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Items: 1 to 20 of 59

1.

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.

Rheinbay E, Nielsen MM, Abascal F, Wala JA, Shapira O, Tiao G, Hornshøj H, Hess JM, Juul RI, Lin Z, Feuerbach L, Sabarinathan R, Madsen T, Kim J, Mularoni L, Shuai S, Lanzós A, Herrmann C, Maruvka YE, Shen C, Amin SB, Bandopadhayay P, Bertl J, Boroevich KA, Busanovich J, Carlevaro-Fita J, Chakravarty D, Chan CWY, Craft D, Dhingra P, Diamanti K, Fonseca NA, Gonzalez-Perez A, Guo Q, Hamilton MP, Haradhvala NJ, Hong C, Isaev K, Johnson TA, Juul M, Kahles A, Kahraman A, Kim Y, Komorowski J, Kumar K, Kumar S, Lee D, Lehmann KV, Li Y, Liu EM, Lochovsky L, Park K, Pich O, Roberts ND, Saksena G, Schumacher SE, Sidiropoulos N, Sieverling L, Sinnott-Armstrong N, Stewart C, Tamborero D, Tubio JMC, Umer HM, Uusküla-Reimand L, Wadelius C, Wadi L, Yao X, Zhang CZ, Zhang J, Haber JE, Hobolth A, Imielinski M, Kellis M, Lawrence MS, von Mering C, Nakagawa H, Raphael BJ, Rubin MA, Sander C, Stein LD, Stuart JM, Tsunoda T, Wheeler DA, Johnson R, Reimand J, Gerstein M, Khurana E, Campbell PJ, López-Bigas N; PCAWG Drivers and Functional Interpretation Working Group; PCAWG Structural Variation Working Group, Weischenfeldt J, Beroukhim R, Martincorena I, Pedersen JS, Getz G; PCAWG Consortium.

Nature. 2020 Feb;578(7793):102-111. doi: 10.1038/s41586-020-1965-x. Epub 2020 Feb 5.

PMID:
32025015
2.

Patterns of somatic structural variation in human cancer genomes.

Li Y, Roberts ND, Wala JA, Shapira O, Schumacher SE, Kumar K, Khurana E, Waszak S, Korbel JO, Haber JE, Imielinski M; PCAWG Structural Variation Working Group, Weischenfeldt J, Beroukhim R, Campbell PJ; PCAWG Consortium.

Nature. 2020 Feb;578(7793):112-121. doi: 10.1038/s41586-019-1913-9. Epub 2020 Feb 5.

PMID:
32025012
3.

Pan-cancer analysis of whole genomes.

ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium.

Nature. 2020 Feb;578(7793):82-93. doi: 10.1038/s41586-020-1969-6. Epub 2020 Feb 5.

PMID:
32025007
4.

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing.

Cortés-Ciriano I, Lee JJ, Xi R, Jain D, Jung YL, Yang L, Gordenin D, Klimczak LJ, Zhang CZ, Pellman DS; PCAWG Structural Variation Working Group, Park PJ; PCAWG Consortium.

Nat Genet. 2020 Feb 5. doi: 10.1038/s41588-019-0576-7. [Epub ahead of print]

PMID:
32025003
5.

Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer.

Akdemir KC, Le VT, Chandran S, Li Y, Verhaak RG, Beroukhim R, Campbell PJ, Chin L, Dixon JR, Futreal PA; PCAWG Structural Variation Working Group; PCAWG Consortium.

Nat Genet. 2020 Feb 5. doi: 10.1038/s41588-019-0564-y. [Epub ahead of print]

PMID:
32024999
6.

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.

Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F, Demeulemeester J, Santamarina M, Ju YS, Temes J, Garcia-Souto D, Detering H, Li Y, Rodriguez-Castro J, Dueso-Barroso A, Bruzos AL, Dentro SC, Blanco MG, Contino G, Ardeljan D, Tojo M, Roberts ND, Zumalave S, Edwards PAW, Weischenfeldt J, Puiggròs M, Chong Z, Chen K, Lee EA, Wala JA, Raine K, Butler A, Waszak SM, Navarro FCP, Schumacher SE, Monlong J, Maura F, Bolli N, Bourque G, Gerstein M, Park PJ, Wedge DC, Beroukhim R, Torrents D, Korbel JO, Martincorena I, Fitzgerald RC, Van Loo P, Kazazian HH, Burns KH; PCAWG Structural Variation Working Group, Campbell PJ, Tubio JMC; PCAWG Consortium.

Nat Genet. 2020 Feb 5. doi: 10.1038/s41588-019-0562-0. [Epub ahead of print]

PMID:
32024998
7.

High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.

Zhang Y, Chen F, Fonseca NA, He Y, Fujita M, Nakagawa H, Zhang Z, Brazma A; PCAWG Transcriptome Working Group; PCAWG Structural Variation Working Group, Creighton CJ; PCAWG Consortium.

Nat Commun. 2020 Feb 5;11(1):736. doi: 10.1038/s41467-019-13885-w.

8.

Genomic footprints of activated telomere maintenance mechanisms in cancer.

Sieverling L, Hong C, Koser SD, Ginsbach P, Kleinheinz K, Hutter B, Braun DM, Cortés-Ciriano I, Xi R, Kabbe R, Park PJ, Eils R, Schlesner M; PCAWG-Structural Variation Working Group, Brors B, Rippe K, Jones DTW, Feuerbach L; PCAWG Consortium.

Nat Commun. 2020 Feb 5;11(1):733. doi: 10.1038/s41467-019-13824-9.

9.

Cell-in-Cell Phenomenon and Its Relationship With Tumor Microenvironment and Tumor Progression: A Review.

Wang X, Li Y, Li J, Li L, Zhu H, Chen H, Kong R, Wang G, Wang Y, Hu J, Sun B.

Front Cell Dev Biol. 2019 Dec 3;7:311. doi: 10.3389/fcell.2019.00311. eCollection 2019. Review.

10.

High-Performance Wearable Strain Sensor Based on Graphene/Cotton Fabric with High Durability and Low Detection Limit.

Zheng Y, Li Y, Zhou Y, Dai K, Zheng G, Zhang B, Liu C, Shen C.

ACS Appl Mater Interfaces. 2020 Jan 8;12(1):1474-1485. doi: 10.1021/acsami.9b17173. Epub 2019 Dec 24.

PMID:
31825588
11.

Nuomici-Inspired Universal Strategy for Boosting Piezoresistive Sensitivity and Elasticity of Polymer Nanocomposite-Based Strain Sensors.

Ke K, Wang Y, Li Y, Yang J, Pötschke P, Voit B.

ACS Appl Mater Interfaces. 2019 Sep 25;11(38):35362-35370. doi: 10.1021/acsami.9b13510. Epub 2019 Sep 11.

PMID:
31468973
12.

Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer.

Li Y, Kong R, Chen H, Zhao Z, Li L, Li J, Hu J, Zhang G, Pan S, Wang Y, Wang G, Chen H, Sun B.

Aging (Albany NY). 2019 Jul 21;11(14):5035-5057. doi: 10.18632/aging.102096.

13.

UBL4A inhibits autophagy-mediated proliferation and metastasis of pancreatic ductal adenocarcinoma via targeting LAMP1.

Chen H, Li L, Hu J, Zhao Z, Ji L, Cheng C, Zhang G, Zhang T, Li Y, Chen H, Pan S, Sun B.

J Exp Clin Cancer Res. 2019 Jul 9;38(1):297. doi: 10.1186/s13046-019-1278-9.

14.

