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Age-related changes in histone modification in rat gastrocnemius muscle.

Yoshihara T, Machida S, Tsuzuki T, Kakigi R, Chang SW, Sugiura T, Naito H.

Exp Gerontol. 2019 Jul 11;125:110658. doi: 10.1016/j.exger.2019.110658. [Epub ahead of print]


Muscle weakness and impaired motor coordination in Hcn1-deficient rats.

Nishitani A, Yoshihara T, Tanaka M, Kuwamura M, Asano M, Tsubota Y, Kuramoto T.

Exp Anim. 2019 Jul 9. doi: 10.1538/expanim.19-0067. [Epub ahead of print]


Periostin forms a functional complex with IgA in human serum.

Ono J, Takai M, Kamei A, Nunomura S, Nanri Y, Yoshihara T, Ohta S, Yasuda K, Conway SJ, Yokosaki Y, Izuhara K.

Allergol Int. 2019 Jul 1. pii: S1323-8930(19)30083-8. doi: 10.1016/j.alit.2019.05.014. [Epub ahead of print]


SCO-267, a GPR40 Full Agonist, Improves Glycemic and Body Weight Control in Rat Models of Diabetes and Obesity.

Ueno H, Ito R, Abe SI, Ookawara M, Miyashita H, Ogino H, Miyamoto Y, Yoshihara T, Kobayashi A, Tsujihata Y, Takeuchi K, Watanabe M, Yamada Y, Maekawa T, Nishigaki N, Moritoh Y.

J Pharmacol Exp Ther. 2019 Aug;370(2):172-181. doi: 10.1124/jpet.118.255885. Epub 2019 Jun 10.


Hes1 expression in mature neurons in the adult mouse brain is required for normal behaviors.

Matsuzaki T, Yoshihara T, Ohtsuka T, Kageyama R.

Sci Rep. 2019 Jun 3;9(1):8251. doi: 10.1038/s41598-019-44698-y.


Impact of different temperature stimuli on the expression of myosin heavy chain isoforms during recovery from bupivacaine-induced muscle injury in rats.

Shibaguchi T, Hoshi M, Yoshihara T, Naito H, Goto K, Yoshioka T, Sugiura T.

J Appl Physiol (1985). 2019 Jul 1;127(1):178-189. doi: 10.1152/japplphysiol.00930.2018. Epub 2019 May 23.


Exercise preconditioning attenuates hind limb unloading-induced gastrocnemius muscle atrophy possibly via the HDAC4/Gadd45 axis in old rats.

Yoshihara T, Tsuzuki T, Chang SW, Kakigi R, Sugiura T, Naito H.

Exp Gerontol. 2019 Jul 15;122:34-41. doi: 10.1016/j.exger.2019.04.010. Epub 2019 Apr 19.


Assessment of gamma radiation from a limited area of forest floor using a cumulative personal dosimeter.

Yoshihara T, Kurita K, Matsumura H, Yoschenko V, Kawachi N, Hashida SN, Konoplev A, Yoshida H.

J Environ Radioact. 2019 Aug;204:95-103. doi: 10.1016/j.jenvrad.2019.03.023. Epub 2019 Apr 13.


Fluorescence Quenching-based Assay for Measuring Golgi endo-α-Mannosidase.

Sano K, Kuribara T, Ishii N, Kuroiwa A, Yoshihara T, Tobita S, Totani K, Matsuo I.

Chem Asian J. 2019 Jun 3;14(11):1965-1969. doi: 10.1002/asia.201900240. Epub 2019 Apr 5.


Association between locomotive syndrome and blood parameters in Japanese middle-aged and elderly individuals: a cross-sectional study.

Yoshihara T, Ozaki H, Nakagata T, Natsume T, Kitada T, Ishihara Y, Sawada S, Ishibashi M, Kobayashi H, Machida S, Naito H.

BMC Musculoskelet Disord. 2019 Mar 14;20(1):104. doi: 10.1186/s12891-019-2480-9.


Growth Patterns of Neonates Treated with Thermal Control in Neutral Environment and Nutrition Regulation to Meet Basal Metabolism.

Kubota S, Zaitsu M, Yoshihara T.

