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Nuclei multiplexing with barcoded antibodies for single-nucleus genomics.

Gaublomme JT, Li B, McCabe C, Knecht A, Yang Y, Drokhlyansky E, Van Wittenberghe N, Waldman J, Dionne D, Nguyen L, De Jager PL, Yeung B, Zhao X, Habib N, Rozenblatt-Rosen O, Regev A.

Nat Commun. 2019 Jul 2;10(1):2907. doi: 10.1038/s41467-019-10756-2.



Hammi C, Yeung B.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Jun 4.


Trigger Point Injection.

Hammi C, Yeung B.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Jun 2.


Hepatic spheroids used as an in vitro model to study malaria relapse.

Chua ACY, Ananthanarayanan A, Ong JJY, Wong JY, Yip A, Singh NH, Qu Y, Dembele L, McMillian M, Ubalee R, Davidson S, Tungtaeng A, Imerbsin R, Gupta K, Andolina C, Lee F, S-W Tan K, Nosten F, Russell B, Lange A, Diagana TT, Rénia L, Yeung BKS, Yu H, Bifani P.

Biomaterials. 2019 Sep;216:119221. doi: 10.1016/j.biomaterials.2019.05.032. Epub 2019 May 22.


Identification of Prolyl isomerase Pin1 as a novel positive regulator of YAP/TAZ in breast cancer cells.

Khanal P, Yeung B, Zhao Y, Yang X.

Sci Rep. 2019 Apr 23;9(1):6394. doi: 10.1038/s41598-019-42767-w.


Cell Hashing with barcoded antibodies enables multiplexing and doublet detection for single cell genomics.

Stoeckius M, Zheng S, Houck-Loomis B, Hao S, Yeung BZ, Mauck WM 3rd, Smibert P, Satija R.

Genome Biol. 2018 Dec 19;19(1):224. doi: 10.1186/s13059-018-1603-1.


Population-level effectiveness of rapid, targeted, high-coverage roll-out of HIV pre-exposure prophylaxis in men who have sex with men: the EPIC-NSW prospective cohort study.

Grulich AE, Guy R, Amin J, Jin F, Selvey C, Holden J, Schmidt HA, Zablotska I, Price K, Whittaker B, Chant K, Cooper C, McGill S, Telfer B, Yeung B, Levitt G, Ogilvie EE, Dharan NJ, Hammoud MA, Vaccher S, Watchirs-Smith L, McNulty A, Smith DJ, Allen DM, Baker D, Bloch M, Bopage RI, Brown K, Carr A, Carmody CJ, Collins KL, Finlayson R, Foster R, Jackson EY, Lewis DA, Lusk J, O'Connor CC, Ryder N, Vlahakis E, Read P, Cooper DA; Expanded PrEP Implementation in Communities New South Wales (EPIC-NSW) research group.

Lancet HIV. 2018 Nov;5(11):e629-e637. doi: 10.1016/S2352-3018(18)30215-7. Epub 2018 Oct 17.


Prevalence and Correlates of Reporting Difficulty Taking Antiretroviral Treatment Among HIV-Positive Illicit Drug Users in Vancouver, Canada: A Longitudinal Analysis.

Yeung B, Mohd Salleh NA, Socías E, Dong H, Shoveller J, Montaner JSG, Milloy MS.

AIDS Behav. 2019 May;23(5):1250-1257. doi: 10.1007/s10461-018-2271-6.


Endoscopic therapy for upper gastrointestinal bleeding: less is more?

Yeung BPM, Craig C, Morris J, Christie A, Kasthuri R, Stuart W, Stanley AJ.

Frontline Gastroenterol. 2018 Jul;9(3):208-209. doi: 10.1136/flgastro-2017-100911. Epub 2018 Jan 23. No abstract available.


Recovery of "Lost" Infant Memories in Mice.

Guskjolen A, Kenney JW, de la Parra J, Yeung BA, Josselyn SA, Frankland PW.

Curr Biol. 2018 Jul 23;28(14):2283-2290.e3. doi: 10.1016/j.cub.2018.05.059. Epub 2018 Jul 5.


