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Items: 1 to 20 of 48

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1.

Unbiased transcriptomic analyses reveal distinct effects of immune deficiency in CNS function with and without injury.

Luo D, Ge W, Hu X, Li C, Lee CM, Zhou L, Wu Z, Yu J, Lin S, Yu J, Xu W, Chen L, Zhang C, Jiang K, Zhu X, Li H, Gao X, Geng Y, Jing B, Wang Z, Zheng C, Zhu R, Yan Q, Lin Q, Ye K, Sun YE, Cheng L.

Protein Cell. 2018 Jun 28. doi: 10.1007/s13238-018-0559-y. [Epub ahead of print]

PMID:
29956125
2.

TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson's disease.

Kang SS, Zhang Z, Liu X, Manfredsson FP, Benskey MJ, Cao X, Xu J, Sun YE, Ye K.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10773-10778. doi: 10.1073/pnas.1713969114. Epub 2017 Sep 18.

3.

MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life.

Lin Q, Ponnusamy R, Widagdo J, Choi JA, Ge W, Probst C, Buckley T, Lou M, Bredy TW, Fanselow MS, Ye K, Sun YE.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9188-9193. doi: 10.1073/pnas.1706069114. Epub 2017 Aug 8.

4.

Single-cell transcriptomics reveals gene signatures and alterations associated with aging in distinct neural stem/progenitor cell subpopulations.

Shi Z, Geng Y, Liu J, Zhang H, Zhou L, Lin Q, Yu J, Zhang K, Liu J, Gao X, Zhang C, Yao Y, Zhang C, Sun YE.

Protein Cell. 2018 Apr;9(4):351-364. doi: 10.1007/s13238-017-0450-2. Epub 2017 Jul 26.

5.

Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease.

Zhang Z, Kang SS, Liu X, Ahn EH, Zhang Z, He L, Iuvone PM, Duong DM, Seyfried NT, Benskey MJ, Manfredsson FP, Jin L, Sun YE, Wang JZ, Ye K.

Nat Struct Mol Biol. 2017 Aug;24(8):632-642. doi: 10.1038/nsmb.3433. Epub 2017 Jul 3.

6.

α-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation.

Kang SS, Zhang Z, Liu X, Manfredsson FP, He L, Iuvone PM, Cao X, Sun YE, Jin L, Ye K.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1183-1188. doi: 10.1073/pnas.1618627114. Epub 2017 Jan 17.

7.

Coupled electrophysiological recording and single cell transcriptome analyses revealed molecular mechanisms underlying neuronal maturation.

Chen X, Zhang K, Zhou L, Gao X, Wang J, Yao Y, He F, Luo Y, Yu Y, Li S, Cheng L, Sun YE.

Protein Cell. 2016 Mar;7(3):175-86. doi: 10.1007/s13238-016-0247-8. Epub 2016 Feb 16.

8.

Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease.

Zhang Z, Song M, Liu X, Su Kang S, Duong DM, Seyfried NT, Cao X, Cheng L, Sun YE, Ping Yu S, Jia J, Levey AI, Ye K.

Nat Commun. 2015 Nov 9;6:8762. doi: 10.1038/ncomms9762.

9.

Transcriptome analyses reveal molecular mechanisms underlying functional recovery after spinal cord injury.

Duan H, Ge W, Zhang A, Xi Y, Chen Z, Luo D, Cheng Y, Fan KS, Horvath S, Sofroniew MV, Cheng L, Yang Z, Sun YE, Li X.

Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13360-5. doi: 10.1073/pnas.1510176112. Epub 2015 Oct 12.

10.

NT3-chitosan elicits robust endogenous neurogenesis to enable functional recovery after spinal cord injury.

Yang Z, Zhang A, Duan H, Zhang S, Hao P, Ye K, Sun YE, Li X.

Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13354-9. doi: 10.1073/pnas.1510194112. Epub 2015 Oct 12.

11.

Circadian rhythm disruption in a mouse model of Rett syndrome circadian disruption in RTT.

Li Q, Loh DH, Kudo T, Truong D, Derakhshesh M, Kaswan ZM, Ghiani CA, Tsoa R, Cheng Y, Sun YE, Colwell CS.

Neurobiol Dis. 2015 May;77:155-64. doi: 10.1016/j.nbd.2015.03.009. Epub 2015 Mar 14.

PMID:
25779967
12.

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.

Zhang Z, Song M, Liu X, Kang SS, Kwon IS, Duong DM, Seyfried NT, Hu WT, Liu Z, Wang JZ, Cheng L, Sun YE, Yu SP, Levey AI, Ye K.

Nat Med. 2014 Nov;20(11):1254-62. doi: 10.1038/nm.3700. Epub 2014 Oct 19.

13.

Spatiotemporally different origins of NG2 progenitors produce cortical interneurons versus glia in the mammalian forebrain.

Tsoa RW, Coskun V, Ho CK, de Vellis J, Sun YE.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7444-9. doi: 10.1073/pnas.1400422111. Epub 2014 May 5.

14.

Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward.

Cui Y, Ostlund SB, James AS, Park CS, Ge W, Roberts KW, Mittal N, Murphy NP, Cepeda C, Kieffer BL, Levine MS, Jentsch JD, Walwyn WM, Sun YE, Evans CJ, Maidment NT, Yang XW.

Nat Neurosci. 2014 Feb;17(2):254-61. doi: 10.1038/nn.3622. Epub 2014 Jan 12.

15.

Genetic modification of mesenchymal stem cells in spinal cord injury repair strategies.

Cui X, Chen L, Ren Y, Ji Y, Liu W, Liu J, Yan Q, Cheng L, Sun YE.

Biosci Trends. 2013 Oct;7(5):202-8.

17.

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.

Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, Diner I, Heilman CJ, Rees HD, Wu H, Lin L, Szulwach KE, Gearing M, Mufson EJ, Bennett DA, Montine TJ, Seyfried NT, Wingo TS, Sun YE, Jin P, Hanfelt J, Willcock DM, Levey A, Lah JJ, Peng J.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16562-7. doi: 10.1073/pnas.1310249110. Epub 2013 Sep 10.

18.

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing.

Xue Z, Huang K, Cai C, Cai L, Jiang CY, Feng Y, Liu Z, Zeng Q, Cheng L, Sun YE, Liu JY, Horvath S, Fan G.

Nature. 2013 Aug 29;500(7464):593-7. doi: 10.1038/nature12364. Epub 2013 Jul 28.

19.

Identification of miRNA signatures during the differentiation of hESCs into retinal pigment epithelial cells.

Hu G, Huang K, Yu J, Gopalakrishna-Pillai S, Kong J, Xu H, Liu Z, Zhang K, Xu J, Luo Y, Li S, Sun YE, Iverson LE, Xue Z, Fan G.

PLoS One. 2012;7(7):e37224. doi: 10.1371/journal.pone.0037224. Epub 2012 Jul 27.

20.

Epigenetic regulation of stem cells differentiating along the neural lineage.

Coskun V, Tsoa R, Sun YE.

Curr Opin Neurobiol. 2012 Oct;22(5):762-7. doi: 10.1016/j.conb.2012.07.001. Epub 2012 Jul 24. Review.

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