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[Analysis of brain histamine clearance using genetically engineered mice].

Yoshikawa T, Nakamura T, Yanai K.

Nihon Yakurigaku Zasshi. 2018;152(1):16-20. doi: 10.1254/fpj.152.16. Japanese.


Pentraxin3 increases in adult overweight and obese men after weight-loss by dietary modification with exercise training.

Zempo-Miyaki A, Kumagai H, Yoshikawa T, Myoenzono K, So R, Otsuki T, Tanaka K, Maeda S.

Appl Physiol Nutr Metab. 2018 Jul 10. doi: 10.1139/apnm-2018-0214. [Epub ahead of print]


Multicentre observational study of quality of life after surgical palliation of malignant gastric outlet obstruction for gastric cancer.

Fujitani K, Ando M, Sakamaki K, Terashima M, Kawabata R, Ito Y, Yoshikawa T, Kondo M, Kodera Y, Yoshida K.

BJS Open. 2018 Mar 15;1(6):165-174. doi: 10.1002/bjs5.26. eCollection 2017 Dec.


Effects of resistance training on arterial compliance and plasma endothelin-1 levels in healthy men.

Tagawa K, Ra SG, Kumagai H, Yoshikawa T, Yoshida Y, Takekoshi K, Sakai S, Miyauchi T, Maeda S.

Physiol Res. 2018 Jun 27;67(Supplementum 1):S155-S166.


Severe acyclovir-resistant herpes simplex virus 1 infection following cord blood transplantation.

Shigemura T, Nakazawa Y, Yoshikawa T, Fujii H, Yamada S, Saijo M, Okuyama R.

Int J Hematol. 2018 Jun 19. doi: 10.1007/s12185-018-2480-9. [Epub ahead of print] No abstract available.


Chromosomally integrated human herpesvirus 6 in the Japanese population.

Miura H, Kawamura Y, Hattori F, Kozawa K, Ihira M, Ohye T, Kurahashi H, Yoshikawa T.

J Med Virol. 2018 Jun 15. doi: 10.1002/jmv.25244. [Epub ahead of print]


Incidence of overwork-related mental disorders and suicide in Japan.

Yamauchi T, Sasaki T, Yoshikawa T, Matsumoto S, Takahashi M.

Occup Med (Lond). 2018 Jun 12. doi: 10.1093/occmed/kqy080. [Epub ahead of print]


Betaherpesvirus Complications and Management During Hematopoietic Stem Cell Transplantation.

Yoshikawa T.

Adv Exp Med Biol. 2018;1045:251-270. doi: 10.1007/978-981-10-7230-7_12.


Relationships between serum free fatty acid and pulse pressure amplification in overweight/obese men: insights from exercise training and dietary modification.

Yoshikawa T, Zempo-Miyaki A, Kumagai H, Myoenzono K, So R, Tsujimoto T, Tanaka K, Maeda S.

J Clin Biochem Nutr. 2018 May;62(3):254-258. doi: 10.3164/jcbn.17-103. Epub 2018 Mar 30.


[Adjuvant chemotherapy for gastric cancer].

Yoshikawa T.

Nihon Shokakibyo Gakkai Zasshi. 2018;115(6):507-513. doi: 10.11405/nisshoshi.115.507. Japanese. No abstract available.


R-THP-COP versus R-CHOP in patients younger than 70 years with untreated diffuse large B cell lymphoma: A randomized, open-label, noninferiority phase 3 trial.

Hara T, Yoshikawa T, Goto H, Sawada M, Yamada T, Fukuno K, Kasahara S, Shibata Y, Matsumoto T, Mabuchi R, Nakamura N, Nakamura H, Ninomiya S, Kitagawa J, Kanemura N, Nannya Y, Katsumura N, Takahashi T, Kito Y, Takami T, Miyazaki T, Takeuchi T, Shimizu M, Tsurumi H.

Hematol Oncol. 2018 Jun 8. doi: 10.1002/hon.2524. [Epub ahead of print]


Clinical course of human herpesvirus 6 infection in pediatric living donor liver transplantation.

Yasui T, Suzuki T, Yoshikawa T, Yatsuya H, Kawamura Y, Miura H, Hara F, Watanabe S, Uga N, Naoe A.

