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Laminin-driven Epac/Rap1 regulation of epithelial barriers on decellularized matrix.

Young BM, Shankar K, Tho CK, Pellegrino AR, Heise RL.

Acta Biomater. 2019 Oct 5. pii: S1742-7061(19)30676-2. doi: 10.1016/j.actbio.2019.10.009. [Epub ahead of print]


Reactivation of Chronic Hepatitis C as a Potential Trigger for Guillain-Barré Syndrome.

Molokwu O, Young BM, Singh M, Menezes K, Mian R.

Cureus. 2019 Jul 26;11(7):e5244. doi: 10.7759/cureus.5244.


Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP.

Byndloss MX, Tsai AY, Walker GT, Miller CN, Young BM, English BC, Seyffert N, Kerrinnes T, de Jong MF, Atluri VL, Winter MG, Celli J, Tsolis RM.

MBio. 2019 Jul 23;10(4). pii: e01538-19. doi: 10.1128/mBio.01538-19.


Expression of a CARD Slows the Retinal Degeneration of a Geographic Atrophy Mouse Model.

Young BM, Jones K, Massengill MT, Walsh E, Li H, Lewin AS, Ildefonso CJ.

Mol Ther Methods Clin Dev. 2019 Jun 12;14:113-125. doi: 10.1016/j.omtm.2019.06.001. eCollection 2019 Sep 13.


Ipsilesional Mu Rhythm Desynchronization and Changes in Motor Behavior Following Post Stroke BCI Intervention for Motor Rehabilitation.

Remsik AB, Williams L Jr, Gjini K, Dodd K, Thoma J, Jacobson T, Walczak M, McMillan M, Rajan S, Young BM, Nigogosyan Z, Advani H, Mohanty R, Tellapragada N, Allen J, Mazrooyisebdani M, Walton LM, van Kan PLE, Kang TJ, Sattin JA, Nair VA, Edwards DF, Williams JC, Prabhakaran V.

Front Neurosci. 2019 Mar 6;13:53. doi: 10.3389/fnins.2019.00053. eCollection 2019.


Benchmarking the Current Codex Alimentarius International Estimated Short-Term Intake Equations and the Proposed New Equations.

Cleveland CB, Fleming CR, Johnston JE, Klemens AS, Young BM.

J Agric Food Chem. 2019 Mar 27;67(12):3432-3447. doi: 10.1021/acs.jafc.8b05547. Epub 2019 Mar 14.


Evaluation of Changes in the Motor Network Following BCI Therapy Based on Graph Theory Analysis.

Mazrooyisebdani M, Nair VA, Loh PL, Remsik AB, Young BM, Moreno BS, Dodd KC, Kang TJ, William JC, Prabhakaran V.

Front Neurosci. 2018 Nov 27;12:861. doi: 10.3389/fnins.2018.00861. eCollection 2018.


Behavioral Outcomes Following Brain-Computer Interface Intervention for Upper Extremity Rehabilitation in Stroke: A Randomized Controlled Trial.

Remsik AB, Dodd K, Williams L Jr, Thoma J, Jacobson T, Allen JD, Advani H, Mohanty R, McMillan M, Rajan S, Walczak M, Young BM, Nigogosyan Z, Rivera CA, Mazrooyisebdani M, Tellapragada N, Walton LM, Gjini K, van Kan PLE, Kang TJ, Sattin JA, Nair VA, Edwards DF, Williams JC, Prabhakaran V.

Front Neurosci. 2018 Nov 8;12:752. doi: 10.3389/fnins.2018.00752. eCollection 2018.


Early Findings on Functional Connectivity Correlates of Behavioral Outcomes of Brain-Computer Interface Stroke Rehabilitation Using Machine Learning.

Mohanty R, Sinha AM, Remsik AB, Dodd KC, Young BM, Jacobson T, McMillan M, Thoma J, Advani H, Nair VA, Kang TJ, Caldera K, Edwards DF, Williams JC, Prabhakaran V.

