Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 186

1.

Structural equilibrium underlying ligand-dependent activation of β2-adrenoreceptor.

Imai S, Yokomizo T, Kofuku Y, Shiraishi Y, Ueda T, Shimada I.

Nat Chem Biol. 2020 Jan 20. doi: 10.1038/s41589-019-0457-5. [Epub ahead of print]

PMID:
31959965
2.

Leukotriene B4 receptor type 2 (BLT2) accelerates the healing of intestinal lesions by promoting epithelial cell proliferation.

Matsumoto Y, Matsuya Y, Nagai K, Amagase K, Saeki K, Matsumoto K, Yokomizo T, Shinichi K.

J Pharmacol Exp Ther. 2020 Jan 15. pii: jpet.119.263145. doi: 10.1124/jpet.119.263145. [Epub ahead of print]

3.

Loss of autophagy impairs physiological steatosis by accumulation of NCoR1.

Takahashi SS, Sou YS, Saito T, Kuma A, Yabe T, Sugiura Y, Lee HC, Suematsu M, Yokomizo T, Koike M, Terai S, Mizushima N, Waguri S, Komatsu M.

Life Sci Alliance. 2019 Dec 26;3(1). pii: e201900513. doi: 10.26508/lsa.201900513. Print 2020 Jan.

4.

Liver-specific deletion of Ngly1 causes abnormal nuclear morphology and lipid metabolism under food stress.

Fujihira H, Masahara-Negishi Y, Akimoto Y, Hirayama H, Lee HC, Story BA, Mueller WF, Jakob P, Clauder-Münster S, Steinmetz LM, Radhakrishnan SK, Kawakami H, Kamada Y, Miyoshi E, Yokomizo T, Suzuki T.

Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1;1866(3):165588. doi: 10.1016/j.bbadis.2019.165588. Epub 2019 Nov 13.

PMID:
31733337
5.

Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system.

Okuno T, Koutsogiannaki S, Hou L, Bu W, Ohto U, Eckenhoff RG, Yokomizo T, Yuki K.

FASEB J. 2019 Dec;33(12):14528-14541. doi: 10.1096/fj.201901570R. Epub 2019 Nov 2.

PMID:
31675483
6.

The volatile anesthetic sevoflurane reduces neutrophil apoptosis via Fas death domain-Fas-associated death domain interaction.

Koutsogiannaki S, Hou L, Babazada H, Okuno T, Blazon-Brown N, Soriano SG, Yokomizo T, Yuki K.

FASEB J. 2019 Nov;33(11):12668-12679. doi: 10.1096/fj.201901360R. Epub 2019 Aug 30.

PMID:
31513427
7.

The roles of omega-3 fatty acids and resolvins in allergic conjunctivitis.

Hirakata T, Yokomizo T, Matsuda A.

Curr Opin Allergy Clin Immunol. 2019 Oct;19(5):517-525. doi: 10.1097/ACI.0000000000000561.

PMID:
31465315
8.

Dietary supplementation of omega-3 fatty acid eicosapentaenoic acid does not ameliorate pruritus in murine models of atopic dermatitis and psoriasis.

Lee HC, Tominaga M, Yasukawa K, Ohba M, Takahashi N, Honda K, Okuno T, Takamori K, Yokomizo T.

J Dermatol Sci. 2019 Sep;95(3):130-133. doi: 10.1016/j.jdermsci.2019.07.010. Epub 2019 Jul 27. No abstract available.

PMID:
31383390
9.

The Role of Leukotrienes as Potential Therapeutic Targets in Allergic Disorders.

Jo-Watanabe A, Okuno T, Yokomizo T.

Int J Mol Sci. 2019 Jul 22;20(14). pii: E3580. doi: 10.3390/ijms20143580. Review.

10.

An Alternative Pathway to Leukotriene B4 Enantiomers Involving a 1,8-Diol-Forming Reaction of an Algal Oxylipin.

Jagusch H, Werner M, Okuno T, Yokomizo T, Werz O, Pohnert G.

Org Lett. 2019 Jun 21;21(12):4667-4670. doi: 10.1021/acs.orglett.9b01554. Epub 2019 Jun 13.

PMID:
31192616
11.