Pediatr Transplant. 2018 Jun 3:e13239. doi: 10.1111/petr.13239. [Epub ahead of print]


Histamine elicits glutamate release from cultured astrocytes.

Kárpáti A, Yoshikawa T, Nakamura T, Iida T, Matsuzawa T, Kitano H, Harada R, Yanai K.

J Pharmacol Sci. 2018 May 16. pii: S1347-8613(18)30083-5. doi: 10.1016/j.jphs.2018.05.002. [Epub ahead of print]


Whole-brain low-intensity pulsed ultrasound therapy markedly improves cognitive dysfunctions in mouse models of dementia - Crucial roles of endothelial nitric oxide synthase.

Eguchi K, Shindo T, Ito K, Ogata T, Kurosawa R, Kagaya Y, Monma Y, Ichijo S, Kasukabe S, Miyata S, Yoshikawa T, Yanai K, Taki H, Kanai H, Osumi N, Shimokawa H.

Brain Stimul. 2018 May 22. pii: S1935-861X(18)30159-1. doi: 10.1016/j.brs.2018.05.012. [Epub ahead of print]


Acyclovir Sensitivity and Neurovirulence of Herpes Simplex Virus Type 1 with Amino Acid Substitutions in the Viral Thymidine Kinase Gene, Which Were Detected in the Patients with Intractable Herpes Simplex Encephalitis Previously Reported.

Inagaki T, Satoh M, Fujii H, Yamada S, Shibamura M, Yoshikawa T, Harada S, Takeyama H, Saijo M.

Jpn J Infect Dis. 2018 May 31. doi: 10.7883/yoken.JJID.2018.176. [Epub ahead of print]


Validation of U.S. mortality prediction models for hospitalized heart failure in the United Kingdom and Japan.

Nagai T, Sundaram V, Shoaib A, Shiraishi Y, Kohsaka S, Rothnie KJ, Piper S, McDonagh TA, Hardman SMC, Goda A, Mizuno A, Sawano M, Rigby AS, Quint JK, Yoshikawa T, Clark AL, Anzai T, Cleland JGF.

Eur J Heart Fail. 2018 May 30. doi: 10.1002/ejhf.1210. [Epub ahead of print]


The clinical impact of Hangeshashinto (TJ-14) in the treatment of chemotherapy-induced oral mucositis in gastric cancer and colorectal cancer: Analyses of pooled data from two phase II randomized clinical trials (HANGESHA-G and HANGESHA-C).

Nishikawa K, Aoyama T, Oba MS, Yoshikawa T, Matsuda C, Munemoto Y, Takiguchi N, Tanabe K, Nagata N, Imano M, Oshiro M, Fukushima R, Kataoka M, Morita S, Tsuburaya A, Mishima H, Kono T, Sakamoto J.

J Cancer. 2018 Apr 19;9(10):1725-1730. doi: 10.7150/jca.24733. eCollection 2018.


Iris metastasis preceding diagnosis of gastric signet ring cell adenocarcinoma: a case report.

Yoshikawa T, Miyata K, Nakai T, Ohbayashi C, Kaneko M, Ogata N.

BMC Ophthalmol. 2018 May 25;18(1):125. doi: 10.1186/s12886-018-0795-1.


Questionnaire survey on adjuvant chemotherapy for elderly patients after gastrectomy indicates their vulnelabilities.

Tanahashi T, Yoshida K, Yamaguchi K, Okumura N, Takeno A, Fujitani K, Fukushima N, Takiguchi N, Nishida Y, Boku N, Yoshikawa T, Terashima M.

Gastric Cancer. 2018 May 24. doi: 10.1007/s10120-018-0834-x. [Epub ahead of print]


Late-phase human herpesvirus 6B reactivation in hematopoietic stem cell transplant recipients.

Miura H, Kawamura Y, Hattori F, Tanaka M, Kudo K, Ihira M, Yatsuya H, Takahashi Y, Kojima S, Yoshikawa T.

Transpl Infect Dis. 2018 May 24:e12916. doi: 10.1111/tid.12916. [Epub ahead of print]


Outcome of hospitalised heart failure in Japan and the United Kingdom stratified by plasma N-terminal pro-B-type natriuretic peptide.

