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Items: 1 to 50 of 427

1.

Lactobacillus plantarum L-137 upregulates hyaluronic acid production in epidermal cells and fibroblasts in mice.

Nakai H, Hirose Y, Murosaki S, Yoshikai Y.

Microbiol Immunol. 2019 Jul 5. doi: 10.1111/1348-0421.12725. [Epub ahead of print]

PMID:
31273816
2.

Development of a new monoclonal antibody specific to mouse Vγ6 chain.

Hatano S, Tun X, Noguchi N, Yue D, Yamada H, Sun X, Matsumoto M, Yoshikai Y.

Life Sci Alliance. 2019 May 7;2(3). pii: e201900363. doi: 10.26508/lsa.201900363. Print 2019 Jun.

3.

CD30L/CD30 protects against psoriasiform skin inflammation by suppressing Th17-related cytokine production by Vγ4+ γδ T cells.

Yue D, You Y, Zhang X, Wang B, Wang X, Qi R, Yang F, Meng X, Yoshikai Y, Wang Y, Sun X.

J Autoimmun. 2019 Jul;101:70-85. doi: 10.1016/j.jaut.2019.04.009. Epub 2019 Apr 18.

4.

CD30 ligand deficiency accelerates glioma progression by promoting the formation of tumor immune microenvironment.

Duan J, Gao Y, Zhang X, Wang X, Wang B, Meng X, Yoshikai Y, Wang Y, Sun X.

Int Immunopharmacol. 2019 Jun;71:350-360. doi: 10.1016/j.intimp.2019.03.055. Epub 2019 Apr 2.

PMID:
30952099
5.

Viruses with masked pathogenicity and genetically susceptible hosts-How to discover potentially pathogenic viruses.

Nagafuchi S, Mine K, Takahashi H, Anzai K, Yoshikai Y.

J Med Virol. 2019 Aug;91(8):1365-1367. doi: 10.1002/jmv.25472. Epub 2019 Apr 9. No abstract available.

PMID:
30927455
6.

Fas/FasL signaling is critical for the survival of exhausted antigen-specific CD8+ T cells during tumor immune response.

Yajima T, Hoshino K, Muranushi R, Mogi A, Onozato R, Yamaki E, Kosaka T, Tanaka S, Shirabe K, Yoshikai Y, Kuwano H.

Mol Immunol. 2019 Mar;107:97-105. doi: 10.1016/j.molimm.2019.01.014. Epub 2019 Jan 30.

PMID:
30711908
7.

Cutting Edge: B Cells Expressing Cyclic Citrullinated Peptide-Specific Antigen Receptor Are Tolerized in Normal Conditions.

Yamada H, Ozawa T, Kishi H, Okada S, Nakashima Y, Muraguchi A, Yoshikai Y.

J Immunol. 2018 Dec 15;201(12):3492-3496. doi: 10.4049/jimmunol.1800826. Epub 2018 Nov 12.

PMID:
30420436
8.

Interleukin-21 Induces Short-Lived Effector CD8+ T Cells but Does Not Inhibit Their Exhaustion after Mycobacterium bovis BCG Infection in Mice.

Noguchi N, Nakamura R, Hatano S, Yamada H, Sun X, Ohara N, Yoshikai Y.

Infect Immun. 2018 Jul 23;86(8). pii: e00147-18. doi: 10.1128/IAI.00147-18. Print 2018 Aug.

9.

Association of Decreased Percentage of Vδ2+Vγ9+ γδ T Cells With Disease Severity in Multiple Sclerosis.

Maimaitijiang G, Shinoda K, Nakamura Y, Masaki K, Matsushita T, Isobe N, Yamasaki R, Yoshikai Y, Kira JI.

Front Immunol. 2018 Apr 10;9:748. doi: 10.3389/fimmu.2018.00748. eCollection 2018.

10.

Serum IgG ACPA-IgM RF immune complexes were detected in rheumatoid arthritis patients positive for IgM ACPA.

Haraguchi A, Yamada H, Kondo M, Okazaki K, Fukushi JI, Oyamada A, Yoshikai Y, Nakashima Y.

Clin Exp Rheumatol. 2018 Jul-Aug;36(4):612-618. Epub 2018 Feb 14.

PMID:
29465353
11.

Glucocorticoids Drive Diurnal Oscillations in T Cell Distribution and Responses by Inducing Interleukin-7 Receptor and CXCR4.