A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.

Azad T, Janse van Rensburg HJ, Lightbody ED, Neveu B, Champagne A, Ghaffari A, Kay VR, Hao Y, Shen H, Yeung B, Croy BA, Guan KL, Pouliot F, Zhang J, Nicol CJB, Yang X.

Nat Commun. 2018 Mar 13;9(1):1061. doi: 10.1038/s41467-018-03278-w.


Identification of Cdk1-LATS-Pin1 as a Novel Signaling Axis in Anti-tubulin Drug Response of Cancer Cells.

Yeung B, Khanal P, Mehta V, Trinkle-Mulcahy L, Yang X.

Mol Cancer Res. 2018 Jun;16(6):1035-1045. doi: 10.1158/1541-7786.MCR-17-0684. Epub 2018 Mar 9.


Quantitative contributions of processes by which polyanion drugs reduce intracellular bioavailability and transfection efficiency of cationic siRNA lipoplex.

Jaiprasart P, Yeung BZ, Lu Z, Wientjes MG, Cui M, Hsieh CM, Woo S, Au JL.

J Control Release. 2018 Jan 28;270:101-113. doi: 10.1016/j.jconrel.2017.12.001. Epub 2017 Dec 22.


Exosome is a mechanism of intercellular drug transfer: Application of quantitative pharmacology.

Wang J, Yeung BZ, Cui M, Peer CJ, Lu Z, Figg WD, Guillaume Wientjes M, Woo S, Au JL.

J Control Release. 2017 Dec 28;268:147-158. doi: 10.1016/j.jconrel.2017.10.020. Epub 2017 Oct 18.


Strict tropism for CD71+/CD234+ human reticulocytes limits the zoonotic potential of Plasmodium cynomolgi.

Kosaisavee V, Suwanarusk R, Chua ACY, Kyle DE, Malleret B, Zhang R, Imwong M, Imerbsin R, Ubalee R, Sámano-Sánchez H, Yeung BKS, Ong JJY, Lombardini E, Nosten F, Tan KSW, Bifani P, Snounou G, Rénia L, Russell B.

Blood. 2017 Sep 14;130(11):1357-1363. doi: 10.1182/blood-2017-02-764787. Epub 2017 Jul 11.


Endoscopic removal of an eroded magnetic sphincter augmentation device.

Yeung BPM, Fullarton G.

Endoscopy. 2017 Jul;49(7):718-719. doi: 10.1055/s-0043-109236. Epub 2017 May 30. No abstract available.


The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites.

Dembele L, Ang X, Chavchich M, Bonamy GMC, Selva JJ, Lim MY, Bodenreider C, Yeung BKS, Nosten F, Russell BM, Edstein MD, Straimer J, Fidock DA, Diagana TT, Bifani P.

Sci Rep. 2017 May 24;7(1):2325. doi: 10.1038/s41598-017-02440-6.


Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit.

Kounde CS, Yeo HQ, Wang QY, Wan KF, Dong H, Karuna R, Dix I, Wagner T, Zou B, Simon O, Bonamy GMC, Yeung BKS, Yokokawa F.

Bioorg Med Chem Lett. 2017 Mar 15;27(6):1385-1389. doi: 10.1016/j.bmcl.2017.02.005. Epub 2017 Feb 4.


DDW 2016 review: Advances in therapeutic upper gastrointestinal endoscopy.

Chan SM, Yeung B, Chiu PW.

Dig Endosc. 2017 Mar;29(2):145-148. doi: 10.1111/den.12767. Epub 2017 Jan 22. Review.


An innovative ex-vivo porcine upper gastrointestinal model for submucosal tunnelling endoscopic resection (STER).

Yeung B, Chiu P, Teoh A, Zheng L, Chan S, Lam K, Tang R, Ng EK.

Endosc Int Open. 2016 Oct;4(10):E1101-E1106. Epub 2016 Sep 14.


UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes.

