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Items: 1 to 50 of 205

1.

Modelling of endothelial cell migration and angiogenesis in microfluidic cell culture systems.

Kuzmic N, Moore T, Devadas D, Young EWK.

Biomech Model Mechanobiol. 2019 Jan 2. doi: 10.1007/s10237-018-01111-3. [Epub ahead of print]

PMID:
30604299
2.

Deep Learning with Microfluidics for Biotechnology.

Riordon J, Sovilj D, Sanner S, Sinton D, Young EWK.

Trends Biotechnol. 2019 Mar;37(3):310-324. doi: 10.1016/j.tibtech.2018.08.005. Epub 2018 Oct 6. Review.

PMID:
30301571
3.

Microfluidic lung airway-on-a-chip with arrayable suspended gels for studying epithelial and smooth muscle cell interactions.

Humayun M, Chow CW, Young EWK.

Lab Chip. 2018 May 1;18(9):1298-1309. doi: 10.1039/c7lc01357d.

PMID:
29651473
4.

Integrating Population Heterogeneity Indices with Microfluidic Cell-Based Assays.

Moore TA, Li A, Young EWK.

SLAS Discov. 2018 Jun;23(5):459-473. doi: 10.1177/2472555217738533. Epub 2017 Oct 19.

PMID:
29048950
5.

Multiple Myeloma Cell Drug Responses Differ in Thermoplastic vs PDMS Microfluidic Devices.

Moore TA, Brodersen P, Young EWK.

Anal Chem. 2017 Nov 7;89(21):11391-11398. doi: 10.1021/acs.analchem.7b02351. Epub 2017 Oct 17.

PMID:
28972783
6.

Avoiding Preventable Complications in Hospitalized Patients with CKD.

Young EW.

Clin J Am Soc Nephrol. 2017 May 8;12(5):713-714. doi: 10.2215/CJN.03240317. Epub 2017 Apr 27. No abstract available.

7.

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices.

Wan AM, Moore TA, Young EW.

J Vis Exp. 2017 Jan 17;(119). doi: 10.3791/55175.

8.

Single cell functional analysis of multiple myeloma cell populations correlates with diffusion profiles in static microfluidic coculture systems.

Moore TA, Young EW.

Biomicrofluidics. 2016 Jul 15;10(4):044105. doi: 10.1063/1.4958982. eCollection 2016 Jul.

9.

Patients are a virtue: advances in microengineered systems for clinical applications.

Young EW, Moraes C.

Integr Biol (Camb). 2015 Sep;7(9):962-6. doi: 10.1039/c5ib90031j. Epub 2015 Aug 19.

PMID:
26288009
10.

Liquid phase solvent bonding of plastic microfluidic devices assisted by retention grooves.

Wan AM, Sadri A, Young EW.

Lab Chip. 2015;15(18):3785-92. doi: 10.1039/c5lc00729a.

PMID:
26261900
11.

ESRD outcomes and GN subtypes.

Young EW.

Clin J Am Soc Nephrol. 2015 Jul 7;10(7):1117-8. doi: 10.2215/CJN.05390515. Epub 2015 Jun 19. No abstract available.

12.

IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation.

Hwang B, McCool K, Wan J, Wuerzberger-Davis SM, Young EW, Choi EY, Cingolani G, Weaver BA, Miyamoto S.

J Biol Chem. 2015 Jul 17;290(29):17967-84. doi: 10.1074/jbc.M115.645960. Epub 2015 Jun 9.

13.

MicroC(3): an ex vivo microfluidic cis-coculture assay to test chemosensitivity and resistance of patient multiple myeloma cells.

Pak C, Callander NS, Young EW, Titz B, Kim K, Saha S, Chng K, Asimakopoulos F, Beebe DJ, Miyamoto S.

Integr Biol (Camb). 2015 Jun;7(6):643-54. doi: 10.1039/c5ib00071h. Epub 2015 May 22.

14.

Micromilling: a method for ultra-rapid prototyping of plastic microfluidic devices.

Guckenberger DJ, de Groot TE, Wan AM, Beebe DJ, Young EW.

Lab Chip. 2015 Jun 7;15(11):2364-78. doi: 10.1039/c5lc00234f. Review.

15.

Microfluidic multiculture assay to analyze biomolecular signaling in angiogenesis.

