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Progress of Brain Amyloid Deposition in Familial Alzheimer's Disease with Taiwan D678H APP Mutation.

Weng YC, Hsiao IT, Huang CY, Huang KL, Liu CH, Chang TY, Yen TC, Lin KJ, Huang CC.

J Alzheimers Dis. 2018 Oct 9. doi: 10.3233/JAD-180824. [Epub ahead of print]


Investigating the Association Between Advanced Practice Providers and Chemotherapy-Related Adverse Events in Women With Breast Cancer: A Nested Case-Control Study.

Yen TWF, Nattinger AB, McGinley EL, Fergestrom N, Pezzin LE, Laud PW.

J Oncol Pract. 2018 Oct 10:JOP1800277. doi: 10.1200/JOP.18.00277. [Epub ahead of print]


Pretreatment Primary Tumor and Nodal SUVmax Values on 18F-FDG PET/CT Images Predict Prognosis in Patients With Salivary Gland Carcinoma.

Hsieh CE, Cheng NM, Chou WC, Venkatesulu BP, Chou YC, Liao CT, Yen TC, Lin CY.

Clin Nucl Med. 2018 Sep 28. doi: 10.1097/RLU.0000000000002287. [Epub ahead of print]


Value of early evaluation of treatment response using 18F-FDG PET/CT parameters and the Epstein-Barr virus DNA load for prediction of outcome in patients with primary nasopharyngeal carcinoma.

Chen YH, Chang KP, Chu SC, Yen TC, Wang LY, Chang JT, Hsu CL, Ng SH, Liu SH, Chan SC.

Eur J Nucl Med Mol Imaging. 2018 Sep 27. doi: 10.1007/s00259-018-4172-3. [Epub ahead of print]


Functional Studies of Anodic Oxidized β-Ti-28Nb-11Ta-8Zr Alloy for Mechanical, In-vitro and Antibacterial Capability.

Lin HI, Kuo YM, Hu CC, Lee MH, Chen LH, Li CT, Wong TH, Yen TJ.

Sci Rep. 2018 Sep 24;8(1):14253. doi: 10.1038/s41598-018-32462-7.


Nodal failure patterns and utility of elective nodal irradiation in submandibular gland carcinoma treated with postoperative radiotherapy - a multicenter experience.

Hsieh CE, Lee LY, Chou YC, Fan KH, Tsang NM, Chang JT, Wang HM, Ng SH, Liao CT, Yen TC, Fang KH, Lin CY.

Radiat Oncol. 2018 Sep 21;13(1):184. doi: 10.1186/s13014-018-1130-y.


New Digital Plug and Imaging Sensor for a Proton Therapy Monitoring System Based on Positron Emission Tomography.

D'Ascenzo N, Gao M, Antonecchia E, Gnudi P, Chen HH, Chen FH, Hong JH, Hsiao IT, Yen TC, Wang W, Xi D, Zhang B, Xie Q.

Sensors (Basel). 2018 Sep 8;18(9). pii: E3006. doi: 10.3390/s18093006.


Solitary Extrahepatic Intramuscular Metastasis from Cryptogenic Hepatocellular Carcinoma.

Zubair T, Yen T, Gao G.

ACG Case Rep J. 2018 Sep 12;5:e64. doi: 10.14309/crj.2018.64. eCollection 2018.


Evaluation, Staging, and Surgical Management for Adrenocortical Carcinoma: An Update from the SSO Endocrine and Head and Neck Disease Site Working Group.

Dickson PV, Kim L, Yen TWF, Yang A, Grubbs EG, Patel D, Solórzano CC.

Ann Surg Oncol. 2018 Nov;25(12):3460-3468. doi: 10.1245/s10434-018-6749-2. Epub 2018 Sep 18.


Adjuvant and Neoadjuvant Therapy, Treatment for Advanced Disease, and Genetic Considerations for Adrenocortical Carcinoma: An Update from the SSO Endocrine and Head and Neck Disease Site Working Group.

Dickson PV, Kim L, Yen TWF, Yang A, Grubbs EG, Patel D, Solórzano CC.

Ann Surg Oncol. 2018 Sep 14. doi: 10.1245/s10434-018-6750-9. [Epub ahead of print]


Oncocytic papillary thyroid cancer has similar prognosis to matched classical papillary thyroid cancer controls.