Front Neurosci. 2018 Sep 11;12:624. doi: 10.3389/fnins.2018.00624. eCollection 2018.


RNA based individualized drug selection in breast cancer patients without patient-matched normal tissue.

Forster M, Mark A, Egberts F, Rosati E, Rodriguez E, Stanulla M, Bauerschlag D, Schem C, Maass N, Amallraja A, Murphy KK, Prouse BR, Sulaiman RA, Young BM, Mathiak M, Hemmrich-Stanisak G, Ellinghaus D, Weidinger S, Rosenstiel P, Arnold N, Leyland-Jones B, Williams CB, Franke A, Meißner T.

Oncotarget. 2018 Aug 17;9(64):32362-32372. doi: 10.18632/oncotarget.25981. eCollection 2018 Aug 17.


Machine Learning Classification to Identify the Stage of Brain-Computer Interface Therapy for Stroke Rehabilitation Using Functional Connectivity.

Mohanty R, Sinha AM, Remsik AB, Dodd KC, Young BM, Jacobson T, McMillan M, Thoma J, Advani H, Nair VA, Kang TJ, Caldera K, Edwards DF, Williams JC, Prabhakaran V.

Front Neurosci. 2018 May 29;12:353. doi: 10.3389/fnins.2018.00353. eCollection 2018.


The role of ZA channel water-mediated interactions in the design of bromodomain-selective BET inhibitors.

Bharatham N, Slavish PJ, Shadrick WR, Young BM, Shelat AA.

J Mol Graph Model. 2018 May;81:197-210. doi: 10.1016/j.jmgm.2018.03.005. Epub 2018 Mar 22.


Utilization of Host Polyamines in Alternatively Activated Macrophages Promotes Chronic Infection by Brucella abortus.

Kerrinnes T, Winter MG, Young BM, Diaz-Ochoa VE, Winter SE, Tsolis RM.

Infect Immun. 2018 Feb 20;86(3). pii: e00458-17. doi: 10.1128/IAI.00458-17. Print 2018 Mar.


Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors.

Shadrick WR, Slavish PJ, Chai SC, Waddell B, Connelly M, Low JA, Tallant C, Young BM, Bharatham N, Knapp S, Boyd VA, Morfouace M, Roussel MF, Chen T, Lee RE, Kiplin Guy R, Shelat AA, Potter PM.

Bioorg Med Chem. 2018 Jan 1;26(1):25-36. doi: 10.1016/j.bmc.2017.10.042. Epub 2017 Nov 4.


A novel role for primary cilia in airway remodeling.

Trempus CS, Song W, Lazrak A, Yu Z, Creighton JR, Young BM, Heise RL, Yu YR, Ingram JL, Tighe RM, Matalon S, Garantziotis S.

Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L328-L338. doi: 10.1152/ajplung.00284.2016. Epub 2017 May 4.


Tunable Hydrogels from Pulmonary Extracellular Matrix for 3D Cell Culture.

Link PA, Pouliot RA, Mikhaiel NS, Young BM, Heise RL.

J Vis Exp. 2017 Jan 17;(119). doi: 10.3791/55094.


Differential Contribution of Transmembrane Domains IV, V, VI, and VII to Human Angiotensin II Type 1 Receptor Homomer Formation.

Young BM, Nguyen E, Chedrawe MA, Rainey JK, Dupré DJ.

J Biol Chem. 2017 Feb 24;292(8):3341-3350. doi: 10.1074/jbc.M116.750380. Epub 2017 Jan 17.


Structural Imaging Changes and Behavioral Correlates in Patients with Crohn's Disease in Remission.

Nair VA, Beniwal-Patel P, Mbah I, Young BM, Prabhakaran V, Saha S.

Front Hum Neurosci. 2016 Sep 16;10:460. eCollection 2016.


Brain-Computer Interface Training after Stroke Affects Patterns of Brain-Behavior Relationships in Corticospinal Motor Fibers.

Young BM, Stamm JM, Song J, Remsik AB, Nair VA, Tyler ME, Edwards DF, Caldera K, Sattin JA, Williams JC, Prabhakaran V.

