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Items: 1 to 50 of 163

1.

Profiling of bioactive lipids in different dendritic cell subsets using an improved multiplex quantitative LC-MS/MS method.

Ohba M, Saeki K, Koga T, Okuno T, Kobayashi Y, Yokomizo T.

Biochem Biophys Res Commun. 2018 Jun 12. pii: S0006-291X(18)31339-1. doi: 10.1016/j.bbrc.2018.06.026. [Epub ahead of print]

PMID:
29890138
2.

Leukotriene receptors as potential therapeutic targets.

Yokomizo T, Nakamura M, Shimizu T.

J Clin Invest. 2018 Jul 2;128(7):2691-2701. doi: 10.1172/JCI97946. Epub 2018 May 14.

3.

The Relationship between TP53 Gene Status and Carboxylesterase 2 Expression in Human Colorectal Cancer.

Ishimine M, Lee HC, Nakaoka H, Orita H, Kobayashi T, Mizuguchi K, Endo M, Inoue I, Sato K, Yokomizo T.

Dis Markers. 2018 Jan 31;2018:5280736. doi: 10.1155/2018/5280736. eCollection 2018.

4.

Applications of mass spectrometry-based targeted and non-targeted lipidomics.

Lee HC, Yokomizo T.

Biochem Biophys Res Commun. 2018 Mar 13. pii: S0006-291X(18)30567-9. doi: 10.1016/j.bbrc.2018.03.081. [Epub ahead of print]

PMID:
29534960
5.

Deuteration and selective labeling of alanine methyl groups of β2-adrenergic receptor expressed in a baculovirus-insect cell expression system.

Kofuku Y, Yokomizo T, Imai S, Shiraishi Y, Natsume M, Itoh H, Inoue M, Nakata K, Igarashi S, Yamaguchi H, Mizukoshi T, Suzuki EI, Ueda T, Shimada I.

J Biomol NMR. 2018 Jul;71(3):185-192. doi: 10.1007/s10858-018-0174-5. Epub 2018 Mar 8.

PMID:
29520682
6.

Endurance exercise training and high-fat diet differentially affect composition of diacylglycerol molecular species in rat skeletal muscle.

Kawanishi N, Takagi K, Lee HC, Nakano D, Okuno T, Yokomizo T, Machida S.

Am J Physiol Regul Integr Comp Physiol. 2018 Jun 1;314(6):R892-R901. doi: 10.1152/ajpregu.00371.2017. Epub 2018 Feb 14.

7.

Altered eicosanoid production and phospholipid remodeling during cell culture.

Okuno T, Gijón MA, Zarini S, Martin SA, Barkley RM, Johnson CA, Ohba M, Yokomizo T, Murphy RC.

J Lipid Res. 2018 Mar;59(3):542-549. doi: 10.1194/jlr.M083030. Epub 2018 Jan 20.

PMID:
29353239
8.

Leukotriene B4 receptor 2 regulates the proliferation, migration, and barrier integrity of bronchial epithelial cells.

Liu M, Shen J, Yuan H, Chen F, Song H, Qin H, Li Y, Xu J, Ye Q, Li S, Saeki K, Yokomizo T.

J Cell Physiol. 2018 Aug;233(8):6117-6124. doi: 10.1002/jcp.26455. Epub 2018 Mar 7.

PMID:
29323699
9.

Na+-mimicking ligands stabilize the inactive state of leukotriene B4 receptor BLT1.

Hori T, Okuno T, Hirata K, Yamashita K, Kawano Y, Yamamoto M, Hato M, Nakamura M, Shimizu T, Yokomizo T, Miyano M, Yokoyama S.

Nat Chem Biol. 2018 Mar;14(3):262-269. doi: 10.1038/nchembio.2547. Epub 2018 Jan 8.

PMID:
29309055
10.

Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function.

Nieke S, Yasmin N, Kakugawa K, Yokomizo T, Muroi S, Taniuchi I.