Carr AA, Yen T, Ortiz DI, Hunt BC, Fareau G, Massey BL, Campbell BH, Doffek KL, Evans DB, Wang TS.

Thyroid. 2018 Sep 14. doi: 10.1089/thy.2017.0603. [Epub ahead of print]


Distinct psychopathology of patients who attempted suicide with rodenticide in Taiwan: a comparative study with patients of suicide with paraquat.

Lin C, Yen TH, Juang YY, Lee CP, Lee SH.

Psychol Res Behav Manag. 2018 Aug 29;11:323-328. doi: 10.2147/PRBM.S167621. eCollection 2018.


C-reactive protein levels can predict positive 18F-FDG PET/CT findings that lead to management changes in patients with bacteremia.

Tsai HY, Lee MH, Wan CH, Yang LY, Yen TC, Tseng JR.

J Microbiol Immunol Infect. 2018 Aug 23. pii: S1684-1182(18)30309-8. doi: 10.1016/j.jmii.2018.08.003. [Epub ahead of print]


Renal dysfunction increases the risk of recurrent stroke in patients with acute ischemic stroke.

Wang IK, Lien LM, Lee JT, Liu CH, Chen CH, Lin CH, Jeng JS, Hu CJ, Yen TH, Chen ST, Chiu HC, Tsai IJ, Sung FC, Hsu CY; Taiwan Stroke Registry Investigators.

Atherosclerosis. 2018 Oct;277:15-20. doi: 10.1016/j.atherosclerosis.2018.07.033. Epub 2018 Jul 27.


Focused Ultrasound-Induced Blood-Brain Barrier Opening Enhances GSK-3 Inhibitor Delivery for Amyloid-Beta Plaque Reduction.

Hsu PH, Lin YT, Chung YH, Lin KJ, Yang LY, Yen TC, Liu HL.

Sci Rep. 2018 Aug 27;8(1):12882. doi: 10.1038/s41598-018-31071-8.


SiNWs Biophysically Regulate the Fates of Human Mesenchymal Stem Cells.

Lin HI, Kuo SW, Yen TJ, Lee OK.

Sci Rep. 2018 Aug 27;8(1):12913. doi: 10.1038/s41598-018-30854-3.


Loss of ARID1A expression in endometrial samplings is associated with the risk of endometrial carcinoma.

Yen TT, Miyamoto T, Asaka S, Chui MH, Wang Y, Lin SF, Stone RL, Fader AN, Asaka R, Kashima H, Shiozawa T, Wang TL, Shih IM, Tanner EJ 3rd.

Gynecol Oncol. 2018 Sep;150(3):426-431. doi: 10.1016/j.ygyno.2018.06.025. Epub 2018 Jul 4.


Mineralocorticoid Receptor Antagonism Improves Parenchymal Arteriole Dilation Via a TRPV4-Dependent Mechanism and Prevents Cognitive Dysfunction in Hypertension.

Diaz-Otero JM, Yen TC, Fisher C, Bota D, Jackson WF, Dorrance AM.

Am J Physiol Heart Circ Physiol. 2018 Aug 17. doi: 10.1152/ajpheart.00207.2018. [Epub ahead of print]


Methylomic analysis of ovarian cancers identifies tumor-specific alterations readily detectable in early precursor lesions.

Pisanic TR, Cope L, Lin SF, Yen TT, Athamanolap P, Asaka R, Nakayama K, Fader AN, Wang TH, Shih IM, Wang TL.

Clin Cancer Res. 2018 Aug 14. pii: clincanres.1199.2018. doi: 10.1158/1078-0432.CCR-18-1199. [Epub ahead of print]


A postoperative parathyroid hormone-based algorithm to reduce symptomatic hypocalcemia following completion/total thyroidectomy: A retrospective analysis of 591 patients.

Mazotas IG, Yen TWF, Park J, Liu Y, Eastwood DC, Carr AA, Evans DB, Wang TS.

Surgery. 2018 Oct;164(4):746-753. doi: 10.1016/j.surg.2018.04.040. Epub 2018 Jul 30.


Targeting WEE1 to enhance conventional therapies for acute lymphoblastic leukemia.