Theberge AB, Yu J, Young EW, Ricke WA, Bushman W, Beebe DJ.

Anal Chem. 2015 Mar 17;87(6):3239-46. doi: 10.1021/ac503700f. Epub 2015 Feb 26.

16.

Fluorescence-based assessment of plasma-induced hydrophilicity in microfluidic devices via Nile Red adsorption and depletion.

Guckenberger DJ, Berthier E, Young EW, Beebe DJ.

Anal Chem. 2014 Aug 5;86(15):7258-63. doi: 10.1021/ac501259n. Epub 2014 Jul 17.

17.

Indirect human impacts reverse centuries of carbon sequestration and salt marsh accretion.

Coverdale TC, Brisson CP, Young EW, Yin SF, Donnelly JP, Bertness MD.

PLoS One. 2014 Mar 27;9(3):e93296. doi: 10.1371/journal.pone.0093296. eCollection 2014.

18.

Employee attitudes about moving toward a smoke-free campus at a Veterans Affairs hospital.

Duffy SA, Ewing LA, Welsh DE, Flanagan PS, Waltje AH, Breedveld SB, Young EW.

J Addict Nurs. 2013 Apr-Jun;24(2):82-90. doi: 10.1097/JAN.0b013e318292947e.

PMID:
24621485
19.

New England salt marsh recovery: opportunistic colonization of an invasive species and its non-consumptive effects.

Coverdale TC, Axelman EE, Brisson CP, Young EW, Altieri AH, Bertness MD.

PLoS One. 2013 Aug 29;8(8):e73823. doi: 10.1371/journal.pone.0073823. eCollection 2013.

20.

Effect of ionized serum calcium on outcomes in acute kidney injury needing renal replacement therapy: secondary analysis of the acute renal failure trial network study.

Afshinnia F, Belanger K, Palevsky PM, Young EW.

Ren Fail. 2013;35(10):1310-8. doi: 10.3109/0886022X.2013.828258. Epub 2013 Sep 2.

21.

Advances in microfluidic cell culture systems for studying angiogenesis.

Young EW.

J Lab Autom. 2013 Dec;18(6):427-36. doi: 10.1177/2211068213495206. Epub 2013 Jul 5. Review.

PMID:
23832929
22.

Cells, tissues, and organs on chips: challenges and opportunities for the cancer tumor microenvironment.

Young EW.

Integr Biol (Camb). 2013 Sep;5(9):1096-109. doi: 10.1039/c3ib40076j. Review.

PMID:
23799587
23.

A microscale neuron and Schwann cell coculture model for increasing detection sensitivity of botulinum neurotoxin type A.

Hong WS, Young EW, Tepp WH, Johnson EA, Beebe DJ.

Toxicol Sci. 2013 Jul;134(1):64-72. doi: 10.1093/toxsci/kft082. Epub 2013 Apr 5.

PMID:
23564642
24.

Estimating prevalence of CKD stages 3-5 using health system data.

Shahinian VB, Hedgeman E, Gillespie BW, Young EW, Robinson B, Hsu CY, Plantinga LC, Burrows NR, Eggers P, Saydah S, Powe NR, Saran R; CDC CKD Surveillance System.

Am J Kidney Dis. 2013 Jun;61(6):930-8. doi: 10.1053/j.ajkd.2013.01.018. Epub 2013 Mar 13.

25.

High-content adhesion assay to address limited cell samples.

Warrick JW, Young EW, Schmuck EG, Saupe KW, Beebe DJ.

Integr Biol (Camb). 2013 Apr;5(4):720-7. doi: 10.1039/c3ib20224k. Epub 2013 Feb 21.

26.

Assessment of enhanced autofluorescence and impact on cell microscopy for microfabricated thermoplastic devices.

Young EW, Berthier E, Beebe DJ.

Anal Chem. 2013 Jan 2;85(1):44-9. doi: 10.1021/ac3034773. Epub 2012 Dec 18.

27.

Tubeless microfluidic angiogenesis assay with three-dimensional endothelial-lined microvessels.

Bischel LL, Young EW, Mader BR, Beebe DJ.

Biomaterials. 2013 Feb;34(5):1471-7. doi: 10.1016/j.biomaterials.2012.11.005. Epub 2012 Nov 26.

28.

Microfluidic kit-on-a-lid: a versatile platform for neutrophil chemotaxis assays.