Lim MY, LaMonte G, Lee MCS, Reimer C, Tan BH, Corey V, Tjahjadi BF, Chua A, Nachon M, Wintjens R, Gedeck P, Malleret B, Renia L, Bonamy GMC, Ho PC, Yeung BKS, Chow ED, Lim L, Fidock DA, Diagana TT, Winzeler EA, Bifani P.

Nat Microbiol. 2016 Sep 19;1:16166. doi: 10.1038/nmicrobiol.2016.166.


Short duration response-guided treatment is effective for most individuals with recent hepatitis C infection: the ATAHC II and DARE-C I studies.

Martinello M, Hellard M, Shaw D, Petoumenos K, Applegate T, Grebely J, Yeung B, Maire L, Iser D, Lloyd A, Thompson A, Sasadeusz J, Haber P, Dore GJ, Matthews GV.

Antivir Ther. 2016;21(5):465. doi: 10.3851/IMP3073. Epub 2016 Aug 10. No abstract available.


Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance.

LaMonte G, Lim MY, Wree M, Reimer C, Nachon M, Corey V, Gedeck P, Plouffe D, Du A, Figueroa N, Yeung B, Bifani P, Winzeler EA.

MBio. 2016 Jul 5;7(4). pii: e00696-16. doi: 10.1128/mBio.00696-16.


Endoscopic Management of Gallbladder Stones: Can We Eliminate Cholecystectomy?

Yeung B, Teoh AY.

Curr Gastroenterol Rep. 2016 Aug;18(8):42. doi: 10.1007/s11894-016-0518-9. Review.


Subacute food bolus obstruction secondary to a migrated Overstitch suture from a previous esophageal perforation repair.

Yeung BP, Chan SM, Chiu PW.

Endoscopy. 2016;48 Suppl 1:E177-8. doi: 10.1055/s-0042-106965. Epub 2016 May 23. No abstract available.


Re: Early postoperative outcome of bipolar transurethral enucleation and resection of the prostate.

Yeung B.

Hong Kong Med J. 2016 Apr;22(2):188. doi: 10.12809/hkmj164831. No abstract available.


PI4 Kinase Is a Prophylactic but Not Radical Curative Target in Plasmodium vivax-Type Malaria Parasites.

Zeeman AM, Lakshminarayana SB, van der Werff N, Klooster EJ, Voorberg-van der Wel A, Kondreddi RR, Bodenreider C, Simon O, Sauerwein R, Yeung BK, Diagana TT, Kocken CH.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):2858-63. doi: 10.1128/AAC.03080-15. Print 2016 May.


Short duration response-guided treatment is effective for most individuals with recent hepatitis C infection: the ATAHC II and DARE-C I studies.

Martinello M, Hellard M, Shaw D, Petoumenos K, Applegate T, Grebely J, Yeung B, Maire L, Iser D, Lloyd A, Thompson A, Sasadeusz J, Haber P, Dore GJ, Matthews GV.

Antivir Ther. 2016;21(5):425-34. doi: 10.3851/IMP3035. Epub 2016 Feb 11.


Application of robotics in gastrointestinal endoscopy: A review.

Yeung BP, Chiu PW.

World J Gastroenterol. 2016 Feb 7;22(5):1811-25. doi: 10.3748/wjg.v22.i5.1811. Review.


Delivery of cancer therapeutics to extracellular and intracellular targets: Determinants, barriers, challenges and opportunities.

Au JL, Yeung BZ, Wientjes MG, Lu Z, Wientjes MG.

Adv Drug Deliv Rev. 2016 Feb 1;97:280-301. doi: 10.1016/j.addr.2015.12.002. Epub 2015 Dec 11. Review.


Stanniocalcin-1 Reduces Tumor Size in Human Hepatocellular Carcinoma.

Yeung BH, Shek FH, Lee NP, Wong CK.

PLoS One. 2015 Oct 15;10(10):e0139977. doi: 10.1371/journal.pone.0139977. eCollection 2015.


High Sensitivity RT-qPCR Assay of Nonlabeled siRNA in Small Blood Volume for Pharmacokinetic Studies: Application to Survivin siRNA.