Ghelli Luserna Di Rorà A, Beeharry N, Imbrogno E, Ferrari A, Robustelli V, Righi S, Sabattini E, Verga Falzacappa MV, Ronchini C, Testoni N, Baldazzi C, Papayannidis C, Abbenante MC, Marconi G, Paolini S, Parisi S, Sartor C, Fontana MC, De Matteis S, Iacobucci I, Pelicci PG, Cavo M, Yen TJ, Martinelli G.

J Hematol Oncol. 2018 Aug 1;11(1):99. doi: 10.1186/s13045-018-0641-1.


Prognostic model based on magnetic resonance imaging, whole-tumour apparent diffusion coefficient values and HPV genotyping for stage IB-IV cervical cancer patients following chemoradiotherapy.

Lin G, Yang LY, Lin YC, Huang YT, Liu FY, Wang CC, Lu HY, Chiang HJ, Chen YR, Wu RC, Ng KK, Hong JH, Yen TC, Lai CH.

Eur Radiol. 2018 Jul 26. doi: 10.1007/s00330-018-5651-4. [Epub ahead of print]


Proportional dose of rapid-onset opioid in breakthrough cancer pain management: An open-label, multicenter study.

Yen TY, Chiou JF, Chiang WY, Su WH, Huang MY, Hu MH, Wu SC, Lai YL.

Medicine (Baltimore). 2018 Jul;97(30):e11593. doi: 10.1097/MD.0000000000011593.


Presurgical Identification of Uterine Smooth Muscle Malignancies through the Characteristic FDG Uptake Pattern on PET Scans.

Ho KC, Dean Fang YH, Lin G, Ueng SH, Wu TI, Lai CH, Chueh HY, Chao A, Chang TC, Yen TC.

Contrast Media Mol Imaging. 2018 Jun 19;2018:7890241. doi: 10.1155/2018/7890241. eCollection 2018.


Visualization of ischemic stroke-related changes on 18F-THK-5351 positron emission tomography.

Huang KL, Hsu JL, Lin KJ, Chang CH, Wu YM, Chang TY, Chang YJ, Liu CH, Ho MY, Wey SP, Yen TC, Okamura N, Hsiao IT, Lee TH.

EJNMMI Res. 2018 Jul 16;8(1):62. doi: 10.1186/s13550-018-0417-1.


Effect of a Virtual Reality-Based Exercise Program on Fatigue in Hospitalized Taiwanese End-Stage Renal Disease Patients Undergoing Hemodialysis.

Chou HY, Chen SC, Yen TH, Han HM.

Clin Nurs Res. 2018 Jul 1:1054773818788511. doi: 10.1177/1054773818788511. [Epub ahead of print]


Detecting concurrent mood in daily contact networks: an online participatory cohort study with a diary approach.

Chan TC, Yen TJ, Hu TH, Fu YC, Hwang JS.

BMJ Open. 2018 Jul 10;8(7):e020600. doi: 10.1136/bmjopen-2017-020600.


Comparative health risk of inhaled exposure to organic solvents, toxic metals, and hexavalent chromium from the use of spray paints in Taiwan.

Lin CH, Lai CH, Peng YP, Wu PC, Chuang KY, Yen TY, Xiang YK.

Environ Sci Pollut Res Int. 2018 Jul 4. doi: 10.1007/s11356-018-2669-8. [Epub ahead of print]


A pilot study investigating the in vitro efficacy of sucralfate against common veterinary cutaneous pathogens.

Yen T, Boord MJ, Ghubash R, Blondeau JM.

J Small Anim Pract. 2018 Jul 4. doi: 10.1111/jsap.12902. [Epub ahead of print]


Dietary Leucine Supplement Ameliorates Hepatic Steatosis and Diabetic Nephropathy in db/db Mice.

Chen KH, Chen YL, Tang HY, Hung CC, Yen TH, Cheng ML, Shiao MS, Chen JK.

Int J Mol Sci. 2018 Jun 30;19(7). pii: E1921. doi: 10.3390/ijms19071921.


Diversity of neurodegenerative pathophysiology in nondemented patients with major depressive disorder: Evidence of cerebral amyloidosis and hippocampal atrophy.

Wu KY, Lin KJ, Chen CH, Chen CS, Liu CY, Huang SY, Yen TC, Hsiao IT.

Brain Behav. 2018 Jul;8(7):e01016. doi: 10.1002/brb3.1016. Epub 2018 Jun 21.