Shimba A, Cui G, Tani-Ichi S, Ogawa M, Abe S, Okazaki F, Kitano S, Miyachi H, Yamada H, Hara T, Yoshikai Y, Nagasawa T, Schütz G, Ikuta K.

Immunity. 2018 Feb 20;48(2):286-298.e6. doi: 10.1016/j.immuni.2018.01.004. Epub 2018 Jan 27.

12.

CD5-NK1.1+ γδ T Cells that Develop in a Bcl11b-Independent Manner Participate in Early Protection against Infection.

Hatano S, Murakami T, Noguchi N, Yamada H, Yoshikai Y.

Cell Rep. 2017 Oct 31;21(5):1191-1202. doi: 10.1016/j.celrep.2017.10.007.

13.

In vivo blockade of T cell development reveals alternative pathways for generation of intraepithelial lymphocytes in mice.

Mondoon S, Shibata K, Yoshikai Y.

Immunol Lett. 2017 Nov;191:40-46. doi: 10.1016/j.imlet.2017.09.008. Epub 2017 Sep 27.

PMID:
28958836
14.

Th1 is the predominant helper T cell subset that produces GM-CSF in the joint of rheumatoid arthritis.

Yamada H, Haraguchi A, Sakuraba K, Okazaki K, Fukushi JI, Mizu-Uchi H, Akasaki Y, Esaki Y, Kamura S, Fujimura K, Kondo M, Miyahara H, Nakashima Y, Yoshikai Y.

RMD Open. 2017 Jul 13;3(1):e000487. doi: 10.1136/rmdopen-2017-000487. eCollection 2017. No abstract available.

15.

Subtyping of Type 1 Diabetes as Classified by Anti-GAD Antibody, IgE Levels, and Tyrosine kinase 2 (TYK2) Promoter Variant in the Japanese.

Mine K, Hirakawa K, Kondo S, Minami M, Okada A, Tsutsu N, Yokogawa Y, Hibio Y, Kojima F, Fujimoto S, Kurisaki H, Anzai K, Yoshikai Y, Nagafuchi S; West Japan Pathogenesis of Diabetes Study Group.

EBioMedicine. 2017 Sep;23:46-51. doi: 10.1016/j.ebiom.2017.08.012. Epub 2017 Aug 12.

16.

C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection.

Toyonaga K, Torigoe S, Motomura Y, Kamichi T, Hayashi JM, Morita YS, Noguchi N, Chuma Y, Kiyohara H, Matsuo K, Tanaka H, Nakagawa Y, Sakuma T, Ohmuraya M, Yamamoto T, Umemura M, Matsuzaki G, Yoshikai Y, Yano I, Miyamoto T, Yamasaki S.

Immunity. 2016 Dec 20;45(6):1245-1257. doi: 10.1016/j.immuni.2016.10.012. Epub 2016 Nov 22.

17.

Two Types of Interleukin 17A-Producing γδ T Cells in Protection Against Pulmonary Infection With Klebsiella pneumoniae.

Murakami T, Hatano S, Yamada H, Iwakura Y, Yoshikai Y.

J Infect Dis. 2016 Dec 1;214(11):1752-1761. Epub 2016 Sep 20.

PMID:
27651419
18.

IL-21 inhibits IL-17A-producing γδ T-cell response after infection with Bacillus Calmette-Guérin via induction of apoptosis.

Huang Y, Matsumura Y, Hatano S, Noguchi N, Murakami T, Iwakura Y, Sun X, Ohara N, Yoshikai Y.

Innate Immun. 2016 Nov;22(8):588-597. doi: 10.1177/1753425916664125. Epub 2016 Sep 22.

PMID:
27554052
19.

IL-21/IL-21R signaling suppresses intestinal inflammation induced by DSS through regulation of Th responses in lamina propria in mice.

Wang Y, Jiang X, Zhu J, Dan Yue, Zhang X, Wang X, You Y, Wang B, Xu Y, Lu C, Sun X, Yoshikai Y.

Sci Rep. 2016 Aug 22;6:31881. doi: 10.1038/srep31881.

20.

Interleukin-21 signaling in B cells, but not in T cells, is indispensable for the development of collagen-induced arthritis in mice.

Sakuraba K, Oyamada A, Fujimura K, Spolski R, Iwamoto Y, Leonard WJ, Yoshikai Y, Yamada H.

Arthritis Res Ther. 2016 Aug 17;18:188. doi: 10.1186/s13075-016-1086-y.

