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Simulation of semidilute polymer solutions in planar extensional flow via conformationally averaged Brownian noise.

Young CD, Sing CE.

J Chem Phys. 2019 Sep 28;151(12):124907. doi: 10.1063/1.5122811.


Response to Letter to the Editor: "Macrophages Promote Growth of Squamous Cancer Independent of T Cells".

Wu FL, Zhou HM, Young CD, Wang XJ.

J Dent Res. 2019 Nov;98(12):1398. doi: 10.1177/0022034519873655. Epub 2019 Sep 4. No abstract available.


Ring polymer dynamics and tumbling-stretch transitions in planar mixed flows.

Young CD, Qian JR, Marvin M, Sing CE.

Phys Rev E. 2019 Jun;99(6-1):062502. doi: 10.1103/PhysRevE.99.062502.


Macrophages Promote Growth of Squamous Cancer Independent of T cells.

Wu FL, Nolan K, Strait AA, Bian L, Nguyen KA, Wang JH, Jimeno A, Zhou HM, Young CD, Wang XJ.

J Dent Res. 2019 Jul;98(8):896-903. doi: 10.1177/0022034519854734. Epub 2019 Jun 12.


High-stability pH sensing with a few-layer MoS2 field-effect transistor.

Wang H, Zhao P, Zeng X, Young CD, Hu W.

Nanotechnology. 2019 Sep 13;30(37):375203. doi: 10.1088/1361-6528/ab277b. Epub 2019 Jun 6.


Lessons learned from SMAD4 loss in squamous cell carcinomas.

Hernandez AL, Young CD, Wang JH, Wang XJ.

Mol Carcinog. 2019 Sep;58(9):1648-1655. doi: 10.1002/mc.23049. Epub 2019 May 29. Review.


Sperm can act as vectors for HIV-1 transmission into vaginal and cervical epithelial cells.

Young CD, Tatieng S, Kongmanas K, Fongmoon D, Lomenick B, Yoon AJ, Kiattiburut W, Compostella F, Faull KF, Suree N, Angel JB, Tanphaichitr N.

Am J Reprod Immunol. 2019 Jul;82(1):e13129. doi: 10.1111/aji.13129. Epub 2019 May 26.


Correction: Association of FGFR1 with ERα Maintains Ligand-Independent ER Transcription and Mediates Resistance to Estrogen Deprivation in ER+ Breast Cancer.

Formisano L, Stauffer KM, Young CD, Bhola NE, Guerrero-Zotano AL, Jansen VM, Estrada MM, Hutchinson KE, Giltnane JM, Schwarz LJ, Lu Y, Balko JM, Deas O, Cairo S, Judde JG, Mayer IA, Sanders M, Dugger TC, Bianco R, Stricker T, Arteaga CL.

Clin Cancer Res. 2019 Feb 15;25(4):1433. doi: 10.1158/1078-0432.CCR-18-4268. No abstract available.


Stress-Induced Crystallization of Thin Hf1- XZr XO2 Films: The Origin of Enhanced Energy Density with Minimized Energy Loss for Lead-Free Electrostatic Energy Storage Applications.

Kim SJ, Mohan J, Lee JS, Kim HS, Lee J, Young CD, Colombo L, Summerfelt SR, San T, Kim J.

ACS Appl Mater Interfaces. 2019 Feb 6;11(5):5208-5214. doi: 10.1021/acsami.8b17211. Epub 2019 Jan 28.


Factors in cattle affecting embryo transfer pregnancies in recipient animals.

Roper DA, Schrick FN, Edwards JL, Hopkins FM, Prado TM, Wilkerson JB, Saxton AM, Young CD, Smith WB.

Anim Reprod Sci. 2018 Dec;199:79-83. doi: 10.1016/j.anireprosci.2018.11.001. Epub 2018 Nov 6.


Smad7 Ameliorates TGF-β-Mediated Skin Inflammation and Associated Wound Healing Defects but Not Susceptibility to Experimental Skin Carcinogenesis.

Li F, Bian L, Iriyama S, Jian Z, Fan B, Luo J, Wang DD, Young CD, Han G, Wang XJ.

J Invest Dermatol. 2019 Apr;139(4):940-950. doi: 10.1016/j.jid.2018.10.031. Epub 2018 Nov 10.


Conformationally averaged iterative Brownian dynamics simulations of semidilute polymer solutions.

Young CD, Marvin M, Sing CE.

J Chem Phys. 2018 Nov 7;149(17):174904. doi: 10.1063/1.5041453.


Smad7 Promotes Healing of Radiotherapy-Induced Oral Mucositis without Compromising Oral Cancer Therapy in a Xenograft Mouse Model.

Luo J, Bian L, Blevins MA, Wang D, Liang C, Du D, Wu F, Holwerda B, Zhao R, Raben D, Zhou H, Young CD, Wang XJ.