BLT1 mediates commensal bacteria-dependent innate immune signals to enhance antigen-specific intestinal IgA responses.

Nagatake T, Hirata SI, Koga T, Kuroda E, Kobari S, Suzuki H, Hosomi K, Matsumoto N, Yanrismet Y, Shimojou M, Morimoto S, Sasaki F, Ishii KJ, Yokomizo T, Kunisawa J.

Mucosal Immunol. 2019 Sep;12(5):1082-1091. doi: 10.1038/s41385-019-0175-z. Epub 2019 May 29.

PMID:
31142830
12.

The leukotriene receptors as therapeutic targets of inflammatory diseases.

Sasaki F, Yokomizo T.

Int Immunol. 2019 Aug 23;31(9):607-615. doi: 10.1093/intimm/dxz044.

PMID:
31135881
13.

Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors.

Yokomizo T, Watanabe N, Umemoto T, Matsuo J, Harai R, Kihara Y, Nakamura E, Tada N, Sato T, Takaku T, Shimono A, Takizawa H, Nakagata N, Mori S, Kurokawa M, Tenen DG, Osato M, Suda T, Komatsu N.

J Exp Med. 2019 Jul 1;216(7):1599-1614. doi: 10.1084/jem.20181399. Epub 2019 May 10.

14.

Cyclooxygenase inhibition in mice heightens adaptive- and innate-type responses against inhaled protease allergen and IL-33.

Maruyama N, Takai T, Kamijo S, Suchiva P, Ohba M, Takeshige T, Suzuki M, Hara M, Matsuno K, Harada S, Harada N, Nakae S, Sudo K, Okuno T, Yokomizo T, Ogawa H, Okumura K, Ikeda S.

Allergy. 2019 Nov;74(11):2237-2240. doi: 10.1111/all.13831. Epub 2019 Jul 15. No abstract available.

PMID:
31006115
15.

Correction: Role of the high-affinity leukotriene B4 receptor signaling in fibrosis after unilateral ureteral obstruction in mice.

Kamata M, Amano H, Ito Y, Fujita T, Otaka F, Hosono K, Kamata K, Takeuchi Y, Yokomizo T, Shimizu T, Majima M.

PLoS One. 2019 Apr 15;14(4):e0215625. doi: 10.1371/journal.pone.0215625. eCollection 2019.

16.

Autophagy regulates lipid metabolism through selective turnover of NCoR1.

Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, Okuda S, Lee HC, Ikeda K, Kanegae Y, Saito I, Auwerx J, Motohashi H, Suematsu M, Soga T, Yokomizo T, Waguri S, Mizushima N, Komatsu M.

Nat Commun. 2019 Apr 5;10(1):1567. doi: 10.1038/s41467-019-08829-3.

17.

Papaverine identified as an inhibitor of high mobility group box 1/receptor for advanced glycation end-products interaction suppresses high mobility group box 1-mediated inflammatory responses.

Tamada K, Nakajima S, Ogawa N, Inada M, Shibasaki H, Sato A, Takasawa R, Yoshimori A, Suzuki Y, Watanabe N, Oyama T, Abe H, Inoue S, Abe T, Yokomizo T, Tanuma S.

Biochem Biophys Res Commun. 2019 Apr 9;511(3):665-670. doi: 10.1016/j.bbrc.2019.01.136. Epub 2019 Feb 27.

PMID:
30826057
18.

Role of the high-affinity leukotriene B4 receptor signaling in fibrosis after unilateral ureteral obstruction in mice.

Kamata M, Amano H, Ito Y, Fujita T, Otaka F, Hosono K, Kamata K, Takeuchi Y, Yokomizo T, Shimizu T, Majima M.

PLoS One. 2019 Feb 28;14(2):e0202842. doi: 10.1371/journal.pone.0202842. eCollection 2019. Erratum in: PLoS One. 2019 Apr 15;14(4):e0215625.

19.

Transcriptome profiling of refractory atopic keratoconjunctivitis by RNA sequencing.

Matsuda A, Asada Y, Suita N, Iwamoto S, Hirakata T, Yokoi N, Ohkawa Y, Okada Y, Yokomizo T, Ebihara N.

