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Items: 1 to 50 of 194

1.

Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphane.

Bayat Mokhtari R, Baluch N, Morgatskaya E, Kumar S, Sparaneo A, Muscarella LA, Zhao S, Cheng HL, Das B, Yeger H.

BMC Cancer. 2019 Aug 30;19(1):864. doi: 10.1186/s12885-019-6018-1.

2.

Antibody-drug conjugate T-DM1 treatment for HER2+ breast cancer induces ROR1 and confers resistance through activation of Hippo transcriptional coactivator YAP1.

Islam SS, Uddin M, Noman ASM, Akter H, Dity NJ, Basiruzzman M, Uddin F, Ahsan J, Annoor S, Alaiya AA, Al-Alwan M, Yeger H, Farhat WA.

EBioMedicine. 2019 May;43:211-224. doi: 10.1016/j.ebiom.2019.04.061. Epub 2019 May 10.

3.

Report on the 9th international workshop on the CCN family of genes, November 2-7, 2017, Saint-Malo, France.

Yeger H, Brigstock D, Fisher G, Lau L, Leask A, Perbal B.

J Cell Commun Signal. 2018 Sep;12(3):505-511. doi: 10.1007/s12079-018-0472-4. No abstract available.

4.

Hypoxia-Targeting Drug Evofosfamide (TH-302) Enhances Sunitinib Activity in Neuroblastoma Xenograft Models.

Kumar S, Sun JD, Zhang L, Mokhtari RB, Wu B, Meng F, Liu Q, Bhupathi D, Wang Y, Yeger H, Hart C, Baruchel S.

Transl Oncol. 2018 Aug;11(4):911-919. doi: 10.1016/j.tranon.2018.05.004. Epub 2018 May 31.

5.

Transducing Airway Basal Cells with a Helper-Dependent Adenoviral Vector for Lung Gene Therapy.

Cao H, Ouyang H, Grasemann H, Bartlett C, Du K, Duan R, Shi F, Estrada M, Seigel KE, Coates AL, Yeger H, Bear CE, Gonska T, Moraes TJ, Hu J.

Hum Gene Ther. 2018 Jun;29(6):643-652. doi: 10.1089/hum.2017.201. Epub 2018 Mar 16.

PMID:
29320887
6.

Erratum to: The role of Sulforaphane in cancer chemoprevention and health benefits: a mini-review.

Mokhtari RB, Baluch N, Homayouni TS, Morgatskaya E, Kumar S, Kazemi P, Yeger H.

J Cell Commun Signal. 2018 Jun;12(2):503. doi: 10.1007/s12079-017-0408-4. No abstract available.

7.

A non-invasive magnetic resonance imaging approach for assessment of real-time microcirculation dynamics.

Ganesh T, Estrada M, Yeger H, Duffin J, Cheng HM.

Sci Rep. 2017 Aug 7;7(1):7468. doi: 10.1038/s41598-017-06983-6.

8.

The role of Sulforaphane in cancer chemoprevention and health benefits: a mini-review.

Bayat Mokhtari R, Baluch N, Homayouni TS, Morgatskaya E, Kumar S, Kazemi P, Yeger H.

J Cell Commun Signal. 2018 Mar;12(1):91-101. doi: 10.1007/s12079-017-0401-y. Epub 2017 Jul 23. Erratum in: J Cell Commun Signal. 2017 Aug 26;:.

9.

Serum sonic hedgehog (SHH) and interleukin-(IL-6) as dual prognostic biomarkers in progressive metastatic breast cancer.

Noman AS, Uddin M, Chowdhury AA, Nayeem MJ, Raihan Z, Rashid MI, Azad AK, Rahman ML, Barua D, Sultana A, Shirin A, Ferdous J, Parag RR, Rahman SM, Mahmud MR, Jerin CS, Jahan N, Siddiqua A, Ara T, Sabur EB, Alam SS, Baidya S, Akther S, Rahman MZ, Banu T, Murugan AK, Sabri S, Islam SMS, Karakas B, Aboussekhra A, Yeger H, Farhat WA, Islam SS.

Sci Rep. 2017 May 11;7(1):1796. doi: 10.1038/s41598-017-01268-4.

10.

Combination therapy in combating cancer.

Bayat Mokhtari R, Homayouni TS, Baluch N, Morgatskaya E, Kumar S, Das B, Yeger H.

Oncotarget. 2017 Jun 6;8(23):38022-38043. doi: 10.18632/oncotarget.16723. Review.

11.

Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma.

Bayat Mokhtari R, Baluch N, Ka Hon Tsui M, Kumar S, S Homayouni T, Aitken K, Das B, Baruchel S, Yeger H.