21.

Antitumor activity of recombinant Bacille Calmette-Guérin secreting interleukin-15-Ag85B fusion protein against bladder cancer.

Takeuchi A, Eto M, Tatsugami K, Shiota M, Yamada H, Kamiryo Y, Dejima T, Kashiwagi E, Kiyoshima K, Inokuchi J, Takahashi R, Yokomizo A, Ohara N, Yoshikai Y.

Int Immunopharmacol. 2016 Jun;35:327-331. doi: 10.1016/j.intimp.2016.03.007. Epub 2016 Apr 16.

PMID:
27093372
22.

Recombinant Mycobacterium bovis bacillus Calmette-Guérin expressing Ag85B-IL-7 fusion protein enhances IL-17A-producing innate γδ T cells.

Hatano S, Tamura T, Umemura M, Matsuzaki G, Ohara N, Yoshikai Y.

Vaccine. 2016 May 11;34(22):2490-5. doi: 10.1016/j.vaccine.2016.03.096. Epub 2016 Apr 11.

PMID:
27079930
23.

Requirement of CD30 expression on CD4 T cells in the pathogenesis of experimental autoimmune encephalomyelitis.

Shinoda K, Sun X, Oyamada A, Yamada H, Kira J, Yoshikai Y.

J Neuroimmunol. 2016 Feb 15;291:39-45. doi: 10.1016/j.jneuroim.2015.12.005. Epub 2015 Dec 11.

PMID:
26857493
24.

An Enhancer of the IL-7 Receptor α-Chain Locus Controls IL-7 Receptor Expression and Maintenance of Peripheral T Cells.

Abe A, Tani-ichi S, Shitara S, Cui G, Yamada H, Miyachi H, Kitano S, Hara T, Abe R, Yoshikai Y, Ikuta K.

J Immunol. 2015 Oct 1;195(7):3129-38. doi: 10.4049/jimmunol.1302447. Epub 2015 Sep 2.

25.

IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2(+)Vγ6(+)γδ T cells.

Akitsu A, Ishigame H, Kakuta S, Chung SH, Ikeda S, Shimizu K, Kubo S, Liu Y, Umemura M, Matsuzaki G, Yoshikai Y, Saijo S, Iwakura Y.

Nat Commun. 2015 Jun 25;6:7464. doi: 10.1038/ncomms8464.

26.

Reduced Tyk2 gene expression in β-cells due to natural mutation determines susceptibility to virus-induced diabetes.

Izumi K, Mine K, Inoue Y, Teshima M, Ogawa S, Kai Y, Kurafuji T, Hirakawa K, Miyakawa D, Ikeda H, Inada A, Hara M, Yamada H, Akashi K, Niho Y, Ina K, Kobayashi T, Yoshikai Y, Anzai K, Yamashita T, Minagawa H, Fujimoto S, Kurisaki H, Shimoda K, Katsuta H, Nagafuchi S.

Nat Commun. 2015 Apr 7;6:6748. doi: 10.1038/ncomms7748.

27.

Scavenger receptor for lipoteichoic acid is involved in the potent ability of Lactobacillus plantarum strain L-137 to stimulate production of interleukin-12p40.

Hatano S, Hirose Y, Yamamoto Y, Murosaki S, Yoshikai Y.

Int Immunopharmacol. 2015 Apr;25(2):321-31. doi: 10.1016/j.intimp.2015.02.011. Epub 2015 Feb 16.

PMID:
25698554
28.

Brief report: successful in vitro culture of rheumatoid arthritis synovial tissue explants at the air-liquid interface.

Sakuraba K, Fujimura K, Nakashima Y, Okazaki K, Fukushi J, Ohishi M, Oyamada A, Esaki Y, Miyahara H, Iwamoto Y, Yoshikai Y, Yamada H.

Arthritis Rheumatol. 2015 Apr;67(4):887-92. doi: 10.1002/art.39019.

29.

CD30 ligand is a new therapeutic target for central nervous system autoimmunity.

Shinoda K, Sun X, Oyamada A, Yamada H, Muta H, Podack ER, Kira J, Yoshikai Y.

J Autoimmun. 2015 Feb;57:14-23. doi: 10.1016/j.jaut.2014.11.005. Epub 2014 Dec 19.

PMID:
25533628
30.

Renal cancer treatment with recipient lymphocyte infusion enhanced the antitumor effect of nonmyeloablative allogeneic stem cell transplantation.

