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Items: 1 to 50 of 125

1.

Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease.

Sommer A, Marxreiter F, Krach F, Fadler T, Grosch J, Maroni M, Graef D, Eberhardt E, Riemenschneider MJ, Yeo GW, Kohl Z, Xiang W, Gage FH, Winkler J, Prots I, Winner B.

Cell Stem Cell. 2019 Jun 6;24(6):1006. doi: 10.1016/j.stem.2019.04.019. No abstract available.

PMID:
31173705
2.

Active Protein Neddylation or Ubiquitylation Is Dispensable for Stress Granule Dynamics.

Markmiller S, Fulzele A, Higgins R, Leonard M, Yeo GW, Bennett EJ.

Cell Rep. 2019 Apr 30;27(5):1356-1363.e3. doi: 10.1016/j.celrep.2019.04.015.

3.

Disruption in A-to-I Editing Levels Affects C. elegans Development More Than a Complete Lack of Editing.

Ganem NS, Ben-Asher N, Manning AC, Deffit SN, Washburn MC, Wheeler EC, Yeo GW, Zgayer OB, Mantsur E, Hundley HA, Lamm AT.

Cell Rep. 2019 Apr 23;27(4):1244-1253.e4. doi: 10.1016/j.celrep.2019.03.095.

4.

Disruption of RNA Metabolism in Neurological Diseases and Emerging Therapeutic Interventions.

Nussbacher JK, Tabet R, Yeo GW, Lagier-Tourenne C.

Neuron. 2019 Apr 17;102(2):294-320. doi: 10.1016/j.neuron.2019.03.014. Review.

5.

Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA.

Yang EW, Bahn JH, Hsiao EY, Tan BX, Sun Y, Fu T, Zhou B, Van Nostrand EL, Pratt GA, Freese P, Wei X, Quinones-Valdez G, Urban AE, Graveley BR, Burge CB, Yeo GW, Xiao X.

Nat Commun. 2019 Mar 22;10(1):1338. doi: 10.1038/s41467-019-09292-w.

6.

Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal.

Gould TW, Dominguez B, de Winter F, Yeo GW, Liu P, Sundararaman B, Stark T, Vu A, Degen JL, Lin W, Lee KF.

PLoS Genet. 2019 Mar 14;15(3):e1007948. doi: 10.1371/journal.pgen.1007948. eCollection 2019 Mar.

7.

Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.

Ling SC, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan SH, Tse TM, Chang JC, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, McAlonis-Downes M, Han JS, Swing D, Kapeli K, Yeo GW, Tessarollo L, Marsala M, Shaw CE, Tucker-Kellogg G, La Spada AR, Lagier-Tourenne C, Da Cruz S, Cleveland DW.

Elife. 2019 Feb 12;8. pii: e40811. doi: 10.7554/eLife.40811.

8.

Regulation of RNA editing by RNA-binding proteins in human cells.

Quinones-Valdez G, Tran SS, Jun HI, Bahn JH, Yang EW, Zhan L, Brümmer A, Wei X, Van Nostrand EL, Pratt GA, Yeo GW, Graveley BR, Xiao X.

Commun Biol. 2019 Jan 14;2:19. doi: 10.1038/s42003-018-0271-8. eCollection 2019.

9.

Widespread RNA editing dysregulation in brains from autistic individuals.

Tran SS, Jun HI, Bahn JH, Azghadi A, Ramaswami G, Van Nostrand EL, Nguyen TB, Hsiao YE, Lee C, Pratt GA, Martínez-Cerdeño V, Hagerman RJ, Yeo GW, Geschwind DH, Xiao X.

Nat Neurosci. 2019 Jan;22(1):25-36. doi: 10.1038/s41593-018-0287-x. Epub 2018 Dec 17.

10.

A Transcriptome-wide Translational Program Defined by LIN28B Expression Level.

Tan FE, Sathe S, Wheeler EC, Nussbacher JK, Peter S, Yeo GW.

Mol Cell. 2019 Jan 17;73(2):304-313.e3. doi: 10.1016/j.molcel.2018.10.041. Epub 2018 Dec 6.

PMID:
30527666
11.

RBP-Maps enables robust generation of splicing regulatory maps.

Yee BA, Pratt GA, Graveley BR, Van Nostrand EL, Yeo GW.