J Allergy Clin Immunol. 2019 Apr;143(4):1610-1614.e6. doi: 10.1016/j.jaci.2018.11.007. Epub 2018 Nov 22. No abstract available.

PMID:
30471305
20.

Biological functions of 12(S)-hydroxyheptadecatrienoic acid as a ligand of leukotriene B4 receptor 2.

Okuno T, Yokomizo T.

Inflamm Regen. 2018 Oct 29;38:29. doi: 10.1186/s41232-018-0087-4. eCollection 2018. Review.

21.

Dietary ω-3 fatty acids alter the lipid mediator profile and alleviate allergic conjunctivitis without modulating Th2 immune responses.

Hirakata T, Lee HC, Ohba M, Saeki K, Okuno T, Murakami A, Matsuda A, Yokomizo T.

FASEB J. 2019 Mar;33(3):3392-3403. doi: 10.1096/fj.201801805R. Epub 2018 Nov 1.

22.

Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models.

Sasaki F, Koga T, Ohba M, Saeki K, Okuno T, Ishikawa K, Nakama T, Nakao S, Yoshida S, Ishibashi T, Ahmadieh H, Kanavi MR, Hafezi-Moghadam A, Penninger JM, Sonoda KH, Yokomizo T.

JCI Insight. 2018 Sep 20;3(18). pii: 96902. doi: 10.1172/jci.insight.96902. eCollection 2018 Sep 20.

23.

Stepwise phosphorylation of leukotriene B4 receptor 1 defines cellular responses to leukotriene B4.

Nakanishi Y, Tan M, Ichiki T, Inoue A, Yoshihara JI, Maekawa N, Takenoshita I, Yanagida K, Yamahira S, Yamaguchi S, Aoki J, Nagamune T, Yokomizo T, Shimizu T, Nakamura M.

Sci Signal. 2018 Aug 21;11(544). pii: eaao5390. doi: 10.1126/scisignal.aao5390.

PMID:
30131369
24.

Profiling of bioactive lipids in different dendritic cell subsets using an improved multiplex quantitative LC-MS/MS method.

Ohba M, Saeki K, Koga T, Okuno T, Kobayashi Y, Yokomizo T.

Biochem Biophys Res Commun. 2018 Oct 7;504(3):562-568. doi: 10.1016/j.bbrc.2018.06.026. Epub 2018 Jun 12.

PMID:
29890138
25.

Leukotriene receptors as potential therapeutic targets.

Yokomizo T, Nakamura M, Shimizu T.

J Clin Invest. 2018 Jul 2;128(7):2691-2701. doi: 10.1172/JCI97946. Epub 2018 May 14. Review.

26.

The Relationship between TP53 Gene Status and Carboxylesterase 2 Expression in Human Colorectal Cancer.

Ishimine M, Lee HC, Nakaoka H, Orita H, Kobayashi T, Mizuguchi K, Endo M, Inoue I, Sato K, Yokomizo T.

Dis Markers. 2018 Jan 31;2018:5280736. doi: 10.1155/2018/5280736. eCollection 2018.

27.

Applications of mass spectrometry-based targeted and non-targeted lipidomics.

Lee HC, Yokomizo T.

Biochem Biophys Res Commun. 2018 Oct 7;504(3):576-581. doi: 10.1016/j.bbrc.2018.03.081. Epub 2018 Mar 13. Review.

PMID:
29534960
28.

Deuteration and selective labeling of alanine methyl groups of β2-adrenergic receptor expressed in a baculovirus-insect cell expression system.

Kofuku Y, Yokomizo T, Imai S, Shiraishi Y, Natsume M, Itoh H, Inoue M, Nakata K, Igarashi S, Yamaguchi H, Mizukoshi T, Suzuki EI, Ueda T, Shimada I.

J Biomol NMR. 2018 Jul;71(3):185-192. doi: 10.1007/s10858-018-0174-5. Epub 2018 Mar 8.

PMID:
29520682
29.

Endurance exercise training and high-fat diet differentially affect composition of diacylglycerol molecular species in rat skeletal muscle.

Kawanishi N, Takagi K, Lee HC, Nakano D, Okuno T, Yokomizo T, Machida S.