Takeuchi A, Eto M, Tatsugami K, Yamada H, Yokomizo A, Shiota M, Itsumi M, Inokuchi J, Kiyoshima K, Dejima T, Imada K, Naito S, Yoshikai Y.

Transpl Immunol. 2015 Mar;32(2):131-9. doi: 10.1016/j.trim.2014.12.001. Epub 2014 Dec 16.

PMID:
25527449
31.

Dermal Vγ4(+) γδ T cells possess a migratory potency to the draining lymph nodes and modulate CD8(+) T-cell activity through TNF-α production.

Nakamizo S, Egawa G, Tomura M, Sakai S, Tsuchiya S, Kitoh A, Honda T, Otsuka A, Nakajima S, Dainichi T, Tanizaki H, Mitsuyama M, Sugimoto Y, Kawai K, Yoshikai Y, Miyachi Y, Kabashima K.

J Invest Dermatol. 2015 Apr;135(4):1007-1015. doi: 10.1038/jid.2014.516. Epub 2014 Dec 10.

32.

A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice.

Nakamura M, Shibata K, Hatano S, Sato T, Ohkawa Y, Yamada H, Ikuta K, Yoshikai Y.

J Immunol. 2015 Jan 1;194(1):243-51. doi: 10.4049/jimmunol.1401619. Epub 2014 Nov 26.

33.

Tyk2-dependent bystander activation of conventional and nonconventional Th1 cell subsets contributes to innate host defense against Listeria monocytogenes infection.

Hashiguchi T, Oyamada A, Sakuraba K, Shimoda K, Nakayama KI, Iwamoto Y, Yoshikai Y, Yamada H.

J Immunol. 2014 May 15;192(10):4739-47. doi: 10.4049/jimmunol.1303067. Epub 2014 Apr 11.

34.

SUMO-modification and elimination of the active DNA demethylation enzyme TDG in cultured human cells.

Moriyama T, Fujimitsu Y, Yoshikai Y, Sasano T, Yamada K, Murakami M, Urano T, Sugasawa K, Saitoh H.

Biochem Biophys Res Commun. 2014 May 9;447(3):419-24. doi: 10.1016/j.bbrc.2014.04.004. Epub 2014 Apr 12.

PMID:
24727457
35.

The SUMO-targeted ubiquitin ligase RNF4 localizes to etoposide-exposed mitotic chromosomes: implication for a novel DNA damage response during mitosis.

Saito M, Fujimitsu Y, Sasano T, Yoshikai Y, Ban-Ishihara R, Nariai Y, Urano T, Saitoh H.

Biochem Biophys Res Commun. 2014 Apr 25;447(1):83-8. doi: 10.1016/j.bbrc.2014.03.106. Epub 2014 Mar 30.

PMID:
24695317
36.

Oral administration of bovine milk from cows hyperimmunized with intestinal bacterin stimulates lamina propria T lymphocytes to produce Th1-biased cytokines in mice.

Wang Y, Lin L, Yin C, Othtani S, Aoyama K, Lu C, Sun X, Yoshikai Y.

Int J Mol Sci. 2014 Mar 28;15(4):5458-71. doi: 10.3390/ijms15045458.

37.

IFN-γ-producing and IL-17-producing γδ T cells differentiate at distinct developmental stages in murine fetal thymus.

Shibata K, Yamada H, Nakamura M, Hatano S, Katsuragi Y, Kominami R, Yoshikai Y.

J Immunol. 2014 Mar 1;192(5):2210-8. doi: 10.4049/jimmunol.1302145. Epub 2014 Jan 31.

38.

Type I interferon plays opposing roles in cytotoxicity and interferon-γ production by natural killer and CD8 T cells after influenza A virus infection in mice.

Arimori Y, Nakamura R, Yamada H, Shibata K, Maeda N, Kase T, Yoshikai Y.

J Innate Immun. 2014;6(4):456-66. doi: 10.1159/000356824. Epub 2014 Jan 10.

39.

Identification of independent susceptible and protective HLA alleles in Japanese autoimmune thyroid disease and their epistasis.

Ueda S, Oryoji D, Yamamoto K, Noh JY, Okamura K, Noda M, Kashiwase K, Kosuga Y, Sekiya K, Inoue K, Yamada H, Oyamada A, Nishimura Y, Yoshikai Y, Ito K, Sasazuki T.

