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Items: 1 to 50 of 84

1.

The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit.

Young DF, Wignall-Fleming EB, Busse DC, Pickin MJ, Hankinson J, Randall EM, Tavendale A, Davison AJ, Lamont D, Tregoning JS, Goodbourn S, Randall RE.

PLoS Pathog. 2019 Feb 11;15(2):e1007561. doi: 10.1371/journal.ppat.1007561. eCollection 2019 Feb.

2.

Characterization and development of SAPP as a specific peptidic inhibitor that targets Porphyromonas gingivalis.

Ho MH, Lamont RJ, Chazin WJ, Chen H, Young DF, Kumar P, Xie H.

Mol Oral Microbiol. 2018 Dec;33(6):430-439. doi: 10.1111/omi.12246. Epub 2018 Oct 30.

PMID:
30298683
3.

Human IFIT1 Inhibits mRNA Translation of Rubulaviruses but Not Other Members of the Paramyxoviridae Family.

Young DF, Andrejeva J, Li X, Inesta-Vaquera F, Dong C, Cowling VH, Goodbourn S, Randall RE.

J Virol. 2016 Sep 29;90(20):9446-56. doi: 10.1128/JVI.01056-16. Print 2016 Oct 15.

4.

Genome Sequence of the Parainfluenza Virus 5 Strain That Persistently Infects AGS Cells.

Wignall-Fleming E, Young DF, Goodbourn S, Davison AJ, Randall RE.

Genome Announc. 2016 Jul 21;4(4). pii: e00653-16. doi: 10.1128/genomeA.00653-16.

5.

Human IFNAR2 deficiency: Lessons for antiviral immunity.

Duncan CJ, Mohamad SM, Young DF, Skelton AJ, Leahy TR, Munday DC, Butler KM, Morfopoulou S, Brown JR, Hubank M, Connell J, Gavin PJ, McMahon C, Dempsey E, Lynch NE, Jacques TS, Valappil M, Cant AJ, Breuer J, Engelhardt KR, Randall RE, Hambleton S.

Sci Transl Med. 2015 Sep 30;7(307):307ra154. doi: 10.1126/scitranslmed.aac4227.

6.

Stability of the parainfluenza virus 5 genome revealed by deep sequencing of strains isolated from different hosts and following passage in cell culture.

Rima BK, Gatherer D, Young DF, Norsted H, Randall RE, Davison AJ.

J Virol. 2014 Apr;88(7):3826-36. doi: 10.1128/JVI.03351-13. Epub 2014 Jan 22.

7.

Deep sequencing analysis of defective genomes of parainfluenza virus 5 and their role in interferon induction.

Killip MJ, Young DF, Gatherer D, Ross CS, Short JA, Davison AJ, Goodbourn S, Randall RE.

J Virol. 2013 May;87(9):4798-807. doi: 10.1128/JVI.03383-12. Epub 2013 Feb 28.

8.

STAT2 deficiency and susceptibility to viral illness in humans.

Hambleton S, Goodbourn S, Young DF, Dickinson P, Mohamad SM, Valappil M, McGovern N, Cant AJ, Hackett SJ, Ghazal P, Morgan NV, Randall RE.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3053-8. doi: 10.1073/pnas.1220098110. Epub 2013 Feb 7.

9.

Activation of the beta interferon promoter by paramyxoviruses in the absence of virus protein synthesis.

Killip MJ, Young DF, Precious BL, Goodbourn S, Randall RE.

J Gen Virol. 2012 Feb;93(Pt 2):299-307. doi: 10.1099/vir.0.037531-0. Epub 2011 Nov 2.

10.

Failure to activate the IFN-β promoter by a paramyxovirus lacking an interferon antagonist.

Killip MJ, Young DF, Ross CS, Chen S, Goodbourn S, Randall RE.

Virology. 2011 Jun 20;415(1):39-46. doi: 10.1016/j.virol.2011.03.027. Epub 2011 Apr 22.

11.

Heterocellular induction of interferon by negative-sense RNA viruses.

Chen S, Short JA, Young DF, Killip MJ, Schneider M, Goodbourn S, Randall RE.

Virology. 2010 Nov 25;407(2):247-55. doi: 10.1016/j.virol.2010.08.008. Epub 2010 Sep 15.

12.

Mumps virus Enders strain is sensitive to interferon (IFN) despite encoding a functional IFN antagonist.

Young DF, Galiano MC, Lemon K, Chen YH, Andrejeva J, Duprex WP, Rima BK, Randall RE.

J Gen Virol. 2009 Nov;90(Pt 11):2731-8. doi: 10.1099/vir.0.013722-0. Epub 2009 Jul 22.

13.

Parainfluenza virus 5 genomes are located in viral cytoplasmic bodies whilst the virus dismantles the interferon-induced antiviral state of cells.

Carlos TS, Young DF, Schneider M, Simas JP, Randall RE.

J Gen Virol. 2009 Sep;90(Pt 9):2147-56. doi: 10.1099/vir.0.012047-0. Epub 2009 May 20.

14.

STAT-1- and IRF-3-dependent pathways are not essential for repression of ICP0-null mutant herpes simplex virus type 1 in human fibroblasts.

