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Items: 1 to 50 of 98

1.

Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation.

Gurumurthy CB, O'Brien AR, Quadros RM, Adams J Jr, Alcaide P, Ayabe S, Ballard J, Batra SK, Beauchamp MC, Becker KA, Bernas G, Brough D, Carrillo-Salinas F, Chan W, Chen H, Dawson R, DeMambro V, D'Hont J, Dibb KM, Eudy JD, Gan L, Gao J, Gonzales A, Guntur AR, Guo H, Harms DW, Harrington A, Hentges KE, Humphreys N, Imai S, Ishii H, Iwama M, Jonasch E, Karolak M, Keavney B, Khin NC, Konno M, Kotani Y, Kunihiro Y, Lakshmanan I, Larochelle C, Lawrence CB, Li L, Lindner V, Liu XD, Lopez-Castejon G, Loudon A, Lowe J, Jerome-Majewska LA, Matsusaka T, Miura H, Miyasaka Y, Morpurgo B, Motyl K, Nabeshima YI, Nakade K, Nakashiba T, Nakashima K, Obata Y, Ogiwara S, Ouellet M, Oxburgh L, Piltz S, Pinz I, Ponnusamy MP, Ray D, Redder RJ, Rosen CJ, Ross N, Ruhe MT, Ryzhova L, Salvador AM, Alam SS, Sedlacek R, Sharma K, Smith C, Staes K, Starrs L, Sugiyama F, Takahashi S, Tanaka T, Trafford AW, Uno Y, Vanhoutte L, Vanrockeghem F, Willis BJ, Wright CS, Yamauchi Y, Yi X, Yoshimi K, Zhang X, Zhang Y, Ohtsuka M, Das S, Garry DJ, Hochepied T, Thomas P, Parker-Thornburg J, Adamson AD, Yoshiki A, Schmouth JF, Golovko A, Thompson WR, Lloyd KCK, Wood JA, Cowan M, Mashimo T, Mizuno S, Zhu H, Kasparek P, Liaw L, Miano JM, Burgio G.

Genome Biol. 2019 Aug 26;20(1):171. doi: 10.1186/s13059-019-1776-2.

2.

Off- and on-target effects of genome editing in mouse embryos.

Ayabe S, Nakashima K, Yoshiki A.

J Reprod Dev. 2019 Feb 8;65(1):1-5. doi: 10.1262/jrd.2018-128. Epub 2018 Dec 6.

3.

Macrophage-Associated Gelatinase Degrades Basement Membrane at the Optic Fissure Margins During Normal Ocular Development in Mice.

Tsuji N, Matsuura T, Narama I, Yoshiki A, Ozaki K.

Invest Ophthalmol Vis Sci. 2018 Mar 1;59(3):1368-1373. doi: 10.1167/iovs.17-21841.

PMID:
29625460
4.

Corrigendum: High-throughput discovery of novel developmental phenotypes.

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie Helmut Fuchs SM, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Nutter SNLMJ, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium, Wurst W, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SDM, Adams DJ, Lloyd KCK, McKerlie C, Beaudet AL, Murray MBSA.

Nature. 2017 Nov 16;551(7680):398. doi: 10.1038/nature24643. Epub 2017 Nov 8.

5.

Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories.

Roy DS, Kitamura T, Okuyama T, Ogawa SK, Sun C, Obata Y, Yoshiki A, Tonegawa S.

Cell. 2017 Aug 24;170(5):1000-1012.e19. doi: 10.1016/j.cell.2017.07.013. Epub 2017 Aug 17.

6.

Characterization of novel dystonia musculorum mutant mice: Implications for central nervous system abnormality.

Horie M, Mekada K, Sano H, Kikkawa Y, Chiken S, Someya T, Saito K, Hossain MI, Nameta M, Abe K, Sakimura K, Ono K, Nambu A, Yoshiki A, Takebayashi H.

Neurobiol Dis. 2016 Dec;96:271-283. doi: 10.1016/j.nbd.2016.09.016. Epub 2016 Sep 28.

PMID:
27693510
7.

High-throughput discovery of novel developmental phenotypes.

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium; Jackson Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA.

Nature. 2016 Sep 22;537(7621):508-514. doi: 10.1038/nature19356. Epub 2016 Sep 14. Erratum in: Nature. 2017 Nov 16;551(7680):398.