RNA. 2019 Feb;25(2):193-204. doi: 10.1261/rna.069237.118. Epub 2018 Nov 9.

12.

Patch-Seq Protocol to Analyze the Electrophysiology, Morphology and Transcriptome of Whole Single Neurons Derived From Human Pluripotent Stem Cells.

van den Hurk M, Erwin JA, Yeo GW, Gage FH, Bardy C.

Front Mol Neurosci. 2018 Aug 10;11:261. doi: 10.3389/fnmol.2018.00261. eCollection 2018.

13.

Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease.

Sommer A, Marxreiter F, Krach F, Fadler T, Grosch J, Maroni M, Graef D, Eberhardt E, Riemenschneider MJ, Yeo GW, Kohl Z, Xiang W, Gage FH, Winkler J, Prots I, Winner B.

Cell Stem Cell. 2018 Jul 5;23(1):123-131.e6. doi: 10.1016/j.stem.2018.06.015. Erratum in: Cell Stem Cell. 2019 Jun 6;24(6):1006.

PMID:
29979986
14.

An important class of intron retention events in human erythroblasts is regulated by cryptic exons proposed to function as splicing decoys.

Parra M, Booth BW, Weiszmann R, Yee B, Yeo GW, Brown JB, Celniker SE, Conboy JG.

RNA. 2018 Sep;24(9):1255-1265. doi: 10.1261/rna.066951.118. Epub 2018 Jun 29.

15.

Sequence, Structure, and Context Preferences of Human RNA Binding Proteins.

Dominguez D, Freese P, Alexis MS, Su A, Hochman M, Palden T, Bazile C, Lambert NJ, Van Nostrand EL, Pratt GA, Yeo GW, Graveley BR, Burge CB.

Mol Cell. 2018 Jun 7;70(5):854-867.e9. doi: 10.1016/j.molcel.2018.05.001. Epub 2018 Jun 7.

16.

Transcriptome-pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS.

Krach F, Batra R, Wheeler EC, Vu AQ, Wang R, Hutt K, Rabin SJ, Baughn MW, Libby RT, Diaz-Garcia S, Stauffer J, Pirie E, Saberi S, Rodriguez M, Madrigal AA, Kohl Z, Winner B, Yeo GW, Ravits J.

Acta Neuropathol. 2018 Sep;136(3):405-423. doi: 10.1007/s00401-018-1870-7. Epub 2018 Jun 7.

PMID:
29881994
17.

Tissue-selective restriction of RNA editing of CaV1.3 by splicing factor SRSF9.

Huang H, Kapeli K, Jin W, Wong YP, Arumugam TV, Koh JH, Srimasorn S, Mallilankaraman K, Chua JJE, Yeo GW, Soong TW.

Nucleic Acids Res. 2018 Aug 21;46(14):7323-7338. doi: 10.1093/nar/gky348.

18.

Systematic Discovery of RNA Binding Proteins that Regulate MicroRNA Levels.

Nussbacher JK, Yeo GW.

Mol Cell. 2018 Mar 15;69(6):1005-1016.e7. doi: 10.1016/j.molcel.2018.02.012.

19.

Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules.

Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW.

Cell. 2018 Jan 25;172(3):590-604.e13. doi: 10.1016/j.cell.2017.12.032.

20.

Self-Transfecting Micellar RNA: Modulating Nanoparticle Cell Interactions via High Density Display of Small Molecule Ligands on Micelle Coronas.

Roloff A, Nelles DA, Thompson MP, Yeo GW, Gianneschi NC.

Bioconjug Chem. 2018 Jan 17;29(1):126-135. doi: 10.1021/acs.bioconjchem.7b00657. Epub 2017 Dec 29.

21.

Erratum to: Robust, Cost-Effective Profiling of RNA Binding Protein Targets with Single-end Enhanced Crosslinking and Immunoprecipitation (seCLIP).

Van Nostrand EL, Nguyen TB, Gelboin-Burkhart C, Wang R, Blue SM, Pratt GA, Louie AL, Yeo GW.

Methods Mol Biol. 2017;1648:E1. doi: 10.1007/978-1-4939-7204-3_19. No abstract available.

PMID:
29230720
22.

Short poly(A) tails are a conserved feature of highly expressed genes.