Front Hum Neurosci. 2016 Sep 16;10:457. eCollection 2016.


Differing Patterns of Altered Slow-5 Oscillations in Healthy Aging and Ischemic Stroke.

La C, Mossahebi P, Nair VA, Young BM, Stamm J, Birn R, Meyerand ME, Prabhakaran V.

Front Hum Neurosci. 2016 Apr 13;10:156. doi: 10.3389/fnhum.2016.00156. eCollection 2016.


Implication of the Slow-5 Oscillations in the Disruption of the Default-Mode Network in Healthy Aging and Stroke.

La C, Nair VA, Mossahebi P, Young BM, Chacon M, Jensen M, Birn RM, Meyerand ME, Prabhakaran V.

Brain Connect. 2016 Jul;6(6):482-95. doi: 10.1089/brain.2015.0375.


Effects of Estrogen Receptor and Human Epidermal Growth Factor Receptor-2 Levels on the Efficacy of Trastuzumab: A Secondary Analysis of the HERA Trial.

Loi S, Dafni U, Karlis D, Polydoropoulou V, Young BM, Willis S, Long B, de Azambuja E, Sotiriou C, Viale G, Rüschoff J, Piccart MJ, Dowsett M, Michiels S, Leyland-Jones B.

JAMA Oncol. 2016 Aug 1;2(8):1040-7. doi: 10.1001/jamaoncol.2016.0339.


NOD1 and NOD2 signalling links ER stress with inflammation.

Keestra-Gounder AM, Byndloss MX, Seyffert N, Young BM, Chávez-Arroyo A, Tsai AY, Cevallos SA, Winter MG, Pham OH, Tiffany CR, de Jong MF, Kerrinnes T, Ravindran R, Luciw PA, McSorley SJ, Bäumler AJ, Tsolis RM.

Nature. 2016 Apr 21;532(7599):394-7. doi: 10.1038/nature17631. Epub 2016 Mar 23.


Optimization of a Novel Series of Ataxia-Telangiectasia Mutated Kinase Inhibitors as Potential Radiosensitizing Agents.

Min J, Guo K, Suryadevara PK, Zhu F, Holbrook G, Chen Y, Feau C, Young BM, Lemoff A, Connelly MC, Kastan MB, Guy RK.

J Med Chem. 2016 Jan 28;59(2):559-77. doi: 10.1021/acs.jmedchem.5b01092. Epub 2016 Jan 12.


Phospholipase A1 modulates the cell envelope phospholipid content of Brucella melitensis, contributing to polymyxin resistance and pathogenicity.

Kerrinnes T, Young BM, Leon C, Roux CM, Tran L, Atluri VL, Winter MG, Tsolis RM.

Antimicrob Agents Chemother. 2015 Nov;59(11):6717-24. doi: 10.1128/AAC.00792-15. Epub 2015 Aug 17.


Dose-response relationships using brain-computer interface technology impact stroke rehabilitation.

Young BM, Nigogosyan Z, Walton LM, Remsik A, Song J, Nair VA, Tyler ME, Edwards DF, Caldera K, Sattin JA, Williams JC, Prabhakaran V.

Front Hum Neurosci. 2015 Jun 23;9:361. doi: 10.3389/fnhum.2015.00361. eCollection 2015.


DTI measures track and predict motor function outcomes in stroke rehabilitation utilizing BCI technology.

Song J, Nair VA, Young BM, Walton LM, Nigogosyan Z, Remsik A, Tyler ME, Farrar-Edwards D, Caldera KE, Sattin JA, Williams JC, Prabhakaran V.

Front Hum Neurosci. 2015 Apr 27;9:195. doi: 10.3389/fnhum.2015.00195. eCollection 2015.


Functional connectivity changes in the language network during stroke recovery.

Nair VA, Young BM, La C, Reiter P, Nadkarni TN, Song J, Vergun S, Addepally NS, Mylavarapu K, Swartz JL, Jensen MB, Chacon MR, Sattin JA, Prabhakaran V.