8.

Germline recombination in a novel Cre transgenic line, Prl3b1-Cre mouse.

Al-Soudy AS, Nakanishi T, Mizuno S, Hasegawa Y, Shawki HH, Katoh MC, Basha WA, Ibrahim AE, El-Shemy HA, Iseki H, Yoshiki A, Hiromori Y, Nagase H, Takahashi S, Oishi H, Sugiyama F.

Genesis. 2016 Jul;54(7):389-97. doi: 10.1002/dvg.22944. Epub 2016 May 13.

PMID:
27124574
9.

Generation of CRISPR/Cas9-mediated bicistronic knock-in ins1-cre driver mice.

Hasegawa Y, Hoshino Y, Ibrahim AE, Kato K, Daitoku Y, Tanimoto Y, Ikeda Y, Oishi H, Takahashi S, Yoshiki A, Yagami K, Iseki H, Mizuno S, Sugiyama F.

Exp Anim. 2016 Jul 29;65(3):319-27. doi: 10.1538/expanim.16-0016. Epub 2016 Apr 7.

10.

NIG_MoG: a mouse genome navigator for exploring intersubspecific genetic polymorphisms.

Takada T, Yoshiki A, Obata Y, Yamazaki Y, Shiroishi T.

Mamm Genome. 2015 Aug;26(7-8):331-7. doi: 10.1007/s00335-015-9569-8. Epub 2015 May 27.

PMID:
26013919
11.

A simple and robust method for establishing homogeneous mouse epiblast stem cell lines by wnt inhibition.

Sugimoto M, Kondo M, Koga Y, Shiura H, Ikeda R, Hirose M, Ogura A, Murakami A, Yoshiki A, Chuva de Sousa Lopes SM, Abe K.

Stem Cell Reports. 2015 Apr 14;4(4):744-57. doi: 10.1016/j.stemcr.2015.02.014. Epub 2015 Mar 26.

12.

Effects of background mutations and single nucleotide polymorphisms (SNPs) on the Disc1 L100P behavioral phenotype associated with schizophrenia in mice.

Arime Y, Fukumura R, Miura I, Mekada K, Yoshiki A, Wakana S, Gondo Y, Akiyama K.

Behav Brain Funct. 2014 Dec 8;10:45. doi: 10.1186/1744-9081-10-45.

13.

Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus.

Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.

PLoS One. 2014 Dec 3;9(12):e114305. doi: 10.1371/journal.pone.0114305. eCollection 2014.

14.

Development of SNP markers for C57BL/6N-derived mouse inbred strains.

Mekada K, Hirose M, Murakami A, Yoshiki A.

Exp Anim. 2015;64(1):91-100. doi: 10.1538/expanim.14-0061. Epub 2014 Oct 23.

15.

Repeated encephalopathy and hemicerebral atrophy in a patient with familial hemiplegic migraine type 1.

Tashiro Y, Yamazaki T, Nagamine S, Mizuno Y, Yoshiki A, Okamoto K.

Intern Med. 2014;53(19):2245-50.

16.

Generation and characterization of Ins1-cre-driver C57BL/6N for exclusive pancreatic beta cell-specific Cre-loxP recombination.

Hasegawa Y, Daitoku Y, Mizuno S, Tanimoto Y, Mizuno-Iijima S, Matsuo M, Kajiwara N, Ema M, Oishi H, Miwa Y, Mekada K, Yoshiki A, Takahashi S, Sugiyama F, Yagami K.

Exp Anim. 2014;63(2):183-91.

17.

Island cells control temporal association memory.

Kitamura T, Pignatelli M, Suh J, Kohara K, Yoshiki A, Abe K, Tonegawa S.

Science. 2014 Feb 21;343(6173):896-901. doi: 10.1126/science.1244634. Epub 2014 Jan 23.

18.

Novel ROSA26 Cre-reporter knock-in C57BL/6N mice exhibiting green emission before and red emission after Cre-mediated recombination.

Hasegawa Y, Daitoku Y, Sekiguchi K, Tanimoto Y, Mizuno-Iijima S, Mizuno S, Kajiwara N, Ema M, Miwa Y, Mekada K, Yoshiki A, Takahashi S, Sugiyama F, Yagami K.