Clin Cancer Res. 2019 Jan 15;25(2):808-818. doi: 10.1158/1078-0432.CCR-18-1081. Epub 2018 Sep 5.


Mouse Models for Studying Oral Cancer: Impact in the Era of Cancer Immunotherapy.

Luo JJ, Young CD, Zhou HM, Wang XJ.

J Dent Res. 2018 Jun;97(6):683-690. doi: 10.1177/0022034518767635. Epub 2018 Apr 12. Review.


Developing Visual Thinking in the Electronic Health Record.

Boyd AD, Young CD, Amatayakul M, Dieter MG, Pawola LM.

Stud Health Technol Inform. 2017;245:308-312.


An ERBB1-3 Neutralizing Antibody Mixture With High Activity Against Drug-Resistant HER2+ Breast Cancers With ERBB Ligand Overexpression.

Schwarz LJ, Hutchinson KE, Rexer BN, Estrada MV, Gonzalez Ericsson PI, Sanders ME, Dugger TC, Formisano L, Guerrero-Zotano A, Red-Brewer M, Young CD, Lantto J, Pedersen MW, Kragh M, Horak ID, Arteaga CL.

J Natl Cancer Inst. 2017 Nov 1;109(11). doi: 10.1093/jnci/djx065.


Global strain field mapping of a particle-laden interface using digital image correlation.

Vora SR, Bognet B, Patanwala HS, Young CD, Chang SY, Daux V, Ma AWK.

J Colloid Interface Sci. 2018 Jan 1;509:94-101. doi: 10.1016/j.jcis.2017.08.082. Epub 2017 Sep 1.


Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance.

Giltnane JM, Hutchinson KE, Stricker TP, Formisano L, Young CD, Estrada MV, Nixon MJ, Du L, Sanchez V, Ericsson PG, Kuba MG, Sanders ME, Mu XJ, Van Allen EM, Wagle N, Mayer IA, Abramson V, Gόmez H, Rizzo M, Toy W, Chandarlapaty S, Mayer EL, Christiansen J, Murphy D, Fitzgerald K, Wang K, Ross JS, Miller VA, Stephens PJ, Yelensky R, Garraway L, Shyr Y, Meszoely I, Balko JM, Arteaga CL.

Sci Transl Med. 2017 Aug 9;9(402). pii: eaai7993. doi: 10.1126/scitranslmed.aai7993. Erratum in: Sci Transl Med. 2019 Feb 13;11(479):.


Association of FGFR1 with ERα Maintains Ligand-Independent ER Transcription and Mediates Resistance to Estrogen Deprivation in ER+ Breast Cancer.

Formisano L, Stauffer KM, Young CD, Bhola NE, Guerrero-Zotano AL, Jansen VM, Estrada MM, Hutchinson KE, Giltnane JM, Schwarz LJ, Lu Y, Balko JM, Deas O, Cairo S, Judde JG, Mayer IA, Sanders M, Dugger TC, Bianco R, Stricker T, Arteaga CL.

Clin Cancer Res. 2017 Oct 15;23(20):6138-6150. doi: 10.1158/1078-0432.CCR-17-1232. Epub 2017 Jul 27. Erratum in: Clin Cancer Res. 2019 Feb 15;25(4):1433.


An iterative method for hydrodynamic interactions in Brownian dynamics simulations of polymer dynamics.

Miao L, Young CD, Sing CE.

J Chem Phys. 2017 Jul 14;147(2):024904. doi: 10.1063/1.4993218.


Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.

Morrison Joly M, Williams MM, Hicks DJ, Jones B, Sanchez V, Young CD, Sarbassov DD, Muller WJ, Brantley-Sieders D, Cook RS.

Breast Cancer Res. 2017 Jun 30;19(1):74. doi: 10.1186/s13058-017-0868-8.


Probing Interface Defects in Top-Gated MoS2 Transistors with Impedance Spectroscopy.

Zhao P, Azcatl A, Gomeniuk YY, Bolshakov P, Schmidt M, McDonnell SJ, Hinkle CL, Hurley PK, Wallace RM, Young CD.

ACS Appl Mater Interfaces. 2017 Jul 19;9(28):24348-24356. doi: 10.1021/acsami.7b06204. Epub 2017 Jul 6.


Short communication: A reproductive tract scoring system to manage fertility in lactating dairy cows.

Young CD, Schrick FN, Pohler KG, Saxton AM, Di Croce FA, Roper DA, Wilkerson JB, Edwards JL.

J Dairy Sci. 2017 Jul;100(7):5922-5927. doi: 10.3168/jds.2016-12288. Epub 2017 May 3.


Discovery of the aryl heterocyclic amine insecticides: synthesis, insecticidal activity, field results, mode of action and bioavailability of a leading field candidate.

