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Achieving greater efficiency and higher confidence in single-cell cloning by combining cell printing and plate imaging technologies.

Yim M, Shaw D.

Biotechnol Prog. 2018 Oct 3. doi: 10.1002/btpr.2698. [Epub ahead of print]


Sargassum serratifolium Extract Attenuates Interleukin-1β-Induced Oxidative Stress and Inflammatory Response in Chondrocytes by Suppressing the Activation of NF-κB, p38 MAPK, and PI3K/Akt.

Park C, Jeong JW, Lee DS, Yim MJ, Lee JM, Han MH, Kim S, Kim HS, Kim GY, Park EK, Jeon YJ, Cha HJ, Choi YH.

Int J Mol Sci. 2018 Aug 7;19(8). pii: E2308. doi: 10.3390/ijms19082308.


Effect of phlorotannins on myofibroblast differentiation and ECM protein expression in transforming growth factor β1‑induced nasal polyp‑derived fibroblasts.

Park J, Choi G, Yim MJ, Lee JM, Yoo JS, Park WS, Park SK, Park S, Seo SK, Kim TG, Lee DS, Choi IW.

Int J Mol Med. 2018 Oct;42(4):2213-2220. doi: 10.3892/ijmm.2018.3770. Epub 2018 Jul 12.


Drug Side-effect Profiles Prediction: From Empirical Risk Minimization to Structural Risk Minimization.

Jiang H, Qiu Y, Hou W, Cheng X, Yim M, Ching WK.

IEEE/ACM Trans Comput Biol Bioinform. 2018 Jun 28. doi: 10.1109/TCBB.2018.2850884. [Epub ahead of print]


Test-retest reliability of the questionnaire in the Sasang constitutional analysis tool (SCAT).

Lee J, Yim MH, Kim JY.

Integr Med Res. 2018 Jun;7(2):136-140. doi: 10.1016/j.imr.2018.02.001. Epub 2018 Feb 10.


Montelukast inhibits RANKL‑induced osteoclast formation and bone loss via CysLTR1 and P2Y12.

Kang JH, Lim H, Lee DS, Yim M.

Mol Med Rep. 2018 Aug;18(2):2387-2398. doi: 10.3892/mmr.2018.9179. Epub 2018 Jun 15.


Alterations of ATP-sensitive K+ channels in human umbilical arterial smooth muscle during gestational diabetes mellitus.

Li H, Shin SE, Seo MS, An JR, Ha KS, Han ET, Hong SH, Kim J, Yim MJ, Lee JM, An TG, Jeon J, Lee SJ, Na SH, Park WS.

Pflugers Arch. 2018 Sep;470(9):1325-1333. doi: 10.1007/s00424-018-2154-8. Epub 2018 May 31.


Subcaudate Tractotomy White Matter Anatomy and Variability: A Diffusion Tensor Imaging Study.

Bhatia KD, Henderson LA, Hsu E, Yim M.

Stereotact Funct Neurosurg. 2018;96(2):71-82. doi: 10.1159/000488359. Epub 2018 May 16.


Blockade of voltage-dependent K+ current in rabbit coronary arterial smooth muscle cells by the tricyclic antidepressant clomipramine.

Li H, Shin SE, An JR, Seo MS, Ha KS, Han ET, Hong SH, Firth AL, Lee DS, Yim MJ, Lee JM, Choi G, Choi IW, Park WS.

J Pharmacol Sci. 2018 May;137(1):61-66. doi: 10.1016/j.jphs.2018.04.005. Epub 2018 Apr 27.


Anti-Inflammatory Potential of Carpomitra costata Ethanolic Extracts via Inhibition of NF-κB and AP-1 Activation in LPS-Stimulated RAW264.7 Macrophages.

Yim MJ, Lee JM, Choi G, Lee DS, Park WS, Jung WK, Park S, Seo SK, Park J, Choi IW, Ma SY.

Evid Based Complement Alternat Med. 2018 Feb 26;2018:6914514. doi: 10.1155/2018/6914514. eCollection 2018.


Reduced integrity of the uncinate fasciculus and cingulum in depression: A stem-by-stem analysis.

Bhatia KD, Henderson LA, Hsu E, Yim M.

J Affect Disord. 2018 Aug 1;235:220-228. doi: 10.1016/j.jad.2018.04.055. Epub 2018 Apr 7.


Ability of novice clinicians to interpret high-resolution optical coherence tomography for ocular surface lesions.

Yim M, Galor A, Nanji A, Joag M, Palioura S, Feuer W, Karp CL.

Can J Ophthalmol. 2018 Apr;53(2):150-154. doi: 10.1016/j.jcjo.2017.08.010. Epub 2017 Nov 28.


IDH2-deficient mice develop spinal deformities with aging.