Lima SA, Chipman LB, Nicholson AL, Chen YH, Yee BA, Yeo GW, Coller J, Pasquinelli AE.

Nat Struct Mol Biol. 2017 Dec;24(12):1057-1063. doi: 10.1038/nsmb.3499. Epub 2017 Nov 6.

23.

Nol12 is a multifunctional RNA binding protein at the nexus of RNA and DNA metabolism.

Scott DD, Trahan C, Zindy PJ, Aguilar LC, Delubac MY, Van Nostrand EL, Adivarahan S, Wei KE, Yeo GW, Zenklusen D, Oeffinger M.

Nucleic Acids Res. 2017 Dec 1;45(21):12509-12528. doi: 10.1093/nar/gkx963.

PMID:
29069457
24.

The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis.

Deffit SN, Yee BA, Manning AC, Rajendren S, Vadlamani P, Wheeler EC, Domissy A, Washburn MC, Yeo GW, Hundley HA.

Elife. 2017 Sep 19;6. pii: e28625. doi: 10.7554/eLife.28625.

25.

Advances and challenges in the detection of transcriptome-wide protein-RNA interactions.

Wheeler EC, Van Nostrand EL, Yeo GW.

Wiley Interdiscip Rev RNA. 2018 Jan;9(1). doi: 10.1002/wrna.1436. Epub 2017 Aug 29. Review.

26.

NEAT1 scaffolds RNA-binding proteins and the Microprocessor to globally enhance pri-miRNA processing.

Jiang L, Shao C, Wu QJ, Chen G, Zhou J, Yang B, Li H, Gou LT, Zhang Y, Wang Y, Yeo GW, Zhou Y, Fu XD.

Nat Struct Mol Biol. 2017 Oct;24(10):816-824. doi: 10.1038/nsmb.3455. Epub 2017 Aug 28.

27.

Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9.

Batra R, Nelles DA, Pirie E, Blue SM, Marina RJ, Wang H, Chaim IA, Thomas JD, Zhang N, Nguyen V, Aigner S, Markmiller S, Xia G, Corbett KD, Swanson MS, Yeo GW.

Cell. 2017 Aug 24;170(5):899-912.e10. doi: 10.1016/j.cell.2017.07.010. Epub 2017 Aug 10.

28.

Variation in single-nucleotide sensitivity of eCLIP derived from reverse transcription conditions.

Van Nostrand EL, Shishkin AA, Pratt GA, Nguyen TB, Yeo GW.

Methods. 2017 Aug 15;126:29-37. doi: 10.1016/j.ymeth.2017.08.002. Epub 2017 Aug 5.

29.

Robust, Cost-Effective Profiling of RNA Binding Protein Targets with Single-end Enhanced Crosslinking and Immunoprecipitation (seCLIP).

Van Nostrand EL, Nguyen TB, Gelboin-Burkhart C, Wang R, Blue SM, Pratt GA, Louie AL, Yeo GW.

Methods Mol Biol. 2017;1648:177-200. doi: 10.1007/978-1-4939-7204-3_14. Erratum in: Methods Mol Biol. 2017;1648:E1.

30.

Genetic mutations in RNA-binding proteins and their roles in ALS.

Kapeli K, Martinez FJ, Yeo GW.

Hum Genet. 2017 Sep;136(9):1193-1214. doi: 10.1007/s00439-017-1830-7. Epub 2017 Jul 31. Review.

31.

Single-Cell Alternative Splicing Analysis with Expedition Reveals Splicing Dynamics during Neuron Differentiation.

Song Y, Botvinnik OB, Lovci MT, Kakaradov B, Liu P, Xu JL, Yeo GW.

Mol Cell. 2017 Jul 6;67(1):148-161.e5. doi: 10.1016/j.molcel.2017.06.003. Epub 2017 Jun 29.

32.

Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation.

Zeng C, Mulas F, Sui Y, Guan T, Miller N, Tan Y, Liu F, Jin W, Carrano AC, Huising MO, Shirihai OS, Yeo GW, Sander M.

Cell Metab. 2017 May 2;25(5):1160-1175.e11. doi: 10.1016/j.cmet.2017.04.014.

33.

High-Throughput and Cost-Effective Characterization of Induced Pluripotent Stem Cells.