Dent WH 3rd, Pobanz MA, Geng C, Sparks TC, Watson GB, Letherer TJ, Beavers KW, Young CD, Adelfinskaya YA, Ross RR, Whiteker G, Renga J.

Pest Manag Sci. 2017 Apr;73(4):774-781. doi: 10.1002/ps.4431. Epub 2016 Oct 26.


Dual inhibition of Type I and Type III PI3 kinases increases tumor cell apoptosis in HER2+ breast cancers.

Young CD, Arteaga CL, Cook RS.

Breast Cancer Res. 2015 Dec 4;17:148. doi: 10.1186/s13058-015-0656-2.


Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth.

Hover LD, Young CD, Bhola NE, Wilson AJ, Khabele D, Hong CC, Moses HL, Owens P.

Cancer Lett. 2015 Nov 1;368(1):79-87. doi: 10.1016/j.canlet.2015.07.032. Epub 2015 Jul 30.


mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.

Morrison MM, Young CD, Wang S, Sobolik T, Sanchez VM, Hicks DJ, Cook RS, Brantley-Sieders DM.

PLoS Genet. 2015 Jul 1;11(7):e1005291. doi: 10.1371/journal.pgen.1005291. eCollection 2015 Jul.


Activating PIK3CA Mutations Induce an Epidermal Growth Factor Receptor (EGFR)/Extracellular Signal-regulated Kinase (ERK) Paracrine Signaling Axis in Basal-like Breast Cancer.

Young CD, Zimmerman LJ, Hoshino D, Formisano L, Hanker AB, Gatza ML, Morrison MM, Moore PD, Whitwell CA, Dave B, Stricker T, Bhola NE, Silva GO, Patel P, Brantley-Sieders DM, Levin M, Horiates M, Palma NA, Wang K, Stephens PJ, Perou CM, Weaver AM, O'Shaughnessy JA, Chang JC, Park BH, Liebler DC, Cook RS, Arteaga CL.

Mol Cell Proteomics. 2015 Jul;14(7):1959-76. doi: 10.1074/mcp.M115.049783. Epub 2015 May 7.


Antimicrobial host defence peptide, LL-37, as a potential vaginal contraceptive.

Srakaew N, Young CD, Sae-wu A, Xu H, Quesnel KL, di Brisco R, Kongmanas K, Fongmoon D, Hommalai G, Weerachatyanukul W, Hall SH, Zhang YL, Panza L, Franchini L, Compostella F, Pearson TW, Hancock RE, Oko RJ, Hermo LS, Tanphaichitr N.

Hum Reprod. 2014 Apr;29(4):683-96. doi: 10.1093/humrep/deu018. Epub 2014 Feb 18.


Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets.

Balko JM, Giltnane JM, Wang K, Schwarz LJ, Young CD, Cook RS, Owens P, Sanders ME, Kuba MG, Sánchez V, Kurupi R, Moore PD, Pinto JA, Doimi FD, Gómez H, Horiuchi D, Goga A, Lehmann BD, Bauer JA, Pietenpol JA, Ross JS, Palmer GA, Yelensky R, Cronin M, Miller VA, Stephens PJ, Arteaga CL.

Cancer Discov. 2014 Feb;4(2):232-45. doi: 10.1158/2159-8290.CD-13-0286. Epub 2013 Dec 19.


Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies.

Hanker AB, Pfefferle AD, Balko JM, Kuba MG, Young CD, Sánchez V, Sutton CR, Cheng H, Perou CM, Zhao JJ, Cook RS, Arteaga CL.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14372-7. doi: 10.1073/pnas.1303204110. Epub 2013 Aug 12.


Conditional loss of ErbB3 delays mammary gland hyperplasia induced by mutant PIK3CA without affecting mammary tumor latency, gene expression, or signaling.

Young CD, Pfefferle AD, Owens P, Kuba MG, Rexer BN, Balko JM, Sánchez V, Cheng H, Perou CM, Zhao JJ, Cook RS, Arteaga CL.

Cancer Res. 2013 Jul 1;73(13):4075-85. doi: 10.1158/0008-5472.CAN-12-4579. Epub 2013 Apr 30.


HIV infection of thymocytes inhibits IL-7 activity without altering CD127 expression.

Young CD, Angel JB.

Retrovirology. 2011 Sep 16;8:72. doi: 10.1186/1742-4690-8-72.


Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo.

Young CD, Lewis AS, Rudolph MC, Ruehle MD, Jackman MR, Yun UJ, Ilkun O, Pereira R, Abel ED, Anderson SM.

PLoS One. 2011;6(8):e23205. doi: 10.1371/journal.pone.0023205. Epub 2011 Aug 3.


Novel nicotinic action of the sulfoximine insecticide sulfoxaflor.

