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Long-term treatment with eteplirsen in nonambulatory patients with Duchenne muscular dystrophy.

Alfano LN, Charleston JS, Connolly AM, Cripe L, Donoghue C, Dracker R, Dworzak J, Eliopoulos H, Frank DE, Lewis S, Lucas K, Lynch J, Milici AJ, Flynt A, Naughton E, Rodino-Klapac LR, Sahenk Z, Schnell FJ, Young GD, Mendell JR, Lowes LP.

Medicine (Baltimore). 2019 Jun;98(26):e15858. doi: 10.1097/MD.0000000000015858.


Implication of ventricular pacing burden and atrial pacing therapies on the progression of atrial fibrillation: A systematic review and meta-analysis of randomized controlled trials.

Munawar DA, Mahajan R, Agbaedeng TA, Thiyagarajah A, Twomey DJ, Khokhar K, O'Shea C, Young GD, Roberts-Thomson KC, Munawar M, Lau DH, Sanders P.

Heart Rhythm. 2019 Aug;16(8):1204-1214. doi: 10.1016/j.hrthm.2019.02.020. Epub 2019 Feb 14.


Validation of a Muscle-Specific Tissue Image Analysis Tool for Quantitative Assessment of Dystrophin Staining in Frozen Muscle Biopsies.

Aeffner F, Faelan C, Moore SA, Moody A, Black JC, Charleston JS, Frank DE, Dworzak J, Piper JK, Ranjitkar M, Wilson K, Kanaly S, Rudmann DG, Lange H, Young GD, Milici AJ.

Arch Pathol Lab Med. 2019 Feb;143(2):197-205. doi: 10.5858/arpa.2017-0536-OA. Epub 2018 Aug 31.


Predicted longevity of contemporary cardiac implantable electronic devices: A call for industry-wide "standardized" reporting.

Munawar DA, Mahajan R, Linz D, Wong GR, Khokhar KB, Thiyagarajah A, Kadhim K, Emami M, Mishima R, Elliott AD, Middeldorp ME, Roberts-Thompson KC, Young GD, Sanders P, Lau DH.

Heart Rhythm. 2018 Dec;15(12):1756-1763. doi: 10.1016/j.hrthm.2018.07.029. Epub 2018 Jul 29.


Magnitude of benefit for adjuvant radiotherapy following minimally invasive surgery in intermediate to high risk HPV-positive oropharyngeal squamous cell carcinoma.

Pasalic D, Funk RK, García JJ, Price DL, Price KA, Harmsen WS, Patel SH, Young GD, Foote RL, Moore EJ, Ma DJ.

Oral Oncol. 2018 Jul;82:181-186. doi: 10.1016/j.oraloncology.2018.05.026. Epub 2018 Jun 6.


Eteplirsen treatment for Duchenne muscular dystrophy: Exon skipping and dystrophin production.

Charleston JS, Schnell FJ, Dworzak J, Donoghue C, Lewis S, Chen L, Young GD, Milici AJ, Voss J, DeAlwis U, Wentworth B, Rodino-Klapac LR, Sahenk Z, Frank D, Mendell JR.

Neurology. 2018 Jun 12;90(24):e2146-e2154. doi: 10.1212/WNL.0000000000005680. Epub 2018 May 11. Erratum in: Neurology. 2018 Sep 25;91(13):637.


Preoperative Localization of Recurrence in the Thyroidectomy Bed Using a Radioactive Iodine125 Seed.

Garner HW, Paz-Fumagalli R, Young GD.

Otolaryngol Head Neck Surg. 2018 Aug;159(2):394-397. doi: 10.1177/0194599818772049. Epub 2018 Apr 24.


Influence of ethnic background on left atrial markers of inflammation, endothelial function and tissue remodelling.

Ruediger CD, John B, Kumar S, Lim HS, Rangnekar G, Roberts-Thomson KC, Young GD, Chase D, Sanders P, Willoughby SR.

Indian Pacing Electrophysiol J. 2018 Jan - Feb;18(1):1-5. doi: 10.1016/j.ipej.2017.08.002. Epub 2017 Aug 30.


Outcomes of persistent and long-standing persistent atrial fibrillation ablation: a systematic review and meta-analysis.