Nutrients. 2019 Mar 11;11(3). pii: E592. doi: 10.3390/nu11030592.


A through year behavior of 137Cs in a Japanese flowering cherry tree in relation to that of potassium.

Yoshihara T, Yoschenko V, Watanabe K, Keitoku K.

J Environ Radioact. 2019 Jun;202:32-40. doi: 10.1016/j.jenvrad.2019.01.013. Epub 2019 Feb 15.


Influence of genetic polymorphisms and habitual caffeine intake on the changes in blood pressure, pulse rate, and calculation speed after caffeine intake: A prospective, double blind, randomized trial in healthy volunteers.

Yoshihara T, Zaitsu M, Shiraishi F, Arima H, Takahashi-Yanaga F, Arioka M, Kajioka S, Sasaguri T.

J Pharmacol Sci. 2019 Mar;139(3):209-214. doi: 10.1016/j.jphs.2019.01.006. Epub 2019 Feb 1.


Investigation of the Local Recurrence Rate after Colorectal Endoscopic Mucosal Resection: Is Incomplete Polyp Resection Really a Clinically Important Problem? Analysis of the Rationale for the "Resect and Discard" Strategy.

Arimoto J, Higurashi T, Chiba H, Misawa N, Yoshihara T, Kato T, Kanoshima K, Fuyuki A, Ohkubo H, Nonaka T, Sato T, Sakai E, Iida H, Goto T, Nakajima A.

Can J Gastroenterol Hepatol. 2019 Jan 8;2019:7243515. doi: 10.1155/2019/7243515. eCollection 2019.


Structure-efficiency relationship of photoinduced electron transfer-triggered nitric oxide releasers.

Ieda N, Oka Y, Yoshihara T, Tobita S, Sasamori T, Kawaguchi M, Nakagawa H.

Sci Rep. 2019 Feb 5;9(1):1430. doi: 10.1038/s41598-018-38252-5.


[A Case of Locally Advanced Gastric Cancer Treated with Chemoradiotherapy before Surgical Resection].

Yoshihara T, Hirota M, Nagase H, Noguchi K, Hamabe A, Tanida T, Tomimaru Y, Kawase T, Morita S, Imamura H, Dono K.

Gan To Kagaku Ryoho. 2018 Dec;45(13):2168-2170. Japanese.


Establishment of a Mouse Model of Atopic Dermatitis by Deleting Ikk2 in Dermal Fibroblasts.

Nunomura S, Ejiri N, Kitajima M, Nanri Y, Arima K, Mitamura Y, Yoshihara T, Fujii K, Takao K, Imura J, Fehling HJ, Izuhara K, Kitajima I.

J Invest Dermatol. 2019 Jun;139(6):1274-1283. doi: 10.1016/j.jid.2018.10.047. Epub 2019 Jan 19.


Mitochondrial dysfunction induces muscle atrophy during prolonged inactivity: A review of the causes and effects.

Hyatt H, Deminice R, Yoshihara T, Powers SK.

Arch Biochem Biophys. 2019 Feb 15;662:49-60. doi: 10.1016/ Epub 2018 Nov 16. Review.


Increased SOD2 in the diaphragm contributes to exercise-induced protection against ventilator-induced diaphragm dysfunction.

Morton AB, Smuder AJ, Wiggs MP, Hall SE, Ahn B, Hinkley JM, Ichinoseki-Sekine N, Huertas AM, Ozdemir M, Yoshihara T, Wawrzyniak NR, Powers SK.

Redox Biol. 2019 Jan;20:402-413. doi: 10.1016/j.redox.2018.10.005. Epub 2018 Oct 21.


Electromyostimulation with blood flow restriction enhances activation of mTOR and MAPK signaling pathways in rat gastrocnemius muscles.

Natsume T, Yoshihara T, Naito H.

Appl Physiol Nutr Metab. 2019 Jun;44(6):637-644. doi: 10.1139/apnm-2018-0384. Epub 2018 Nov 6.


Effect of a combination of astaxanthin supplementation, heat stress, and intermittent reloading on satellite cells during disuse muscle atrophy.

Yoshihara T, Sugiura T, Miyaji N, Yamamoto Y, Shibaguchi T, Kakigi R, Naito H, Goto K, Ohmori D, Yoshioka T.