BMC Cancer. 2017 Feb 24;17(1):156. doi: 10.1186/s12885-017-3126-7.

12.

Bioengineering pediatric scaffold-free auricular cartilaginous constructs.

Akbari P, Waldman SD, Cushing SL, Papsin BC, Propst EJ, Weber JF, Yeger H, Farhat WA.

Laryngoscope. 2017 May;127(5):E153-E158. doi: 10.1002/lary.26395. Epub 2016 Nov 21.

PMID:
27868204
13.

Generating Mechanically Stable, Pediatric, and Scaffold-Free Nasal Cartilage Constructs In Vitro.

Akbari P, Waldman SD, Propst EJ, Cushing SL, Weber JF, Yeger H, Farhat WA.

Tissue Eng Part C Methods. 2016 Dec;22(12):1077-1084.

PMID:
27829311
14.
15.

CCN family of proteins: critical modulators of the tumor cell microenvironment.

Yeger H, Perbal B.

J Cell Commun Signal. 2016 Sep;10(3):229-240. Epub 2016 Aug 12.

16.

Multilabel immunofluorescence and antigen reprobing on formalin-fixed paraffin-embedded sections: novel applications for precision pathology diagnosis.

Pan J, Thoeni C, Muise A, Yeger H, Cutz E.

Mod Pathol. 2016 Jun;29(6):557-69. doi: 10.1038/modpathol.2016.52. Epub 2016 Mar 4.

17.

Report on the 8th international workshop on the CCN family of genes - Nice November 3-8, 2015.

Perbal B, Lau L, Lyons K, Kubota S, Yeger H, Fisher G.

J Cell Commun Signal. 2016 Mar;10(1):77-86. doi: 10.1007/s12079-016-0317-y. Epub 2016 Feb 26. No abstract available.

18.

Testing gene therapy vectors in human primary nasal epithelial cultures.

Cao H, Ouyang H, Ip W, Du K, Duan W, Avolio J, Wu J, Duan C, Yeger H, Bear CE, Gonska T, Hu J, Moraes TJ.

Mol Ther Methods Clin Dev. 2015 Sep 9;2:15034. doi: 10.1038/mtm.2015.34. eCollection 2015.

19.

Overexpression of sonic hedgehog in the triple negative breast cancer: clinicopathological characteristics of high burden breast cancer patients from Bangladesh.

Noman AS, Uddin M, Rahman MZ, Nayeem MJ, Alam SS, Khatun Z, Wahiduzzaman M, Sultana A, Rahman ML, Ali MY, Barua D, Ahmed I, Islam MS, Aboussekhra A, Yeger H, Farhat WA, Islam SS.

Sci Rep. 2016 Jan 5;6:18830. doi: 10.1038/srep18830.

20.

Long-Term Expression of the Human CFTR Gene in Mouse Airway via Helper-Dependent Adenoviral Vector Delivery and Transient Immunosuppression.

Cao H, Wu J, Duan C, Du K, Lee CM, Yeger H, Hu J.

Hum Gene Ther. 2016 Jan;27(1):83-91. doi: 10.1089/hum.2015.108.

PMID:
26710934
21.

Simultaneous Targeting of Bladder Tumor Growth, Survival, and Epithelial-to-Mesenchymal Transition with a Novel Therapeutic Combination of Acetazolamide (AZ) and Sulforaphane (SFN).

Islam SS, Mokhtari RB, Akbari P, Hatina J, Yeger H, Farhat WA.

Target Oncol. 2016 Apr;11(2):209-27. doi: 10.1007/s11523-015-0386-5.

PMID:
26453055
22.

Augmented 5-HT Secretion in Pulmonary Neuroepithelial Bodies from PHD1 Null Mice.

Livermore S, Pan J, Yeger H, Ratcliffe P, Bishop T, Cutz E.

Adv Exp Med Biol. 2015;860:309-13. doi: 10.1007/978-3-319-18440-1_35.

PMID:
26303495
23.

Come together, right now….

Yeger H.

J Cell Commun Signal. 2015 Sep;9(3):283-4. doi: 10.1007/s12079-015-0301-y. Epub 2015 Jul 25.

24.

It's all in your gut and mind.

Yeger H.

J Cell Commun Signal. 2015 Mar;9(1):105-7. doi: 10.1007/s12079-015-0285-7. Epub 2015 Apr 15.

25.

Sonic hedgehog (Shh) signaling promotes tumorigenicity and stemness via activation of epithelial-to-mesenchymal transition (EMT) in bladder cancer.

Islam SS, Mokhtari RB, Noman AS, Uddin M, Rahman MZ, Azadi MA, Zlotta A, van der Kwast T, Yeger H, Farhat WA.