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nik-Zainal S, Davies H, Staaf J, Ramakrishna M, Glodzik D, Zou X, Martincorena I, Alexandrov LB, Martin S, Wedge DC, Van Loo P, Ju YS, Smid M, Brinkman AB, Morganella S, Aure MR, Lingjærde OC, Langerød A, Ringnér M, Ahn SM, Boyault S, Brock JE, Broeks A, Butler A, Desmedt C, Dirix L, Dronov S, Fatima A, Foekens JA, Gerstung M, Hooijer GKJ, Jang SJ, Jones DR, Kim HY, King TA, Krishnamurthy S, Lee HJ, Lee JY, Li Y, McLaren S, Menzies A, Mustonen V, O'Meara S, Pauporté I, Pivot X, Purdie CA, Raine K, Ramakrishnan K, Rodríguez-González FG, Romieu G, Sieuwerts AM, Simpson PT, Shepherd R, Stebbings L, Stefansson OA, Teague J, Tommasi S, Treilleux I, Van den Eynden GG, Vermeulen P, Vincent-Salomon A, Yates L, Caldas C, Van't Veer L, Tutt A, Knappskog S, Tan BKT, Jonkers J, Borg Å, Ueno NT, Sotiriou C, Viari A, Futreal PA, Campbell PJ, Span PN, Van Laere S, Lakhani SR, Eyfjord JE, Thompson AM, Birney E, Stunnenberg HG, van de Vijver MJ, Martens JWM, Børresen-Dale AL, Richardson AL, Kong G, Thomas G, Stratton MR.

Nature. 2019 Feb;566(7742):E1. doi: 10.1038/s41586-019-0883-2.

PMID:
30659290
15.

Fast and accurate genomic analyses using genome graphs.

Rakocevic G, Semenyuk V, Lee WP, Spencer J, Browning J, Johnson IJ, Arsenijevic V, Nadj J, Ghose K, Suciu MC, Ji SG, Demir G, Li L, Toptaş BÇ, Dolgoborodov A, Pollex B, Spulber I, Glotova I, Kómár P, Stachyra AL, Li Y, Popovic M, Källberg M, Jain A, Kural D.

Nat Genet. 2019 Feb;51(2):354-362. doi: 10.1038/s41588-018-0316-4. Epub 2019 Jan 14.

PMID:
30643257
16.

Yolk-Shell-Mesostructured Silica-Supported Dual Molecular Catalyst for Enantioselective Tandem Reactions.

Wu L, Li Y, Meng J, Jin R, Lin J, Liu G.

Chempluschem. 2018 Sep;83(9):861-867. doi: 10.1002/cplu.201800377.

PMID:
31950681
17.

MiR-361-3p regulates ERK1/2-induced EMT via DUSP2 mRNA degradation in pancreatic ductal adenocarcinoma.

Hu J, Li L, Chen H, Zhang G, Liu H, Kong R, Chen H, Wang Y, Li Y, Tian F, Lv X, Li G, Sun B.

Cell Death Dis. 2018 Jul 24;9(8):807. doi: 10.1038/s41419-018-0839-8.

18.

Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.

Bolli N, Biancon G, Moarii M, Gimondi S, Li Y, de Philippis C, Maura F, Sathiaseelan V, Tai YT, Mudie L, O'Meara S, Raine K, Teague JW, Butler AP, Carniti C, Gerstung M, Bagratuni T, Kastritis E, Dimopoulos M, Corradini P, Anderson KC, Moreau P, Minvielle S, Campbell PJ, Papaemmanuil E, Avet-Loiseau H, Munshi NC.

Leukemia. 2018 Dec;32(12):2604-2616. doi: 10.1038/s41375-018-0037-9. Epub 2018 May 22.

19.

Author Correction: Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries.

Ong SH, Li Y, Koike-Yusa H, Yusa K.

Sci Rep. 2018 Apr 12;8(1):6136. doi: 10.1038/s41598-018-24092-w.

20.

SvABA: genome-wide detection of structural variants and indels by local assembly.

Wala JA, Bandopadhayay P, Greenwald NF, O'Rourke R, Sharpe T, Stewart C, Schumacher S, Li Y, Weischenfeldt J, Yao X, Nusbaum C, Campbell P, Getz G, Meyerson M, Zhang CZ, Imielinski M, Beroukhim R.

Genome Res. 2018 Apr;28(4):581-591. doi: 10.1101/gr.221028.117. Epub 2018 Mar 13.

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