BMC Dev Biol. 2017 Oct 18;17(1):14. doi: 10.1186/s12861-017-0156-y.

11.

Identification, signaling, and functions of LTB4 receptors.

Saeki K, Yokomizo T.

Semin Immunol. 2017 Oct;33:30-36. doi: 10.1016/j.smim.2017.07.010. Review.

12.

Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B4 receptor 2.

Iwamoto S, Koga T, Ohba M, Okuno T, Koike M, Murakami A, Matsuda A, Yokomizo T.

Sci Rep. 2017 Oct 16;7(1):13267. doi: 10.1038/s41598-017-13122-8.

13.

Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1.

Sasaki F, Koga T, Saeki K, Okuno T, Kazuno S, Fujimura T, Ohkawa Y, Yokomizo T.

PLoS One. 2017 Sep 18;12(9):e0185133. doi: 10.1371/journal.pone.0185133. eCollection 2017.

14.

Urinary prostaglandin D2 metabolite excretion during the first six months of life was significantly lower in breast-fed than formula-fed infants.

Shoji H, Ikeda N, Kitamura T, Suganuma H, Ohba M, Okuno T, Yokomizo T, Shimizu T.

Acta Paediatr. 2018 Jan;107(1):95-100. doi: 10.1111/apa.14068. Epub 2017 Sep 27.

PMID:
28898456
15.

Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration.

Takeda T, Komiya Y, Koga T, Ishida T, Ishii Y, Kikuta Y, Nakaya M, Kurose H, Yokomizo T, Shimizu T, Uchi H, Furue M, Yamada H.

J Biol Chem. 2017 Jun 23;292(25):10586-10599. doi: 10.1074/jbc.M116.764332. Epub 2017 May 9.

16.

Generation and characterization of a human-mouse chimeric high-affinity antibody that detects the DYKDDDDK FLAG peptide.

Ikeda K, Koga T, Sasaki F, Ueno A, Saeki K, Okuno T, Yokomizo T.

Biochem Biophys Res Commun. 2017 May 13;486(4):1077-1082. doi: 10.1016/j.bbrc.2017.03.165. Epub 2017 Apr 1.

PMID:
28377223
17.

Runx Family Genes in Tissue Stem Cell Dynamics.

Wang CQ, Mok MM, Yokomizo T, Tergaonkar V, Osato M.

Adv Exp Med Biol. 2017;962:117-138. doi: 10.1007/978-981-10-3233-2_9. Review.

PMID:
28299655
18.

Intravenous anesthetic propofol binds to 5-lipoxygenase and attenuates leukotriene B4 production.

Okuno T, Koutsogiannaki S, Ohba M, Chamberlain M, Bu W, Lin FY, Eckenhoff RG, Yokomizo T, Yuki K.

FASEB J. 2017 Apr;31(4):1584-1594. doi: 10.1096/fj.201601095R. Epub 2017 Jan 9.

19.

Inhibition of Leukotriene B4 Action Mitigates Intracerebral Hemorrhage-Associated Pathological Events in Mice.

Hijioka M, Anan J, Ishibashi H, Kurauchi Y, Hisatsune A, Seki T, Koga T, Yokomizo T, Shimizu T, Katsuki H.

J Pharmacol Exp Ther. 2017 Mar;360(3):399-408. doi: 10.1124/jpet.116.238824. Epub 2016 Dec 29.

20.

From the Cover: Prolonged Exposure to Volatile Anesthetic Isoflurane Worsens the Outcome of Polymicrobial Abdominal Sepsis.

Koutsogiannaki S, Schaefers MM, Okuno T, Ohba M, Yokomizo T, Priebe GP, DiNardo JA, Sulpicio SG, Yuki K.

Toxicol Sci. 2017 Apr 1;156(2):402-411. doi: 10.1093/toxsci/kfw261.

21.

Receptor for Advanced Glycation End Products Regulates Leukotriene B4 Receptor 1 Signaling.

Ichiki T, Koga T, Yokomizo T.

