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Items: 17

1.

Selective inhibition of eosinophil influx into the lung by small molecule CC chemokine receptor 3 antagonists in mouse models of allergic inflammation.

Das AM, Vaddi KG, Solomon KA, Krauthauser C, Jiang X, McIntyre KW, Yang XX, Wadman E, Welch P, Covington M, Graden D, Yeleswaram K, Trzaskos JM, Newton RC, Mandlekar S, Ko SS, Carter PH, Davies P.

J Pharmacol Exp Ther. 2006 Jul;318(1):411-7. Epub 2006 Apr 13.

PMID:
16614169
2.

The chimpanzee (Pan troglodytes) as a pharmacokinetic model for selection of drug candidates: model characterization and application.

Wong H, Grossman SJ, Bai SA, Diamond S, Wright MR, Grace JE Jr, Qian M, He K, Yeleswaram K, Christ DD.

Drug Metab Dispos. 2004 Dec;32(12):1359-69. Epub 2004 Aug 27.

PMID:
15333515
3.

Heterocyclic aminopyrrolidine derivatives as melatoninergic agents.

Sun LQ, Chen J, Mattson RJ, Epperson JR, Deskus JA, Li WS, Takaki K, Hodges DB, Iben L, Mahle CD, Ortiz A, Molstad D, Ryan E, Yeleswaram K, Xu C, Luo G.

Bioorg Med Chem Lett. 2003 Dec 15;13(24):4381-4.

PMID:
14643330
4.

Preclinical pharmacokinetics and metabolism of BMS-214778, a novel melatonin receptor agonist.

Vachharajani NN, Yeleswaram K, Boulton DW.

J Pharm Sci. 2003 Apr;92(4):760-72.

PMID:
12661062
5.

The synthesis and characterization of BMS-204352 (MaxiPost) and related 3-fluorooxindoles as openers of maxi-K potassium channels.

Hewawasam P, Gribkoff VK, Pendri Y, Dworetzky SI, Meanwell NA, Martinez E, Boissard CG, Post-Munson DJ, Trojnacki JT, Yeleswaram K, Pajor LM, Knipe J, Gao Q, Perrone R, Starrett JE Jr.

Bioorg Med Chem Lett. 2002 Apr 8;12(7):1023-6.

PMID:
11909708
6.

Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels.

Gribkoff VK, Starrett JE Jr, Dworetzky SI, Hewawasam P, Boissard CG, Cook DA, Frantz SW, Heman K, Hibbard JR, Huston K, Johnson G, Krishnan BS, Kinney GG, Lombardo LA, Meanwell NA, Molinoff PB, Myers RA, Moon SL, Ortiz A, Pajor L, Pieschl RL, Post-Munson DJ, Signor LJ, Srinivas N, Taber MT, Thalody G, Trojnacki JT, Wiener H, Yeleswaram K, Yeola SW.

Nat Med. 2001 Apr;7(4):471-7.

PMID:
11283675
7.

Involvement of cytochrome P-450 isozymes in melatonin metabolism and clinical implications.

Yeleswaram K, Vachharajani N, Santone K.

J Pineal Res. 1999 Apr;26(3):190-1. No abstract available.

PMID:
10231734
8.

Comment on "Pharmacokinetic interaction between cyclosporine and the dihydropyridine calcium antagonist felodipine".

Yeleswaram K.

Eur J Clin Pharmacol. 1997;52(2):159, 161. No abstract available.

PMID:
9174687
9.

Pharmacokinetics and oral bioavailability of exogenous melatonin in preclinical animal models and clinical implications.

Yeleswaram K, McLaughlin LG, Knipe JO, Schabdach D.

J Pineal Res. 1997 Jan;22(1):45-51.

PMID:
9062870
10.

In vivo disposition and in vitro metabolism of an anxiolytic compound, BMS-184111, in rats.

Yeleswaram K, Volk KJ, Rourick R, Catt JD, Mattson RJ, McGoff KB, Knipe JO.

Res Commun Mol Pathol Pharmacol. 1995 Jul;89(1):27-44.

PMID:
7582859
11.

Relevance of tissue distribution studies.

Yeleswaram K.

Drug Metab Dispos. 1995 Feb;23(2):159. No abstract available.

PMID:
7736905
12.

Transplacental and nonplacental clearances, metabolism and pharmacodynamics of labetalol in the fetal lamb after direct intravenous administration.

Yeleswaram K, Rurak DW, Kwan E, Hall C, Doroudian A, Wright MR, Abbott FS, Axelson JE.

J Pharmacol Exp Ther. 1993 Oct;267(1):425-31.

PMID:
8229771
13.
14.

Disposition, metabolism, and pharmacodynamics of labetalol in adult sheep.

Yeleswaram K, Rurak DW, Kwan E, Hall C, Doroudian A, Abbott FS, Axelson JE.

Drug Metab Dispos. 1993 Mar-Apr;21(2):284-92.

PMID:
8097698
15.

Identification and quantitation of an oxidative metabolite of labetalol in sheep: pharmacokinetic and metabolic implications.

Yeleswaram K, Rurak DW, Kwan E, Hall C, Abbott FS, Axelson JE.

Biol Mass Spectrom. 1992 Nov;21(11):534-40.

PMID:
1457468
16.

Pharmacokinetics and pharmacodynamics of labetalol in the pregnant sheep.

Yeleswaram K, Rurak DW, Hall C, Wright MR, Axelson JE.

J Pharmacol Exp Ther. 1992 Aug;262(2):683-91.

PMID:
1501116
17.

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