Mol Carcinog. 2016 May;55(5):537-51. doi: 10.1002/mc.22300. Epub 2015 Mar 1.

PMID:
25728352
26.

The evolution of human communication.

Yeger H.

J Cell Commun Signal. 2015 Sep;9(3):289-90. doi: 10.1007/s12079-015-0286-6. Epub 2015 Feb 25. No abstract available.

27.

Pulmonary neuroepithelial bodies are polymodal airway sensors: evidence for CO2/H+ sensing.

Livermore S, Zhou Y, Pan J, Yeger H, Nurse CA, Cutz E.

Am J Physiol Lung Cell Mol Physiol. 2015 Apr 15;308(8):L807-15. doi: 10.1152/ajplung.00208.2014. Epub 2015 Feb 6.

28.

Aggregates of mutant CFTR fragments in airway epithelial cells of CF lungs: new pathologic observations.

Du K, Karp PH, Ackerley C, Zabner J, Keshavjee S, Cutz E, Yeger H.

J Cyst Fibros. 2015 Mar;14(2):182-93. doi: 10.1016/j.jcf.2014.09.012. Epub 2014 Oct 28.

29.

Immunohistochemical characterization of the chemosensory pulmonary neuroepithelial bodies in the naked mole-rat reveals a unique adaptive phenotype.

Pan J, Park TJ, Cutz E, Yeger H.

PLoS One. 2014 Nov 19;9(11):e112623. doi: 10.1371/journal.pone.0112623. eCollection 2014.

30.

The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation.

Pasyk S, Molinski S, Ahmadi S, Ramjeesingh M, Huan LJ, Chin S, Du K, Yeger H, Taylor P, Moran MF, Bear CE.

Proteomics. 2015 Jan;15(2-3):447-61. doi: 10.1002/pmic.201400218. Epub 2014 Dec 17.

PMID:
25330774
31.

Manganese-enhanced magnetic resonance imaging for early detection and characterization of breast cancers.

Alhamami M, Bayat Mokhtari R, Ganesh T, Tchouala Nofiele J, Yeger H, Margaret Cheng HL.

Mol Imaging. 2014;13. doi: 10.2310/7290.2014.00021.

PMID:
25060340
32.

Carbonic anhydrase II mediates malignant behavior of pulmonary neuroendocrine tumors.

Zhou Y, Mokhtari RB, Pan J, Cutz E, Yeger H.

Am J Respir Cell Mol Biol. 2015 Feb;52(2):183-92. doi: 10.1165/rcmb.2014-0054OC.

PMID:
25019941
33.

VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface.

Eckford PD, Ramjeesingh M, Molinski S, Pasyk S, Dekkers JF, Li C, Ahmadi S, Ip W, Chung TE, Du K, Yeger H, Beekman J, Gonska T, Bear CE.

Chem Biol. 2014 May 22;21(5):666-78. doi: 10.1016/j.chembiol.2014.02.021. Epub 2014 Apr 10.

34.

Manganese-enhanced MRI of minimally gadolinium-enhancing breast tumors.

Ganesh T, Mokhtari RB, Alhamami M, Yeger H, Cheng HL.

J Magn Reson Imaging. 2015 Mar;41(3):806-13. doi: 10.1002/jmri.24608. Epub 2014 Mar 4.

PMID:
24591227
35.

TGF-β1 induces EMT reprogramming of porcine bladder urothelial cells into collagen producing fibroblasts-like cells in a Smad2/Smad3-dependent manner.

Islam SS, Mokhtari RB, El Hout Y, Azadi MA, Alauddin M, Yeger H, Farhat WA.

J Cell Commun Signal. 2014 Mar;8(1):39-58. doi: 10.1007/s12079-013-0216-4. Epub 2013 Dec 12.

36.

Efficient gene delivery to pig airway epithelia and submucosal glands using helper-dependent adenoviral vectors.

Cao H, Machuca TN, Yeung JC, Wu J, Du K, Duan C, Hashimoto K, Linacre V, Coates AL, Leung K, Wang J, Yeger H, Cutz E, Liu M, Keshavjee S, Hu J.

Mol Ther Nucleic Acids. 2013 Oct 8;2:e127. doi: 10.1038/mtna.2013.55.

37.

Combination of carbonic anhydrase inhibitor, acetazolamide, and sulforaphane, reduces the viability and growth of bronchial carcinoid cell lines.

Mokhtari RB, Kumar S, Islam SS, Yazdanpanah M, Adeli K, Cutz E, Yeger H.

BMC Cancer. 2013 Aug 8;13:378. doi: 10.1186/1471-2407-13-378.