J Zhejiang Univ Sci B. 2018 Nov.;19(11):844-852. doi: 10.1631/jzus.B1800076.


Body temperature elevation during exercise is essential for activating the Akt signaling pathway in the skeletal muscle of type 2 diabetic rats.

Tsuzuki T, Yoshihara T, Ichinoseki-Sekine N, Kakigi R, Takamine Y, Kobayashi H, Naito H.

PLoS One. 2018 Oct 10;13(10):e0205456. doi: 10.1371/journal.pone.0205456. eCollection 2018.


Sex differences in forkhead box O3a signaling response to hindlimb unloading in rat soleus muscle.

Yoshihara T, Natsume T, Tsuzuki T, Chang SW, Kakigi R, Sugiura T, Naito H.

J Physiol Sci. 2019 Mar;69(2):235-244. doi: 10.1007/s12576-018-0640-6. Epub 2018 Sep 27.


Effects of a progressive walking program on the risk of developing locomotive syndrome in elderly Japanese people: a single-arm trial.

Yoshihara T, Ozaki H, Nakagata T, Natsume T, Kitada T, Ishihara Y, Deng P, Osawa T, Ishibashi M, Ishijima M, Kobayashi H, Machida S, Naito H.

J Phys Ther Sci. 2018 Sep;30(9):1180-1186. doi: 10.1589/jpts.30.1180. Epub 2018 Sep 4.


Usefulness of Cardiac Magnetic Resonance in the Diagnosis of Löffler Endocarditis Secondary to Eosinophilic Granulomatosis with Polyangiitis.

Kurokawa K, Sai E, Hayashi E, Minowa K, Sugano K, Yoshihara T, Miyazaki T, Hiki M, Yokoyama T, Suzuki M, Miyauchi K.

Intern Med. 2019 Jan 15;58(2):239-242. doi: 10.2169/internalmedicine.1303-18. Epub 2018 Aug 24.


Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice.

Yoshihara T, Satake H, Nishie T, Okino N, Hatta T, Otani H, Naruse C, Suzuki H, Sugihara K, Kamimura E, Tokuda N, Furukawa K, Fururkawa K, Ito M, Asano M.

PLoS Genet. 2018 Aug 16;14(8):e1007545. doi: 10.1371/journal.pgen.1007545. eCollection 2018 Aug.


Hierarchical control of interleukin 13 (IL-13) signals in lung fibroblasts by STAT6 and SOX11.

Mitamura Y, Nunomura S, Nanri Y, Arima K, Yoshihara T, Komiya K, Fukuda S, Takatori H, Nakajima H, Furue M, Izuhara K.

J Biol Chem. 2018 Sep 21;293(38):14646-14658. doi: 10.1074/jbc.RA117.001364. Epub 2018 Aug 3.


Automated High-Throughput Flow Cytometry for High-Content Screening in Antibody Development.

Wang Y, Yoshihara T, King S, Le T, Leroy P, Zhao X, Chan CK, Yan ZH, Menon S.

SLAS Discov. 2018 Aug;23(7):656-666. doi: 10.1177/2472555218776607. Epub 2018 Jun 13.


Ir(iii) complex-based oxygen imaging of living cells and ocular fundus with a gated ICCD camera.

Akiyama H, Takahashi I, Shimoda Y, Mukai R, Yoshihara T, Tobita S.

Photochem Photobiol Sci. 2018 Jun 13;17(6):846-853. doi: 10.1039/c8pp00122g.


Perlecan, a heparan sulfate proteoglycan, regulates systemic metabolism with dynamic changes in adipose tissue and skeletal muscle.

Yamashita Y, Nakada S, Yoshihara T, Nara T, Furuya N, Miida T, Hattori N, Arikawa-Hirasawa E.

Sci Rep. 2018 May 17;8(1):7766. doi: 10.1038/s41598-018-25635-x.


Intravital phosphorescence lifetime imaging of the renal cortex accurately measures renal hypoxia.

Hirakawa Y, Mizukami K, Yoshihara T, Takahashi I, Khulan P, Honda T, Mimura I, Tanaka T, Tobita S, Nangaku M.