Sackmann EK, Berthier E, Young EW, Shelef MA, Wernimont SA, Huttenlocher A, Beebe DJ.

Blood. 2012 Oct 4;120(14):e45-53. doi: 10.1182/blood-2012-03-416453. Epub 2012 Aug 22.

29.

Induced hydrophobic recovery of oxygen plasma-treated surfaces.

Guckenberger DJ, Berthier E, Young EW, Beebe DJ.

Lab Chip. 2012 Jul 7;12(13):2317-21. doi: 10.1039/c2lc21052e. Epub 2012 May 16.

30.

Engineers are from PDMS-land, Biologists are from Polystyrenia.

Berthier E, Young EW, Beebe D.

Lab Chip. 2012 Apr 7;12(7):1224-37. doi: 10.1039/c2lc20982a. Epub 2012 Feb 8. Review.

PMID:
22318426
31.

Microscale functional cytomics for studying hematologic cancers.

Young EW, Pak C, Kahl BS, Yang DT, Callander NS, Miyamoto S, Beebe DJ.

Blood. 2012 Mar 8;119(10):e76-85. doi: 10.1182/blood-2011-10-384347. Epub 2012 Jan 18.

32.

Rapid prototyping of arrayed microfluidic systems in polystyrene for cell-based assays.

Young EW, Berthier E, Guckenberger DJ, Sackmann E, Lamers C, Meyvantsson I, Huttenlocher A, Beebe DJ.

Anal Chem. 2011 Feb 15;83(4):1408-17. doi: 10.1021/ac102897h. Epub 2011 Jan 24.

33.

Microfluidic cell culture and its application in high-throughput drug screening: cardiotoxicity assay for hERG channels.

Su X, Young EW, Underkofler HA, Kamp TJ, January CT, Beebe DJ.

J Biomol Screen. 2011 Jan;16(1):101-11. doi: 10.1177/1087057110386218. Epub 2010 Dec 3.

34.

Methylglyoxal-modified collagen promotes myofibroblast differentiation.

Yuen A, Laschinger C, Talior I, Lee W, Chan M, Birek J, Young EW, Sivagurunathan K, Won E, Simmons CA, McCulloch CA.

Matrix Biol. 2010 Jul;29(6):537-48. doi: 10.1016/j.matbio.2010.04.004. Epub 2010 Apr 25.

PMID:
20423729
35.

Fundamentals of microfluidic cell culture in controlled microenvironments.

Young EW, Beebe DJ.

Chem Soc Rev. 2010 Mar;39(3):1036-48. doi: 10.1039/b909900j. Epub 2010 Feb 1. Review.

36.

Macro- and microscale fluid flow systems for endothelial cell biology.

Young EW, Simmons CA.

Lab Chip. 2010 Jan 21;10(2):143-60. doi: 10.1039/b913390a. Epub 2009 Oct 9. Review.

PMID:
20066241
37.

Independent and joint associations of nutritional status indicators with mortality risk among chronic hemodialysis patients in the Dialysis Outcomes and Practice Patterns Study (DOPPS).

Lopes AA, Bragg-Gresham JL, Elder SJ, Ginsberg N, Goodkin DA, Pifer T, Lameire N, Marshall MR, Asano Y, Akizawa T, Pisoni RL, Young EW, Port FK.

J Ren Nutr. 2010 Jul;20(4):224-34. doi: 10.1053/j.jrn.2009.10.002. Epub 2010 Jan 8.

PMID:
20060319
38.

Atrial fibrillation in hemodialysis patients: clinical features and associations with anticoagulant therapy.

Wizemann V, Tong L, Satayathum S, Disney A, Akiba T, Fissell RB, Kerr PG, Young EW, Robinson BM.

Kidney Int. 2010 Jun;77(12):1098-106. doi: 10.1038/ki.2009.477. Epub 2010 Jan 6.

39.

Technique for real-time measurements of endothelial permeability in a microfluidic membrane chip using laser-induced fluorescence detection.

Young EW, Watson MW, Srigunapalan S, Wheeler AR, Simmons CA.

Anal Chem. 2010 Feb 1;82(3):808-16. doi: 10.1021/ac901560w.

PMID:
20050596
40.

Establishing a national chronic kidney disease surveillance system for the United States.

