. Epub 2016 Jul 1.


Manipulation of the gut microbiota using resistant starch is associated with protection against colitis-associated colorectal cancer in rats.

Hu Y, Le Leu RK, Christophersen CT, Somashekar R, Conlon MA, Meng XQ, Winter JM, Woodman RJ, McKinnon R, Young GP.

Carcinogenesis. 2016 Apr;37(4):366-375. doi: 10.1093/carcin/bgw019. Epub 2016 Feb 19.


Recommendations for a step-wise comparative approach to the evaluation of new screening tests for colorectal cancer.

Young GP, Senore C, Mandel JS, Allison JE, Atkin WS, Benamouzig R, Bossuyt PM, Silva MD, Guittet L, Halloran SP, Haug U, Hoff G, Itzkowitz SH, Leja M, Levin B, Meijer GA, O'Morain CA, Parry S, Rabeneck L, Rozen P, Saito H, Schoen RE, Seaman HE, Steele RJ, Sung JJ, Winawer SJ.

Cancer. 2016 Mar 15;122(6):826-39. doi: 10.1002/cncr.29865. Epub 2016 Feb 1.


Sociodemographic disparities in survival from colorectal cancer in South Australia: a population-wide data linkage study.

Beckmann KR, Bennett A, Young GP, Cole SR, Joshi R, Adams J, Singhal N, Karapetis C, Wattchow D, Roder D.

BMC Health Serv Res. 2016 Jan 20;16:24. doi: 10.1186/s12913-016-1263-3.


A Blood Test for Methylated BCAT1 and IKZF1 vs. a Fecal Immunochemical Test for Detection of Colorectal Neoplasia.

Symonds EL, Pedersen SK, Baker RT, Murray DH, Gaur S, Cole SR, Gopalsamy G, Mangira D, LaPointe LC, Young GP.

Clin Transl Gastroenterol. 2016 Jan 14;7:e137. doi: 10.1038/ctg.2015.67.


Improving Participation in Colorectal Cancer Screening: a Randomised Controlled Trial of Sequential Offers of Faecal then Blood Based Non-Invasive Tests.

Symonds EL, Pedersen S, Cole SR, Massolino J, Byrne D, Guy J, Backhouse P, Fraser RJ, LaPointe L, Young GP.

Asian Pac J Cancer Prev. 2015;16(18):8455-60.


Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia.

Pedersen SK, Symonds EL, Baker RT, Murray DH, McEvoy A, Van Doorn SC, Mundt MW, Cole SR, Gopalsamy G, Mangira D, LaPointe LC, Dekker E, Young GP.

BMC Cancer. 2015 Oct 6;15:654. doi: 10.1186/s12885-015-1674-2.


Gender differences in faecal haemoglobin concentration.

Symonds EL, Osborne J, Cole SR, Bampton P, Fraser R, Young GP.

J Med Screen. 2016 Mar;23(1):54. doi: 10.1177/0969141315597018. Epub 2015 Jul 20. No abstract available.


Butyrylated starch intake can prevent red meat-induced O6-methyl-2-deoxyguanosine adducts in human rectal tissue: a randomised clinical trial.

Le Leu RK, Winter JM, Christophersen CT, Young GP, Humphreys KJ, Hu Y, Gratz SW, Miller RB, Topping DL, Bird AR, Conlon MA.

Br J Nutr. 2015 Jul;114(2):220-30. doi: 10.1017/S0007114515001750. Epub 2015 Jun 17.


Colorectal cancer screening: a global overview of existing programmes.

Schreuders EH, Ruco A, Rabeneck L, Schoen RE, Sung JJ, Young GP, Kuipers EJ.

Gut. 2015 Oct;64(10):1637-49. doi: 10.1136/gutjnl-2014-309086. Epub 2015 Jun 3. Review.


The potential for zinc stable isotope techniques and modelling to determine optimal zinc supplementation.

Tran CD, Gopalsamy GL, Mortimer EK, Young GP.

Nutrients. 2015 May 29;7(6):4271-95. doi: 10.3390/nu7064271. Review.


Role of Red Meat and Resistant Starch in Promutagenic Adduct Formation, MGMT Repair, Thymic Lymphoma and Intestinal Tumourigenesis in Msh2 -Deficient Mice.