Uremic Pruritus is Associated with Two-Year Cardiovascular Mortality in Long Term Hemodialysis Patients.

Weng CH, Hu CC, Yen TH, Hsu CW, Huang WH.

Kidney Blood Press Res. 2018;43(3):1000-1009. doi: 10.1159/000490689. Epub 2018 Jun 15.


Metabolic risk factors are associated with non-hepatitis B non-hepatitis C hepatocellular carcinoma in Taiwan, an endemic area of chronic hepatitis B.

Huang SF, Chang IC, Hong CC, Yen TC, Chen CL, Wu CC, Tsai CC, Ho MC, Lee WC, Yu HC, Shen YY, Eng HL, Wang J, Tseng HH, Jeng YM, Yeh CT, Chen CL, Chen PJ, Liaw YF.

Hepatol Commun. 2018 Apr 18;2(6):747-759. doi: 10.1002/hep4.1182. eCollection 2018 Jun.


A phase II randomized trial comparing neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in advanced squamous cell carcinoma of the pharynx or larynx.

Huang PW, Lin CY, Hsieh CH, Hsu CL, Fan KH, Huang SF, Liao CT, Ng SK, Yen TC, Chang JT, Wang HM.

Biomed J. 2018 Apr;41(2):129-136. doi: 10.1016/ Epub 2018 May 21.


Evolution of archaeal Rib7 and eubacterial RibG reductases in riboflavin biosynthesis: Substrate specificity and cofactor preference.

Chen SC, Yen TM, Chang TH, Liaw SH.

Biochem Biophys Res Commun. 2018 Sep 3;503(1):195-201. doi: 10.1016/j.bbrc.2018.06.002. Epub 2018 Jun 8.


Intrahepatic hepatitis B virus large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis.

Li TN, Wu YJ, Tsai HW, Sun CP, Wu YH, Wu HL, Pei YN, Lu KY, Yen TT, Chang CW, Chan HL, Tao MH, Liou JY, Chang MD, Su IJ, Wang LH.

J Pathol. 2018 Aug;245(4):502-513. doi: 10.1002/path.5102. Epub 2018 Jul 4.


Prognostic significance of combined pretreatment lymphocyte counts and body mass index in patients with head and neck cancer treated with radiation therapy.

Wu YY, Chang KP, Lin CY, Pai PC, Wang HM, Hsu CL, Liao CT, Yen TC, Fang TJ, Huang SF, Kang CJ, Fang KH, Lin WN, Wang YC, Hsin LJ, Tsang NM.

Cancer Med. 2018 May 23. doi: 10.1002/cam4.1489. [Epub ahead of print]


Role of nutritional vitamin D in osteoporosis treatment.

Hou YC, Wu CC, Liao MT, Shyu JF, Hung CF, Yen TH, Lu CL, Lu KC.

Clin Chim Acta. 2018 Sep;484:179-191. doi: 10.1016/j.cca.2018.05.035. Epub 2018 May 18. Review.


Results of a real-world study on vortioxetine in patients with major depressive disorder in South East Asia (REVIDA).

Chin CN, Zain A, Hemrungrojn S, Ung EK, Kwansanit P, Au Yong KC, Chong MSW, Inpa C, Yen TH, Yeoh BBD, Tay LK, Bernardo C, Lim LC, Yap CH, Fones C, Nayak A, Nelleman L.

Curr Med Res Opin. 2018 Nov;34(11):1975-1984. doi: 10.1080/03007995.2018.1477746. Epub 2018 Jun 14.


The role of adjuvant treatment in early-stage oral cavity squamous cell carcinoma: An international collaborative study.

Fridman E, Na'ara S, Agarwal J, Amit M, Bachar G, Villaret AB, Brandao J, Cernea CR, Chaturvedi P, Clark J, Ebrahimi A, Fliss DM, Jonnalagadda S, Kohler HF, Kowalski LP, Kreppel M, Liao CT, Patel SG, Patel RS, Robbins KT, Shah JP, Shpitzer T, Yen TC, Zöller JE, Gil Z; International Consortium for Outcome Research in Head and Neck Cancer.

Cancer. 2018 Jul 15;124(14):2948-2955. doi: 10.1002/cncr.31531. Epub 2018 May 14.


Synergistic antiproliferative effects of an mTOR inhibitor (rad001) plus gemcitabine on cholangiocarcinoma by decreasing choline kinase activity.

