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Items: 15


Limitations of Murine Models for Assessment of Antibody-Mediated Therapies or Vaccine Candidates against Staphylococcus epidermidis Bloodstream Infection.

Cole LE, Zhang J, Kesselly A, Anosova NG, Lam H, Kleanthous H, Yethon JA.

Infect Immun. 2016 Mar 24;84(4):1143-1149. doi: 10.1128/IAI.01472-15. Print 2016 Apr.


VACCINES. A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells.

Stary G, Olive A, Radovic-Moreno AF, Gondek D, Alvarez D, Basto PA, Perro M, Vrbanac VD, Tager AM, Shi J, Yethon JA, Farokhzad OC, Langer R, Starnbach MN, von Andrian UH.

Science. 2015 Jun 19;348(6241):aaa8205. doi: 10.1126/science.aaa8205.


Correction for Lam et al., antibodies to PhnD inhibit staphylococcal biofilms.

Lam H, Kesselly A, Stegalkina S, Charlebois RL, Oomen R, Kleanthous H, Yethon JA.

Infect Immun. 2015 May;83(5):2197. doi: 10.1128/IAI.00285-15. No abstract available.


Antibodies to PhnD inhibit staphylococcal biofilms.

Lam H, Kesselly A, Stegalkina S, Kleanthous H, Yethon JA.

Infect Immun. 2014 Sep;82(9):3764-74. doi: 10.1128/IAI.02168-14. Epub 2014 Jun 23. Erratum in: Infect Immun. 2015 May;83(5):2197.


Structure-guided antigen engineering yields pneumolysin mutants suitable for vaccination against pneumococcal disease.

Oloo EO, Yethon JA, Ochs MM, Carpick B, Oomen R.

J Biol Chem. 2011 Apr 8;286(14):12133-40. doi: 10.1074/jbc.M110.191148. Epub 2011 Feb 4.


There is more to life and death than mitochondria: Bcl-2 proteins at the endoplasmic reticulum.

Annis MG, Yethon JA, Leber B, Andrews DW.

Biochim Biophys Acta. 2004 Mar 1;1644(2-3):115-23. Review.


Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis.

Yethon JA, Epand RF, Leber B, Epand RM, Andrews DW.

J Biol Chem. 2003 Dec 5;278(49):48935-41. Epub 2003 Sep 30.


Lipopolysaccharide as a target for the development of novel therapeutics in gram-negative bacteria.

Yethon JA, Whitfield C.

Curr Drug Targets Infect Disord. 2001 Aug;1(2):91-106. Review.


Salmonella enterica serovar typhimurium waaP mutants show increased susceptibility to polymyxin and loss of virulence In vivo.

Yethon JA, Gunn JS, Ernst RK, Miller SI, Laroche L, Malo D, Whitfield C.

Infect Immun. 2000 Aug;68(8):4485-91.


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