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The Redox Role of G6PD in Cell Growth, Cell Death, and Cancer.

Yang HC, Wu YH, Yen WC, Liu HY, Hwang TL, Stern A, Chiu DT.

Cells. 2019 Sep 8;8(9). pii: E1055. doi: 10.3390/cells8091055. Review.


Proteomic Profiling of Paired Interstitial Fluids Reveals Dysregulated Pathways and Salivary NID1 as a Biomarker of Oral Cavity Squamous Cell Carcinoma.

Hsu CW, Chang KP, Huang Y, Liu HP, Hsueh PC, Gu PW, Yen WC, Wu CC.

Mol Cell Proteomics. 2019 Oct;18(10):1939-1949. doi: 10.1074/mcp.RA119.001654. Epub 2019 Jul 17.


Primary care performance of alternatively licenced physicians in Ontario, Canada: a cross-sectional study using administrative data.

Hodwitz K, Thakkar N, Schultz SE, Jaakkimainen L, Faulkner D, Yen W.

BMJ Open. 2019 Jun 11;9(6):e026296. doi: 10.1136/bmjopen-2018-026296.


Distinct Requirements of CHD4 during B Cell Development and Antibody Response.

Yen WF, Sharma R, Cols M, Lau CM, Chaudhry A, Chowdhury P, Yewdell WT, Vaidyanathan B, Sun A, Coffre M, Pucella JN, Chen CC, Jasin M, Sun JC, Rudensky AY, Koralov SB, Chaudhuri J.

Cell Rep. 2019 Apr 30;27(5):1472-1486.e5. doi: 10.1016/j.celrep.2019.04.011.


Cutting Edge: ATM Influences Germinal Center Integrity.

Nicolas L, Cols M, Smolkin R, Fernandez KC, Yewdell WT, Yen WF, Zha S, Vuong BQ, Chaudhuri J.

J Immunol. 2019 Jun 1;202(11):3137-3142. doi: 10.4049/jimmunol.1801033. Epub 2019 Apr 26.


A new oligonucleotide array for the detection of multidrug and extensively drug-resistance tuberculosis.

Chen CY, Weng JY, Huang HH, Yen WC, Tsai YH, Cheng TC, Jou R.

Sci Rep. 2019 Mar 14;9(1):4425. doi: 10.1038/s41598-019-39339-3.


Experiential knowledge of risk and support factors for physician performance in Canada: a qualitative study.

Kain NA, Hodwitz K, Yen W, Ashworth N.

BMJ Open. 2019 Feb 22;9(2):e023511. doi: 10.1136/bmjopen-2018-023511.


The B Cell Activation-Induced miR-183 Cluster Plays a Minimal Role in Canonical Primary Humoral Responses.

Pucella JN, Cols M, Yen WF, Xu S, Chaudhuri J.

J Immunol. 2019 Mar 1;202(5):1383-1396. doi: 10.4049/jimmunol.1800071. Epub 2019 Jan 25.


Modeling the antecedents of clinical examination performance: Task characteristics and psychological state in nursing students.

Pai HC, Wei CF, Chen SL, Tsai SM, Yen WJ.

Nurse Educ Today. 2018 Oct;69:142-148. doi: 10.1016/j.nedt.2018.07.016. Epub 2018 Aug 1.


Weight and height faltering in the indigenous children (Orang Asli) of Peninsular Malaysia during the first 2 years of life.

Yen WC, Shariff ZM, Adznam SN, Sulaiman N, Siew CY.

Asia Pac J Clin Nutr. 2018;27(4):886-892. doi: 10.6133/apjcn.072017.02.


A Call to Investigate the Relationship Between Education and Health Outcomes Using Big Data.

Chahine S, Kulasegaram KM, Wright S, Monteiro S, Grierson LEM, Barber C, Sebok-Syer SS, McConnell M, Yen W, De Champlain A, Touchie C.

Acad Med. 2018 Jun;93(6):829-832. doi: 10.1097/ACM.0000000000002217.


In silico and crystallographic studies identify key structural features of biliverdin IXβ reductase inhibitors having nanomolar potency.

Nesbitt NM, Zheng X, Li Z, Manso JA, Yen WY, Malone LE, Ripoll-Rozada J, Pereira PJB, Mantle TJ, Wang J, Bahou WF.

J Biol Chem. 2018 Apr 13;293(15):5431-5446. doi: 10.1074/jbc.RA118.001803. Epub 2018 Feb 27.


Development of the Chinese-version of the exercise self-regulatory efficacy scale for patients with chronic obstructive pulmonary disease.

Tsai YH, Chen JL, Davis AHT, Yen WJ, Lin YJ, Chiang LC, Chen YJ.