Chae U, Park NR, Kim ES, Choi JY, Yim M, Lee HS, Lee SR, Lee S, Park JW, Lee DS.

Physiol Res. 2018 Jul 17;67(3):487-494. Epub 2018 Mar 12.


3',4',7,8-Tetrahydroxyflavone inhibits RANKL-induced osteoclast formation and bone resorption.

Kang JH, Jung H, Yim M.

Pharmazie. 2017 Mar 1;72(3):161-166. doi: 10.1691/ph.2017.6845.


The anti-diabetic drug dapagliflozin induces vasodilation via activation of PKG and Kv channels.

Li H, Shin SE, Seo MS, An JR, Choi IW, Jung WK, Firth AL, Lee DS, Yim MJ, Choi G, Lee JM, Na SH, Park WS.

Life Sci. 2018 Mar 15;197:46-55. doi: 10.1016/j.lfs.2018.01.032. Epub 2018 Feb 1.


A Study on the Diagnostic Elements of Cold-Heat Pattern Identification by Korean Medicine Doctors: Association with Objective and Subjective Body Temperature.

Park YJ, Nam JH, Yim MH, Kim H, Kim JY.

Evid Based Complement Alternat Med. 2017;2017:7593056. doi: 10.1155/2017/7593056. Epub 2017 Dec 13.


Diffusion Tensor Imaging Investigation of Uncinate Fasciculus Anatomy in Healthy Controls: Description of a Subgenual Stem.

Bhatia K, Henderson L, Yim M, Hsu E, Dhaliwal R.

Neuropsychobiology. 2017;75(3):132-140. doi: 10.1159/000485111. Epub 2018 Jan 12.


Fexaramine Inhibits Receptor Activator of Nuclear Factor-κB Ligand-induced Osteoclast Formation via Nuclear Factor of Activated T Cells Signaling Pathways.

Zheng T, Kim NY, Yim M.

J Bone Metab. 2017 Nov;24(4):207-215. doi: 10.11005/jbm.2017.24.4.207. Epub 2017 Nov 30.


Probing the importance of clonality: Single cell subcloning of clonally derived CHO cell lines yields widely diverse clones differing in growth, productivity, and product quality.

Ko P, Misaghi S, Hu Z, Zhan D, Tsukuda J, Yim M, Sanford M, Shaw D, Shiratori M, Snedecor B, Laird M, Shen A.

Biotechnol Prog. 2018 May;34(3):624-634. doi: 10.1002/btpr.2594. Epub 2017 Dec 27.


Perception survey on the introduction of clinical performance examination as part of the national nursing licensing examination in Korea.

Shin SJ, Kim YK, Suh SR, Jung DY, Kim Y, Yim MK.

J Educ Eval Health Prof. 2017 Oct 25;14:26. doi: 10.3352/jeehp.2017.14.26. eCollection 2017.


The farnesoid X receptor negatively regulates osteoclastogenesis in bone remodeling and pathological bone loss.

Zheng T, Kang JH, Sim JS, Kim JW, Koh JT, Shin CS, Lim H, Yim M.

Oncotarget. 2017 Aug 28;8(44):76558-76573. doi: 10.18632/oncotarget.20576. eCollection 2017 Sep 29.


Anti-inhibitory potential of an ethanolic extract of Distromium decumbens on pro-inflammatory cytokine production in Pseudomonas aeruginosa lipopolysaccharide-stimulated nasal polyp-derived fibroblasts.

Lee DS, Lee CM, Park SK, Yim MJ, Lee JM, Choi G, Yoo JS, Jung WK, Park S, Seo SK, Park WS, Choi IW.

Int J Mol Med. 2017 Dec;40(6):1950-1956. doi: 10.3892/ijmm.2017.3182. Epub 2017 Oct 11.


Development and characterization of an automated imaging workflow to generate clonally-derived cell lines for therapeutic proteins.

Shaw D, Yim M, Tsukuda J, Joly JC, Lin A, Snedecor B, Laird MW, Lang SE.

Biotechnol Prog. 2018 May;34(3):584-592. doi: 10.1002/btpr.2561. Epub 2017 Oct 10.


Inhibitory effect of the tricyclic antidepressant amitriptyline on voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells.

Li H, Shin SE, Seo MS, An JR, Ha KS, Han ET, Hong SH, Choi IW, Lee DS, Yim MJ, Lee JM, Jung ID, Firth AL, Han IY, Park WS.

Clin Exp Pharmacol Physiol. 2018 Feb;45(2):205-212. doi: 10.1111/1440-1681.12857. Epub 2017 Nov 8.


Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally-derived or not.

Zhou Y, Shaw D, Lam C, Tsukuda J, Yim M, Tang D, Louie S, Laird MW, Snedecor B, Misaghi S.

Biotechnol Prog. 2018 May;34(3):559-569. doi: 10.1002/btpr.2560. Epub 2017 Oct 9.


