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Items: 1 to 50 of 151


The role of NOX inhibitors in neurodegenerative diseases.

Barua S, Kim JY, Yenari MA, Lee JE.

IBRO Rep. 2019 Aug 1;7:59-69. doi: 10.1016/j.ibror.2019.07.1721. eCollection 2019 Dec. Review.


Plasma Lipoprotein-associated Phospholipase A2 and Superoxide Dismutase are Independent Predicators of Cognitive Impairment in Cerebral Small Vessel Disease Patients: Diagnosis and Assessment.

Zhu S, Wei X, Yang X, Huang Z, Chang Z, Xie F, Yang Q, Ding C, Xiang W, Yang H, Xia Y, Feng ZP, Sun HS, Yenari MA, Shi L, Mok VC, Wang Q.

Aging Dis. 2019 Aug 1;10(4):834-846. doi: 10.14336/AD.2019.0304. eCollection 2019 Aug.


Therapeutic Hypothermia and Neuroprotection in Acute Neurological Disease.

Kurisu K, Kim JY, You J, Yenari MA.

Curr Med Chem. 2019 May 6. doi: 10.2174/0929867326666190506124836. [Epub ahead of print]


Triggering receptor expressed on myeloid cells-2 expression in the brain is required for maximal phagocytic activity and improved neurological outcomes following experimental stroke.

Kurisu K, Zheng Z, Kim JY, Shi J, Kanoke A, Liu J, Hsieh CL, Yenari MA.

J Cereb Blood Flow Metab. 2019 Oct;39(10):1906-1918. doi: 10.1177/0271678X18817282. Epub 2018 Dec 7.


Microglial Calcium Release-Activated Calcium Channel Inhibition Improves Outcome from Experimental Traumatic Brain Injury and Microglia-Induced Neuronal Death.

Mizuma A, Kim JY, Kacimi R, Stauderman K, Dunn M, Hebbar S, Yenari MA.

J Neurotrauma. 2019 Apr 1;36(7):996-1007. doi: 10.1089/neu.2018.5856. Epub 2018 Dec 4.


Targeting Reperfusion Injury in the Age of Mechanical Thrombectomy.

Mizuma A, You JS, Yenari MA.

Stroke. 2018 Jul;49(7):1796-1802. doi: 10.1161/STROKEAHA.117.017286. Epub 2018 May 14. Review. No abstract available.


Advances in Stroke 2017.

Bernhardt J, Zorowitz RD, Becker KJ, Keller E, Saposnik G, Strbian D, Dichgans M, Woo D, Reeves M, Thrift A, Kidwell CS, Olivot JM, Goyal M, Pierot L, Bennett DA, Howard G, Ford GA, Goldstein LB, Planas AM, Yenari MA, Greenberg SM, Pantoni L, Amin-Hanjani S, Tymianski M.

Stroke. 2018 May;49(5):e174-e199. doi: 10.1161/STROKEAHA.118.021380. Epub 2018 Apr 18. Review. No abstract available.


The 70-kDa heat shock protein (Hsp70) as a therapeutic target for stroke.

Kim JY, Han Y, Lee JE, Yenari MA.

Expert Opin Ther Targets. 2018 Mar;22(3):191-199. doi: 10.1080/14728222.2018.1439477. Epub 2018 Feb 15. Review.


Reconsidering Neuroprotection in the Reperfusion Era.

Savitz SI, Baron JC, Yenari MA, Sanossian N, Fisher M.

Stroke. 2017 Dec;48(12):3413-3419. doi: 10.1161/STROKEAHA.117.017283. Epub 2017 Nov 16. Review. No abstract available.


Anti-Inflammatory Targets for the Treatment of Reperfusion Injury in Stroke.

Mizuma A, Yenari MA.

Front Neurol. 2017 Sep 7;8:467. doi: 10.3389/fneur.2017.00467. eCollection 2017. Review.


NOX Inhibitors - A Promising Avenue for Ischemic Stroke.

Kim JY, Park J, Lee JE, Yenari MA.

Exp Neurobiol. 2017 Aug;26(4):195-205. doi: 10.5607/en.2017.26.4.195. Epub 2017 Aug 25. Review.


Therapeutic hypothermia for ischemic stroke; pathophysiology and future promise.

Kurisu K, Yenari MA.

Neuropharmacology. 2018 May 15;134(Pt B):302-309. doi: 10.1016/j.neuropharm.2017.08.025. Epub 2017 Aug 19. Review.


Hypothermia Identifies Dynamin as a Potential Therapeutic Target in Experimental Stroke.

Kim JY, Kim N, Lee JE, Yenari MA.