Heart Lung. 2018 Jan - Feb;47(1):16-23. doi: 10.1016/j.hrtlng.2017.10.007. Epub 2017 Nov 11.


RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations.

Fischer MM, Yeung VP, Cattaruzza F, Hussein R, Yen WC, Murriel C, Evans JW, O'Young G, Brunner AL, Wang M, Cain J, Cancilla B, Kapoun A, Hoey T.

Sci Rep. 2017 Nov 10;7(1):15270. doi: 10.1038/s41598-017-15704-y.


A Study on Scalp Hair Health and Hair Care Practices among Malaysian Medical Students.

Nayak BS, Ann CY, Azhar AB, Ling ECS, Yen WH, Aithal PA.

Int J Trichology. 2017 Apr-Jun;9(2):58-62. doi: 10.4103/ijt.ijt_76_16.


Digital quantification of DNA via isothermal amplification on a self-driven microfluidic chip featuring hydrophilic film-coated polydimethylsiloxane.

Ma YD, Chang WH, Luo K, Wang CH, Liu SY, Yen WH, Lee GB.

Biosens Bioelectron. 2018 Jan 15;99:547-554. doi: 10.1016/j.bios.2017.08.026. Epub 2017 Aug 12.


The mediating effect of self-reflection and learning effectiveness on clinical nursing performance in nursing students: A follow-up study.

Pai HC, Ko HL, Eng CJ, Yen WJ.

J Prof Nurs. 2017 Jul - Aug;33(4):287-292. doi: 10.1016/j.profnurs.2017.01.003. Epub 2017 Jan 24.


BRCT-domain protein BRIT1 influences class switch recombination.

Yen WF, Chaudhry A, Vaidyanathan B, Yewdell WT, Pucella JN, Sharma R, Liang Y, Li K, Rudensky AY, Chaudhuri J.

Proc Natl Acad Sci U S A. 2017 Jul 19. pii: 201708211. doi: 10.1073/pnas.1708211114. [Epub ahead of print]


WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death.

Fischer MM, Cancilla B, Yeung VP, Cattaruzza F, Chartier C, Murriel CL, Cain J, Tam R, Cheng CY, Evans JW, O'Young G, Song X, Lewicki J, Kapoun AM, Gurney A, Yen WC, Hoey T.

Sci Adv. 2017 Jun 21;3(6):e1700090. doi: 10.1126/sciadv.1700090. eCollection 2017 Jun.


ATM loss leads to synthetic lethality in BRCA1 BRCT mutant mice associated with exacerbated defects in homology-directed repair.

Chen CC, Kass EM, Yen WF, Ludwig T, Moynahan ME, Chaudhuri J, Jasin M.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7665-7670. doi: 10.1073/pnas.1706392114. Epub 2017 Jun 28.


One-Flask Synthesis of Pyrazolo[3,4-d]pyrimidines from 5-Aminopyrazoles and Mechanistic Study.

Yen WP, Tsai SE, Uramaru N, Takayama H, Wong FF.

Molecules. 2017 May 16;22(5). pii: E820. doi: 10.3390/molecules22050820.


The influence of globalization on medical regulation: a descriptive analysis of international medical graduates registered through alternative licensure routes in Ontario.

Yen W, Hodwitz K, Thakkar N, Martimianakis MA, Faulkner D.

Can Med Educ J. 2016 Dec 5;7(3):e19-e30. eCollection 2016 Dec.


Correction to A Mesoporous Silica Biomaterial for Dental Biomimetic Crystallization.

Chiang YC, Lin HP, Chang HH, Cheng YW, Tang HY, Yen WC, Lin PY, Chang KW, Lin CP.

ACS Nano. 2017 Feb 28;11(2):2305. doi: 10.1021/acsnano.7b00761. Epub 2017 Feb 15. No abstract available.


Cutting Edge: The Transcription Factor Sox2 Regulates AID Expression in Class-Switched B Cells.

DiMenna LJ, Yen WF, Nicolas L, Sharma R, Saldanha ZN, Chaudhuri J.

J Immunol. 2017 Mar 15;198(6):2244-2248. doi: 10.4049/jimmunol.1502266. Epub 2017 Feb 10.


The aryl hydrocarbon receptor controls cell-fate decisions in B cells.

Vaidyanathan B, Chaudhry A, Yewdell WT, Angeletti D, Yen WF, Wheatley AK, Bradfield CA, McDermott AB, Yewdell JW, Rudensky AY, Chaudhuri J.

J Exp Med. 2017 Jan;214(1):197-208. doi: 10.1084/jem.20160789. Epub 2016 Dec 23.


Dysregulation of PINCH signaling in mesial temporal epilepsy.