Saran R, Hedgeman E, Plantinga L, Burrows NR, Gillespie BW, Young EW, Coresh J, Pavkov M, Williams D, Powe NR; CKD Surveillance Team.

Clin J Am Soc Nephrol. 2010 Jan;5(1):152-61. doi: 10.2215/CJN.05480809. Epub 2009 Dec 3.

41.

Prescription of antihypertensive agents to haemodialysis patients: time trends and associations with patient characteristics, country and survival in the DOPPS.

Lopes AA, Bragg-Gresham JL, Ramirez SP, Andreucci VE, Akiba T, Saito A, Jacobson SH, Robinson BM, Port FK, Mason NA, Young EW.

Nephrol Dial Transplant. 2009 Sep;24(9):2809-16. doi: 10.1093/ndt/gfp212. Epub 2009 May 14.

PMID:
19443648
42.

Rosiglitazone is associated with mortality in chronic hemodialysis patients.

Ramirez SP, Albert JM, Blayney MJ, Tentori F, Goodkin DA, Wolfe RA, Young EW, Bailie GR, Pisoni RL, Port FK.

J Am Soc Nephrol. 2009 May;20(5):1094-101. doi: 10.1681/ASN.2008060579. Epub 2009 Apr 8.

43.

Techniques for isolating and purifying porcine aortic valve endothelial cells.

Cheung WY, Young EW, Simmons CA.

J Heart Valve Dis. 2008 Nov;17(6):674-81.

PMID:
19137801
44.

The survival advantage for haemodialysis patients taking vitamin D is questioned: findings from the Dialysis Outcomes and Practice Patterns Study.

Tentori F, Albert JM, Young EW, Blayney MJ, Robinson BM, Pisoni RL, Akiba T, Greenwood RN, Kimata N, Levin NW, Piera LM, Saran R, Wolfe RA, Port FK.

Nephrol Dial Transplant. 2009 Mar;24(3):963-72. doi: 10.1093/ndt/gfn592. Epub 2008 Nov 21.

PMID:
19028748
45.

Soft lithography: masters on demand.

Abdelgawad M, Watson MW, Young EW, Mudrik JM, Ungrin MD, Wheeler AR.

Lab Chip. 2008 Aug;8(8):1379-85. doi: 10.1039/b804050h. Epub 2008 Jun 24.

PMID:
18651082
46.

High alkaline phosphatase levels in hemodialysis patients are associated with higher risk of hospitalization and death.

Blayney MJ, Pisoni RL, Bragg-Gresham JL, Bommer J, Piera L, Saito A, Akiba T, Keen ML, Young EW, Port FK.

Kidney Int. 2008 Sep;74(5):655-63. doi: 10.1038/ki.2008.248. Epub 2008 Jun 11.

47.

Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: the Dialysis Outcomes and Practice Patterns Study (DOPPS).

Tentori F, Blayney MJ, Albert JM, Gillespie BW, Kerr PG, Bommer J, Young EW, Akizawa T, Akiba T, Pisoni RL, Robinson BM, Port FK.

Am J Kidney Dis. 2008 Sep;52(3):519-30. doi: 10.1053/j.ajkd.2008.03.020. Epub 2008 Jun 2.

PMID:
18514987
48.

Enhanced training in vascular access creation predicts arteriovenous fistula placement and patency in hemodialysis patients: results from the Dialysis Outcomes and Practice Patterns Study.

Saran R, Elder SJ, Goodkin DA, Akiba T, Ethier J, Rayner HC, Saito A, Young EW, Gillespie BW, Merion RM, Pisoni RL.

Ann Surg. 2008 May;247(5):885-91. doi: 10.1097/SLA.0b013e31816c4044.

PMID:
18438128
49.

Substrate architecture and fluid-induced shear stress during chondrocyte seeding: role of alpha5beta1 integrin.

Spiteri CG, Young EW, Simmons CA, Kandel RA, Pilliar RM.

Biomaterials. 2008 Jun;29(16):2477-89. doi: 10.1016/j.biomaterials.2008.01.018. Epub 2008 Mar 7.

PMID:
18314188
50.

Out-of-pocket spending and medication adherence among dialysis patients in twelve countries.

Hirth RA, Greer SL, Albert JM, Young EW, Piette JD.

Health Aff (Millwood). 2008 Jan-Feb;27(1):89-102. doi: 10.1377/hlthaff.27.1.89.

PMID:
18180483

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