38.

Tumor dynamics in response to antiangiogenic therapy with oral metronomic topotecan and pazopanib in neuroblastoma xenografts.

Kumar S, Mokhtari RB, Oliveira ID, Islam S, Toledo SR, Yeger H, Baruchel S.

Transl Oncol. 2013 Aug 1;6(4):493-503. Print 2013 Aug.

39.

Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis.

Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA.

PLoS One. 2013 Apr 19;8(4):e61340. doi: 10.1371/journal.pone.0061340. Print 2013.

40.

CD271(+) bone marrow mesenchymal stem cells may provide a niche for dormant Mycobacterium tuberculosis.

Das B, Kashino SS, Pulu I, Kalita D, Swami V, Yeger H, Felsher DW, Campos-Neto A.

Sci Transl Med. 2013 Jan 30;5(170):170ra13. doi: 10.1126/scitranslmed.3004912.

41.

Hyperplasia of pulmonary neuroepithelial bodies (NEB) in lungs of prolyl hydroxylase -1(PHD-1) deficient mice.

Pan J, Yeger H, Ratcliffe P, Bishop T, Cutz E.

Adv Exp Med Biol. 2012;758:149-55. doi: 10.1007/978-94-007-4584-1_21.

42.

Recent advances and contraversies on the role of pulmonary neuroepithelial bodies as airway sensors.

Cutz E, Pan J, Yeger H, Domnik NJ, Fisher JT.

Semin Cell Dev Biol. 2013 Jan;24(1):40-50. doi: 10.1016/j.semcdb.2012.09.003. Epub 2012 Sep 26. Review.

PMID:
23022441
43.

Preclinical models for pediatric solid tumor drug discovery: current trends, challenges and the scopes for improvement.

Kumar S, Mokhtari RB, Yeger H, Baruchel S.

Expert Opin Drug Discov. 2012 Nov;7(11):1093-106. doi: 10.1517/17460441.2012.722077. Epub 2012 Sep 24. Review.

PMID:
22998522
44.

NOX2 (gp91phox) is a predominant O2 sensor in a human airway chemoreceptor cell line: biochemical, molecular, and electrophysiological evidence.

Buttigieg J, Pan J, Yeger H, Cutz E.

Am J Physiol Lung Cell Mol Physiol. 2012 Oct 1;303(7):L598-607. doi: 10.1152/ajplung.00170.2012. Epub 2012 Aug 3.

45.

HIF-2α suppresses p53 to enhance the stemness and regenerative potential of human embryonic stem cells.

Das B, Bayat-Mokhtari R, Tsui M, Lotfi S, Tsuchida R, Felsher DW, Yeger H.

Stem Cells. 2012 Aug;30(8):1685-95. doi: 10.1002/stem.1142.

46.

Impact of bladder-derived acellular matrix, growth factors, and extracellular matrix constituents on the survival and multipotency of marrow-derived mesenchymal stem cells.

Antoon R, Yeger H, Loai Y, Islam S, Farhat WA.

J Biomed Mater Res A. 2012 Jan;100(1):72-83. doi: 10.1002/jbm.a.33230. Epub 2011 Oct 4.

PMID:
21972045
47.

Metronomic oral topotecan with pazopanib is an active antiangiogenic regimen in mouse models of aggressive pediatric solid tumor.

Kumar S, Mokhtari RB, Sheikh R, Wu B, Zhang L, Xu P, Man S, Oliveira ID, Yeger H, Kerbel RS, Baruchel S.

Clin Cancer Res. 2011 Sep 1;17(17):5656-67. doi: 10.1158/1078-0432.CCR-11-0078. Epub 2011 Jul 25.

48.

Elf3 plays a role in regulating bronchiolar epithelial repair kinetics following Clara cell-specific injury.

Oliver JR, Kushwah R, Wu J, Pan J, Cutz E, Yeger H, Waddell TK, Hu J.

Lab Invest. 2011 Oct;91(10):1514-29. doi: 10.1038/labinvest.2011.100. Epub 2011 Jun 27.

49.

The effect of N-acetylcysteine on the antitumor activity of ifosfamide.

Chen N, Hanly L, Rieder M, Yeger H, Koren G.

Can J Physiol Pharmacol. 2011 May;89(5):335-43. doi: 10.1139/y11-028. Epub 2011 May 24.

PMID:
21609276
50.

SBDS-deficiency results in deregulation of reactive oxygen species leading to increased cell death and decreased cell growth.

Ambekar C, Das B, Yeger H, Dror Y.

Pediatr Blood Cancer. 2010 Dec 1;55(6):1138-44. doi: 10.1002/pbc.22700.

PMID:
20979173

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