Yeung BZ, Lu Z, Wientjes GM, Au JL.

AAPS J. 2015 Nov;17(6):1475-82. doi: 10.1208/s12248-015-9812-y. Epub 2015 Aug 19.


Paclitaxel tumor priming promotes delivery and transfection of intravenous lipid-siRNA in pancreatic tumors.

Wang J, Lu Z, Wang J, Cui M, Yeung BZ, Cole DJ, Wientjes MG, Au JL.

J Control Release. 2015 Oct 28;216:103-10. doi: 10.1016/j.jconrel.2015.08.012. Epub 2015 Aug 10.


Injecting risk behaviours following treatment for hepatitis C virus infection among people who inject drugs: The Australian Trial in Acute Hepatitis C.

Alavi M, Spelman T, Matthews GV, Haber PS, Day C, van Beek I, Walsh N, Yeung B, Bruneau J, Petoumenos K, Dolan K, Kaldor JM, Dore GJ, Hellard M, Grebely J; ATAHC Study Group.

Int J Drug Policy. 2015 Oct;26(10):976-83. doi: 10.1016/j.drugpo.2015.05.003. Epub 2015 May 21.


Drug discovery for the developing world: progress at the Novartis Institute for Tropical Diseases.

Jones CL, Yeung BK, Manjunatha U, Shi PY, Bodenreider C, Diagana TT.

Nat Rev Drug Discov. 2015 Jun;14(6):442-4. doi: 10.1038/nrd4001-c1. No abstract available.


Characterization of stanniocalcin 1 binding and signaling in gill cells of Japanese eels.

Gu J, Law AY, Yeung BH, Wong CK.

J Mol Endocrinol. 2015 Jun;54(3):305-14. doi: 10.1530/JME-14-0320. Epub 2015 Apr 15.


Roles of the Hippo pathway in lung development and tumorigenesis.

Yeung B, Yu J, Yang X.

Int J Cancer. 2016 Feb 1;138(3):533-9. doi: 10.1002/ijc.29457. Epub 2015 Feb 21. Review.


Capillary zone electrophoresis method for a highly glycosylated and sialylated recombinant protein: development, characterization and application for process development.

Zhang L, Lawson K, Yeung B, Wypych J.

Anal Chem. 2015 Jan 6;87(1):470-6. doi: 10.1021/ac504187v. Epub 2014 Dec 18.


Pharmacokinetic-pharmacodynamic analysis of spiroindolone analogs and KAE609 in a murine malaria model.

Lakshminarayana SB, Freymond C, Fischli C, Yu J, Weber S, Goh A, Yeung BK, Ho PC, Dartois V, Diagana TT, Rottmann M, Blasco F.

Antimicrob Agents Chemother. 2015 Feb;59(2):1200-10. doi: 10.1128/AAC.03274-14. Epub 2014 Dec 8.


Pharmacodynamics of telomerase inhibition and telomere shortening by noncytotoxic suramin.

Gan Y, Lu J, Yeung BZ, Cottage CT, Wientjes MG, Au JL.

AAPS J. 2015 Jan;17(1):268-76. doi: 10.1208/s12248-014-9703-7. Epub 2014 Nov 26.


Activation of gill Ca2+-sensing receptor as a protective pathway to reduce Ca2+-induced cytotoxicity.

Gu J, Law AY, Yeung BH, Wong CK.

J Mol Endocrinol. 2014 Oct;53(2):155-64. doi: 10.1530/JME-14-0060.


Lead optimization of imidazopyrazines: a new class of antimalarial with activity on Plasmodium liver stages.

Zou B, Nagle A, Chatterjee AK, Leong SY, Tan LJ, Sim WL, Mishra P, Guntapalli P, Tully DC, Lakshminarayana SB, Lim CS, Tan YC, Abas SN, Bodenreider C, Kuhen KL, Gagaring K, Borboa R, Chang J, Li C, Hollenbeck T, Tuntland T, Zeeman AM, Kocken CH, McNamara C, Kato N, Winzeler EA, Yeung BK, Diagana TT, Smith PW, Roland J.