Ann Clin Transl Neurol. 2015 Feb;2(2):185-95. doi: 10.1002/acn3.165. Epub 2015 Jan 15.


Usage of fMRI for pre-surgical planning in brain tumor and vascular lesion patients: task and statistical threshold effects on language lateralization.

Nadkarni TN, Andreoli MJ, Nair VA, Yin P, Young BM, Kundu B, Pankratz J, Radtke A, Holdsworth R, Kuo JS, Field AS, Baskaya MK, Moritz CH, Meyerand ME, Prabhakaran V.

Neuroimage Clin. 2014 Dec 24;7:415-23. doi: 10.1016/j.nicl.2014.12.014. eCollection 2015.


Alteration of NCoR corepressor splicing in mice causes increased body weight and hepatosteatosis without glucose intolerance.

Goodson ML, Young BM, Snyder CA, Schroeder AC, Privalsky ML.

Mol Cell Biol. 2014 Nov 15;34(22):4104-14. doi: 10.1128/MCB.00554-14. Epub 2014 Sep 2.


Characterizing relationships of DTI, fMRI, and motor recovery in stroke rehabilitation utilizing brain-computer interface technology.

Song J, Young BM, Nigogosyan Z, Walton LM, Nair VA, Grogan SW, Tyler ME, Farrar-Edwards D, Caldera KE, Sattin JA, Williams JC, Prabhakaran V.

Front Neuroeng. 2014 Jul 29;7:31. doi: 10.3389/fneng.2014.00031. eCollection 2014.


Changes in functional brain organization and behavioral correlations after rehabilitative therapy using a brain-computer interface.

Young BM, Nigogosyan Z, Walton LM, Song J, Nair VA, Grogan SW, Tyler ME, Edwards DF, Caldera K, Sattin JA, Williams JC, Prabhakaran V.

Front Neuroeng. 2014 Jul 15;7:26. doi: 10.3389/fneng.2014.00026. eCollection 2014.


Changes in functional connectivity correlate with behavioral gains in stroke patients after therapy using a brain-computer interface device.

Young BM, Nigogosyan Z, Remsik A, Walton LM, Song J, Nair VA, Grogan SW, Tyler ME, Edwards DF, Caldera K, Sattin JA, Williams JC, Prabhakaran V.

Front Neuroeng. 2014 Jul 8;7:25. doi: 10.3389/fneng.2014.00025. eCollection 2014.


CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement.

Amelio AL, Fallahi M, Schaub FX, Zhang M, Lawani MB, Alperstein AS, Southern MR, Young BM, Wu L, Zajac-Kaye M, Kaye FJ, Cleveland JL, Conkright MD.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3260-8. doi: 10.1073/pnas.1319176111. Epub 2014 Jul 28.


BCI-FES: could a new rehabilitation device hold fresh promise for stroke patients?

Young BM, Williams J, Prabhakaran V.

Expert Rev Med Devices. 2014 Nov;11(6):537-9. doi: 10.1586/17434440.2014.941811. Epub 2014 Jul 25.


Case report: post-stroke interventional BCI rehabilitation in an individual with preexisting sensorineural disability.

Young BM, Nigogosyan Z, Nair VA, Walton LM, Song J, Tyler ME, Edwards DF, Caldera K, Sattin JA, Williams JC, Prabhakaran V.

Front Neuroeng. 2014 Jun 24;7:18. doi: 10.3389/fneng.2014.00018. eCollection 2014.


Clinical validation and applications for CT-based atlas for contouring the lower cranial nerves for head and neck cancer radiation therapy.

Mourad WF, Young BM, Young R, Blakaj DM, Ohri N, Shourbaji RA, Manolidis S, Gámez M, Kumar M, Khorsandi A, Khan MA, Shasha D, Blakaj A, Glanzman J, Garg MK, Hu KS, Kalnicki S, Harrison LB.

Oral Oncol. 2013 Sep;49(9):956-963. doi: 10.1016/j.oraloncology.2013.03.449. Epub 2013 Apr 25.