Liu C, Russin J, Heck C, Kawata K, Adiga R, Yen W, Lambert J, Stear B, Law M, Marquez Y, Crino P, Millett D, Langford D.

J Clin Neurosci. 2017 Feb;36:43-52. doi: 10.1016/j.jocn.2016.10.012. Epub 2016 Nov 9.


Collaborating with mammographers to address their work-related musculoskeletal discomfort.

Sommerich CM, Lavender SA, Evans KD, Sanders E, Joines S, Lamar S, Radin Umar RZ, Yen WT, Park S.

Ergonomics. 2016 Oct;59(10):1307-1317. Epub 2016 Apr 6.


InGaAs Nanomembrane/Si van der Waals Heterojunction Photodiodes with Broadband and High Photoresponsivity.

Um DS, Lee Y, Lim S, Park J, Yen WC, Chueh YL, Kim HJ, Ko H.

ACS Appl Mater Interfaces. 2016 Oct 5;8(39):26105-26111. Epub 2016 Sep 23.


Diminished COX-2/PGE2-Mediated Antiviral Response Due to Impaired NOX/MAPK Signaling in G6PD-Knockdown Lung Epithelial Cells.

Lin HR, Wu YH, Yen WC, Yang CM, Chiu DT.

PLoS One. 2016 Apr 20;11(4):e0153462. doi: 10.1371/journal.pone.0153462. eCollection 2016.


Sp1-mediated ectopic expression of T-cell lymphoma invasion and metastasis 2 in hepatocellular carcinoma.

Yen WH, Ke WS, Hung JJ, Chen TM, Chen JS, Sun HS.

Cancer Med. 2016 Mar;5(3):465-77. doi: 10.1002/cam4.611. Epub 2016 Jan 14.


Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates β-Catenin Signaling and Tumorigenesis in Multiple Cancer Types.

Chartier C, Raval J, Axelrod F, Bond C, Cain J, Dee-Hoskins C, Ma S, Fischer MM, Shah J, Wei J, Ji M, Lam A, Stroud M, Yen WC, Yeung P, Cancilla B, O'Young G, Wang M, Kapoun AM, Lewicki J, Hoey T, Gurney A.

Cancer Res. 2016 Feb 1;76(3):713-23. doi: 10.1158/0008-5472.CAN-15-0561. Epub 2015 Dec 30.


Emphysematous cholecystitis.

Yen WL, Hsu CF, Tsai MJ.

Ci Ji Yi Xue Za Zhi. 2016 Jan-Mar;28(1):37-38. doi: 10.1016/j.tcmj.2015.12.001. Epub 2016 Jan 16. No abstract available.


Exocytosis of Endothelial Lysosome-Related Organelles Hair-Triggers a Patchy Loss of Glycocalyx at the Onset of Sepsis.

Zullo JA, Fan J, Azar TT, Yen W, Zeng M, Chen J, Ratliff BB, Song J, Tarbell JM, Goligorsky MS, Fu BM.

Am J Pathol. 2016 Feb;186(2):248-58. doi: 10.1016/j.ajpath.2015.10.001. Epub 2015 Dec 10.


Collaborating with cardiac sonographers to develop work-related musculoskeletal disorder interventions.

Sommerich CM, Lavender SA, Evans K, Sanders E, Joines S, Lamar S, Radin Umar RZ, Yen WT, Li J, Nagavarapu S, Dickerson JA.

Ergonomics. 2016 Sep;59(9):1193-204. doi: 10.1080/00140139.2015.1116613. Epub 2016 Feb 3.


Bacillus formosensis sp. nov., isolated from pesticide wastewater.

Lin SY, Hameed A, Liu YC, Hsu YH, Lai WA, Yen WS, Young CC.

Int J Syst Evol Microbiol. 2015 Nov;65(11):3800-3805. doi: 10.1099/ijsem.0.000497.


Evaluation of jar lid design characteristics by older women with hand use limitations.

Yen WT, Sommerich CM, Lavender SA, Flinn SR, Sanders EB.

Appl Ergon. 2016 Jan;52:177-84. doi: 10.1016/j.apergo.2015.07.011. Epub 2015 Aug 3.


Correction: miR-182 Is Largely Dispensable for Adaptive Immunity: Lack of Correlation between Expression and Function.

Pucella JN, Yen WF, Kim MV, van der Veeken J, Socci ND, Naito Y, Li MO, Iwai N, Chaudhuri J.

J Immunol. 2015 Aug 15;195(4):1903. doi: 10.4049/jimmunol.1501331. No abstract available.


Facilitated Reflective Performance Feedback: Developing an Evidence- and Theory-Based Model That Builds Relationship, Explores Reactions and Content, and Coaches for Performance Change (R2C2).