Exp Anim. 2013;62(4):295-304.

19.

Understanding the X chromosome inactivation cycle in mice: a comprehensive view provided by nuclear transfer.

Oikawa M, Inoue K, Shiura H, Matoba S, Kamimura S, Hirose M, Mekada K, Yoshiki A, Tanaka S, Abe K, Ishino F, Ogura A.

Epigenetics. 2014 Feb;9(2):204-11. doi: 10.4161/epi.26939. Epub 2013 Oct 29.

20.

High osmolality vitrification: a new method for the simple and temperature-permissive cryopreservation of mouse embryos.

Mochida K, Hasegawa A, Li MW, Fray MD, Kito S, Vallelunga JM, Lloyd KC, Yoshiki A, Obata Y, Ogura A.

PLoS One. 2013;8(1):e49316. doi: 10.1371/journal.pone.0049316. Epub 2013 Jan 16.

21.

High resolution intravital imaging of subcellular structures of mouse abdominal organs using a microstage device.

Cao L, Kobayakawa S, Yoshiki A, Abe K.

PLoS One. 2012;7(3):e33876. doi: 10.1371/journal.pone.0033876. Epub 2012 Mar 27.

22.

Cryopreservation of mouse embryos by ethylene glycol-based vitrification.

Mochida K, Hasegawa A, Taguma K, Yoshiki A, Ogura A.

J Vis Exp. 2011 Nov 18;(57). pii: 3155. doi: 10.3791/3155.

23.

Kbus/Idr, a mutant mouse strain with skeletal abnormalities and hypophosphatemia: identification as an allele of 'Hyp'.

Moriyama K, Hanai A, Mekada K, Yoshiki A, Ogiwara K, Kimura A, Takahashi T.

J Biomed Sci. 2011 Aug 20;18:60. doi: 10.1186/1423-0127-18-60.

24.

The RIKEN integrated database of mammals.

Masuya H, Makita Y, Kobayashi N, Nishikata K, Yoshida Y, Mochizuki Y, Doi K, Takatsuki T, Waki K, Tanaka N, Ishii M, Matsushima A, Takahashi S, Hijikata A, Kozaki K, Furuichi T, Kawaji H, Wakana S, Nakamura Y, Yoshiki A, Murata T, Fukami-Kobayashi K, Mohan S, Ohara O, Hayashizaki Y, Mizoguchi R, Obata Y, Toyoda T.

Nucleic Acids Res. 2011 Jan;39(Database issue):D861-70. doi: 10.1093/nar/gkq1078. Epub 2010 Nov 13.

25.

Suppression of cell-cycle progression by Jun dimerization protein-2 (JDP2) involves downregulation of cyclin-A2.

Pan J, Nakade K, Huang YC, Zhu ZW, Masuzaki S, Hasegawa H, Murata T, Yoshiki A, Yamaguchi N, Lee CH, Yang WC, Tsai EM, Obata Y, Yokoyama KK.

Oncogene. 2010 Nov 25;29(47):6245-56. doi: 10.1038/onc.2010.355. Epub 2010 Aug 30. Erratum in: Oncogene. 2011 Aug 18;30(33):3648.

26.

Distribution of the C1473G polymorphism in tryptophan hydroxylase 2 gene in laboratory and wild mice.

Osipova DV, Kulikov AV, Mekada K, Yoshiki A, Moshkin MP, Kotenkova EV, Popova NK.

Genes Brain Behav. 2010 Jul;9(5):537-43. doi: 10.1111/j.1601-183X.2010.00586.x. Epub 2010 Apr 8.

27.

Genetic variation of melatonin productivity in laboratory mice under domestication.

Kasahara T, Abe K, Mekada K, Yoshiki A, Kato T.

Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6412-7. doi: 10.1073/pnas.0914399107. Epub 2010 Mar 22.

28.

Four-dimensional quantitative analysis of the gait of mutant mice using coarse-grained motion capture.

Oota S, Mekada K, Fujita Y, Humphries J, Fukami-Kobayashi K, Obata Y, Rowe T, Yoshiki A.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:5227-30. doi: 10.1109/IEMBS.2009.5334287.

PMID:
19964861
29.

NBRP databases: databases of biological resources in Japan.

