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Items: 24


Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.

Malekzadeh P, Yossef R, Cafri G, Paria BC, Lowery FJ, Jafferji M, Good ML, Sachs A, Copeland AR, Kim SP, Kivitz S, Parkhurst MR, Robbins PF, Ray S, Xi L, Raffeld M, Yu Z, Restifo NP, Somerville RPT, Rosenberg SA, Deniger DC.

Clin Cancer Res. 2020 Jan 29. doi: 10.1158/1078-0432.CCR-19-1874. [Epub ahead of print]


Recognition of human gastrointestinal cancer neoantigens by circulating PD-1+ lymphocytes.

Gros A, Tran E, Parkhurst MR, Ilyas S, Pasetto A, Groh EM, Robbins PF, Yossef R, Garcia-Garijo A, Fajardo CA, Prickett TD, Jia L, Gartner JJ, Ray S, Ngo L, Wunderllich JR, Yang JC, Rosenberg SA.

J Clin Invest. 2019 Nov 1;129(11):4992-5004. doi: 10.1172/JCI127967.


Inhibition of the NKp44-PCNA Immune Checkpoint Using a mAb to PCNA.

Kundu K, Ghosh S, Sarkar R, Edri A, Brusilovsky M, Gershoni-Yahalom O, Yossef R, Shemesh A, Soria JC, Lazar V, Joshua BZ, Campbell KS, Elkabets M, Porgador A.

Cancer Immunol Res. 2019 Jul;7(7):1120-1134. doi: 10.1158/2326-6066.CIR-19-0023. Epub 2019 Jun 4.


Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers.

Parkhurst MR, Robbins PF, Tran E, Prickett TD, Gartner JJ, Jia L, Ivey G, Li YF, El-Gamil M, Lalani A, Crystal JS, Sachs A, Groh E, Ray S, Ngo LT, Kivitz S, Pasetto A, Yossef R, Lowery FJ, Goff SL, Lo W, Cafri G, Deniger DC, Malekzadeh P, Ahmadzadeh M, Wunderlich JR, Somerville RPT, Rosenberg SA.

Cancer Discov. 2019 Aug;9(8):1022-1035. doi: 10.1158/2159-8290.CD-18-1494. Epub 2019 Jun 4.


Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients.

Cafri G, Yossef R, Pasetto A, Deniger DC, Lu YC, Parkhurst M, Gartner JJ, Jia L, Ray S, Ngo LT, Jafferji M, Sachs A, Prickett T, Robbins PF, Rosenberg SA.

Nat Commun. 2019 Jan 25;10(1):449. doi: 10.1038/s41467-019-08304-z.


Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy.

Yossef R, Tran E, Deniger DC, Gros A, Pasetto A, Parkhurst MR, Gartner JJ, Prickett TD, Cafri G, Robbins PF, Rosenberg SA.

JCI Insight. 2018 Oct 4;3(19). pii: 122467. doi: 10.1172/jci.insight.122467.


NKp44-Derived Peptide Binds Proliferating Cell Nuclear Antigen and Mediates Tumor Cell Death.

Shemesh A, Kundu K, Peleg R, Yossef R, Kaplanov I, Ghosh S, Khrapunsky Y, Gershoni-Yahalom O, Rabinski T, Cerwenka A, Atlas R, Porgador A.

Front Immunol. 2018 May 23;9:1114. doi: 10.3389/fimmu.2018.01114. eCollection 2018.


T-cell Responses to TP53 "Hotspot" Mutations and Unique Neoantigens Expressed by Human Ovarian Cancers.

Deniger DC, Pasetto A, Robbins PF, Gartner JJ, Prickett TD, Paria BC, Malekzadeh P, Jia L, Yossef R, Langhan MM, Wunderlich JR, Danforth DN, Somerville RPT, Rosenberg SA.

Clin Cancer Res. 2018 Nov 15;24(22):5562-5573. doi: 10.1158/1078-0432.CCR-18-0573. Epub 2018 May 31.


Expression of NKp46 Splice Variants in Nasal Lavage Following Respiratory Viral Infection: Domain 1-Negative Isoforms Predominate and Manifest Higher Activity.

Shemer-Avni Y, Kundu K, Shemesh A, Brusilovsky M, Yossef R, Meshesha M, Solomon-Alemayehu S, Levin S, Gershoni-Yahalom O, Campbell KS, Porgador A.

Front Immunol. 2017 Feb 15;8:161. doi: 10.3389/fimmu.2017.00161. eCollection 2017.


IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation.

Rider P, Carmi Y, Yossef R, Guttman O, Eini H, Azam T, Dinarello CA, Lewis EC.

J Immunol. 2015 Aug 15;195(4):1705-12. doi: 10.4049/jimmunol.1501168. Epub 2015 Jul 8.


Efficient peptide recovery from secreted recombinant MHC-I molecules expressed via mRNA transfection.

Lazarus D, Weinstein-Marom H, Fishman S, Yossef R, Zuri D, Barnea E, Admon A, Margalit A, Gross G.

Immunol Lett. 2015 May;165(1):32-8. doi: 10.1016/j.imlet.2015.03.008. Epub 2015 Apr 1.