Ther Hypothermia Temp Manag. 2017 Sep;7(3):171-177. doi: 10.1089/ther.2017.0005. Epub 2017 Jun 30.


Activated complement protein C5a does not affect brain-derived endothelial cell viability and zonula occludens-1 levels following oxygen-glucose deprivation.

Khoyetsyan A, Kacimi R, Tsakanova G, Boyajyan A, Arakelyan A, Yenari MA.

Brain Circ. 2017 Jan-Mar;3(1):14-20. doi: 10.4103/2394-8108.203258. Epub 2017 Mar 29.


70-kDa Heat Shock Protein Downregulates Dynamin in Experimental Stroke: A New Therapeutic Target?

Kim JY, Kim N, Zheng Z, Lee JE, Yenari MA.

Stroke. 2016 Aug;47(8):2103-11. doi: 10.1161/STROKEAHA.116.012763. Epub 2016 Jul 7.


Postinjury Neuroplasticity in Central Neural Networks.

Lee BH, Lim TH, Yoon YW, Yenari MA, Jeong Y.

Neural Plast. 2015;2015:857085. doi: 10.1155/2015/857085. Epub 2015 Oct 18. No abstract available.


Pharmacologic heat shock protein 70 induction confers cytoprotection against inflammation in gliovascular cells.

Kacimi R, Yenari MA.

Glia. 2015 Jul;63(7):1200-12. doi: 10.1002/glia.22811. Epub 2015 Mar 20.


Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke.

Kawabori M, Kacimi R, Kauppinen T, Calosing C, Kim JY, Hsieh CL, Nakamura MC, Yenari MA.

J Neurosci. 2015 Feb 25;35(8):3384-96. doi: 10.1523/JNEUROSCI.2620-14.2015.


Inflammatory responses in brain ischemia.

Kawabori M, Yenari MA.

Curr Med Chem. 2015;22(10):1258-77. Review.


Calcium-sensing receptor (CaSR) as a novel target for ischemic neuroprotection.

Kim JY, Ho H, Kim N, Liu J, Tu CL, Yenari MA, Chang W.

Ann Clin Transl Neurol. 2014 Nov;1(11):851-66. doi: 10.1002/acn3.118. Epub 2014 Oct 3.


Regulation of inflammatory transcription factors by heat shock protein 70 in primary cultured astrocytes exposed to oxygen-glucose deprivation.

Kim JY, Yenari MA, Lee JE.

Neuroscience. 2015 Feb 12;286:272-80. doi: 10.1016/j.neuroscience.2014.11.057. Epub 2014 Dec 5.


Mechanisms and potential therapeutic applications of microglial activation after brain injury.

Kim JY, Kim N, Yenari MA.

CNS Neurosci Ther. 2015 Apr;21(4):309-19. doi: 10.1111/cns.12360. Epub 2014 Dec 4. Review.


Pharmacological induction of the 70-kDa heat shock protein protects against brain injury.

Kim N, Kim JY, Yenari MA.

Neuroscience. 2015 Jan 22;284:912-9. doi: 10.1016/j.neuroscience.2014.11.010. Epub 2014 Nov 13.


The role of the microglia in acute CNS injury.

Kawabori M, Yenari MA.

Metab Brain Dis. 2015 Apr;30(2):381-92. doi: 10.1007/s11011-014-9531-6. Epub 2014 Mar 29. Review.


Triggering Receptor Expressed on Myeloid Cells-2 Correlates to Hypothermic Neuroprotection in Ischemic Stroke.

Kawabori M, Hokari M, Zheng Z, Kim JY, Calosing C, Hsieh CL, Nakamura MC, Yenari MA.

Ther Hypothermia Temp Manag. 2013 Dec 1;3(4):189-198.


Innate inflammatory responses in stroke: mechanisms and potential therapeutic targets.

Kim JY, Kawabori M, Yenari MA.

Curr Med Chem. 2014;21(18):2076-97. Review.


Microglial P2Y12 deficiency/inhibition protects against brain ischemia.

Webster CM, Hokari M, McManus A, Tang XN, Ma H, Kacimi R, Yenari MA.

PLoS One. 2013 Aug 5;8(8):e70927. doi: 10.1371/journal.pone.0070927. Print 2013.


Influence of therapeutic hypothermia on regeneration after cerebral ischemia.

Yenari MA, Han HS.

Front Neurol Neurosci. 2013;32:122-8. doi: 10.1159/000346428. Epub 2013 Jul 8. Review.


The 70 kDa heat shock protein protects against experimental traumatic brain injury.

Kim JY, Kim N, Zheng Z, Lee JE, Yenari MA.