ACS Med Chem Lett. 2014 Jul 6;5(8):947-50. doi: 10.1021/ml500244m. eCollection 2014 Aug 14.


Predicting diffusive transport of cationic liposomes in 3-dimensional tumor spheroids.

Wientjes MG, Yeung BZ, Lu Z, Wientjes MG, Au JL.

J Control Release. 2014 Oct 28;192:10-8. doi: 10.1016/j.jconrel.2014.06.050. Epub 2014 Jul 2.


Tumor priming enhances siRNA delivery and transfection in intraperitoneal tumors.

Wang J, Lu Z, Yeung BZ, Wientjes MG, Cole DJ, Au JL.

J Control Release. 2014 Mar 28;178:79-85. doi: 10.1016/j.jconrel.2014.01.012. Epub 2014 Jan 23.


Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays.

Escher BI, Allinson M, Altenburger R, Bain PA, Balaguer P, Busch W, Crago J, Denslow ND, Dopp E, Hilscherova K, Humpage AR, Kumar A, Grimaldi M, Jayasinghe BS, Jarosova B, Jia A, Makarov S, Maruya KA, Medvedev A, Mehinto AC, Mendez JE, Poulsen A, Prochazka E, Richard J, Schifferli A, Schlenk D, Scholz S, Shiraishi F, Snyder S, Su G, Tang JY, van der Burg B, van der Linden SC, Werner I, Westerheide SD, Wong CK, Yang M, Yeung BH, Zhang X, Leusch FD.

Environ Sci Technol. 2014;48(3):1940-56. doi: 10.1021/es403899t. Epub 2013 Dec 26.


KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro.

Zeeman AM, van Amsterdam SM, McNamara CW, Voorberg-van der Wel A, Klooster EJ, van den Berg A, Remarque EJ, Plouffe DM, van Gemert GJ, Luty A, Sauerwein R, Gagaring K, Borboa R, Chen Z, Kuhen K, Glynne RJ, Chatterjee AK, Nagle A, Roland J, Winzeler EA, Leroy D, Campo B, Diagana TT, Yeung BK, Thomas AW, Kocken CH.

Antimicrob Agents Chemother. 2014;58(3):1586-95. doi: 10.1128/AAC.01927-13. Epub 2013 Dec 23.


Targeting Plasmodium PI(4)K to eliminate malaria.

McNamara CW, Lee MC, Lim CS, Lim SH, Roland J, Simon O, Yeung BK, Chatterjee AK, McCormack SL, Manary MJ, Zeeman AM, Dechering KJ, Kumar TS, Henrich PP, Gagaring K, Ibanez M, Kato N, Kuhen KL, Fischli C, Nagle A, Rottmann M, Plouffe DM, Bursulaya B, Meister S, Rameh L, Trappe J, Haasen D, Timmerman M, Sauerwein RW, Suwanarusk R, Russell B, Renia L, Nosten F, Tully DC, Kocken CH, Glynne RJ, Bodenreider C, Fidock DA, Diagana TT, Winzeler EA.

Nature. 2013 Dec 12;504(7479):248-253. doi: 10.1038/nature12782. Epub 2013 Nov 27.


Plasma interferon-gamma-inducible protein-10 levels are associated with early, but not sustained virological response during treatment of acute or early chronic HCV infection.

Feld JJ, Grebely J, Matthews GV, Applegate T, Hellard M, Sherker A, Cherepanov V, Petoumenos K, Yeung B, Kaldor JM, Lloyd AR, Dore GJ.

PLoS One. 2013 Nov 20;8(11):e80003. doi: 10.1371/journal.pone.0080003. eCollection 2013.


Insulin activates the insulin receptor to downregulate the PTEN tumour suppressor.

Liu J, Visser-Grieve S, Boudreau J, Yeung B, Lo S, Chamberlain G, Yu F, Sun T, Papanicolaou T, Lam A, Yang X, Chin-Sang I.

Oncogene. 2014 Jul 17;33(29):3878-85. doi: 10.1038/onc.2013.347. Epub 2013 Sep 2.


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