Lin G, Lin KJ, Wang F, Chen TC, Yen TC, Yeh TS.

Dis Model Mech. 2018 May 14;11(8). pii: dmm033050. doi: 10.1242/dmm.033050.


Narcotics reduction, quality and safety in gynecologic oncology surgery in the first year of enhanced recovery after surgery protocol implementation.

Bergstrom JE, Scott ME, Alimi Y, Yen TT, Hobson D, Machado KK, Tanner EJ 3rd, Fader AN, Temkin SM, Wethington S, Levinson K, Sokolinsky S, Lau B, Stone RL.

Gynecol Oncol. 2018 Jun;149(3):554-559. doi: 10.1016/j.ygyno.2018.04.003. Epub 2018 Apr 13.


Neuroprotective Effects of Platonin, a Therapeutic Immunomodulating Medicine, on Traumatic Brain Injury in Mice after Controlled Cortical Impact.

Yen TL, Chang CC, Chung CL, Ko WC, Yang CH, Hsieh CY.

Int J Mol Sci. 2018 Apr 6;19(4). pii: E1100. doi: 10.3390/ijms19041100.


Pretreatment subcutaneous adipose tissue predicts the outcomes of patients with head and neck cancer receiving definitive radiation and chemoradiation in Taiwan.

Pai PC, Chuang CC, Chuang WC, Tsang NM, Tseng CK, Chen KH, Yen TC, Lin CY, Chang KP, Lei KF.

Cancer Med. 2018 May;7(5):1630-1641. doi: 10.1002/cam4.1365. Epub 2018 Apr 2.


Methotrexate sensitizes drug-resistant metastatic melanoma cells to BRAF V600E inhibitors dabrafenib and encorafenib.

Ross KC, Chin KF, Kim D, Marion CD, Yen TJ, Bhattacharjee V.

Oncotarget. 2018 Jan 29;9(17):13324-13336. doi: 10.18632/oncotarget.24341. eCollection 2018 Mar 2.


Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers.

Wang Y, Li L, Douville C, Cohen JD, Yen TT, Kinde I, Sundfelt K, Kjær SK, Hruban RH, Shih IM, Wang TL, Kurman RJ, Springer S, Ptak J, Popoli M, Schaefer J, Silliman N, Dobbyn L, Tanner EJ, Angarita A, Lycke M, Jochumsen K, Afsari B, Danilova L, Levine DA, Jardon K, Zeng X, Arseneau J, Fu L, Diaz LA Jr, Karchin R, Tomasetti C, Kinzler KW, Vogelstein B, Fader AN, Gilbert L, Papadopoulos N.

Sci Transl Med. 2018 Mar 21;10(433). pii: eaap8793. doi: 10.1126/scitranslmed.aap8793.


Correction: Multiparametric imaging using 18F-FDG PET/CT heterogeneity parameters and functional MRI techniques: prognostic significance in patients with primary advanced oropharyngeal or hypopharyngeal squamous cell carcinoma treated with chemoradiotherapy.

Chan SC, Cheng NM, Hsieh CH, Ng SH, Lin CY, Yen TC, Hsu CL, Wan HM, Liao CT, Chang KP, Wang JJ.

Oncotarget. 2018 Feb 9;9(11):10184. doi: 10.18632/oncotarget.24463. eCollection 2018 Feb 9.


Clinical utility of simultaneous whole-body 18F-FDG PET/MRI as a single-step imaging modality in the staging of primary nasopharyngeal carcinoma.

Chan SC, Yeh CH, Yen TC, Ng SH, Chang JT, Lin CY, Yen-Ming T, Fan KH, Huang BS, Hsu CL, Chang KP, Wang HM, Liao CT.

Eur J Nucl Med Mol Imaging. 2018 Jul;45(8):1297-1308. doi: 10.1007/s00259-018-3986-3. Epub 2018 Mar 3.


Human papillomavirus infection is not associated with laryngeal squamous cell carcinoma in Taiwan.

Huang CG, Lee LA, Fang TJ, Li HY, Liao CT, Kang CJ, Yen TC, Tsao KC, Chen TC, Shih SR.

J Microbiol Immunol Infect. 2018 Feb 21. pii: S1684-1182(18)30047-1. doi: 10.1016/j.jmii.2018.02.002. [Epub ahead of print]

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