Am J Physiol Regul Integr Comp Physiol. 2018 Jun 1;314(6):R892-R901. doi: 10.1152/ajpregu.00371.2017. Epub 2018 Feb 14.

30.

Altered eicosanoid production and phospholipid remodeling during cell culture.

Okuno T, Gijón MA, Zarini S, Martin SA, Barkley RM, Johnson CA, Ohba M, Yokomizo T, Murphy RC.

J Lipid Res. 2018 Mar;59(3):542-549. doi: 10.1194/jlr.M083030. Epub 2018 Jan 20.

31.

Leukotriene B4 receptor 2 regulates the proliferation, migration, and barrier integrity of bronchial epithelial cells.

Liu M, Shen J, Yuan H, Chen F, Song H, Qin H, Li Y, Xu J, Ye Q, Li S, Saeki K, Yokomizo T.

J Cell Physiol. 2018 Aug;233(8):6117-6124. doi: 10.1002/jcp.26455. Epub 2018 Mar 7.

PMID:
29323699
32.

Na+-mimicking ligands stabilize the inactive state of leukotriene B4 receptor BLT1.

Hori T, Okuno T, Hirata K, Yamashita K, Kawano Y, Yamamoto M, Hato M, Nakamura M, Shimizu T, Yokomizo T, Miyano M, Yokoyama S.

Nat Chem Biol. 2018 Mar;14(3):262-269. doi: 10.1038/nchembio.2547. Epub 2018 Jan 8.

PMID:
29309055
33.

Rapid Fabrication of a Crystalline Myristic Acid-Based Superhydrophobic Film with Corrosion Resistance on Magnesium Alloys by the Facile One-Step Immersion Process.

Ishizaki T, Shimada Y, Tsunakawa M, Lee H, Yokomizo T, Hisada S, Nakamura K.

ACS Omega. 2017 Nov 15;2(11):7904-7915. doi: 10.1021/acsomega.7b01256. eCollection 2017 Nov 30.

34.

Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function.

Nieke S, Yasmin N, Kakugawa K, Yokomizo T, Muroi S, Taniuchi I.

BMC Dev Biol. 2017 Oct 18;17(1):14. doi: 10.1186/s12861-017-0156-y.

35.

Identification, signaling, and functions of LTB4 receptors.

Saeki K, Yokomizo T.

Semin Immunol. 2017 Oct;33:30-36. doi: 10.1016/j.smim.2017.07.010. Review.

36.

Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B4 receptor 2.

Iwamoto S, Koga T, Ohba M, Okuno T, Koike M, Murakami A, Matsuda A, Yokomizo T.

Sci Rep. 2017 Oct 16;7(1):13267. doi: 10.1038/s41598-017-13122-8.

37.

Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1.

Sasaki F, Koga T, Saeki K, Okuno T, Kazuno S, Fujimura T, Ohkawa Y, Yokomizo T.

PLoS One. 2017 Sep 18;12(9):e0185133. doi: 10.1371/journal.pone.0185133. eCollection 2017.

38.

Urinary prostaglandin D2 metabolite excretion during the first six months of life was significantly lower in breast-fed than formula-fed infants.

Shoji H, Ikeda N, Kitamura T, Suganuma H, Ohba M, Okuno T, Yokomizo T, Shimizu T.

Acta Paediatr. 2018 Jan;107(1):95-100. doi: 10.1111/apa.14068. Epub 2017 Sep 27.

PMID:
28898456
39.

Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration.

Takeda T, Komiya Y, Koga T, Ishida T, Ishii Y, Kikuta Y, Nakaya M, Kurose H, Yokomizo T, Shimizu T, Uchi H, Furue M, Yamada H.

J Biol Chem. 2017 Jun 23;292(25):10586-10599. doi: 10.1074/jbc.M116.764332. Epub 2017 May 9.

40.

Generation and characterization of a human-mouse chimeric high-affinity antibody that detects the DYKDDDDK FLAG peptide.

Ikeda K, Koga T, Sasaki F, Ueno A, Saeki K, Okuno T, Yokomizo T.

Biochem Biophys Res Commun. 2017 May 13;486(4):1077-1082. doi: 10.1016/j.bbrc.2017.03.165. Epub 2017 Apr 1.

