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Items: 14

1.

Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand.

Luther J, Yorgan TA, Rolvien T, Ulsamer L, Koehne T, Liao N, Keller D, Vollersen N, Teufel S, Neven M, Peters S, Schweizer M, Trumpp A, Rosigkeit S, Bockamp E, Mundlos S, Kornak U, Oheim R, Amling M, Schinke T, David JP.

Sci Transl Med. 2018 Nov 7;10(466). pii: eaau7137. doi: 10.1126/scitranslmed.aau7137.

PMID:
30404864
2.

The Lysosomal Protein Arylsulfatase B Is a Key Enzyme Involved in Skeletal Turnover.

Pohl S, Angermann A, Jeschke A, Hendrickx G, Yorgan TA, Makrypidi-Fraune G, Steigert A, Kuehn SC, Rolvien T, Schweizer M, Koehne T, Neven M, Winter O, Velho RV, Albers J, Streichert T, Pestka JM, Baldauf C, Breyer S, Stuecker R, Muschol N, Cox TM, Saftig P, Paganini C, Rossi A, Amling M, Braulke T, Schinke T.

J Bone Miner Res. 2018 Aug 3. doi: 10.1002/jbmr.3563. [Epub ahead of print]

PMID:
30075049
3.

Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells.

Di Lorenzo G, Velho RV, Winter D, Thelen M, Ahmadi S, Schweizer M, De Pace R, Cornils K, Yorgan TA, Grüb S, Hermans-Borgmeyer I, Schinke T, Müller-Loennies S, Braulke T, Pohl S.

Mol Cell Proteomics. 2018 Aug;17(8):1612-1626. doi: 10.1074/mcp.RA118.000720. Epub 2018 May 17.

PMID:
29773673
4.

Conditional mouse models support the role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in bone homeostasis.

Hendrickx G, Borra VM, Steenackers E, Yorgan TA, Hermans C, Boudin E, Waterval JJ, Jansen IDC, Aydemir TB, Kamerling N, Behets GJ, Plumeyer C, D'Haese PC, Busse B, Everts V, Lammens M, Mortier G, Cousins RJ, Schinke T, Stokroos RJ, Manni JJ, Van Hul W.

PLoS Genet. 2018 Apr 5;14(4):e1007321. doi: 10.1371/journal.pgen.1007321. eCollection 2018 Apr.

5.

Post-weaning epiphysiolysis causes distal femur dysplasia and foreshortened hindlimbs in fetuin-A-deficient mice.

Brylka LJ, Köppert S, Babler A, Kratz B, Denecke B, Yorgan TA, Etich J, Costa IG, Brachvogel B, Boor P, Schinke T, Jahnen-Dechent W.

PLoS One. 2017 Oct 31;12(10):e0187030. doi: 10.1371/journal.pone.0187030. eCollection 2017.

6.

High Bone Turnover in Mice Carrying a Pathogenic Notch2 Mutation Causing Hajdu-Cheney Syndrome.

Vollersen N, Hermans-Borgmeyer I, Cornils K, Fehse B, Rolvien T, Triviai I, Jeschke A, Oheim R, Amling M, Schinke T, Yorgan TA.

J Bone Miner Res. 2018 Jan;33(1):70-83. doi: 10.1002/jbmr.3283. Epub 2017 Sep 20.

PMID:
28856714
7.

The chaperone activity of 4PBA ameliorates the skeletal phenotype of Chihuahua, a zebrafish model for dominant osteogenesis imperfecta.

Gioia R, Tonelli F, Ceppi I, Biggiogera M, Leikin S, Fisher S, Tenedini E, Yorgan TA, Schinke T, Tian K, Schwartz JM, Forte F, Wagener R, Villani S, Rossi A, Forlino A.

Hum Mol Genet. 2017 Aug 1;26(15):2897-2911. doi: 10.1093/hmg/ddx171.

8.

Hypochlorhydria-induced calcium malabsorption does not affect fracture healing but increases post-traumatic bone loss in the intact skeleton.

Haffner-Luntzer M, Heilmann A, Heidler V, Liedert A, Schinke T, Amling M, Yorgan TA, Vom Scheidt A, Ignatius A.

J Orthop Res. 2016 Nov;34(11):1914-1921. doi: 10.1002/jor.23221. Epub 2016 Mar 14.

9.

Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I.

Kuehn SC, Koehne T, Cornils K, Markmann S, Riedel C, Pestka JM, Schweizer M, Baldauf C, Yorgan TA, Krause M, Keller J, Neven M, Breyer S, Stuecker R, Muschol N, Busse B, Braulke T, Fehse B, Amling M, Schinke T.

Hum Mol Genet. 2015 Dec 15;24(24):7075-86. doi: 10.1093/hmg/ddv407. Epub 2015 Oct 1.

PMID:
26427607
10.

Immediate effects of retinoic acid on gene expression in primary murine osteoblasts.

Yorgan TA, Heckt T, Rendenbach C, Helmis C, Seitz S, Streichert T, Amling M, Schinke T.

J Bone Miner Metab. 2016 Mar;34(2):161-70. doi: 10.1007/s00774-015-0666-2. Epub 2015 May 9.

PMID:
25956707
11.

The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5.

Yorgan TA, Peters S, Jeschke A, Benisch P, Jakob F, Amling M, Schinke T.

J Bone Miner Res. 2015 Jul;30(7):1175-83. doi: 10.1002/jbmr.2461. Epub 2015 Jun 8.

12.

Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity.

Bartelt A, Beil FT, Müller B, Koehne T, Yorgan TA, Heine M, Yilmaz T, Rüther W, Heeren J, Schinke T, Niemeier A.

Bone. 2014 May;62:90-8. doi: 10.1016/j.bone.2014.01.001. Epub 2014 Jan 16.

PMID:
24440515
13.

Relevance of Wnt signaling for osteoanabolic therapy.

Yorgan TA, Schinke T.

Mol Cell Ther. 2014 Jul 14;2:22. doi: 10.1186/2052-8426-2-22. eCollection 2014. Review.

14.

Effects of extracellular phosphate on gene expression in murine osteoblasts.

Rendenbach C, Yorgan TA, Heckt T, Otto B, Baldauf C, Jeschke A, Streichert T, David JP, Amling M, Schinke T.

Calcif Tissue Int. 2014 May;94(5):474-83. doi: 10.1007/s00223-013-9831-6. Epub 2013 Dec 24.

PMID:
24366459

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