Yamazaki Y, Akashi R, Banno Y, Endo T, Ezura H, Fukami-Kobayashi K, Inaba K, Isa T, Kamei K, Kasai F, Kobayashi M, Kurata N, Kusaba M, Matuzawa T, Mitani S, Nakamura T, Nakamura Y, Nakatsuji N, Naruse K, Niki H, Nitasaka E, Obata Y, Okamoto H, Okuma M, Sato K, Serikawa T, Shiroishi T, Sugawara H, Urushibara H, Yamamoto M, Yaoita Y, Yoshiki A, Kohara Y.

Nucleic Acids Res. 2010 Jan;38(Database issue):D26-32. doi: 10.1093/nar/gkp996. Epub 2009 Nov 24.

30.

Simultaneous detection of multiple transgenes for genetically-modified mouse strains.

Nakata H, Hashimoto T, Seki Y, Mekada K, Obata Y, Yoshiki A.

Exp Anim. 2009 Jul;58(4):437-42.

31.

Sex-reversed somatic cell cloning in the mouse.

Inoue K, Ogonuki N, Mekada K, Yoshiki A, Sado T, Ogura A.

J Reprod Dev. 2009 Oct;55(5):566-9. Epub 2009 Jul 14.

32.

Genetic differences among C57BL/6 substrains.

Mekada K, Abe K, Murakami A, Nakamura S, Nakata H, Moriwaki K, Obata Y, Yoshiki A.

Exp Anim. 2009 Apr;58(2):141-9.

33.

Unique inbred strain MSM/Ms established from the Japanese wild mouse.

Moriwaki K, Miyashita N, Mita A, Gotoh H, Tsuchiya K, Kato H, Mekada K, Noro C, Oota S, Yoshiki A, Obata Y, Yonekawa H, Shiroishi T.

Exp Anim. 2009 Apr;58(2):123-34.

34.

The mouse resources at the RIKEN BioResource center.

Yoshiki A, Ike F, Mekada K, Kitaura Y, Nakata H, Hiraiwa N, Mochida K, Ijuin M, Kadota M, Murakami A, Ogura A, Abe K, Moriwaki K, Obata Y.

Exp Anim. 2009 Apr;58(2):85-96. Review.

35.

A high-speed congenic strategy using first-wave male germ cells.

Ogonuki N, Inoue K, Hirose M, Miura I, Mochida K, Sato T, Mise N, Mekada K, Yoshiki A, Abe K, Kurihara H, Wakana S, Ogura A.

PLoS One. 2009;4(3):e4943. doi: 10.1371/journal.pone.0004943. Epub 2009 Mar 31.

36.

Efficient production of androgenetic embryos by round spermatid injection.

Miki H, Hirose M, Ogonuki N, Inoue K, Kezuka F, Honda A, Mekada K, Hanaki K, Iwafune H, Yoshiki A, Ishino F, Ogura A.

Genesis. 2009 Mar;47(3):155-60. doi: 10.1002/dvg.20451.

PMID:
19241381
37.

Establishment of germline-competent embryonic stem cell lines from the MSM/Ms strain.

Araki K, Takeda N, Yoshiki A, Obata Y, Nakagata N, Shiroishi T, Moriwaki K, Yamamura K.

Mamm Genome. 2009 Jan;20(1):14-20. doi: 10.1007/s00335-008-9160-7. Epub 2008 Dec 12.

PMID:
19082856
38.

Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation.

Toyo-oka K, Mori D, Yano Y, Shiota M, Iwao H, Goto H, Inagaki M, Hiraiwa N, Muramatsu M, Wynshaw-Boris A, Yoshiki A, Hirotsune S.

J Cell Biol. 2008 Mar 24;180(6):1133-47. doi: 10.1083/jcb.200705148. Epub 2008 Mar 17.

39.

Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament.

Tanaka S, Miura I, Yoshiki A, Kato Y, Yokoyama H, Shinogi A, Masuya H, Wakana S, Tamura M, Shiroishi T.

Genomics. 2007 Dec;90(6):703-11. Epub 2007 Oct 24.

40.

Lymphocytic choriomeningitis infection undetected by dirty-bedding sentinel monitoring and revealed after embryo transfer of an inbred strain derived from wild mice.