Kidney Int. 2018 Jun;93(6):1483-1489. doi: 10.1016/j.kint.2018.01.015. Epub 2018 Mar 30.


Usefulness of a novel device (Nelaton Attachment) for the two-fingers method during colorectal endoscopic submucosal dissection.

Yoshimoto T, Takihara H, Yoshihara T.

Dig Endosc. 2018 Jul;30(4):523. doi: 10.1111/den.13057. Epub 2018 Apr 15. No abstract available.


The IL-13/periostin/IL-24 pathway causes epidermal barrier dysfunction in allergic skin inflammation.

Mitamura Y, Nunomura S, Nanri Y, Ogawa M, Yoshihara T, Masuoka M, Tsuji G, Nakahara T, Hashimoto-Hachiya A, Conway SJ, Furue M, Izuhara K.

Allergy. 2018 Sep;73(9):1881-1891. doi: 10.1111/all.13437.


Effects of voluntary running exercise on bone histology in type 2 diabetic rats.

Takamine Y, Ichinoseki-Sekine N, Tsuzuki T, Yoshihara T, Naito H.

PLoS One. 2018 Feb 15;13(2):e0193068. doi: 10.1371/journal.pone.0193068. eCollection 2018.


Constitutive overexpression of periostin delays wound healing in mouse skin.

Nunomura S, Nanri Y, Ogawa M, Arima K, Mitamura Y, Yoshihara T, Hasuwa H, Conway SJ, Izuhara K.

Wound Repair Regen. 2018 Jan;26(1):6-15. doi: 10.1111/wrr.12616. Epub 2018 Mar 7.


Clinical practice guideline for Sjögren's syndrome 2017.

Sumida T, Azuma N, Moriyama M, Takahashi H, Asashima H, Honda F, Abe S, Ono Y, Hirota T, Hirata S, Tanaka Y, Shimizu T, Nakamura H, Kawakami A, Sano H, Ogawa Y, Tsubota K, Ryo K, Saito I, Tanaka A, Nakamura S, Takamura E, Tanaka M, Suzuki K, Takeuchi T, Yamakawa N, Mimori T, Ohta A, Nishiyama S, Yoshihara T, Suzuki Y, Kawano M, Tomiita M, Tsuboi H.

Mod Rheumatol. 2018 May;28(3):383-408. doi: 10.1080/14397595.2018.1438093. Epub 2018 Mar 13. Review.


[A Case of Small-Sized Acinar Cell Carcinoma of the Pancreas Resected by Laparoscopic Distal Pancreatectomy].

Yoshihara T, Tomimaru Y, Noguchi K, Nagase H, Hamabe A, Hirota M, Oshima K, Tanida T, Morita S, Imamura H, Iwazawa T, Akagi K, Dono K.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1964-1966. Japanese.


Minimally Invasive Endoscopic Approach to the Cervicothoracic Junction for Vertebral Osteomyelitis.

Morimoto T, Tsukamoto M, Yoshihara T, Sonohata M, Mawatari M.

Case Rep Orthop. 2017;2017:2495041. doi: 10.1155/2017/2495041. Epub 2017 Dec 11.


The Significance of Hypothiocyanite Production via the Pendrin/DUOX/Peroxidase Pathway in the Pathogenesis of Asthma.

Izuhara K, Suzuki S, Ogawa M, Nunomura S, Nanri Y, Mitamura Y, Yoshihara T.

Oxid Med Cell Longev. 2017;2017:1054801. doi: 10.1155/2017/1054801. Epub 2017 Nov 22. Review.


Hepatocellular carcinoma due to a baffle obstruction after the mustard operation: A case report.

Yoshihara T, Sakamori R, Furuta K, Shigekawa M, Yamada R, Kodama T, Hikita H, Yakushijin T, Tatsumi T, Sakata Y, Eguchi H, Sawa Y, Takehara T.

Hepatology. 2018 Jun;67(6):2471-2473. doi: 10.1002/hep.29758. Epub 2018 Apr 19. No abstract available.


Diagnostic and treatment effects of sialendoscopy for patients with swelling of the parotid gland when sialoliths are undetected with computed tomography.