Neurobiol Dis. 2013 Oct;58:289-95. doi: 10.1016/j.nbd.2013.06.012. Epub 2013 Jun 29.


Sphingolipids in cardiovascular and cerebrovascular systems: Pathological implications and potential therapeutic targets.

Kawabori M, Kacimi R, Karliner JS, Yenari MA.

World J Cardiol. 2013 Apr 26;5(4):75-86. doi: 10.4330/wjc.v5.i4.75.


The immune modulating properties of the heat shock proteins after brain injury.

Kim JY, Yenari MA.

Anat Cell Biol. 2013 Mar;46(1):1-7. doi: 10.5115/acb.2013.46.1.1. Epub 2013 Mar 25.


Neuroprotection after cerebral ischemia.

Namura S, Ooboshi H, Liu J, Yenari MA.

Ann N Y Acad Sci. 2013 Mar;1278:25-32. doi: 10.1111/nyas.12087.


The multifaceted effects of agmatine on functional recovery after spinal cord injury through Modulations of BMP-2/4/7 expressions in neurons and glial cells.

Park YM, Lee WT, Bokara KK, Seo SK, Park SH, Kim JH, Yenari MA, Park KA, Lee JE.

PLoS One. 2013;8(1):e53911. doi: 10.1371/journal.pone.0053911. Epub 2013 Jan 21.


Bone marrow chimeras in the study of experimental stroke.

Tang XN, Zheng Z, Yenari MA.

Transl Stroke Res. 2012 Sep;3(3):341-7. doi: 10.1007/s12975-012-0169-6. Epub 2012 May 5.


NADPH oxidase in stroke and cerebrovascular disease.

Tang XN, Cairns B, Kim JY, Yenari MA.

Neurol Res. 2012 May;34(4):338-45. doi: 10.1179/1743132812Y.0000000021. Review.


Neuroprotective mechanisms of hypothermia in brain ischaemia.

Yenari MA, Han HS.

Nat Rev Neurosci. 2012 Feb 22;13(4):267-78. doi: 10.1038/nrn3174. Review.


Therapeutic hypothermia in stroke.

Yenari MA, Colbourne F, Hemmen TM, Han HS, Krieger D.

Stroke Res Treat. 2011;2011:157969. doi: 10.4061/2011/157969. Epub 2012 Jan 24. No abstract available.


Anti-inflammatory properties and pharmacological induction of Hsp70 after brain injury.

Kim N, Kim JY, Yenari MA.

Inflammopharmacology. 2012 Jun;20(3):177-85. doi: 10.1007/s10787-011-0115-3. Epub 2012 Jan 13. Review.


NOX inhibitors as a therapeutic strategy for stroke and neurodegenerative disease.

Cairns B, Kim JY, Tang XN, Yenari MA.

Curr Drug Targets. 2012 Feb;13(2):199-206. Review.


Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke.

Tang XN, Zheng Z, Giffard RG, Yenari MA.

Ann Neurol. 2011 Oct;70(4):606-15. doi: 10.1002/ana.22476.


Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by Increasing superoxide production.

Won SJ, Tang XN, Suh SW, Yenari MA, Swanson RA.

Ann Neurol. 2011 Oct;70(4):583-90. doi: 10.1002/ana.22538. Epub 2011 Oct 14.


Brain 11: what's new in stroke research?

Yenari MA, Lee JE.

Expert Rev Neurother. 2011 Sep;11(9):1235-7. doi: 10.1586/ern.11.107.


Therapeutic hypothermia after cardiac arrest: experience at an academically affiliated community-based veterans affairs medical center.

Shah MP, Zimmerman L, Bullard J, Yenari MA.

Stroke Res Treat. 2011;2011:791639. doi: 10.4061/2011/791639. Epub 2011 Jul 12.


Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses.

Yan J, Xu Y, Zhu C, Zhang L, Wu A, Yang Y, Xiong Z, Deng C, Huang XF, Yenari MA, Yang YG, Ying W, Wang Q.

PLoS One. 2011;6(6):e20945. doi: 10.1371/journal.pone.0020945. Epub 2011 Jun 22.


Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways.

Kacimi R, Giffard RG, Yenari MA.

J Inflamm (Lond). 2011 Mar 7;8:7. doi: 10.1186/1476-9255-8-7.


Direct protection of cultured neurons from ischemia-like injury by minocycline.

Huang WC, Qiao Y, Xu L, Kacimi R, Sun X, Giffard RG, Yenari MA.

Anat Cell Biol. 2010 Dec;43(4):325-31. doi: 10.5115/acb.2010.43.4.325. Epub 2010 Dec 31.

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