D'Antonio M, Woodruff G, Nathanson JL, D'Antonio-Chronowska A, Arias A, Matsui H, Williams R, Herrera C, Reyna SM, Yeo GW, Goldstein LSB, Panopoulos AD, Frazer KA.

Stem Cell Reports. 2017 Apr 11;8(4):1101-1111. doi: 10.1016/j.stemcr.2017.03.011.

34.

iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types.

Panopoulos AD, D'Antonio M, Benaglio P, Williams R, Hashem SI, Schuldt BM, DeBoever C, Arias AD, Garcia M, Nelson BC, Harismendy O, Jakubosky DA, Donovan MKR, Greenwald WW, Farnam K, Cook M, Borja V, Miller CA, Grinstein JD, Drees F, Okubo J, Diffenderfer KE, Hishida Y, Modesto V, Dargitz CT, Feiring R, Zhao C, Aguirre A, McGarry TJ, Matsui H, Li H, Reyna J, Rao F, O'Connor DT, Yeo GW, Evans SM, Chi NC, Jepsen K, Nariai N, Müller FJ, Goldstein LSB, Izpisua Belmonte JC, Adler E, Loring JF, Berggren WT, D'Antonio-Chronowska A, Smith EN, Frazer KA.

Stem Cell Reports. 2017 Apr 11;8(4):1086-1100. doi: 10.1016/j.stemcr.2017.03.012.

35.

Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing.

Kakaradov B, Arsenio J, Widjaja CE, He Z, Aigner S, Metz PJ, Yu B, Wehrens EJ, Lopez J, Kim SH, Zuniga EI, Goldrath AW, Chang JT, Yeo GW.

Nat Immunol. 2017 Apr;18(4):422-432. doi: 10.1038/ni.3688. Epub 2017 Feb 20.

36.

Interaction Landscape of Inherited Polymorphisms with Somatic Events in Cancer.

Carter H, Marty R, Hofree M, Gross AM, Jensen J, Fisch KM, Wu X, DeBoever C, Van Nostrand EL, Song Y, Wheeler E, Kreisberg JF, Lippman SM, Yeo GW, Gutkind JS, Ideker T.

Cancer Discov. 2017 Apr;7(4):410-423. doi: 10.1158/2159-8290.CD-16-1045. Epub 2017 Feb 10.

37.

Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing.

Lardelli RM, Schaffer AE, Eggens VR, Zaki MS, Grainger S, Sathe S, Van Nostrand EL, Schlachetzki Z, Rosti B, Akizu N, Scott E, Silhavy JL, Heckman LD, Rosti RO, Dikoglu E, Gregor A, Guemez-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, Markmiller S, Marin-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, Blaser S, Çağlayan AO, Bilguvar K, Per H, Fagerberg C, Christesen HT, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi NC, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Nassogne MC, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J, Gleeson JG.

Nat Genet. 2017 Mar;49(3):457-464. doi: 10.1038/ng.3762. Epub 2017 Jan 16.

38.

CRISPR/Cas9-mediated integration enables TAG-eCLIP of endogenously tagged RNA binding proteins.

Van Nostrand EL, Gelboin-Burkhart C, Wang R, Pratt GA, Blue SM, Yeo GW.

Methods. 2017 Apr 15;118-119:50-59. doi: 10.1016/j.ymeth.2016.12.007. Epub 2016 Dec 18.

39.

MicroRNA-101 Regulates Multiple Developmental Programs to Constrain Excitation in Adult Neural Networks.

Lippi G, Fernandes CC, Ewell LA, John D, Romoli B, Curia G, Taylor SR, Frady EP, Jensen AB, Liu JC, Chaabane MM, Belal C, Nathanson JL, Zoli M, Leutgeb JK, Biagini G, Yeo GW, Berg DK.

Neuron. 2016 Dec 21;92(6):1337-1351. doi: 10.1016/j.neuron.2016.11.017. Epub 2016 Dec 8.

40.

Making the cut in the dark genome.

Einstein JM, Yeo GW.

Science. 2016 Nov 11;354(6313):705-706. No abstract available.

PMID:
27846591
41.

From Protein-RNA Predictions toward a Peptide-RNA Code.

Brannan KW, Yeo GW.

Mol Cell. 2016 Nov 3;64(3):437-438. doi: 10.1016/j.molcel.2016.10.023.