Clarnette JA, Brooks AG, Mahajan R, Elliott AD, Twomey DJ, Pathak RK, Kumar S, Munawar DA, Young GD, Kalman JM, Lau DH, Sanders P.

Europace. 2018 Nov 1;20(FI_3):f366-f376. doi: 10.1093/europace/eux297.


Duchenne and Becker Muscular Dystrophies: A Review of Animal Models, Clinical End Points, and Biomarker Quantification.

Wilson K, Faelan C, Patterson-Kane JC, Rudmann DG, Moore SA, Frank D, Charleston J, Tinsley J, Young GD, Milici AJ.

Toxicol Pathol. 2017 Oct;45(7):961-976. doi: 10.1177/0192623317734823. Epub 2017 Oct 3. Review.


The Gold Standard Paradox in Digital Image Analysis: Manual Versus Automated Scoring as Ground Truth.

Aeffner F, Wilson K, Martin NT, Black JC, Hendriks CLL, Bolon B, Rudmann DG, Gianani R, Koegler SR, Krueger J, Young GD.

Arch Pathol Lab Med. 2017 Sep;141(9):1267-1275. doi: 10.5858/arpa.2016-0386-RA. Epub 2017 May 30. Review.


CT sizing for left atrial appendage closure is associated with favourable outcomes for procedural safety.

Rajwani A, Nelson AJ, Shirazi MG, Disney PJS, Teo KSL, Wong DTL, Young GD, Worthley SG.

Eur Heart J Cardiovasc Imaging. 2017 Dec 1;18(12):1361-1368. doi: 10.1093/ehjci/jew212.


Development of Time- and Voltage-Domain Mapping (V-T-Mapping) to Localize Ventricular Tachycardia Channels During Sinus Rhythm.

Nayyar S, Kuklik P, Ganesan AN, Sullivan TR, Wilson L, Young GD, Sanders P, Roberts-Thomson KC.

Circ Arrhythm Electrophysiol. 2016 Dec;9(12). pii: e004050.


Quantitative assessment of pancreatic cancer precursor lesions in IHC-stained tissue with a tissue image analysis platform.

Aeffner F, Martin NT, Peljto M, Black JC, Major JK, Jangani M, Ports MO, Krueger JS, Young GD.

Lab Invest. 2016 Dec;96(12):1327-1336. doi: 10.1038/labinvest.2016.111. Epub 2016 Oct 24.


Baseline Hemodynamics and Response to Contrast Media During Diagnostic Cardiac Catheterization Predict Adverse Events in Heart Failure Patients.

Denardo SJ, Vock DM, Schmalfuss CM, Young GD, Tcheng JE, O'Connor CM.

Circ Heart Fail. 2016 Jul;9(7). pii: e002529. doi: 10.1161/CIRCHEARTFAILURE.115.002529.


Commentary: Roles for Pathologists in a High-throughput Image Analysis Team.

Aeffner F, Wilson K, Bolon B, Kanaly S, Mahrt CR, Rudmann D, Charles E, Young GD.

Toxicol Pathol. 2016 Aug;44(6):825-34. doi: 10.1177/0192623316653492. Epub 2016 Jun 24.


Left Atrial Appendage Eccentricity and Irregularity Are Associated With Residual Leaks After Percutaneous Closure.

Rajwani A, Shirazi MG, Disney PJS, Wong DTL, Teo KSL, Delacroix S, Chokka RG, Young GD, Worthley SG.

JACC Clin Electrophysiol. 2015 Dec;1(6):478-485. doi: 10.1016/j.jacep.2015.08.006. Epub 2015 Oct 22.


Thrombogenic Risk in Patients With Atrial Fibrillation: Importance of Comorbid Conditions and Intracardiac Changes.

Lim HS, Willoughby SR, Schultz C, Alasady M, Rangnekar G, Dang J, Gan C, Lau DH, Roberts-Thomson KC, Young GD, Worthley MI, Sanders P.

JACC Clin Electrophysiol. 2015 Jun;1(3):210-217. doi: 10.1016/j.jacep.2015.03.011. Epub 2015 Apr 20.


Remote Monitoring of Implantable Cardioverter-Defibrillators: A Systematic Review and Meta-Analysis of Clinical Outcomes.