Shiraishi Y, Nagai T, Kohsaka S, Goda A, Nagatomo Y, Mizuno A, Kohno T, Rigby A, Fukuda K, Yoshikawa T, Clark AL, Cleland JGF.

Clin Res Cardiol. 2018 May 21. doi: 10.1007/s00392-018-1283-6. [Epub ahead of print]


Case of progressive hyperopia due to flattening of cornea.

Hirai H, Maruoka S, Yoshikawa T, Ogata N.

Am J Ophthalmol Case Rep. 2018 Feb 24;10:169-171. doi: 10.1016/j.ajoc.2018.02.013. eCollection 2018 Jun.


Visceral adiposity and high adiponectin levels are associated with the prevalence of pancreatic cystic lesions.

Mizuno S, Nakai Y, Isayama H, Yoshikawa T, Saito K, Takahara N, Kogure H, Tada M, Hayashi N, Koike K.

Int J Obes (Lond). 2018 May 17. doi: 10.1038/s41366-018-0083-4. [Epub ahead of print]


Characterization of a G10P[14] rotavirus strain from a diarrheic child in Thailand: Evidence for bovine-to-human zoonotic transmission.

Tacharoenmuang R, Komoto S, Guntapong R, Ide T, Singchai P, Upachai S, Fukuda S, Yoshida Y, Murata T, Yoshikawa T, Ruchusatsawat K, Motomura K, Takeda N, Sangkitporn S, Taniguchi K.

Infect Genet Evol. 2018 May 15;63:43-57. doi: 10.1016/j.meegid.2018.05.009. [Epub ahead of print]


The Negative Survival Impact of Infectious Complications After Surgery is Canceled Out by the Response of Neoadjuvant Chemotherapy in Patients with Esophageal Cancer.

Kano K, Aoyama T, Yoshikawa T, Maezawa Y, Nakajima T, Hayashi T, Yamada T, Sato T, Oshima T, Rino Y, Masuda M, Cho H, Ogata T.

Ann Surg Oncol. 2018 Jul;25(7):2034-2043. doi: 10.1245/s10434-018-6504-8. Epub 2018 May 10.


Changes in bone metabolism after gastric cancer surgery in male patients: a prospective observational study.

Atsumi Y, Rino Y, Wada H, Kitani Y, Ozawa Y, Aoyama T, Oshima T, Yukawa N, Yoshikawa T, Masuda M.

Gastric Cancer. 2018 May 10. doi: 10.1007/s10120-018-0835-9. [Epub ahead of print]


Chemical compound-based direct reprogramming for future clinical applications.

Takeda Y, Harada Y, Yoshikawa T, Dai P.

Biosci Rep. 2018 May 8;38(3). pii: BSR20171650. doi: 10.1042/BSR20171650. Print 2018 Jun 29. Review.


Sexual Function Is an Indicator of Central Arterial Stiffness and Arterial Stiffness Gradient in Japanese Adult Men.

Kumagai H, Yoshikawa T, Myoenzono K, Kosaki K, Akazawa N, Asako ZM, Tsujimoto T, Kidokoro T, Tanaka K, Maeda S.

J Am Heart Assoc. 2018 May 5;7(10). pii: e007964. doi: 10.1161/JAHA.117.007964.


Contribution of induced pluripotent stem cell technologies to the understanding of cellular phenotypes in schizophrenia.

Balan S, Toyoshima M, Yoshikawa T.

Neurobiol Dis. 2018 May 3. pii: S0969-9961(18)30137-2. doi: 10.1016/j.nbd.2018.04.021. [Epub ahead of print] Review.


Clinical significance of secreted protein, acidic and cysteine-rich gene expression in patients with stage II/III gastric cancer following curative resection and adjuvant chemotherapy with S-1.

Suzuki Y, Oshima T, Yoshihara K, Sakamaki K, Aoyama T, Cho H, Shiozawa M, Yoshikawa T, Rino Y, Imada T, Masuda M.

Oncol Lett. 2018 May;15(5):7335-7343. doi: 10.3892/ol.2018.8248. Epub 2018 Mar 13.


A Novel System for Constructing a Recombinant Highly-Attenuated Vaccinia Virus Strain (LC16m8) Expressing Foreign Genes and Its Application for the Generation of LC16m8-Based Vaccines against Herpes Simplex Virus 2.