42.

RNA-binding protein CPEB1 remodels host and viral RNA landscapes.

Batra R, Stark TJ, Clark E, Belzile JP, Wheeler EC, Yee BA, Huang H, Gelboin-Burkhart C, Huelga SC, Aigner S, Roberts BT, Bos TJ, Sathe S, Donohue JP, Rigo F, Ares M Jr, Spector DH, Yeo GW.

Nat Struct Mol Biol. 2016 Dec;23(12):1101-1110. doi: 10.1038/nsmb.3310. Epub 2016 Oct 24.

43.

Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System.

Martinez FJ, Pratt GA, Van Nostrand EL, Batra R, Huelga SC, Kapeli K, Freese P, Chun SJ, Ling K, Gelboin-Burkhart C, Fijany L, Wang HC, Nussbacher JK, Broski SM, Kim HJ, Lardelli R, Sundararaman B, Donohue JP, Javaherian A, Lykke-Andersen J, Finkbeiner S, Bennett CF, Ares M Jr, Burge CB, Taylor JP, Rigo F, Yeo GW.

Neuron. 2016 Nov 23;92(4):780-795. doi: 10.1016/j.neuron.2016.09.050. Epub 2016 Oct 20.

44.

Pairing beyond the Seed Supports MicroRNA Targeting Specificity.

Broughton JP, Lovci MT, Huang JL, Yeo GW, Pasquinelli AE.

Mol Cell. 2016 Oct 20;64(2):320-333. doi: 10.1016/j.molcel.2016.09.004. Epub 2016 Oct 6.

45.

SONAR Discovers RNA-Binding Proteins from Analysis of Large-Scale Protein-Protein Interactomes.

Brannan KW, Jin W, Huelga SC, Banks CA, Gilmore JM, Florens L, Washburn MP, Van Nostrand EL, Pratt GA, Schwinn MK, Daniels DL, Yeo GW.

Mol Cell. 2016 Oct 20;64(2):282-293. doi: 10.1016/j.molcel.2016.09.003. Epub 2016 Oct 6.

46.

Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology.

Bardy C, van den Hurk M, Kakaradov B, Erwin JA, Jaeger BN, Hernandez RV, Eames T, Paucar AA, Gorris M, Marchand C, Jappelli R, Barron J, Bryant AK, Kellogg M, Lasken RS, Rutten BP, Steinbusch HW, Yeo GW, Gage FH.

Mol Psychiatry. 2016 Nov;21(11):1573-1588. doi: 10.1038/mp.2016.158. Epub 2016 Oct 4.

47.

The Calcineurin Variant CnAβ1 Controls Mouse Embryonic Stem Cell Differentiation by Directing mTORC2 Membrane Localization and Activation.

Gómez-Salinero JM, López-Olañeta MM, Ortiz-Sánchez P, Larrasa-Alonso J, Gatto A, Felkin LE, Barton PJR, Navarro-Lérida I, Ángel Del Pozo M, García-Pavía P, Sundararaman B, Giovinazo G, Yeo GW, Lara-Pezzi E.

Cell Chem Biol. 2016 Nov 17;23(11):1372-1382. doi: 10.1016/j.chembiol.2016.09.010. Epub 2016 Oct 13.

48.

Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model.

Grabole N, Zhang JD, Aigner S, Ruderisch N, Costa V, Weber FC, Theron M, Berntenis N, Spleiss O, Ebeling M, Yeo GW, Jagasia R, Kiialainen A.

Genome Med. 2016 Sep 21;8(1):94.

49.

Systematic review of dementia prevalence and incidence in United States race/ethnic populations.

Mehta KM, Yeo GW.

Alzheimers Dement. 2017 Jan;13(1):72-83. doi: 10.1016/j.jalz.2016.06.2360. Epub 2016 Sep 4. Review.

PMID:
27599209
50.

Rbfox2 function in RNA metabolism is impaired in hypoplastic left heart syndrome patient hearts.

Verma SK, Deshmukh V, Nutter CA, Jaworski E, Jin W, Wadhwa L, Abata J, Ricci M, Lincoln J, Martin JF, Yeo GW, Kuyumcu-Martinez MN.

Sci Rep. 2016 Aug 3;6:30896. doi: 10.1038/srep30896.

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