Parthiban N, Esterman A, Mahajan R, Twomey DJ, Pathak RK, Lau DH, Roberts-Thomson KC, Young GD, Sanders P, Ganesan AN.

J Am Coll Cardiol. 2015 Jun 23;65(24):2591-2600. doi: 10.1016/j.jacc.2015.04.029. Epub 2015 May 13. Review.


Differential Expression of Immune-Regulatory Genes Associated with PD-L1 Display in Melanoma: Implications for PD-1 Pathway Blockade.

Taube JM, Young GD, McMiller TL, Chen S, Salas JT, Pritchard TS, Xu H, Meeker AK, Fan J, Cheadle C, Berger AE, Pardoll DM, Topalian SL.

Clin Cancer Res. 2015 Sep 1;21(17):3969-76. doi: 10.1158/1078-0432.CCR-15-0244. Epub 2015 May 5.


Successful catheter ablation decreases platelet activation and improves endothelial function in patients with atrial fibrillation.

Lim HS, Willoughby SR, Schultz C, Chakrabarty A, Alasady M, Lau DH, Roberts-Thomson KC, Worthley MI, Young GD, Sanders P.

Heart Rhythm. 2014 Nov;11(11):1912-8. doi: 10.1016/j.hrthm.2014.07.030. Epub 2014 Jul 25.


Time course of inflammation, myocardial injury, and prothrombotic response after radiofrequency catheter ablation for atrial fibrillation.

Lim HS, Schultz C, Dang J, Alasady M, Lau DH, Brooks AG, Wong CX, Roberts-Thomson KC, Young GD, Worthley MI, Sanders P, Willoughby SR.

Circ Arrhythm Electrophysiol. 2014 Feb;7(1):83-9. doi: 10.1161/CIRCEP.113.000876. Epub 2014 Jan 20.


High-density mapping of ventricular scar: a comparison of ventricular tachycardia (VT) supporting channels with channels that do not support VT.

Nayyar S, Wilson L, Ganesan AN, Sullivan T, Kuklik P, Chapman D, Brooks AG, Mahajan R, Baumert M, Young GD, Sanders P, Roberts-Thomson KC.

Circ Arrhythm Electrophysiol. 2014 Feb;7(1):90-8. doi: 10.1161/CIRCEP.113.000882. Epub 2014 Jan 1.


U-shaped relationship between tissue docosahexaenoic acid and atrial fibrillation following cardiac surgery.

Metcalf RG, Skuladottir GV, Indridason OS, Sullivan TR, Bjorgvinsdottir L, Sanders P, Arnar DO, Gibson RA, Heidarsdottir R, Cleland LG, Palsson R, Farquharson AL, Young GD, James MJ.

Eur J Clin Nutr. 2014 Jan;68(1):114-8. doi: 10.1038/ejcn.2013.215. Epub 2013 Oct 30.


Aortic stiffness in lone atrial fibrillation: a novel risk factor for arrhythmia recurrence.

Lau DH, Middeldorp ME, Brooks AG, Ganesan AN, Roberts-Thomson KC, Stiles MK, Leong DP, Abed HS, Lim HS, Wong CX, Willoughby SR, Young GD, Kalman JM, Abhayaratna WP, Sanders P.

PLoS One. 2013 Oct 3;8(10):e76776. doi: 10.1371/journal.pone.0076776. eCollection 2013.


Accuracy and clinical outcomes of CT image integration with Carto-Sound compared to electro-anatomical mapping for atrial fibrillation ablation: a randomized controlled study.

Brooks AG, Wilson L, Chia NH, Lau DH, Alasady M, Leong DP, Laborderie J, Roberts-Thomson KC, Young GD, Kalman JM, Sanders P.

Int J Cardiol. 2013 Oct 3;168(3):2774-82. doi: 10.1016/j.ijcard.2013.03.130. Epub 2013 Apr 25.


Paradoxical ventricular activation sequence and ParaHisian entrainment response: do they challenge the diagnosis?

Nayyar S, Young GD, Sanders P, Roberts-Thomson KC.

Circ Arrhythm Electrophysiol. 2013 Feb;6(1):e1-6. doi: 10.1161/CIRCEP.112.971994. No abstract available.


