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Items: 18


Summary of the 2017 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

Hulsebus HJ, Curtis BJ, Molina PE, Afshar M, Boule LA, Morris N, Keshavarzian A, Kolls JK, Yeligar SM, Price ME, Wyatt TA, Choudhry MA, Kovacs EJ.

Alcohol. 2018 Jun;69:51-56. doi: 10.1016/j.alcohol.2017.10.006. Epub 2017 Oct 31. Review.


Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer.

Paredes F, Sheldon K, Lassègue B, Williams HC, Faidley EA, Benavides GA, Torres G, Sanhueza-Olivares F, Yeligar SM, Griendling KK, Darley-Usmar V, San Martin A.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1789-1794. doi: 10.1073/pnas.1720693115. Epub 2018 Feb 6.


TGF-β1 Suppresses the Type I IFN Response and Induces Mitochondrial Dysfunction in Alveolar Macrophages.

Grunwell JR, Yeligar SM, Stephenson S, Ping XD, Gauthier TW, Fitzpatrick AM, Brown LAS.

J Immunol. 2018 Mar 15;200(6):2115-2128. doi: 10.4049/jimmunol.1701325. Epub 2018 Feb 2.


PPARγ Regulates Mitochondrial Structure and Function and Human Pulmonary Artery Smooth Muscle Cell Proliferation.

Yeligar SM, Kang BY, Bijli KM, Kleinhenz JM, Murphy TC, Torres G, San Martin A, Sutliff RL, Hart CM.

Am J Respir Cell Mol Biol. 2018 May;58(5):648-657. doi: 10.1165/rcmb.2016-0293OC.


Dysregulation of Alveolar Macrophage PPARγ, NADPH Oxidases, and TGFβ1 in Otherwise Healthy HIV-Infected Individuals.

Yeligar SM, Ward JM, Harris FL, Brown LAS, Guidot DM, Cribbs SK.

AIDS Res Hum Retroviruses. 2017 Oct;33(10):1018-1026. doi: 10.1089/AID.2016.0030. Epub 2017 Apr 24.


Alcohol and lung injury and immunity.

Yeligar SM, Chen MM, Kovacs EJ, Sisson JH, Burnham EL, Brown LA.

Alcohol. 2016 Sep;55:51-59. doi: 10.1016/j.alcohol.2016.08.005. Epub 2016 Sep 16. Review.


Alcohol and inflammatory responses: Highlights of the 2015 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

Cannon AR, Morris NL, Hammer AM, Curtis B, Remick DG, Yeligar SM, Poole L, Burnham EL, Wyatt TA, Molina PE, So-Armah K, Cisneros T, Wang G, Lang CH, Mandrekar P, Kovacs EJ, Choudhry MA.

Alcohol. 2016 Aug;54:73-7. doi: 10.1016/j.alcohol.2016.06.005. Epub 2016 Jul 25.


Peroxisome Proliferator-Activated Receptor γ Regulates Chronic Alcohol-Induced Alveolar Macrophage Dysfunction.

Yeligar SM, Mehta AJ, Harris FL, Brown LA, Hart CM.

Am J Respir Cell Mol Biol. 2016 Jul;55(1):35-46. doi: 10.1165/rcmb.2015-0077OC.


Peroxisome Proliferator-Activated Receptor γ and microRNA 98 in Hypoxia-Induced Endothelin-1 Signaling.

Kang BY, Park KK, Kleinhenz JM, Murphy TC, Green DE, Bijli KM, Yeligar SM, Carthan KA, Searles CD, Sutliff RL, Hart CM.

Am J Respir Cell Mol Biol. 2016 Jan;54(1):136-46. doi: 10.1165/rcmb.2014-0337OC.


Glutathione attenuates ethanol-induced alveolar macrophage oxidative stress and dysfunction by downregulating NADPH oxidases.

Yeligar SM, Harris FL, Hart CM, Brown LA.

Am J Physiol Lung Cell Mol Physiol. 2014 Mar 1;306(5):L429-41. doi: 10.1152/ajplung.00159.2013. Epub 2014 Jan 17.


Alcoholism causes alveolar macrophage zinc deficiency and immune dysfunction.

Mehta AJ, Yeligar SM, Elon L, Brown LA, Guidot DM.

Am J Respir Crit Care Med. 2013 Sep 15;188(6):716-23. doi: 10.1164/rccm.201301-0061OC.


Exhaled breath condensate: a promising source for biomarkers of lung disease.

Liang Y, Yeligar SM, Brown LA.

ScientificWorldJournal. 2012;2012:217518. doi: 10.1100/2012/217518. Epub 2012 Dec 17.


Chronic-alcohol-abuse-induced oxidative stress in the development of acute respiratory distress syndrome.

Liang Y, Yeligar SM, Brown LA.

ScientificWorldJournal. 2012;2012:740308. doi: 10.1100/2012/740308. Epub 2012 Dec 27.


Ethanol induces oxidative stress in alveolar macrophages via upregulation of NADPH oxidases.

Yeligar SM, Harris FL, Hart CM, Brown LA.

J Immunol. 2012 Apr 15;188(8):3648-57. doi: 10.4049/jimmunol.1101278. Epub 2012 Mar 12.


PPARγ ligands regulate NADPH oxidase, eNOS, and barrier function in the lung following chronic alcohol ingestion.

Wagner MC, Yeligar SM, Brown LA, Michael Hart C.

Alcohol Clin Exp Res. 2012 Feb;36(2):197-206. doi: 10.1111/j.1530-0277.2011.01599.x. Epub 2011 Jul 18.


Ethanol-induced HO-1 and NQO1 are differentially regulated by HIF-1alpha and Nrf2 to attenuate inflammatory cytokine expression.

Yeligar SM, Machida K, Kalra VK.

J Biol Chem. 2010 Nov 12;285(46):35359-73. doi: 10.1074/jbc.M110.138636. Epub 2010 Sep 10.


Ethanol augments RANTES/CCL5 expression in rat liver sinusoidal endothelial cells and human endothelial cells via activation of NF-kappa B, HIF-1 alpha, and AP-1.

Yeligar SM, Machida K, Tsukamoto H, Kalra VK.

J Immunol. 2009 Nov 1;183(9):5964-76. doi: 10.4049/jimmunol.0901564. Epub 2009 Oct 14.


Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression.

Wang Z, Lecane PS, Thiemann P, Fan Q, Cortez C, Ma X, Tonev D, Miles D, Naumovski L, Miller RA, Magda D, Cho DG, Sessler JL, Pike BL, Yeligar SM, Karaman MW, Hacia JG.

Mol Cancer. 2007 Jan 19;6:9.

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