Evaluating real-time effects of topical 1:1000 epinephrine in endoscopic sinus and skull-base surgery on hemodynamic parameters through intraoperative arterial line monitoring.

Yim MT, Ahmed OG, Takashima M.

Int Forum Allergy Rhinol. 2017 Nov;7(11):1065-1069. doi: 10.1002/alr.22012. Epub 2017 Sep 18.


Stakeholders' Perceptions Sought to Inform the Development of a Low-Cost Mobile Robot for Older Adults: A Qualitative Descriptive Study.

Sefcik JS, Johnson MJ, Yim M, Lau T, Vivio N, Mucchiani C, Cacchione PZ.

Clin Nurs Res. 2018 Feb;27(1):61-80. doi: 10.1177/1054773817730517. Epub 2017 Sep 16.


The vasorelaxant effect of mitiglinide via activation of voltage-dependent K+ channels and SERCA pump in aortic smooth muscle.

Li H, Kim HW, Shin SE, Seo MS, An JR, Ha KS, Han ET, Hong SH, Firth AL, Choi IW, Han IY, Lee DS, Yim MJ, Park WS.

Life Sci. 2017 Nov 1;188:1-9. doi: 10.1016/j.lfs.2017.08.026. Epub 2017 Aug 30.


Smart device-based testing for medical students in Korea: satisfaction, convenience, and advantages.

Lim EY, Yim MK, Huh S.

J Educ Eval Health Prof. 2017 Apr 24;14:7. doi: 10.3352/jeehp.2017.14.7. eCollection 2017.


Supplementation of Nucleosides During Selection can Reduce Sequence Variant Levels in CHO Cells Using GS/MSX Selection System.

Tang D, Lam C, Louie S, Hoi KH, Shaw D, Yim M, Snedecor B, Misaghi S.

Biotechnol J. 2018 Jan;13(1). doi: 10.1002/biot.201700335. Epub 2017 Aug 17.


Pediatric invasive fungal rhinosinusitis: An investigation of 17 patients.

Vinh D, Yim M, Dutta A, Jones JK, Zhang W, Sitton M.

Int J Pediatr Otorhinolaryngol. 2017 Aug;99:111-116. doi: 10.1016/j.ijporl.2017.05.015. Epub 2017 May 25.


Protective effect of zinc preconditioning against renal ischemia reperfusion injury is dose dependent.

Rao K, Sethi K, Ischia J, Gibson L, Galea L, Xiao L, Yim M, Chang M, Papa N, Bolton D, Shulkes A, Baldwin GS, Patel O.

PLoS One. 2017 Jul 7;12(7):e0180028. doi: 10.1371/journal.pone.0180028. eCollection 2017.


Fucoxanthin inhibits profibrotic protein expression in vitro and attenuates bleomycin-induced lung fibrosis in vivo.

Ma SY, Park WS, Lee DS, Choi G, Yim MJ, Lee JM, Jung WK, Park SG, Seo SK, Park SJ, Han IY, Choi YH, Choi IW.

Eur J Pharmacol. 2017 Sep 15;811:199-207. doi: 10.1016/j.ejphar.2017.06.022. Epub 2017 Jun 19.


Depletion of p21-activated kinase 1 up-regulates the immune system of APC∆14/+ mice and inhibits intestinal tumorigenesis.

Huynh N, Wang K, Yim M, Dumesny CJ, Sandrin MS, Baldwin GS, Nikfarjam M, He H.

BMC Cancer. 2017 Jun 19;17(1):431. doi: 10.1186/s12885-017-3432-0.


Induction of p53-Independent Apoptosis and G1 Cell Cycle Arrest by Fucoidan in HCT116 Human Colorectal Carcinoma Cells.

Park HY, Park SH, Jeong JW, Yoon D, Han MH, Lee DS, Choi G, Yim MJ, Lee JM, Kim DH, Kim GY, Choi IW, Kim S, Kim HS, Cha HJ, Choi YH.

Mar Drugs. 2017 May 30;15(6). pii: E154. doi: 10.3390/md15060154.


F4/80 inhibits osteoclast differentiation via downregulation of nuclear factor of activated T cells, cytoplasmic 1.

Kang JH, Sim JS, Zheng T, Yim M.

Arch Pharm Res. 2017 Apr;40(4):492-499. doi: 10.1007/s12272-017-0900-7. Epub 2017 Feb 16.


Evaluation of heavy chain C-terminal deletions on productivity and product quality of monoclonal antibodies in Chinese hamster ovary (CHO) cells.

Hu Z, Tang D, Misaghi S, Jiang G, Yu C, Yim M, Shaw D, Snedecor B, Laird MW, Shen A.

Biotechnol Prog. 2017 May;33(3):786-794. doi: 10.1002/btpr.2444. Epub 2017 Mar 24.