DNA Cell Biol. 2016 Dec;35(12):747-750. Epub 2016 Nov 10.

PMID:
27830944
22.

A synthetic leukotriene B4 receptor type 2 agonist accelerates the cutaneous wound healing process in diabetic rats by indirect stimulation of fibroblasts and direct stimulation of keratinocytes.

Luo L, Tanaka R, Kanazawa S, Lu F, Hayashi A, Yokomizo T, Mizuno H.

J Diabetes Complications. 2017 Jan;31(1):13-20. doi: 10.1016/j.jdiacomp.2016.09.002. Epub 2016 Sep 14.

23.

Leukotriene B4 receptor type 2 protects against pneumolysin-dependent acute lung injury.

Shigematsu M, Koga T, Ishimori A, Saeki K, Ishii Y, Taketomi Y, Ohba M, Jo-Watanabe A, Okuno T, Harada N, Harayama T, Shindou H, Li JD, Murakami M, Hoka S, Yokomizo T.

Sci Rep. 2016 Oct 5;6:34560. doi: 10.1038/srep34560.

24.

BLT1 signalling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophils.

Kojo K, Ito Y, Eshima K, Nishizawa N, Ohkubo H, Yokomizo T, Shimizu T, Watanabe M, Majima M.

Sci Rep. 2016 Jul 11;6:29650. doi: 10.1038/srep29650.

25.

Lack of Phenotypical and Morphological Evidences of Endothelial to Hematopoietic Transition in the Murine Embryonic Head during Hematopoietic Stem Cell Emergence.

Iizuka K, Yokomizo T, Watanabe N, Tanaka Y, Osato M, Takaku T, Komatsu N.

PLoS One. 2016 May 26;11(5):e0156427. doi: 10.1371/journal.pone.0156427. eCollection 2016.

26.

The leukotriene B4 receptor BLT2 protects barrier function via actin polymerization with phosphorylation of myosin phosphatase target subunit 1 in human keratinocytes.

Chiba T, Nakahara T, Hashimoto-Hachiya A, Yokomizo T, Uchi H, Furue M.

Exp Dermatol. 2016 Jul;25(7):532-6. doi: 10.1111/exd.12976. Epub 2016 Apr 15.

PMID:
26896822
27.

CD10-Equipped Melanoma Cells Acquire Highly Potent Tumorigenic Activity: A Plausible Explanation of Their Significance for a Poor Prognosis.

Oba J, Nakahara T, Hashimoto-Hachiya A, Liu M, Abe T, Hagihara A, Yokomizo T, Furue M.

PLoS One. 2016 Feb 16;11(2):e0149285. doi: 10.1371/journal.pone.0149285. eCollection 2016.

28.

Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors.

Kaimakis P, de Pater E, Eich C, Solaimani Kartalaei P, Kauts ML, Vink CS, van der Linden R, Jaegle M, Yokomizo T, Meijer D, Dzierzak E.

Blood. 2016 Mar 17;127(11):1426-37. doi: 10.1182/blood-2015-10-673749. Epub 2016 Feb 1.

29.

Modulation of leukotriene B4 receptor 1 signaling by receptor for advanced glycation end products (RAGE).

Ichiki T, Koga T, Okuno T, Saeki K, Yamamoto Y, Yamamoto H, Sakaguchi M, Yokomizo T.

FASEB J. 2016 May;30(5):1811-22. doi: 10.1096/fj.201500117. Epub 2016 Jan 26.

PMID:
26813973
30.

Integrative genomic and proteomic analyses identifies glycerol-3-phosphate acyltransferase as a target of low-dose ionizing radiation in EBV infected-B cells.

Tabe Y, Hatanaka Y, Nakashiro M, Sekihara K, Yamamoto S, Matsushita H, Kazuno S, Fujimura T, Ikegami T, Nakanaga K, Matsumoto H, Ueno T, Aoki J, Yokomizo T, Konopleva M, Andreeff M, Miida T, Iwabuchi K, Sasai K.

