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Inhibition of T cell activation and function by the adaptor protein CIN85.
Kong MS, Hashimoto-Tane A, Kawashima Y, Sakuma M, Yokosuka T, Kometani K, Onishi R, Carpino N, Ohara O, Kurosaki T, Phua KK, Saito T.
Sci Signal. 2019 Feb 5;12(567). pii: eaav4373. doi: 10.1126/scisignal.aav4373.
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Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.
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The immunological synapse, TCR microclusters, and T cell activation.
Yokosuka T, Saito T.
Curr Top Microbiol Immunol. 2010;340:81-107. doi: 10.1007/978-3-642-03858-7_5. Review.
CRTAM confers late-stage activation of CD8+ T cells to regulate retention within lymph node.
Takeuchi A, Itoh Y, Takumi A, Ishihara C, Arase N, Yokosuka T, Koseki H, Yamasaki S, Takai Y, Miyoshi J, Ogasawara K, Saito T.
J Immunol. 2009 Oct 1;183(7):4220-8. doi: 10.4049/jimmunol.0901248. Epub 2009 Sep 14.
Suppressed neutrophil function in children with acute lymphoblastic leukemia.
Tanaka F, Goto H, Yokosuka T, Yanagimachi M, Kajiwara R, Naruto T, Nishimaki S, Yokota S.
Int J Hematol. 2009 Oct;90(3):311-317. doi: 10.1007/s12185-009-0412-4. Epub 2009 Sep 2.
Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters.
Immunol Rev. 2009 May;229(1):27-40. doi: 10.1111/j.1600-065X.2009.00779.x. Review.
Chemo-sensitivity in a panel of B-cell precursor acute lymphoblastic leukemia cell lines, YCUB series, derived from children.
Goto H, Naruto T, Tanoshima R, Kato H, Yokosuka T, Yanagimachi M, Fujii H, Yokota S, Komine H.
Leuk Res. 2009 Oct;33(10):1386-91. doi: 10.1016/j.leukres.2008.12.003. Epub 2009 Jan 20.
Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation.
Yokosuka T, Kobayashi W, Sakata-Sogawa K, Takamatsu M, Hashimoto-Tane A, Dustin ML, Tokunaga M, Saito T.
Immunity. 2008 Oct 17;29(4):589-601. doi: 10.1016/j.immuni.2008.08.011. Epub 2008 Oct 9.
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