Synthesis and Characterization of β-Tricalcium Phosphate Derived From Haliotis sp. Shells.

Kang KR, Piao ZG, Kim JS, Cho IA, Yim MJ, Kim BH, Oh JS, Son JS, Kim CS, Kim DK, Lee SY, Kim SG.

Implant Dent. 2017 Jun;26(3):378-387. doi: 10.1097/ID.0000000000000559.


Taming hyperactive hDNase I: Stable inducible expression of a hyperactive salt- and actin-resistant variant of human deoxyribonuclease I in CHO cells.

Lam C, Santell L, Wilson B, Yim M, Louie S, Tang D, Shaw D, Chan P, Lazarus RA, Snedecor B, Misaghi S.

Biotechnol Prog. 2017 Mar;33(2):523-533. doi: 10.1002/btpr.2439. Epub 2017 Feb 6.


A review of acute postoperative sialadenitis in children.

Yim MT, Liu YC, Ongkasuwan J.

Int J Pediatr Otorhinolaryngol. 2017 Jan;92:50-55. doi: 10.1016/j.ijporl.2016.11.008. Epub 2016 Nov 12. Review.


FX knockout CHO hosts can express desired ratios of fucosylated or afucosylated antibodies with high titers and comparable product quality.

Louie S, Haley B, Marshall B, Heidersbach A, Yim M, Brozynski M, Tang D, Lam C, Petryniak B, Shaw D, Shim J, Miller A, Lowe JB, Snedecor B, Misaghi S.

Biotechnol Bioeng. 2017 Mar;114(3):632-644. doi: 10.1002/bit.26188. Epub 2016 Oct 4.


Noninvasive Tracking of Encapsulated Insulin Producing Cells Labelled with Magnetic Microspheres by Magnetic Resonance Imaging.

Vaithilingam V, Yim MM, Foster JL, Stait-Gardner T, Oberholzer J, Tuch BE.

J Diabetes Res. 2016;2016:6165893. doi: 10.1155/2016/6165893. Epub 2016 Aug 18.


Incidental radiographic findings of thyroglossal duct cysts: Prevalence and management.

Yim MT, Tran HD, Chandy BM.

Int J Pediatr Otorhinolaryngol. 2016 Oct;89:13-6. doi: 10.1016/j.ijporl.2016.07.024. Epub 2016 Jul 28.


Benzyl isothiocyanate inhibits inflammasome activation in E. coli LPS-stimulated BV2 cells.

Lee CM, Lee DS, Jung WK, Yoo JS, Yim MJ, Choi YH, Park S, Seo SK, Choi JS, Lee YM, Park WS, Choi IW.

Int J Mol Med. 2016 Sep;38(3):912-8. doi: 10.3892/ijmm.2016.2667. Epub 2016 Jul 6.


Investigating B Cell Development, Natural and Primary Antibody Responses in Ly-6A/Sca-1 Deficient Mice.

Jones MA, DeWolf S, Vacharathit V, Yim M, Spencer S, Bamezai AK.

PLoS One. 2016 Jun 20;11(6):e0157271. doi: 10.1371/journal.pone.0157271. eCollection 2016.


PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments.

Nicholls RE, Sontag JM, Zhang H, Staniszewski A, Yan S, Kim CY, Yim M, Woodruff CM, Arning E, Wasek B, Yin D, Bottiglieri T, Sontag E, Kandel ER, Arancio O.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3347-52. doi: 10.1073/pnas.1521018113. Epub 2016 Mar 7.


Studies on antimicrobial activity of Poncirus trifoliata ethyl extract fraction against methicillin-resistant Staphylococcus aureus and to elucidate its antibacterial mechanism.

Eom SH, Jung YJ, Lee DS, Yim MJ, Kim HS, Lee SH, Myeong JI, Lee J, Kim HW, Kim KH, Lee MS, Kim YM.

J Environ Biol. 2016 Jan;37(1):129-34.


Decursin from Angelica gigas suppresses RANKL-induced osteoclast formation and bone loss.

Wang X, Zheng T, Kang JH, Li H, Cho H, Jeon R, Ryu JH, Yim M.

Eur J Pharmacol. 2016 Mar 5;774:34-42. doi: 10.1016/j.ejphar.2016.01.008. Epub 2016 Jan 26.


Anti-allergic effects of a nonameric peptide isolated from the intestine gastrointestinal digests of abalone (Haliotis discus hannai) in activated HMC-1 human mast cells.

Ko SC, Lee DS, Park WS, Yoo JS, Yim MJ, Qian ZJ, Lee CM, Oh J, Jung WK, Choi IW.

Int J Mol Med. 2016 Jan;37(1):243-50. doi: 10.3892/ijmm.2015.2420. Epub 2015 Nov 27.


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