J Clin Endocrinol Metab. 2014 Feb;99(2):E379-83. doi: 10.1210/jc.2013-2841. Epub 2013 Nov 27.

PMID:
24285682
40.

A C-type lectin receptor pathway is responsible for the pathogenesis of acute cyclophosphamide-induced cystitis in mice.

Dejima T, Shibata K, Yamada H, Takeuchi A, Hara H, Eto M, Naito S, Yoshikai Y.

Microbiol Immunol. 2013 Dec;57(12):833-41. doi: 10.1111/1348-0421.12100.

41.

CD30 is required for activation of a unique subset of interleukin-17A-producing γδ T cells in innate immunity against Mycobacterium bovis Bacillus Calmette-Guerin infection.

Guo Y, Sun X, Shibata K, Yamada H, Muta H, Podack ER, Yoshikai Y.

Infect Immun. 2013 Oct;81(10):3923-34. doi: 10.1128/IAI.00887-13. Epub 2013 Aug 5.

42.

Type I interferon limits influenza virus-induced acute lung injury by regulation of excessive inflammation in mice.

Arimori Y, Nakamura R, Yamada H, Shibata K, Maeda N, Kase T, Yoshikai Y.

Antiviral Res. 2013 Sep;99(3):230-7. doi: 10.1016/j.antiviral.2013.05.007. Epub 2013 May 28.

PMID:
23721943
43.

CD4 T cell-intrinsic IL-2 signaling differentially affects Th1 and Th17 development.

Fujimura K, Oyamada A, Iwamoto Y, Yoshikai Y, Yamada H.

J Leukoc Biol. 2013 Aug;94(2):271-9. doi: 10.1189/jlb.1112581. Epub 2013 May 28.

PMID:
23715742
44.

Positive selection of self-antigen-specific CD8+ T cells by hematopoietic cells.

Yamada H, Shibata K, Sakuraba K, Fujimura K, Yoshikai Y.

Eur J Immunol. 2013 Aug;43(8):2033-42. doi: 10.1002/eji.201242957. Epub 2013 May 22.

45.

C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor.

Miyake Y, Toyonaga K, Mori D, Kakuta S, Hoshino Y, Oyamada A, Yamada H, Ono K, Suyama M, Iwakura Y, Yoshikai Y, Yamasaki S.

Immunity. 2013 May 23;38(5):1050-62. doi: 10.1016/j.immuni.2013.03.010. Epub 2013 Apr 18.

46.

Fas-deficient fully allogeneic dendritic cells administered via an intratumoral injection route show efficient antitumor effects in murine models.

Okano S, Kondoh H, Toshima T, Nakagawara H, Yoshizumi T, Soejima Y, Shirabe K, Harada M, Yoshikai Y, Maehara Y.

Fukuoka Igaku Zasshi. 2013 Jan;104(1):15-26.

PMID:
23600321
47.

CD4 T cell-mediated masking effects of the immunogenicity of tumor-associated antigens are qualitatively and quantitatively different depending on the individual antigens.

Okano S, Matsumoto Y, Yoshiya S, Yamashita Y, Harimoto N, Ikegami T, Shirabe K, Harada M, Yoshikai Y, Maehara Y.

Fukuoka Igaku Zasshi. 2013 Jan;104(1):1-14.

PMID:
23600320
48.

CD30L/CD30 is critical for maintenance of IL-17A-producing γδ T cells bearing Vγ6 in mucosa-associated tissues in mice.

Sun X, Shibata K, Yamada H, Guo Y, Muta H, Podack ER, Yoshikai Y.

Mucosal Immunol. 2013 Nov;6(6):1191-201. doi: 10.1038/mi.2013.18. Epub 2013 Apr 3.

PMID:
23549449
49.

Role of RNF4 in the ubiquitination of Rta of Epstein-Barr virus.

Yang YC, Yoshikai Y, Hsu SW, Saitoh H, Chang LK.

J Biol Chem. 2013 May 3;288(18):12866-79. doi: 10.1074/jbc.M112.413393. Epub 2013 Mar 15.

50.

Naturally occurring PD-1+ memory phenotype CD8 T cells belong to nonconventional CD8 T cells and are cyclophosphamide-sensitive regulatory T cells.

Sakuraba K, Shibata K, Iwamoto Y, Yoshikai Y, Yamada H.

J Immunol. 2013 Feb 15;190(4):1560-6. doi: 10.4049/jimmunol.1202464. Epub 2013 Jan 9.

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