Kondo N, Yoshihara T, Yamamura Y, Kusama K, Sakitani E, Seo Y, Tachikawa M, Kujirai K, Ono E, Maeda Y, Nojima T, Tamiya A, Sato E, Nonaka M.

Auris Nasus Larynx. 2018 Aug;45(4):880-884. doi: 10.1016/j.anl.2017.11.004. Epub 2017 Dec 6.


Continued Use of a Single Antiplatelet Agent Does Not Increase the Risk of Delayed Bleeding After Colorectal Endoscopic Submucosal Dissection.

Arimoto J, Higurashi T, Chiba H, Misawa N, Yoshihara T, Kato T, Kanoshima K, Fuyuki A, Ohkubo H, Goto S, Ishikawa Y, Tachikawa J, Ashikari K, Nonaka T, Taguri M, Kuriyama H, Atsukawa K, Nakajima A.

Dig Dis Sci. 2018 Jan;63(1):218-227. doi: 10.1007/s10620-017-4843-0. Epub 2017 Nov 24.


Basophils are increased and express increased levels of interleukin-4 in the parotid lesions of Kimura disease.

Nonaka M, Sakitani E, Ono E, Yamamura Y, Seo Y, Shibata N, Pawankar R, Yoshihara T.

Asia Pac Allergy. 2017 Oct;7(4):221-226. doi: 10.5415/apallergy.2017.7.4.221. Epub 2017 Oct 23.


Circadian rhythm of intracellular protein synthesis signaling in rat cardiac and skeletal muscles.

Chang SW, Yoshihara T, Machida S, Naito H.

Biochem Biophys Rep. 2016 Dec 23;9:153-158. doi: 10.1016/j.bbrep.2016.12.005. eCollection 2017 Mar.


Tissue Drug Concentrations of Anti-tumor Necrosis Factor Agents Are Associated with the Long-term Outcome of Patients with Crohn's Disease.

Yoshihara T, Shinzaki S, Kawai S, Fujii H, Iwatani S, Yamaguchi T, Araki M, Hiyama S, Inoue T, Hayashi Y, Watabe K, Iijima H, Takehara T.

Inflamm Bowel Dis. 2017 Dec;23(12):2172-2179. doi: 10.1097/MIB.0000000000001260.


Treatment outcomes of sialendoscopy for submandibular gland sialolithiasis: The minor axis of the sialolith is a regulative factor for the removal of sialoliths in the hilum of the submandibular gland using sialendoscopy alone.

Kondo N, Yoshihara T, Yamamura Y, Kusama K, Sakitani E, Seo Y, Tachikawa M, Kujirai K, Ono E, Maeda Y, Nojima T, Tamiya A, Sato E, Nonaka M.

Auris Nasus Larynx. 2018 Aug;45(4):772-776. doi: 10.1016/j.anl.2017.09.003. Epub 2017 Sep 19.


Periostin in inflammation and allergy.

Izuhara K, Nunomura S, Nanri Y, Ogawa M, Ono J, Mitamura Y, Yoshihara T.

Cell Mol Life Sci. 2017 Dec;74(23):4293-4303. doi: 10.1007/s00018-017-2648-0. Epub 2017 Sep 8. Review.


Natural attenuation of Fukushima-derived radiocesium in soils due to its vertical and lateral migration.

Konoplev A, Golosov V, Wakiyama Y, Takase T, Yoschenko V, Yoshihara T, Parenyuk O, Cresswell A, Ivanov M, Carradine M, Nanba K, Onda Y.

J Environ Radioact. 2018 Jun;186:23-33. doi: 10.1016/j.jenvrad.2017.06.019. Epub 2017 Aug 30.


Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression.

Fukunaka A, Fukada T, Bhin J, Suzuki L, Tsuzuki T, Takamine Y, Bin BH, Yoshihara T, Ichinoseki-Sekine N, Naito H, Miyatsuka T, Takamiya S, Sasaki T, Inagaki T, Kitamura T, Kajimura S, Watada H, Fujitani Y.

PLoS Genet. 2017 Aug 30;13(8):e1006950. doi: 10.1371/journal.pgen.1006950. eCollection 2017 Aug.

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