Int J Radiat Biol. 2016;92(1):24-34. doi: 10.3109/09553002.2015.1106021. Epub 2015 Nov 19.

PMID:
26809544
31.

RUNX1 haploinsufficiency results in granulocyte colony-stimulating factor hypersensitivity.

Chin DW, Sakurai M, Nah GS, Du L, Jacob B, Yokomizo T, Matsumura T, Suda T, Huang G, Fu XY, Ito Y, Nakajima H, Osato M.

Blood Cancer J. 2016 Jan 8;6:e379. doi: 10.1038/bcj.2015.105.

32.

Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins.

Ishii Y, Saeki K, Liu M, Sasaki F, Koga T, Kitajima K, Meno C, Okuno T, Yokomizo T.

FASEB J. 2016 Feb;30(2):933-47. doi: 10.1096/fj.15-279653. Epub 2015 Nov 2.

PMID:
26527063
33.

An inhaled phosphodiesterase 4 inhibitor E6005 suppresses pulmonary inflammation in mice.

Kubota S, Watanabe M, Shirato M, Okuno T, Higashimoto I, Machida K, Yokomizo T, Inoue H.

Eur J Pharmacol. 2015 Dec 5;768:41-8. doi: 10.1016/j.ejphar.2015.10.013. Epub 2015 Oct 8.

PMID:
26455478
34.

Resolvin E1 inhibits dendritic cell migration in the skin and attenuates contact hypersensitivity responses.

Sawada Y, Honda T, Hanakawa S, Nakamizo S, Murata T, Ueharaguchi-Tanada Y, Ono S, Amano W, Nakajima S, Egawa G, Tanizaki H, Otsuka A, Kitoh A, Dainichi T, Ogawa N, Kobayashi Y, Yokomizo T, Arita M, Nakamura M, Miyachi Y, Kabashima K.

J Exp Med. 2015 Oct 19;212(11):1921-30. doi: 10.1084/jem.20150381. Epub 2015 Oct 5.

35.

The leukotriene B4 receptor BLT1 is stabilized by transmembrane helix capping mutations.

Hori T, Nakamura M, Yokomizo T, Shimizu T, Miyano M.

Biochem Biophys Rep. 2015 Sep 26;4:243-249. doi: 10.1016/j.bbrep.2015.09.007. eCollection 2015 Dec.

36.

The absence of the leukotriene B4 receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury.

Asahara M, Ito N, Yokomizo T, Nakamura M, Shimizu T, Yamada Y.

Mol Pain. 2015 Mar 12;11:11. doi: 10.1186/s12990-015-0010-9.

37.

The absence of the leukotriene B4 receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury.

Asahara M, Ito N, Yokomizo T, Nakamura M, Shimizu T, Yamada Y.

Mol Pain. 2015 Dec;11(1):10. doi: 10.1186/s12990-015-0010-9. Epub 2015 Mar 12.

PMID:
25775965
38.

Biochemical characterization of three BLT receptors in zebrafish.

Okuno T, Ishitani T, Yokomizo T.

PLoS One. 2015 Mar 4;10(3):e0117888. doi: 10.1371/journal.pone.0117888. eCollection 2015.

39.

ROCK-isoform-specific polarization of macrophages associated with age-related macular degeneration.

Zandi S, Nakao S, Chun KH, Fiorina P, Sun D, Arita R, Zhao M, Kim E, Schueller O, Campbell S, Taher M, Melhorn MI, Schering A, Gatti F, Tezza S, Xie F, Vergani A, Yoshida S, Ishikawa K, Yamaguchi M, Sasaki F, Schmidt-Ullrich R, Hata Y, Enaida H, Yuzawa M, Yokomizo T, Kim YB, Sweetnam P, Ishibashi T, Hafezi-Moghadam A.

Cell Rep. 2015 Feb 24;10(7):1173-86. doi: 10.1016/j.celrep.2015.01.050. Epub 2015 Feb 19.

40.

Hematopoietic stem cell enhancer: a powerful tool in stem cell biology.