Effect of atrial fibrillation on atrial thrombogenesis in humans: impact of rate and rhythm.

Lim HS, Willoughby SR, Schultz C, Gan C, Alasady M, Lau DH, Leong DP, Brooks AG, Young GD, Kistler PM, Kalman JM, Worthley MI, Sanders P.

J Am Coll Cardiol. 2013 Feb 26;61(8):852-60. doi: 10.1016/j.jacc.2012.11.046. Epub 2013 Jan 16.


Brugada ECG Pattern Unmasked by IV Flecainide in an Individual with Idiopathic Fascicular Ventricular Tachycardia.

Gavin AR, Young GD, McGavigan AD.

Indian Pacing Electrophysiol J. 2013 Jan;13(1):52-5. Epub 2013 Jan 1.


Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma.

Lyford-Pike S, Peng S, Young GD, Taube JM, Westra WH, Akpeng B, Bruno TC, Richmon JD, Wang H, Bishop JA, Chen L, Drake CG, Topalian SL, Pardoll DM, Pai SI.

Cancer Res. 2013 Mar 15;73(6):1733-41. doi: 10.1158/0008-5472.CAN-12-2384. Epub 2013 Jan 3.


Reply: Lead-preserving Strategies for Pacemaker Pocket Infection: Who, When and How?

Nelson AJ, Puri R, Psaltis PJ, Sanders P, Young GD.

Indian Pacing Electrophysiol J. 2012 Nov;12(6):294-6. Epub 2012 Dec 2. No abstract available.


Electrophysiological features of atrial flutter in cardiac sarcoidosis: a report of two cases.

Namboodiri N, Stiles MK, Young GD, Sanders P.

Indian Pacing Electrophysiol J. 2012 Nov;12(6):284-9. Epub 2012 Dec 2.


Tissue pattern recognition error rates and tumor heterogeneity in gastric cancer.

Potts SJ, Huff SE, Lange H, Zakharov V, Eberhard DA, Krueger JS, Hicks DG, Young GD, Johnson T, Whitney-Miller CL.

Appl Immunohistochem Mol Morphol. 2013 Jan;21(1):21-30. doi: 10.1097/PAI.0b013e31825552a3.


Evaluating tumor heterogeneity in immunohistochemistry-stained breast cancer tissue.

Potts SJ, Krueger JS, Landis ND, Eberhard DA, Young GD, Schmechel SC, Lange H.

Lab Invest. 2012 Sep;92(9):1342-57. doi: 10.1038/labinvest.2012.91. Epub 2012 Jul 16.


Dietary omega-3 supplementation exacerbates left ventricular dysfunction in an ovine model of anthracycline-induced cardiotoxicity.

Carbone A, Psaltis PJ, Nelson AJ, Metcalf R, Richardson JD, Weightman M, Thomas A, Finnie JW, Young GD, Worthley SG.

J Card Fail. 2012 Jun;18(6):502-11. doi: 10.1016/j.cardfail.2012.03.005.


Reciprocal regulation controlling the expression of CPI-17, a specific inhibitor protein for the myosin light chain phosphatase in vascular smooth muscle cells.

Kim JI, Urban M, Young GD, Eto M.

Am J Physiol Cell Physiol. 2012 Jul 1;303(1):C58-68. doi: 10.1152/ajpcell.00118.2012. Epub 2012 Apr 25.


Remote monitoring for implantable cardiac electronic devices.

Young GD.

Heart Lung Circ. 2012 Jun;21(6-7):352-7. doi: 10.1016/j.hlc.2012.03.007. Epub 2012 Apr 18. Review.


Real-time CartoSound imaging of the esophagus: a comparison to computed tomography.

Wilson L, Brooks AG, Lau DH, Dimitri H, Sharma G, Lim HS, Alasady M, Young GD, Sanders P.

Int J Cardiol. 2012 May 31;157(2):260-2. doi: 10.1016/j.ijcard.2012.03.037. Epub 2012 Apr 18. No abstract available.


Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape.

Taube JM, Anders RA, Young GD, Xu H, Sharma R, McMiller TL, Chen S, Klein AP, Pardoll DM, Topalian SL, Chen L.