Watson GB, Loso MR, Babcock JM, Hasler JM, Letherer TJ, Young CD, Zhu Y, Casida JE, Sparks TC.

Insect Biochem Mol Biol. 2011 Jul;41(7):432-9. doi: 10.1016/j.ibmb.2011.01.009. Epub 2011 Feb 4.


A vitamin D receptor-alkylating derivative of 1α,25-dihydroxyvitamin D3 inhibits growth of human kidney cancer cells and suppresses tumor growth.

Lambert JR, Eddy VJ, Young CD, Persons KS, Sarkar S, Kelly JA, Genova E, Lucia MS, Faller DV, Ray R.

Cancer Prev Res (Phila). 2010 Dec;3(12):1596-607. doi: 10.1158/1940-6207.CAPR-10-0122.


AKT regulates BRCA1 stability in response to hormone signaling.

Nelson AC, Lyons TR, Young CD, Hansen KC, Anderson SM, Holt JT.

Mol Cell Endocrinol. 2010 May 5;319(1-2):129-42. doi: 10.1016/j.mce.2010.01.019. Epub 2010 Jan 18.


Rah, rah, ROS: metabolic changes caused by loss of adhesion induce cell death.

Young CD, Anderson SM.

Breast Cancer Res. 2009;11(6):307. doi: 10.1186/bcr2417. Epub 2009 Nov 18.


Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3.

Young CD, Nolte EC, Lewis A, Serkova NJ, Anderson SM.

Breast Cancer Res. 2008;10(4):R70. doi: 10.1186/bcr2132. Epub 2008 Aug 13.


CpG increases vaccine antigen-specific cell-mediated immunity when administered with hepatitis B vaccine in HIV infection.

Angel JB, Cooper CL, Clinch J, Young CD, Chenier A, Parato KG, Lautru M, Davis H, Cameron DW.

J Immune Based Ther Vaccines. 2008 Aug 12;6:4. doi: 10.1186/1476-8518-6-4.


Sugar and fat - that's where it's at: metabolic changes in tumors.

Young CD, Anderson SM.

Breast Cancer Res. 2008;10(1):202. doi: 10.1186/bcr1852. Epub 2008 Feb 20. Review.


Mechanistic and pharmacodynamic studies of a 25-hydroxyvitamin D3 derivative in prostate cancer cells.

Lambert JR, Young CD, Persons KS, Ray R.

Biochem Biophys Res Commun. 2007 Sep 14;361(1):189-95. Epub 2007 Jul 16.


Optimization of culture and storage conditions for an in vitro system to evaluate thymocyte phenotype and function.

Young CD, Angel JB.

J Immunol Methods. 2006 May 30;312(1-2):157-66. Epub 2006 Apr 7.


Long-term follow-up of a cohort of HIV-infected patients who discontinued maintenance therapy for cytomegalovirus retinitis.

Walmsley SL, Raboud J, Angel JB, Mazzulli T, Shen S, Casciaro L, Young CD, Moussa G, Gough K, Rachlis A, Hopkins J.

HIV Clin Trials. 2006 Jan-Feb;7(1):1-9.


Association of the frequency of respiratory illness in early childhood with a change in the distribution of blood lymphocyte subpopulations.

Karsh J, Angel JB, Young CD, Sahni V, Judek S, Miller D, Dales RE.

Allergy Asthma Clin Immunol. 2005 Dec 15;1(4):135-41. doi: 10.1186/1710-1492-1-4-135. Epub 2005 Dec 15.


Measuring the impact of a public health data training program.

Irani PR, Byrne C, Medvesky MG, Young CD, Waltz EC.

J Public Health Manag Pract. 2002 Jul;8(4):54-62.


A zero PSA slope in posttreatment prostate-specific antigen supports cure of patients with long-term follow-up after external beam radiotherapy for localized prostate cancer.

Takamiya R, Weinberg V, Young CD, Sandler H, McLaughlin P, Roach M 3rd.

Int J Radiat Oncol Biol Phys. 2003 Jul 15;56(4):1073-8.


Normalization of natural killer cell function and phenotype with effective anti-HIV therapy and the role of IL-10.

Parato KG, Kumar A, Badley AD, Sanchez-Dardon JL, Chambers KA, Young CD, Lim WT, Kravcik S, Cameron DW, Angel JB.

AIDS. 2002 Jun 14;16(9):1251-6.


Extragenic suppressors of the nimX2(cdc2) mutation of Aspergillus nidulans affect nuclear division, septation and conidiation.

McGuire SL, Roe DL, Carter BW, Carter RL, Grace SP, Hays PL, Lang GA, Mamaril JL, McElvaine AT, Payne AM, Schrader MD, Wahrle SE, Young CD.

Genetics. 2000 Dec;156(4):1573-84.

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