Koh CP, Ng CE, Nah GS, Wang CQ, Tergaonkar V, Matsumura T, Yokomizo T, Suda T, Osato M.

Histol Histopathol. 2015 Jun;30(6):661-72. doi: 10.14670/HH-30.661. Epub 2015 Jan 9. Review.

PMID:
25574754
41.

The role of leukotrienes in allergic diseases.

Liu M, Yokomizo T.

Allergol Int. 2015 Jan;64(1):17-26. doi: 10.1016/j.alit.2014.09.001. Epub 2014 Nov 22. Review.

42.

Whole-transcriptome analysis of endothelial to hematopoietic stem cell transition reveals a requirement for Gpr56 in HSC generation.

Solaimani Kartalaei P, Yamada-Inagawa T, Vink CS, de Pater E, van der Linden R, Marks-Bluth J, van der Sloot A, van den Hout M, Yokomizo T, van Schaick-Solernó ML, Delwel R, Pimanda JE, van IJcken WF, Dzierzak E.

J Exp Med. 2015 Jan 12;212(1):93-106. doi: 10.1084/jem.20140767. Epub 2014 Dec 29.

43.

Two distinct leukotriene B4 receptors, BLT1 and BLT2.

Yokomizo T.

J Biochem. 2015 Feb;157(2):65-71. doi: 10.1093/jb/mvu078. Epub 2014 Dec 4.

PMID:
25480980
44.

Individual variation of human S1P₁ coding sequence leads to heterogeneity in receptor function and drug interactions.

Obinata H, Gutkind S, Stitham J, Okuno T, Yokomizo T, Hwa J, Hla T.

J Lipid Res. 2014 Dec;55(12):2665-75. doi: 10.1194/jlr.P054163. Epub 2014 Oct 7.

45.

[Combined spinal-epidural anesthesia for a patient with HTLV-1 associated myelopathy].

Yokomizo T, Hiraki T, Mishima Y, Ushijima K.

Masui. 2014 Aug;63(8):918-20. Japanese.

PMID:
25199333
46.

Development of a bifunctional filter for prion protein and leukoreduction of red blood cell components.

Yokomizo T, Kai T, Miura M, Ohto H.

Transfusion. 2015 Feb;55(2):330-6. doi: 10.1111/trf.12839. Epub 2014 Sep 1.

PMID:
25178436
47.

IL-27 affects helper T cell responses via regulation of PGE2 production by macrophages.

Sato Y, Hara H, Okuno T, Ozaki N, Suzuki S, Yokomizo T, Kaisho T, Yoshida H.

Biochem Biophys Res Commun. 2014 Aug 22;451(2):215-21. doi: 10.1016/j.bbrc.2014.07.096. Epub 2014 Aug 1.

PMID:
25088998
48.

Circulation-independent differentiation pathway from extraembryonic mesoderm toward hematopoietic stem cells via hemogenic angioblasts.

Tanaka Y, Sanchez V, Takata N, Yokomizo T, Yamanaka Y, Kataoka H, Hoppe PS, Schroeder T, Nishikawa S.

Cell Rep. 2014 Jul 10;8(1):31-9. doi: 10.1016/j.celrep.2014.05.055. Epub 2014 Jun 26.

49.

Epithelial-mesenchymal status renders differential responses to cisplatin in ovarian cancer.

Miow QH, Tan TZ, Ye J, Lau JA, Yokomizo T, Thiery JP, Mori S.

Oncogene. 2015 Apr 9;34(15):1899-907. doi: 10.1038/onc.2014.136. Epub 2014 May 26.

PMID:
24858042
50.

12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor.

Liu M, Saeki K, Matsunobu T, Okuno T, Koga T, Sugimoto Y, Yokoyama C, Nakamizo S, Kabashima K, Narumiya S, Shimizu T, Yokomizo T.

J Exp Med. 2014 Jun 2;211(6):1063-78. doi: 10.1084/jem.20132063. Epub 2014 May 12.

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