Ike F, Bourgade F, Ohsawa K, Sato H, Morikawa S, Saijo M, Kurane I, Takimoto K, Yamada YK, Jaubert J, Berard M, Nakata H, Hiraiwa N, Mekada K, Takakura A, Itoh T, Obata Y, Yoshiki A, Montagutelli X.

Comp Med. 2007 Jun;57(3):272-81.

PMID:
17605342
41.

JDP2 suppresses adipocyte differentiation by regulating histone acetylation.

Nakade K, Pan J, Yoshiki A, Ugai H, Kimura M, Liu B, Li H, Obata Y, Iwama M, Itohara S, Murata T, Yokoyama KK.

Cell Death Differ. 2007 Aug;14(8):1398-405. Epub 2007 Apr 20.

42.

Mouse phenome research: implications of genetic background.

Yoshiki A, Moriwaki K.

ILAR J. 2006;47(2):94-102. Review.

PMID:
16547366
43.

Fates of Cdh23/CDH23 with mutations affecting the cytoplasmic region.

Yonezawa S, Yoshizaki N, Kageyama T, Takahashi T, Sano M, Tokita Y, Masaki S, Inaguma Y, Hanai A, Sakurai N, Yoshiki A, Kusakabe M, Moriyama A, Nakayama A.

Hum Mutat. 2006 Jan;27(1):88-97.

PMID:
16281288
44.

Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration.

Toyo-Oka K, Sasaki S, Yano Y, Mori D, Kobayashi T, Toyoshima YY, Tokuoka SM, Ishii S, Shimizu T, Muramatsu M, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S.

Hum Mol Genet. 2005 Nov 1;14(21):3113-28. Epub 2005 Oct 3.

PMID:
16203747
45.

Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality.

Sasaki S, Mori D, Toyo-oka K, Chen A, Garrett-Beal L, Muramatsu M, Miyagawa S, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S.

Mol Cell Biol. 2005 Sep;25(17):7812-27.

46.

A new role for expressed pseudogenes as ncRNA: regulation of mRNA stability of its homologous coding gene.

Yano Y, Saito R, Yoshida N, Yoshiki A, Wynshaw-Boris A, Tomita M, Hirotsune S.

J Mol Med (Berl). 2004 Jul;82(7):414-22. Epub 2004 May 18.

PMID:
15148580
47.

Retinoic acid controls blood vessel formation by modulating endothelial and mural cell interaction via suppression of Tie2 signaling in vascular progenitor cells.

Suzuki Y, Komi Y, Ashino H, Yamashita J, Inoue J, Yoshiki A, Eichmann A, Amanuma H, Kojima S.

Blood. 2004 Jul 1;104(1):166-9. Epub 2004 Mar 16.

PMID:
15026310
48.

Identification of a new target molecule for a cascade therapy of polycystic kidney.

Yoshida N, Yano Y, Yoshiki A, Ueno M, Deguchi N, Hirotsune S.

Hum Cell. 2003 Jun;16(2):65-72.

PMID:
12968785
49.

Immunohistochemical evaluation of the muscularis mucosae in the ruminant forestomach.

Kitamura N, Yoshiki A, Sasaki M, Baltazar ET, Hondo E, Yamamoto Y, Agungpriyono S, Yamada J.

Anat Histol Embryol. 2003 Jun;32(3):175-8.

PMID:
12823104
50.

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.

Carninci P, Waki K, Shiraki T, Konno H, Shibata K, Itoh M, Aizawa K, Arakawa T, Ishii Y, Sasaki D, Bono H, Kondo S, Sugahara Y, Saito R, Osato N, Fukuda S, Sato K, Watahiki A, Hirozane-Kishikawa T, Nakamura M, Shibata Y, Yasunishi A, Kikuchi N, Yoshiki A, Kusakabe M, Gustincich S, Beisel K, Pavan W, Aidinis V, Nakagawara A, Held WA, Iwata H, Kono T, Nakauchi H, Lyons P, Wells C, Hume DA, Fagiolini M, Hensch TK, Brinkmeier M, Camper S, Hirota J, Mombaerts P, Muramatsu M, Okazaki Y, Kawai J, Hayashizaki Y.

Genome Res. 2003 Jun;13(6B):1273-89.

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