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Items: 1 to 50 of 192


Correction: SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling.

Jiang L, Han X, Wang J, Wang C, Sun X, Xie J, Wu G, Phan H, Liu Z, Yeh ETH, Zhang C, Zhao M, Kang X.

J Exp Med. 2018 Aug 6;215(8):2227. doi: 10.1084/jem.2017147706252018c. Epub 2018 Jul 13. No abstract available.


sNASP inhibits TLR signaling to regulate immune response in sepsis.

Yang FM, Zuo Y, Zhou W, Xia C, Hahm B, Sullivan M, Cheng J, Chang HM, Yeh ET.

J Clin Invest. 2018 Jun 1;128(6):2459-2472. doi: 10.1172/JCI95720. Epub 2018 May 7.


SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling.

Jiang L, Han X, Wang J, Wang C, Sun X, Xie J, Wu G, Phan H, Liu Z, Yeh ETH, Zhang C, Zhao M, Kang X.

J Exp Med. 2018 May 7;215(5):1337-1347. doi: 10.1084/jem.20171477. Epub 2018 Apr 18. Erratum in: J Exp Med. 2018 Aug 6;215(8):2227.


Publisher Correction: Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway.

Li J, Lu D, Dou H, Liu H, Weaver K, Wang W, Li J, Yeh ETH, Williams BO, Zheng L, Yang T.

Nat Commun. 2018 Feb 8;9(1):646. doi: 10.1038/s41467-018-03177-0.


DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.

Lao Y, Yang K, Wang Z, Sun X, Zou Q, Yu X, Cheng J, Tong X, Yeh ETH, Yang J, Yi J.

J Biol Chem. 2018 Mar 16;293(11):3965-3980. doi: 10.1074/jbc.M117.816769. Epub 2018 Jan 19.


Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway.

Li J, Lu D, Dou H, Liu H, Weaver K, Wang W, Li J, Yeh ETH, Williams BO, Zheng L, Yang T.

Nat Commun. 2018 Jan 10;9(1):143. doi: 10.1038/s41467-017-02413-3. Erratum in: Nat Commun. 2018 Feb 8;9(1):646.


Cardiovascular Complications of Cancer Therapy: Best Practices in Diagnosis, Prevention, and Management: Part 2.

Chang HM, Okwuosa TM, Scarabelli T, Moudgil R, Yeh ETH.

J Am Coll Cardiol. 2017 Nov 14;70(20):2552-2565. doi: 10.1016/j.jacc.2017.09.1095. Review.


Cardiovascular Complications of Cancer Therapy: Best Practices in Diagnosis, Prevention, and Management: Part 1.

Chang HM, Moudgil R, Scarabelli T, Okwuosa TM, Yeh ETH.

J Am Coll Cardiol. 2017 Nov 14;70(20):2536-2551. doi: 10.1016/j.jacc.2017.09.1096. Review. Erratum in: J Am Coll Cardiol. 2018 Feb 6;71(5):587.


Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2.

Wang R, Liu F, Zhao Y, Wu D, Chen L, Yeh ETH, Huang C.

Oncotarget. 2017 Jul 26;8(41):70142-70155. doi: 10.18632/oncotarget.19594. eCollection 2017 Sep 19.


Cancer and Clot: Between a Rock and a Hard Place.

Yeh ETH, Chang HM.

J Am Coll Cardiol. 2017 Aug 22;70(8):939-941. doi: 10.1016/j.jacc.2017.07.719. No abstract available.


Potential of Oncocardiology-Reply.

Chang HM, Yeh ETH.

JAMA Cardiol. 2017 Jul 1;2(7):818. doi: 10.1001/jamacardio.2017.0122. No abstract available.


SENP1 regulates PTEN stability to dictate prostate cancer development.

Bawa-Khalfe T, Yang FM, Ritho J, Lin HK, Cheng J, Yeh ET.

Oncotarget. 2017 Mar 14;8(11):17651-17664. doi: 10.18632/oncotarget.13283.


The Future of Onco-Cardiology: We Are Not Just "Side Effect Hunters".