Winter JM, Hu Y, Young GP, Kohonen-Corish MR, Le Leu RK.

J Nutrigenet Nutrigenomics. 2014;7(4-6):299-313. doi: 10.1159/000381675. Epub 2015 May 27.


Factors affecting faecal immunochemical test positive rates: demographic, pathological, behavioural and environmental variables.

Symonds EL, Osborne JM, Cole SR, Bampton PA, Fraser RJ, Young GP.

J Med Screen. 2015 Dec;22(4):187-93. doi: 10.1177/0969141315584783. Epub 2015 May 14.


A two-gene blood test for methylated DNA sensitive for colorectal cancer.

Pedersen SK, Baker RT, McEvoy A, Murray DH, Thomas M, Molloy PL, Mitchell S, Lockett T, Young GP, LaPointe LC.

PLoS One. 2015 Apr 30;10(4):e0125041. doi: 10.1371/journal.pone.0125041. eCollection 2015.


A prediction model for colon cancer surveillance data.

Good NM, Suresh K, Young GP, Lockett TJ, Macrae FA, Taylor JM.

Stat Med. 2015 Aug 15;34(18):2662-75. doi: 10.1002/sim.6500. Epub 2015 Apr 6.


Ideal colonoscopic surveillance intervals to reduce incidence of advanced adenoma and colorectal cancer.

Good NM, Macrae FA, Young GP, O'Dywer J, Slattery M, Venables W, Lockett TJ, O'Dwyer M.

J Gastroenterol Hepatol. 2015 Jul;30(7):1147-54. doi: 10.1111/jgh.12904.


The relevance of the colon to zinc nutrition.

Gopalsamy GL, Alpers DH, Binder HJ, Tran CD, Ramakrishna BS, Brown I, Manary M, Mortimer E, Young GP.

Nutrients. 2015 Jan 14;7(1):572-83. doi: 10.3390/nu7010572. Review.


Advances in Fecal Occult Blood Tests: the FIT revolution.

Young GP, Symonds EL, Allison JE, Cole SR, Fraser CG, Halloran SP, Kuipers EJ, Seaman HE.

Dig Dis Sci. 2015 Mar;60(3):609-22. doi: 10.1007/s10620-014-3445-3. Epub 2014 Dec 10. Review.


Rising incidence of early-onset colorectal cancer in Australia over two decades: report and review.

Young JP, Win AK, Rosty C, Flight I, Roder D, Young GP, Frank O, Suthers GK, Hewett PJ, Ruszkiewicz A, Hauben E, Adelstein BA, Parry S, Townsend A, Hardingham JE, Price TJ.

J Gastroenterol Hepatol. 2015 Jan;30(1):6-13. doi: 10.1111/jgh.12792. Review.


Zinc deficiency in children with environmental enteropathy-development of new strategies: report from an expert workshop.

Young GP, Mortimer EK, Gopalsamy GL, Alpers DH, Binder HJ, Manary MJ, Ramakrishna BS, Brown IL, Brewer TG.

Am J Clin Nutr. 2014 Oct;100(4):1198-207. doi: 10.3945/ajcn.113.075036. Epub 2014 Aug 13.


Definition and taxonomy of interval colorectal cancers: a proposal for standardising nomenclature.

Sanduleanu S, le Clercq CM, Dekker E, Meijer GA, Rabeneck L, Rutter MD, Valori R, Young GP, Schoen RE; Expert Working Group on ‘Right-sided lesions and interval cancers’, Colorectal Cancer Screening Committee, World Endoscopy Organization.

Gut. 2015 Aug;64(8):1257-67. doi: 10.1136/gutjnl-2014-307992. Epub 2014 Sep 5. Review.


Dietary manipulation of oncogenic microRNA expression in human rectal mucosa: a randomized trial.

Humphreys KJ, Conlon MA, Young GP, Topping DL, Hu Y, Winter JM, Bird AR, Cobiac L, Kennedy NA, Michael MZ, Le Leu RK.

Cancer Prev Res (Phila). 2014 Aug;7(8):786-95. doi: 10.1158/1940-6207.CAPR-14-0053.

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