Omura N, Yoshikawa T, Fujii H, Shibamura M, Inagaki T, Kato H, Egawa K, Harada S, Yamada S, Takeyama H, Saijo M.

Jpn J Infect Dis. 2018 May 24;71(3):229-233. doi: 10.7883/yoken.JJID.2017.458. Epub 2018 Apr 27.


Bursectomy versus omentectomy alone for resectable gastric cancer (JCOG1001): a phase 3, open-label, randomised controlled trial.

Kurokawa Y, Doki Y, Mizusawa J, Terashima M, Katai H, Yoshikawa T, Kimura Y, Takiguchi S, Nishida Y, Fukushima N, Iwasaki Y, Kaji M, Hirao M, Katayama H, Sasako M.

Lancet Gastroenterol Hepatol. 2018 Jul;3(7):460-468. doi: 10.1016/S2468-1253(18)30090-6. Epub 2018 Apr 28.


Lactotripeptide ingestion increases cerebral blood flow velocity in middle-aged and older adults.

Akazawa N, Hamasaki A, Tanahashi K, Kosaki K, Yoshikawa T, Myoenzono K, Maeda S.

Nutr Res. 2018 May;53:61-66. doi: 10.1016/j.nutres.2018.03.009. Epub 2018 Mar 23.


Safety and efficacy of pasireotide in dumping syndrome-results from a phase 2, multicentre study.

Tack J, Aberle J, Arts J, Laville M, Oppert JM, Bender G, Bhoyrul S, McLaughlin T, Yoshikawa T, Vella A, Zhou J, Passos VQ, O'Connell P, Van Beek AP.

Aliment Pharmacol Ther. 2018 Jun;47(12):1661-1672. doi: 10.1111/apt.14664. Epub 2018 Apr 25.


A Pathological Study Using 2014 WHO Criteria Reveals Poor Prognosis of Grade 3 Ovarian Endometrioid Carcinomas.

Soyama H, Miyamoto M, Takano M, Iwahashi H, Kato K, Sakamoto T, Kuwahara M, Ishibashi H, Matuura H, Yoshikawa T, Aoyama T, Tsuda H, Furuya K.

In Vivo. 2018 May-Jun;32(3):597-602.


Diurnal Variation of Melatonin Concentration in the Cerebrospinal Fluid of Unanesthetized Microminipig.

Abe M, Kawaguchi H, Miura N, Akioka K, Ushikai M, Oi S, Yukawa A, Yoshikawa T, Izumi H, Horiuchi M.

In Vivo. 2018 May-Jun;32(3):583-590.


Decreased serum pyridoxal levels in schizophrenia: meta-analysis and Mendelian randomization analysis.

Tomioka Y, Numata S, Kinoshita M, Umehara H, Watanabe SY, Nakataki M, Iwayama Y, Toyota T, Ikeda M, Yamamori H, Shimodera S, Tajima A, Hashimoto R, Iwata N, Yoshikawa T, Ohmori T.

J Psychiatry Neurosci. 2018 May;43(3):194-200.


Effect of the National Stress Check Program on mental health among workers in Japan: A 1-year retrospective cohort study.

Imamura K, Asai Y, Watanabe K, Tsutsumi A, Shimazu A, Inoue A, Hiro H, Odagiri Y, Yoshikawa T, Yoshikawa E, Kawakami N.

J Occup Health. 2018 Apr 18. doi: 10.1539/joh.2017-0314-OA. [Epub ahead of print]


Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.

Kanda K, Sakamoto J, Matsumoto Y, Ikuta K, Goto N, Morita Y, Ohno M, Nishi K, Eto K, Kimura Y, Nakanishi Y, Ikegami K, Yoshikawa T, Fukuda A, Kawada K, Sakai Y, Ito A, Yoshida M, Kimura T, Chiba T, Nishi E, Seno H.

JCI Insight. 2018 Apr 19;3(8). pii: 91316. doi: 10.1172/jci.insight.91316. [Epub ahead of print]


Generation of Recombinant Rotaviruses Expressing Fluorescent Proteins by Using an Optimized Reverse Genetics System.

Komoto S, Fukuda S, Ide T, Ito N, Sugiyama M, Yoshikawa T, Murata T, Taniguchi K.

J Virol. 2018 Jun 13;92(13). pii: e00588-18. doi: 10.1128/JVI.00588-18. Print 2018 Jul 1.