Targeting natural killer cell reactivity by employing antibody to NKp46: implications for type 1 diabetes.

Yossef R, Gur C, Shemesh A, Guttman O, Hadad U, Nedvetzki S, Miletić A, Nalbandyan K, Cerwenka A, Jonjic S, Mandelboim O, Porgador A.

PLoS One. 2015 Feb 26;10(2):e0118936. doi: 10.1371/journal.pone.0118936. eCollection 2015.


Colorimetric polymer assay for the diagnosis of plasma lipids atherogenic quality in hypercholesterolemic patients.

Mann E, Kolusheva S, Yossef R, Porgador A, Aviram M, Jelinek R.

Mol Diagn Ther. 2015 Feb;19(1):35-43. doi: 10.1007/s40291-014-0127-y.


Regulation of natural cytotoxicity receptors by heparan sulfate proteoglycans in -cis: A lesson from NKp44.

Brusilovsky M, Radinsky O, Cohen L, Yossef R, Shemesh A, Braiman A, Mandelboim O, Campbell KS, Porgador A.

Eur J Immunol. 2015 Apr;45(4):1180-91. doi: 10.1002/eji.201445177. Epub 2015 Jan 21.


α1-Antitrypsin modifies general NK cell interactions with dendritic cells and specific interactions with islet β-cells in favor of protection from autoimmune diabetes.

Guttman O, Yossef R, Freixo-Lima G, Rider P, Porgador A, Lewis EC.

Immunology. 2014 Oct 13. doi: 10.1111/imm.12403. [Epub ahead of print]


Carbohydrate-mediated modulation of NK cell receptor function: structural and functional influences of heparan sulfate moieties expressed on NK cell surface.

Brusilovsky M, Radinsky O, Yossef R, Campbell KS, Porgador A.

Front Oncol. 2014 Jul 16;4:185. doi: 10.3389/fonc.2014.00185. eCollection 2014. Review. No abstract available.


A novel "reactomics" approach for cancer diagnostics.

Kolusheva S, Yossef R, Kugel A, Hanin-Avraham N, Cohen M, Rubin E, Porgador A.

Sensors (Basel). 2012;12(5):5572-85. doi: 10.3390/s120505572. Epub 2012 May 2.


Array-based disease diagnostics using lipid/polydiacetylene vesicles encapsulated in a sol-gel matrix.

Kolusheva S, Yossef R, Kugel A, Katz M, Volinsky R, Welt M, Hadad U, Drory V, Kliger M, Rubin E, Porgador A, Jelinek R.

Anal Chem. 2012 Jul 17;84(14):5925-31. doi: 10.1021/ac300449u. Epub 2012 Jul 6.


Dimerization of NKp46 receptor is essential for NKp46-mediated lysis: characterization of the dimerization site by epitope mapping.

Jaron-Mendelson M, Yossef R, Appel MY, Zilka A, Hadad U, Afergan F, Rosental B, Engel S, Nedvetzki S, Braiman A, Porgador A.

J Immunol. 2012 Jun 15;188(12):6165-74. doi: 10.4049/jimmunol.1102496. Epub 2012 May 21.


The effect of chemotherapy/radiotherapy on cancerous pattern recognition by NK cells.

Rosental B, Appel MY, Yossef R, Hadad U, Brusilovsky M, Porgador A.

Curr Med Chem. 2012;19(12):1780-91. Review.


Upregulation of MHC class I expression following dengue virus infection: the mechanism at the promoter level.

Yossef R, Rosental B, Appel MY, Hershkovitz O, Porgador A.

Expert Rev Anti Infect Ther. 2012 Mar;10(3):285-7. doi: 10.1586/eri.12.7.


Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44.

Rosental B, Brusilovsky M, Hadad U, Oz D, Appel MY, Afergan F, Yossef R, Rosenberg LA, Aharoni A, Cerwenka A, Campbell KS, Braiman A, Porgador A.

J Immunol. 2011 Dec 1;187(11):5693-702. doi: 10.4049/jimmunol.1102267. Epub 2011 Oct 21.


The natural cytotoxicity receptor 1 contribution to early clearance of Streptococcus pneumoniae and to natural killer-macrophage cross talk.

Elhaik-Goldman S, Kafka D, Yossef R, Hadad U, Elkabets M, Vallon-Eberhard A, Hulihel L, Jung S, Ghadially H, Braiman A, Apte RN, Mandelboim O, Dagan R, Mizrachi-Nebenzahl Y, Porgador A.

PLoS One. 2011;6(8):e23472. doi: 10.1371/journal.pone.0023472. Epub 2011 Aug 22.


Serum apolipoproteins C-I and C-III are reduced in stomach cancer patients: results from MALDI-based peptidome and immuno-based clinical assays.

Cohen M, Yossef R, Erez T, Kugel A, Welt M, Karpasas MM, Bones J, Rudd PM, Taieb J, Boissin H, Harats D, Noy K, Tekoah Y, Lichtenstein RG, Rubin E, Porgador A.

PLoS One. 2011 Jan 18;6(1):e14540. doi: 10.1371/journal.pone.0014540.

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