Characterizing the relationship between functional MRI-derived measures and clinical outcomes in patients with vascular lesions.

Gallagher TA, Nair VA, Regner MF, Young BM, Radtke A, Pankratz J, Holdsworth RL, Baniulis D, Kornder NK, Voss J, Austin BP, Moritz C, Meyerand EM, Prabhakaran V.

Neurosurg Focus. 2013 Apr;34(4):E8. doi: 10.3171/2013.2.FOCUS12417.


Comparison of four probabilistic models (CARES(®), Calendex™, ConsExpo, and SHEDS) to estimate aggregate residential exposures to pesticides.

Young BM, Tulve NS, Egeghy PP, Driver JH, Zartarian VG, Johnston JE, Delmaar CJ, Evans JJ, Smith LA, Glen G, Lunchick C, Ross JH, Xue J, Barnekow DE.

J Expo Sci Environ Epidemiol. 2012 Sep;22(5):522-32. doi: 10.1038/jes.2012.54. Epub 2012 Jul 11.


On freedom.

Young BM.

CMAJ. 2011 Nov 8;183(16):1886-7. doi: 10.1503/cmaj.110562. No abstract available.


A mechanism for pituitary-resistance to thyroid hormone (PRTH) syndrome: a loss in cooperative coactivator contacts by thyroid hormone receptor (TR)beta2.

Lee S, Young BM, Wan W, Chan IH, Privalsky ML.

Mol Endocrinol. 2011 Jul;25(7):1111-25. doi: 10.1210/me.2010-0448. Epub 2011 May 26.


Lost in more than just translation.

Young BM.

Ann Intern Med. 2011 Apr 5;154(7):502. doi: 10.7326/0003-4819-154-7-201104050-00010. No abstract available.


Structure-activity relationships of substituted 1-pyridyl-2-phenyl-1,2-ethanediones: potent, selective carboxylesterase inhibitors.

Young BM, Hyatt JL, Bouck DC, Chen T, Hanumesh P, Price J, Boyd VA, Potter PM, Webb TR.

J Med Chem. 2010 Dec 23;53(24):8709-15. doi: 10.1021/jm101101q. Epub 2010 Nov 24.


miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution.

Carraro G, El-Hashash A, Guidolin D, Tiozzo C, Turcatel G, Young BM, De Langhe SP, Bellusci S, Shi W, Parnigotto PP, Warburton D.

Dev Biol. 2009 Sep 15;333(2):238-50. doi: 10.1016/j.ydbio.2009.06.020. Epub 2009 Jun 25.


The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors.

Privalsky ML, Lee S, Hahm JB, Young BM, Fong RN, Chan IH.

J Biol Chem. 2009 Jul 17;284(29):19554-63. doi: 10.1074/jbc.M109.007542. Epub 2009 Jun 1.


Expression quantitative trait loci mapping identifies new genetic models of glutathione S-transferase variation.

Hayes KR, Young BM, Pletcher MT.

Drug Metab Dispos. 2009 Jun;37(6):1269-76. doi: 10.1124/dmd.109.026856. Epub 2009 Mar 26.


Cancer patterns in Inuit populations.

Young BM.

Lancet Oncol. 2008 Dec;9(12):1124. doi: 10.1016/S1470-2045(08)70295-X. No abstract available.


Chronic ethanol induces inhibition of antigen-specific CD8+ but not CD4+ immunodominant T cell responses following Listeria monocytogenes inoculation.

Gurung P, Young BM, Coleman RA, Wiechert S, Turner LE, Ray NB, Waldschmidt TJ, Legge KL, Cook RT.

J Leukoc Biol. 2009 Jan;85(1):34-43. doi: 10.1189/jlb.0208101. Epub 2008 Sep 26.


Effect of flagellar mutations on Yersinia enterocolitica biofilm formation.

Kim TJ, Young BM, Young GM.

Appl Environ Microbiol. 2008 Sep;74(17):5466-74. doi: 10.1128/AEM.00222-08. Epub 2008 Jul 7.

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