Sargeant J, Lockyer J, Mann K, Holmboe E, Silver I, Armson H, Driessen E, MacLeod T, Yen W, Ross K, Power M.

Acad Med. 2015 Dec;90(12):1698-706. doi: 10.1097/ACM.0000000000000809.


Development of Cryopreservation Techniques for Gorgonian (Junceella juncea) Oocytes through Vitrification.

Tsai S, Yen W, Chavanich S, Viyakarn V, Lin C.

PLoS One. 2015 May 26;10(5):e0123409. doi: 10.1371/journal.pone.0123409. eCollection 2015.


Reciprocal regulation of C-Maf tyrosine phosphorylation by Tec and Ptpn22.

Liu CC, Lai CY, Yen WF, Lin YH, Chang HH, Tai TS, Lu YJ, Tsao HW, Ho IC, Miaw SC.

PLoS One. 2015 May 20;10(5):e0127617. doi: 10.1371/journal.pone.0127617. eCollection 2015.


GaN-based photon-recycling green light-emitting diodes with vertical-conduction structure.

Sheu JK, Chen FB, Yen WY, Wang YC, Liu CN, Yeh YH, Lee ML.

Opt Express. 2015 Apr 6;23(7):A371-81. doi: 10.1364/OE.23.00A371.


Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.

Yen WC, Fischer MM, Axelrod F, Bond C, Cain J, Cancilla B, Henner WR, Meisner R, Sato A, Shah J, Tang T, Wallace B, Wang M, Zhang C, Kapoun AM, Lewicki J, Gurney A, Hoey T.

Clin Cancer Res. 2015 May 1;21(9):2084-95. doi: 10.1158/1078-0432.CCR-14-2808.


Ultrafast Graphene Growth on Insulators via Metal-Catalyzed Crystallization by a Laser Irradiation Process: From Laser Selection, Thickness Control to Direct Patterned Graphene Utilizing Controlled Layer Segregation Process.

Medina H, Huang CC, Lin HC, Huang YH, Chen YZ, Yen WC, Chueh YL.

Small. 2015 Jul 1;11(25):3017-27. doi: 10.1002/smll.201403463. Epub 2015 Mar 24.


miR-182 is largely dispensable for adaptive immunity: lack of correlation between expression and function.

Pucella JN, Yen WF, Kim MV, van der Veeken J, Luo CT, Socci ND, Naito Y, Li MO, Iwai N, Chaudhuri J.

J Immunol. 2015 Mar 15;194(6):2635-42. doi: 10.4049/jimmunol.1402261. Epub 2015 Feb 11. Erratum in: J Immunol. 2015 Aug 15;195(4):1903. Luo, Chong T [added].


Cocaine induces nuclear export and degradation of neuronal retinoid X receptor-γ via a TNF-α/JNK- mediated mechanism.

Kovalevich J, Yen W, Ozdemir A, Langford D.

J Neuroimmune Pharmacol. 2015 Mar;10(1):55-73. doi: 10.1007/s11481-014-9573-x. Epub 2015 Jan 14.


Endothelial surface glycocalyx can regulate flow-induced nitric oxide production in microvessels in vivo.

Yen W, Cai B, Yang J, Zhang L, Zeng M, Tarbell JM, Fu BM.

PLoS One. 2015 Jan 9;10(1):e0117133. doi: 10.1371/journal.pone.0117133. eCollection 2015.


A mesoporous silica biomaterial for dental biomimetic crystallization.

Chiang YC, Lin HP, Chang HH, Cheng YW, Tang HY, Yen WC, Lin PY, Chang KW, Lin CP.

ACS Nano. 2014 Dec 23;8(12):12502-13. doi: 10.1021/nn5053487. Epub 2014 Dec 11. Erratum in: ACS Nano. 2017 Feb 28;11(2):2305.


Diatomological investigation in sphenoid sinus fluid and lung tissue from cases of suspected drowning.

Lin CY, Yen WC, Hsieh HM, Tsai LC, Huang TY, Huang CC, Yu YJ, Shun CT, Wu JT, Chou CL, Linacre A, Lee JC.

Forensic Sci Int. 2014 Nov;244:111-5. doi: 10.1016/j.forsciint.2014.08.023. Epub 2014 Sep 3.


Wavefront sensorless adaptive optics temporal focusing-based multiphoton microscopy.

Chang CY, Cheng LC, Su HW, Hu YY, Cho KC, Yen WC, Xu C, Dong CY, Chen SJ.

Biomed Opt Express. 2014 May 9;5(6):1768-77. doi: 10.1364/BOE.5.001768. eCollection 2014 Jun 1.

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