Sci Transl Med. 2012 Mar 28;4(127):127ra37. doi: 10.1126/scitranslmed.3003689.


The evaluation of E-Cadherin and vimentin as biomarkers of clinical outcomes among patients with non-small cell lung cancer treated with erlotinib as second- or third-line therapy.

Richardson F, Young GD, Sennello R, Wolf J, Argast GM, Mercado P, Davies A, Epstein DM, Wacker B.

Anticancer Res. 2012 Feb;32(2):537-52.


Multiplexed measurement of proteins in tissue in a clinical environment.

Potts SJ, Johnson TD, Voelker FA, Lange H, Young GD.

Appl Immunohistochem Mol Morphol. 2011 Dec;19(6):494-8. doi: 10.1097/PAI.0b013e318229ea9e. Review.


Interleukin 6 mediates production of interleukin 10 in metastatic melanoma.

Terai M, Eto M, Young GD, Berd D, Mastrangelo MJ, Tamura Y, Harigaya K, Sato T.

Cancer Immunol Immunother. 2012 Feb;61(2):145-155. doi: 10.1007/s00262-011-1084-5. Epub 2011 Aug 19.


Effect of dietary fish oil on atrial fibrillation after cardiac surgery.

Farquharson AL, Metcalf RG, Sanders P, Stuklis R, Edwards JR, Gibson RA, Cleland LG, Sullivan TR, James MJ, Young GD.

Am J Cardiol. 2011 Sep 15;108(6):851-6. doi: 10.1016/j.amjcard.2011.04.036. Epub 2011 Jul 15.


Povidone-iodine Irrigation - A Possible Alternative To Lead Extraction.

Puri R, Psaltis PJ, Nelson AJ, Sanders P, Young GD.

Indian Pacing Electrophysiol J. 2011 Jul;11(4):115-9. Epub 2011 Jul 3.


Inducible expression of TGFβ, snail and Zeb1 recapitulates EMT in vitro and in vivo in a NSCLC model.

Argast GM, Krueger JS, Thomson S, Sujka-Kwok I, Carey K, Silva S, O'Connor M, Mercado P, Mulford IJ, Young GD, Sennello R, Wild R, Pachter JA, Kan JL, Haley J, Rosenfeld-Franklin M, Epstein DM.

Clin Exp Metastasis. 2011 Oct;28(7):593-614. doi: 10.1007/s10585-011-9394-8. Epub 2011 Jun 4.


Atrial protective effects of n-3 polyunsaturated fatty acids: a long-term study in ovine chronic heart failure.

Lau DH, Psaltis PJ, Carbone A, Kelly DJ, Mackenzie L, Worthington M, Metcalf RG, Kuklik P, Nelson AJ, Zhang Y, Wong CX, Brooks AG, Saint DA, James MJ, Edwards J, Young GD, Worthley SG, Sanders P.

Heart Rhythm. 2011 Apr;8(4):575-82. doi: 10.1016/j.hrthm.2010.12.009. Epub 2010 Dec 8.


The role and impact of quantitative discovery pathology.

Potts SJ, Young GD, Voelker FA.

Drug Discov Today. 2010 Nov;15(21-22):943-50. doi: 10.1016/j.drudis.2010.09.001. Epub 2010 Oct 12. Review.


Characterization of atrial remodeling studied remote from episodes of typical atrial flutter.

Stiles MK, Wong CX, John B, Kuklik P, Brooks AG, Lau DH, Dimitri H, Wilson L, Young GD, Sanders P.

Am J Cardiol. 2010 Aug 15;106(4):528-34. doi: 10.1016/j.amjcard.2010.03.069.


Online dating and conjugal bereavement.

Young GD, Caplan SE.

Death Stud. 2010 Aug;34(7):575-605.


Long-term mechanical consequences of permanent right ventricular pacing: effect of pacing site.

Leong DP, Mitchell AM, Salna I, Brooks AG, Sharma G, Lim HS, Alasady M, Barlow M, Leitch J, Sanders P, Young GD.

J Cardiovasc Electrophysiol. 2010 Oct;21(10):1120-6. doi: 10.1111/j.1540-8167.2010.01804.x.


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