Performance Comparison Between 18F-FDG PET/CT Plus Brain MRI and Conventional Staging Plus Brain MRI in Staging of Small Cell Lung Carcinoma.

Kishida Y, Seki S, Yoshikawa T, Itoh T, Maniwa Y, Nishimura Y, Ohno Y.

AJR Am J Roentgenol. 2018 Jul;211(1):185-192. doi: 10.2214/AJR.17.18935. Epub 2018 Apr 18.


Infectious Diseases in Older Adults of Long-Term Care Facilities: Update on Approach to Diagnosis and Management.

Jump RLP, Crnich CJ, Mody L, Bradley SF, Nicolle LE, Yoshikawa TT.

J Am Geriatr Soc. 2018 Apr;66(4):789-803. doi: 10.1111/jgs.15248. Review.


[A Case of Unresectable Advanced Gastric Cancer Treated by Seven Courses of Chemotherapy with Docetaxel, Cisplatin, and S-1Followed by Conversion Surgery Achieved Five Year Relapse Free Survival].

Nakajima T, Cho H, Okubo Y, Kano K, Maezawa Y, Ikeda K, Yamada T, Ogata T, Yoshikawa T.

Gan To Kagaku Ryoho. 2018 Apr;45(4):755-757. Japanese.


Update of MR Imaging for Evaluation of Lung Cancer.

Ciliberto M, Kishida Y, Seki S, Yoshikawa T, Ohno Y.

Radiol Clin North Am. 2018 May;56(3):437-469. doi: 10.1016/j.rcl.2018.01.005. Review.


Heparan sulfate in pancreatic β-cells contributes to normal glucose homeostasis by regulating insulin secretion.

Matsuzawa T, Yoshikawa T, Iida T, Kárpáti A, Kitano H, Harada R, Nakamura T, Sugawara A, Yamaguchi Y, Yanai K.

Biochem Biophys Res Commun. 2018 May 15;499(3):688-695. doi: 10.1016/j.bbrc.2018.03.213. Epub 2018 Apr 3.


ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.

Kimura Y, Fukuda A, Ogawa S, Maruno T, Takada Y, Tsuda M, Hiramatsu Y, Araki O, Nagao M, Yoshikawa T, Ikuta K, Yoshioka T, Wang Z, Akiyama H, Wright CV, Takaori K, Uemoto S, Chiba T, Seno H.

Gastroenterology. 2018 Jul;155(1):194-209.e2. doi: 10.1053/j.gastro.2018.03.039. Epub 2018 Mar 29.


Early versus late readmission during the vulnerable phase following hospitalization for heart failure.

Kimura M, Kohno T, Yoshikawa T.

Eur J Heart Fail. 2018 Jul;20(7):1165-1166. doi: 10.1002/ejhf.1179. Epub 2018 Mar 30. No abstract available.


Clinical Characteristics, Management, and Outcomes of Japanese Patients Hospitalized for Heart Failure With Preserved Ejection Fraction - A Report From the Japanese Heart Failure Syndrome With Preserved Ejection Fraction (JASPER) Registry.

Nagai T, Yoshikawa T, Saito Y, Takeishi Y, Yamamoto K, Ogawa H, Anzai T; JASPER Investigators.

Circ J. 2018 May 25;82(6):1534-1545. doi: 10.1253/circj.CJ-18-0073. Epub 2018 Mar 23.


An increase in salivary flow with amitriptyline may indicate treatment resistance in burning mouth syndrome.

Kawasaki K, Nagamine T, Watanabe T, Suga T, Tu TTH, Sugawara S, Mikuzuki L, Miura A, Shinohara Y, Yoshikawa T, Takenoshita M, Toyofuku A.

Asia Pac Psychiatry. 2018 Mar 25:e12315. doi: 10.1111/appy.12315. [Epub ahead of print] No abstract available.


An Infected Aortic Aneurysm After Successful Treatment of Nontyphoidal Salmonella Gastroenteritis.

Yoshikawa T, Ohana M, Fukuda A.

Clin Gastroenterol Hepatol. 2018 Mar 21. pii: S1542-3565(17)31240-5. doi: 10.1016/j.cgh.2017.10.015. [Epub ahead of print] No abstract available.


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