Abe J, Martin JF, Yeh ET.

Circ Res. 2016 Sep 30;119(8):896-9. doi: 10.1161/CIRCRESAHA.116.309573. Review. No abstract available.


Oncocardiology-Past, Present, and Future: A Review.

Yeh ET, Chang HM.

JAMA Cardiol. 2016 Dec 1;1(9):1066-1072. doi: 10.1001/jamacardio.2016.2132.


China's ecosystems: Sacrificing the poor.

Zinda JA, Hopping KA, Schmitt E, Yeh ET, Harrell S, Anderson EN.

Science. 2016 Aug 12;353(6300):657-8. doi: 10.1126/science.aah4960. No abstract available.


SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer.

Zhou Z, Wang M, Li J, Xiao M, Chin YE, Cheng J, Yeh ET, Yang J, Yi J.

Oncogene. 2016 Nov 10;35(45):5826-5838. doi: 10.1038/onc.2016.124. Epub 2016 May 16.


Mechanisms of Cardiotoxicity of Cancer Chemotherapeutic Agents: Cardiomyopathy and Beyond.

Moudgil R, Yeh ET.

Can J Cardiol. 2016 Jul;32(7):863-870.e5. doi: 10.1016/j.cjca.2016.01.027. Epub 2016 Feb 2. Review.


The Utility of Point-of-Care Biomarkers to Detect Cardiotoxicity During Anthracycline Chemotherapy: A Feasibility Study.

Lenihan DJ, Stevens PL, Massey M, Plana JC, Araujo DM, Fanale MA, Fayad LE, Fisch MJ, Yeh ET.

J Card Fail. 2016 Jun;22(6):433-8. doi: 10.1016/j.cardfail.2016.04.003. Epub 2016 Apr 11.


SUMOylated ORC2 Recruits a Histone Demethylase to Regulate Centromeric Histone Modification and Genomic Stability.

Huang C, Cheng J, Bawa-Khalfe T, Yao X, Chin YE, Yeh ETH.

Cell Rep. 2016 Apr 5;15(1):147-157. doi: 10.1016/j.celrep.2016.02.091. Epub 2016 Mar 24.


Withdrawal of Heart Failure Medications in Cancer Survivors With Chemotherapy-Induced Left Ventricular Dysfunction: A Pilot Study.

Fadol AP, Banchs J, Hassan SA, Yeh ET, Fellman B.

J Card Fail. 2016 Jun;22(6):481-2. doi: 10.1016/j.cardfail.2016.03.011. Epub 2016 Mar 29. No abstract available.


Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells.

Ferdaoussi M, Dai X, Jensen MV, Wang R, Peterson BS, Huang C, Ilkayeva O, Smith N, Miller N, Hajmrle C, Spigelman AF, Wright RC, Plummer G, Suzuki K, Mackay JP, van de Bunt M, Gloyn AL, Ryan TE, Norquay LD, Brosnan MJ, Trimmer JK, Rolph TP, Kibbey RG, Manning Fox JE, Colmers WF, Shirihai OS, Neufer PD, Yeh ET, Newgard CB, MacDonald PE.

J Clin Invest. 2015 Oct 1;125(10):3847-60. doi: 10.1172/JCI82498. Epub 2015 Sep 21.


A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress.

Ritho J, Arold ST, Yeh ET.

Cell Rep. 2015 Aug 4;12(5):734-42. doi: 10.1016/j.celrep.2015.07.002. Epub 2015 Jul 23.


Subclinical Cardiotoxicity Associated With Cancer Therapy: Early Detection and Future Directions.

Yeh ET, Vejpongsa P.

J Am Coll Cardiol. 2015 Jun 16;65(23):2523-5. doi: 10.1016/j.jacc.2015.04.012. No abstract available.


Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function.

Heo KS, Le NT, Cushman HJ, Giancursio CJ, Chang E, Woo CH, Sullivan MA, Taunton J, Yeh ET, Fujiwara K, Abe J.

J Clin Invest. 2015 Mar 2;125(3):1299-310. doi: 10.1172/JCI76453. Epub 2015 Feb 17.


Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy.

Cai R, Gu J, Sun H, Liu X, Mei W, Qi Y, Xue S, Ren S, Rabinowitz JE, Wang Y, Yeh ET, Cheng J.

J Mol Cell Cardiol. 2015 Feb;79:115-22. doi: 10.1016/j.yjmcc.2014.11.014. Epub 2014 Nov 21.


De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells.

Ren YH, Liu KJ, Wang M, Yu YN, Yang K, Chen Q, Yu B, Wang W, Li QW, Wang J, Hou ZY, Fang JY, Yeh ET, Yang J, Yi J.

Oncotarget. 2014 Aug 30;5(16):7093-104.


Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death.

Qi Y, Wang J, Bomben VC, Li DP, Chen SR, Sun H, Xi Y, Reed JG, Cheng J, Pan HL, Noebels JL, Yeh ET.

Neuron. 2014 Sep 3;83(5):1159-71. doi: 10.1016/j.neuron.2014.07.042.


Prevention of anthracycline-induced cardiotoxicity: challenges and opportunities.

Vejpongsa P, Yeh ET.

J Am Coll Cardiol. 2014 Sep 2;64(9):938-45. doi: 10.1016/j.jacc.2014.06.1167. Review.


Report on the international colloquium on cardio-oncology (rome, 12-14 march 2014).

Ewer M, Gianni L, Pane F, Sandri MT, Steiner RK, Wojnowski L, Yeh ET, Carver JR, Lipshultz SE, Minotti G, Armstrong GT, Cardinale D, Colan SD, Darby SC, Force TL, Kremer LC, Lenihan DJ, Sallan SE, Sawyer DB, Suter TM, Swain SM, van Leeuwen FE.

Ecancermedicalscience. 2014 May 29;8:433. doi: 10.3332/ecancer.2014.433. eCollection 2014.


Wrestling with heart failure: SUMO-1 to the rescue.

Vejpongsa P, Yeh ET.

Circ Res. 2014 May 9;114(10):1561-3. doi: 10.1161/CIRCRESAHA.114.304125. No abstract available.


An essential role of small ubiquitin-like modifier (SUMO)-specific Protease 2 in myostatin expression and myogenesis.

Qi Y, Zuo Y, Yeh ET, Cheng J.

J Biol Chem. 2014 Feb 7;289(6):3288-93. doi: 10.1074/jbc.M113.518282. Epub 2013 Dec 16.


Topoisomerase 2β: a promising molecular target for primary prevention of anthracycline-induced cardiotoxicity.

Vejpongsa P, Yeh ET.

Clin Pharmacol Ther. 2014 Jan;95(1):45-52. doi: 10.1038/clpt.2013.201. Epub 2013 Oct 3. Review.


Emerging paradigms in cardiomyopathies associated with cancer therapies.

Ky B, Vejpongsa P, Yeh ET, Force T, Moslehi JJ.

Circ Res. 2013 Aug 30;113(6):754-64. doi: 10.1161/CIRCRESAHA.113.300218. Review.


De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis.

Heo KS, Chang E, Le NT, Cushman H, Yeh ET, Fujiwara K, Abe J.

Circ Res. 2013 Mar 15;112(6):911-23. doi: 10.1161/CIRCRESAHA.111.300179. Epub 2013 Feb 4.


Targeting constitutively activated β1 integrins inhibits prostate cancer metastasis.

Lee YC, Jin JK, Cheng CJ, Huang CF, Song JH, Huang M, Brown WS, Zhang S, Yu-Lee LY, Yeh ET, McIntyre BW, Logothetis CJ, Gallick GE, Lin SH.

Mol Cancer Res. 2013 Apr;11(4):405-17. doi: 10.1158/1541-7786.MCR-12-0551. Epub 2013 Jan 21.


SUMO-specific protease 1 regulates mitochondrial biogenesis through PGC-1α.

Cai R, Yu T, Huang C, Xia X, Liu X, Gu J, Xue S, Yeh ET, Cheng J.

J Biol Chem. 2012 Dec 28;287(53):44464-70. doi: 10.1074/jbc.M112.422626. Epub 2012 Nov 14.