Everett RD, Young DF, Randall RE, Orr A.

J Virol. 2008 Sep;82(17):8871-81. doi: 10.1128/JVI.00613-08. Epub 2008 Jun 25.

15.

AGS and other tissue culture cells can unknowingly be persistently infected with PIV5; a virus that blocks interferon signalling by degrading STAT1.

Young DF, Carlos TS, Hagmaier K, Fan L, Randall RE.

Virology. 2007 Aug 15;365(1):238-40. Epub 2007 May 16.

16.

Analysis of the pH requirement for membrane fusion of different isolates of the paramyxovirus parainfluenza virus 5.

Bissonnette ML, Connolly SA, Young DF, Randall RE, Paterson RG, Lamb RA.

J Virol. 2006 Mar;80(6):3071-7.

17.
18.

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter.

Andrejeva J, Childs KS, Young DF, Carlos TS, Stock N, Goodbourn S, Randall RE.

Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17264-9. Epub 2004 Nov 24.

19.
20.

Virus replication in engineered human cells that do not respond to interferons.

Young DF, Andrejeva L, Livingstone A, Goodbourn S, Lamb RA, Collins PL, Elliott RM, Randall RE.

J Virol. 2003 Feb;77(3):2174-81.

22.

Blood extraction from lancet wounds using vacuum combined with skin stretching.

Cunningham DD, Henning TP, Shain EB, Young DF, Hannig J, Barua E, Lee RC.

J Appl Physiol (1985). 2002 Mar;92(3):1089-96.

24.

Vacuum-assisted lancing of the forearm: an effective and less painful approach to blood glucose monitoring.

Cunningham DD, Henning TP, Shain EB, Young DF, Elstrom TA, Taylor EJ, Schroder SM, Gatcomb PM, Tamborlane WV.

Diabetes Technol Ther. 2000 Winter;2(4):541-8.

PMID:
11469617
25.
26.

Paramyxoviridae use distinct virus-specific mechanisms to circumvent the interferon response.

Young DF, Didcock L, Goodbourn S, Randall RE.

Virology. 2000 Apr 10;269(2):383-90.

27.
28.
29.
30.

Alkaline phosphatase activatable polymeric cross-linkers and their use in the stabilization of proteins.

Bieniarz C, Cornwell MJ, Young DF.

Bioconjug Chem. 1998 May-Jun;9(3):390-8.

PMID:
9576814
32.
33.
34.

Absorption of solar radiation by clouds: observations versus models.

Cess RD, Zhang MH, Minnis P, Corsetti L, Dutton EG, Forgan BW, Garber DP, Gates WL, Hack JJ, Harrison EF, Jing X, Kiehi JT, Long CN, Morcrette JJ, Potter GL, Ramanathan V, Subasilar B, Whitlock CH, Young DF, Zhou Y.

Science. 1995 Jan 27;267(5197):496-9.

PMID:
17788783
35.
36.

Thiolate and phosphorothioate functionalized fluoresceins and their use as fluorescent labels.

Bieniarz C, Young DF, Cornwell MJ.

Bioconjug Chem. 1994 Jan-Feb;5(1):31-9.

PMID:
8199232
37.

Development of a direct systolic cardiac augmentation device.

Frake BC, Young DF, Kudej RK.

Biomed Sci Instrum. 1994;30:39-44.

PMID:
7948647
38.

Computer simulation of arterial flow with applications to arterial and aortic stenoses.

Stergiopulos N, Young DF, Rogge TR.

J Biomech. 1992 Dec;25(12):1477-88.

PMID:
1491023
39.
40.
41.

Numerical study of arterial flow during sustained external acceleration.

Cornet DA, Young DF, Rogge TR.

Biomed Sci Instrum. 1992;28:135-43.

PMID:
1643217
42.

Identification of an epitope on the P and V proteins of simian virus 5 that distinguishes between two isolates with different biological characteristics.

Southern JA, Young DF, Heaney F, Baumgärtner WK, Randall RE.

J Gen Virol. 1991 Jul;72 ( Pt 7):1551-7.

PMID:
1713260
44.

Numerical study of pressure and flow propagation in arteries.

Stergiopulos N, Young DF, Rogge TR.

Biomed Sci Instrum. 1991;27:93-104.

PMID:
2065183
45.
46.

Use of ultrasonic Doppler waveforms to estimate changes in uterine artery blood flow and vessel compliance.

Waite LR, Ford SP, Young DF, Conley AJ.

J Anim Sci. 1990 Aug;68(8):2450-8.

PMID:
2144852
47.
48.

Computer simulation of blood flow in the human arm.

Balar SD, Rogge TR, Young DF.

J Biomech. 1989;22(6-7):691-7.

PMID:
2808450
49.

Prediction of arterial compliance from pressure and flow waveforms.

Drues ME, Young DF.

Biomed Sci Instrum. 1989;25:233-8.

PMID:
2742971
50.

Microcomputer-based analyzer for the assessment of Doppler ultrasound blood velocity waveforms.

Waite LR, Young DF, Ford SP.

Biomed Sci Instrum. 1989;25:113-8.

PMID:
2663096

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