PMID:
28377223
41.

Runx Family Genes in Tissue Stem Cell Dynamics.

Wang CQ, Mok MM, Yokomizo T, Tergaonkar V, Osato M.

Adv Exp Med Biol. 2017;962:117-138. doi: 10.1007/978-981-10-3233-2_9. Review.

PMID:
28299655
42.

Intravenous anesthetic propofol binds to 5-lipoxygenase and attenuates leukotriene B4 production.

Okuno T, Koutsogiannaki S, Ohba M, Chamberlain M, Bu W, Lin FY, Eckenhoff RG, Yokomizo T, Yuki K.

FASEB J. 2017 Apr;31(4):1584-1594. doi: 10.1096/fj.201601095R. Epub 2017 Jan 9.

43.

Inhibition of Leukotriene B4 Action Mitigates Intracerebral Hemorrhage-Associated Pathological Events in Mice.

Hijioka M, Anan J, Ishibashi H, Kurauchi Y, Hisatsune A, Seki T, Koga T, Yokomizo T, Shimizu T, Katsuki H.

J Pharmacol Exp Ther. 2017 Mar;360(3):399-408. doi: 10.1124/jpet.116.238824. Epub 2016 Dec 29.

PMID:
28035009
44.

From the Cover: Prolonged Exposure to Volatile Anesthetic Isoflurane Worsens the Outcome of Polymicrobial Abdominal Sepsis.

Koutsogiannaki S, Schaefers MM, Okuno T, Ohba M, Yokomizo T, Priebe GP, DiNardo JA, Sulpicio SG, Yuki K.

Toxicol Sci. 2017 Apr 1;156(2):402-411. doi: 10.1093/toxsci/kfw261.

45.

Receptor for Advanced Glycation End Products Regulates Leukotriene B4 Receptor 1 Signaling.

Ichiki T, Koga T, Yokomizo T.

DNA Cell Biol. 2016 Dec;35(12):747-750. Epub 2016 Nov 10.

PMID:
27830944
46.

A synthetic leukotriene B4 receptor type 2 agonist accelerates the cutaneous wound healing process in diabetic rats by indirect stimulation of fibroblasts and direct stimulation of keratinocytes.

Luo L, Tanaka R, Kanazawa S, Lu F, Hayashi A, Yokomizo T, Mizuno H.

J Diabetes Complications. 2017 Jan;31(1):13-20. doi: 10.1016/j.jdiacomp.2016.09.002. Epub 2016 Sep 14.

47.

Leukotriene B4 receptor type 2 protects against pneumolysin-dependent acute lung injury.

Shigematsu M, Koga T, Ishimori A, Saeki K, Ishii Y, Taketomi Y, Ohba M, Jo-Watanabe A, Okuno T, Harada N, Harayama T, Shindou H, Li JD, Murakami M, Hoka S, Yokomizo T.

Sci Rep. 2016 Oct 5;6:34560. doi: 10.1038/srep34560.

48.

BLT1 signalling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophils.

Kojo K, Ito Y, Eshima K, Nishizawa N, Ohkubo H, Yokomizo T, Shimizu T, Watanabe M, Majima M.

Sci Rep. 2016 Jul 11;6:29650. doi: 10.1038/srep29650.

49.

Lack of Phenotypical and Morphological Evidences of Endothelial to Hematopoietic Transition in the Murine Embryonic Head during Hematopoietic Stem Cell Emergence.

Iizuka K, Yokomizo T, Watanabe N, Tanaka Y, Osato M, Takaku T, Komatsu N.

PLoS One. 2016 May 26;11(5):e0156427. doi: 10.1371/journal.pone.0156427. eCollection 2016.

50.

The leukotriene B4 receptor BLT2 protects barrier function via actin polymerization with phosphorylation of myosin phosphatase target subunit 1 in human keratinocytes.

Chiba T, Nakahara T, Hashimoto-Hachiya A, Yokomizo T, Uchi H, Furue M.

Exp Dermatol. 2016 Jul;25(7):532-6. doi: 10.1111/exd.12976. Epub 2016 Apr 15.

PMID:
26896822

Supplemental Content

Loading ...
Support Center