Cytokine profile and ST-elevation myocardial infarction.

Willerson JT, Yeh ET, Perin EC.

Circ Res. 2012 Oct 26;111(10):1256-7. doi: 10.1161/CIRCRESAHA.112.279380. No abstract available.


Identification of the molecular basis of doxorubicin-induced cardiotoxicity.

Zhang S, Liu X, Bawa-Khalfe T, Lu LS, Lyu YL, Liu LF, Yeh ET.

Nat Med. 2012 Nov;18(11):1639-42. doi: 10.1038/nm.2919. Epub 2012 Oct 28.


Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition.

Bawa-Khalfe T, Lu LS, Zuo Y, Huang C, Dere R, Lin FM, Yeh ET.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17466-71. doi: 10.1073/pnas.1209378109. Epub 2012 Oct 8.


Heparin and bone marrow-derived cell therapy: friend or foe?

Yeh ET, Willerson JT.

Circ Res. 2012 Sep 14;111(7):819-20. doi: 10.1161/CIRCRESAHA.112.277517. No abstract available.


SUMO-specific protease 1 promotes prostate cancer progression and metastasis.

Wang Q, Xia N, Li T, Xu Y, Zou Y, Zuo Y, Fan Q, Bawa-Khalfe T, Yeh ET, Cheng J.

Oncogene. 2013 May 9;32(19):2493-8. doi: 10.1038/onc.2012.250. Epub 2012 Jun 25.


SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation.

Van Nguyen T, Angkasekwinai P, Dou H, Lin FM, Lu LS, Cheng J, Chin YE, Dong C, Yeh ET.

Mol Cell. 2012 Jan 27;45(2):210-21. doi: 10.1016/j.molcel.2011.12.026.


Weighing in on heart failure: the role of SERCA2a SUMOylation.

Schwartz RJ, Yeh ET.

Circ Res. 2012 Jan 20;110(2):198-9. doi: 10.1161/RES.0b013e318246f187. No abstract available.


Microphthalmia-associated transcription factor, melanoma, and renal carcinoma: the small ubiquitin-like modifier connection.

Yeh ET.

Pigment Cell Melanoma Res. 2011 Dec;24(6):1079-80. doi: 10.1111/j.1755-148X.2011.00925.x. No abstract available.


Molecular imaging of mesenchymal stem cell: mechanistic insight into cardiac repair after experimental myocardial infarction.

Wang J, Najjar A, Zhang S, Rabinovich B, Willerson JT, Gelovani JG, Yeh ET.

Circ Cardiovasc Imaging. 2012 Jan;5(1):94-101. doi: 10.1161/CIRCIMAGING.111.966424. Epub 2011 Dec 1.


An examination of cancer-related fatigue through proposed diagnostic criteria in a sample of cancer patients in Taiwan.

Yeh ET, Lau SC, Su WJ, Tsai DJ, Tu YY, Lai YL.

BMC Cancer. 2011 Sep 6;11:387. doi: 10.1186/1471-2407-11-387.


Balancing act during development: lessons from a SUMO-less SF-1.

Lin FM, Yeh ET.

Dev Cell. 2011 Aug 16;21(2):191-2. doi: 10.1016/j.devcel.2011.07.015.


NF-κB induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress.

Lee MH, Mabb AM, Gill GB, Yeh ET, Miyamoto S.

Mol Cell. 2011 Jul 22;43(2):180-91. doi: 10.1016/j.molcel.2011.06.017.


Onco-cardiology: the time has come.

Yeh ET.

Tex Heart Inst J. 2011;38(3):246-7. No abstract available.


Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase.

Chen CT, Yamaguchi H, Lee HJ, Du Y, Lee HH, Xia W, Yu WH, Hsu JL, Yen CJ, Sun HL, Wang Y, Yeh ET, Hortobagyi GN, Hung MC.

Mol Cancer Ther. 2011 Aug;10(8):1327-36. doi: 10.1158/1535-7163.MCT-10-1117. Epub 2011 May 24.

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